EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

copper sulfate
sulfuric acid, copper (2+) salt (1:1)

Supplier Sponsors

Name:copper sulfate
CAS Number: 7758-98-7Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:231-847-6
FDA UNII: KUW2Q3U1VV
Nikkaji Web:J3.756G
MDL:MFCD00010981
Molecular Weight:159.60780000
Formula:Cu O4 S
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:nutrient supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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 FDA/DG SANTE Petitions, Reviews, Notices:
184.1261 Copper (cupric) sulfate View - review
JECFA Food Additive: Cupric Sulfate
FDA Mainterm (SATF):7758-98-7 ; COPPER SULFATE
FDA Regulation:
FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1261 Copper sulfate.


FDA PART 582 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 582.80 Trace minerals added to animal feeds.
 
Physical Properties:
Appearance:deep blue to blue crystals (est)
Assay: 98.50 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:3.60300 @ 25.00 °C.
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 9.62e+004 mg/L @ 25 °C (est)
 alcohol, slightly
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
 
Suppliers:
Allan Chemical
Copper Sulfate
American Elements
Copper Sulfate 99%
Odor: characteristic
Use: Copper Sulfate is a water soluble Copper source for uses compatible with sulfates. Copper Sulfate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements copper sulfate facilities manufacture using a process that was developed to provide a non-caking high purity copper sulfate suitable for both industrial and agricultural applications. Copper Sulfate is particularly useful in demanding applications, such as copper plating and electroless copper plating. The product contains no non-caking agents. We also produce Copper Sulfate Solution. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
Cupric Sulfate
Balchem
Copper Sulfate
VitaShure®
Flavor: characteristic
Vitashure is an extensive line of microencapsulated vitamins, minerals, amino acids, and bioactive substances, specifically designed for the supplementation and fortification industries.
BOC Sciences
For experimental / research use only.
Copper(II) sulfate
Charkit Chemical
CUPRIC SULFATE PENTAHYDRATE UNMILLED
Charkit Chemical
CUPRIC SULFATE PENTAHYDRATE
ECSA Chemicals
COPPER (II) SULPHATE ANHYDROUS RPE-FOR ANALY
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
ECSA Chemicals
COPPERSULFATE WITH ANTICAKING
George Uhe Company
Copper Sulfate
Glentham Life Sciences
Copper(II) sulfate, anhydrous, 98%
Glentham Life Sciences
Copper(II) sulfate, anhydrous, Ph. Eur. grade
Jost Chemical
Cupric Sulfate Anhydrous Purified Low HM Powder
Jost Chemical
Cupric Sulfate Anhydrous Purified Powder
Kraft Chemical
Copper Sulfate
Krunal Group
Copper Sulphate
Penta International
CUPRIC SULFATE MONOHYDRATE POWDER PURIFIED
Sigma-Aldrich: Aldrich
For experimental / research use only.
Copper(II) sulfate anhydrous, powder, =99.99% trace metals basis
Silver Fern Chemical
Copper Sulfate
Odor: characteristic
Use: Copper Sulfate has many applications in industries such as agriculture, textiles, leathers, coatings, pharmaceuticals, construction, petroleum, metal manufacturing, and others.
Wedor Corporation
COPPER SULFATE (CRYSTALS AND GRANULAR)
Zhong Ya Chemical
Copper Sulfate Tech Grade
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 300 mg/kg
"Antifungal Compounds," Siegel, M.R., and H.D. Sisler, eds., 2 vols., New York, Marcel Dekker 1977Vol. 1, Pg. 507, 1977.

oral-child TDLo 150 mg/kg
BLOOD: OTHER HEMOLYSIS WITH OR WITHOUT ANEMIA KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
American Journal of Diseases of Children. Vol. 131, Pg. 149, 1977.

intravenous-frog LDLo 25 mg/kg
"Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 76, 1955.

intravenous-guinea pig LDLo 2 mg/kg
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.

oral-human LDLo 50 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BLOOD: HEMORRHAGE KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
JAMA, Journal of the American Medical Association. Vol. 235, Pg. 801, 1976.

oral-human TDLo 11 mg/kg
GASTROINTESTINAL: GASTRITIS GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING
Lancet. Vol. 2, Pg. 700, 1960.

oral-man LDLo 857 mg/kg
GASTROINTESTINAL: NAUSEA OR VOMITING
Archiv fuer Toxikologie. Vol. 17, Pg. 20, 1958.

intraperitoneal-mouse LD50 7182 ug/kg
Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 256, Pg. 1043, 1963.

intravenous-mouse LD50 23300 ug/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.

oral-mouse LD50 369 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.

intravenous-rabbit LD50 10 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" BEHAVIORAL: FOOD INTAKE (ANIMAL) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 301, 1949.

intraperitoneal-rat LD50 20 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.

intravenous-rat LD50 48900 ug/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Indian Journal of Pharmacology. Vol. 23, Pg. 153, 1991.

unreported-rat LD50 520 mg/kg
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 26(6), Pg. 21, 1982.

Dermal Toxicity:
subcutaneous-rat LD50 43 mg/kg
Proceedings of the European Society of Toxicology. Vol. 16, Pg. 252, 1975.

subcutaneous-mouse LDLo 500 ug/kg
Tokyo Joshi Ika Daigaku Zasshi. Journal of Tokyo Women's Medical College. Vol. 48, Pg. 313, 1978.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
nutrient supplements
Recommendation for copper sulfate usage levels up to:
 not for fragrance use.
 
Recommendation for copper sulfate flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the safety and efficacy of copper compounds (E4) as feed additives for all animal species: cupric sulphate pentahydrate based on a dossier submitted by Manica S.p.A.
View page or View pdf

Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance Copper (I), copper (II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper (I) oxide, Bordeaux mixture
View page or View pdf

Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf

Peer review of the pesticide risk assessment of the active substance copper compounds copper(I), copper(II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper(I) oxide, Bordeaux mixture
View page or View pdf

Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for copper compounds copper(I), copper(II) variants namely copper hydroxide, copper oxychloride, tribasic copper sulfate, copper(I) oxide, Bordeaux mixture in light of confirmatory data
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Daily Med:search
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):7758-98-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24462
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 3077
WGK Germany:3
copper sulfate
Chemidplus:0007758987
EPA/NOAA CAMEO:hazardous materials
RTECS:7758-98-7
 
References:
 copper sulfate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7758-98-7
Pubchem (cid):24462
Pubchem (sid):134989998
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C18713
HMDB (The Human Metabolome Database):Search
FooDB:FDB014051
Export Tariff Code:2833.25.0000
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•usepaopp pesticide code 024408; trade names: none listed. •grade: technical, cp, nf, also sold as monohydrate. available as crystals or powder. •crystals; wettable powder; suspension concentrate •various crystal sizes: medium, large liquid, powder (snow) form, granular, water soluble •mixtures: (copper sulfate +) cymoxanil; cymoxanil + mancozeb; folpet; mancozeb; maneb; sulfur; zineb; copper oxuchloride + mancozeb + oxadixyl; copper carbonate (basic) + copper oxychloride + mancozeb. •anhydrous form contains nearly 50% copper, the commonly used pentahydrate form contains 25.5% copper. •in form of bordeaux mixt ( contains 1-3% copper sulfate) . •aqua maid permanent algaecide; solution-ready to use, 6.33% copper sulfate (anhydrous) •sa-50 brand copper sulfate granular crystals; crystalline, 99.0% copper sulfate. •tobacco states brand copper sulfate; technical chemical, 99.0% copper sulfate. •bonide root destroyer; crystalline, 99.0% copper sulfate. •phelps triangle brand copper sulfate; crystalline, 99.0% copper sulfate. •snow crystal copper sulfate; granular-pelleted or crystal, 99.0% copper sulfate. •all clear!! root destroyer; crystalline, 99.0% copper sulfate. •aquatronic snail-a-cide dri-pac snail powder; solution-ready to use, 99.0% copper sulfate. •granular crystals copper sulfate; technical chemical, 99.0% copper sulfate. •chemline copper sulfate powder; soluble concn, 99.0% copper sulfate.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 blue stone
 copper (2+) sulfate(1:1)
 copper monosulfate
 copper sulphate
 copper(2+) sulfate
 copper(II) sulfate
 copper(II) sulphate
 cupric sulfate
 sulfuric acid copper (2+) salt (1:1)
 sulfuric acid copper(2+) salt (1:1)
 sulfuric acid, copper (2+) salt (1:1)
 

Articles:

Info:EVALUATION OF CERTAIN FOOD ADDITIVES AND CONTAMINANTS
PubMed:Effect of a tea tree oil and organic acid footbath solution on digital dermatitis in dairy cows.
PubMed:Delineation of vagal emetic pathways: intragastric copper sulfate-induced emesis and viral tract tracing in musk shrews.
PubMed:Biocide and copper tolerance in enterococci from different sources.
PubMed:Copper supplementation at 8 mg neither affects circulating lipids nor liver function in apparently healthy Chilean men.
PubMed:Molecular structure of citric acid cross-linked starch films.
PubMed:Analytical determination of bioactive compounds as an indication of fruit quality.
PubMed:Carbonylation of myofibrillar proteins through the maillard pathway: effect of reducing sugars and reaction temperature.
PubMed:Observations on the design and use of footbaths for the control of infectious hoof disease in dairy cattle.
PubMed:Flocculation and haze removal from crude beer using in-house produced laccase from Trametes versicolor cultured on brewer's spent grain.
PubMed:Copper resistance and its relationship to erythromycin resistance in Enterococcus isolates from bovine milk samples in Korea.
PubMed:Effects of olive leaves extract on LDL oxidation induced-CuSO(4) in vitro.
PubMed:Effectiveness of different footbathing frequencies using copper sulfate in the control of digital dermatitis in dairy cows.
PubMed:Evaluation of intraocular reactivity to metallic and ethylene oxide contaminants of medical devices in a rabbit model.
PubMed:Dual role of selected antioxidants found in dietary supplements: crossover between anti- and pro-oxidant activities in the presence of copper.
PubMed:Chitinolytic and chitosanolytic activities from crude cellulase extract produced by A. niger grown on apple pomace through Koji fermentation.
PubMed:Phenolics composition and antioxidant activity of wine produced from spine grape (Vitis davidii Foex) and Cherokee rose (Rosa laevigata Michx.) fruits from South China.
PubMed:Effects of copper on the post acidification of fermented milk by St. thermophilus.
PubMed:A modified alkaline Comet assay for in vivo detection of oxidative DNA damage in Drosophila melanogaster.
PubMed:Identification of ethyl 2-sulfanylacetate as an important off-odor compound in white wines.
PubMed:Sublethal concentrations of waterborne copper induce cellular stress and cell death in zebrafish embryos and larvae.
PubMed:Copper ability to induce premature senescence in human fibroblasts.
PubMed:Effect of type of muscle and Cu supplementation on trace element concentrations in cattle meat.
PubMed:The influence of zinc and copper on the latency period for feeding and the food uptake in common carp, Cyprinus carpio L.
PubMed:Evolution of 3-mercaptohexanol, hydrogen sulfide, and methyl mercaptan during bottle storage of Sauvignon blanc wines. Effect of glutathione, copper, oxygen exposure, and closure-derived oxygen.
PubMed:Avoidance tests with Folsomia candida for the assessment of copper contamination in agricultural soils.
PubMed:Effectiveness of different footbath solutions in the treatment of digital dermatitis in dairy cows.
PubMed:Searching for specific responses to copper exposure: an in vitro copper challenge in peripheral mononuclear cells.
PubMed:Low pH dye decolorization with ascomycete Lamprospora wrightii laccase.
PubMed:Importance of extract standardization and in vitro/ex vivo assay selection for the evaluation of antioxidant activity of botanicals: a case study on three Rosmarinus officinalis L. extracts.
PubMed:Cloning and occurrence of czrC, a gene conferring cadmium and zinc resistance in methicillin-resistant Staphylococcus aureus CC398 isolates.
PubMed:Population level indicators of stress: Effects of two heavy metals (copper and mercury) on the growth of Lecane quadridentata (Ehrenberg, 1830) (Rotifera: Lecanidae).
PubMed:Strawberry consumption is associated with increased antioxidant capacity in serum.
PubMed:A novel Method for the selective recovery and purification of gamma-polyglutamic acid from Bacillus licheniformis fermentation broth.
PubMed:Inactivation of Cronobacter spp. (Enterobacter sakazakii) in infant formula using lactic acid, copper sulfate and monolaurin.
PubMed:[Supposed role of "metabolic memory" in formation of response reaction to stress-factors in young and adult organisms].
PubMed:Effect of acute copper sulfate exposure on olfactory responses to amino acids and pheromones in goldfish (Carassius auratus).
PubMed:Olvanil: a non-pungent TRPV1 activator has anti-emetic properties in the ferret.
PubMed:Acute copper supplementation does not inhibit non-heme iron bioavailability in humans.
PubMed:Synergistic antifungal activity of sodium hypochlorite, hydrogen peroxide, and cupric sulfate against Penicillium digitatum.
PubMed:Influence of estrogens on copper indicators: in vivo and in vitro studies.
PubMed:The effects of dietary additives on faecal levels of Lactobacillus spp., coliforms, and Escherichia coli, and faecal prevalence of Salmonella spp. and Campylobacter spp. in US production nursery swine.
PubMed:Protective effects of leaf extract of Zanthoxylum ailanthoides on oxidation of low-density lipoprotein and accumulation of lipid in differentiated THP-1 cells.
PubMed:Sensory attributes of complex tasting divalent salts are mediated by TRPM5 and TRPV1 channels.
PubMed:Enhancement by Copper(II) of the voltammetric signal of vitamin B2 applied to its determination in breakfast cereals.
PubMed:Dietary iron alters waterborne copper-induced gene expression in soft water acclimated zebrafish (Danio rerio).
PubMed:Microbial ecology shifts in the ileum of broilers during feed withdrawal and dietary manipulations.
PubMed:The effect of an acidic, copper sulfate-based commercial sanitizer on indicator, pathogenic, and spoilage bacteria associated with broiler chicken carcasses when applied at various intervention points during poultry processing.
PubMed:Mechanisms of copper toxicity in Saccharomyces cerevisiae determined by microarray analysis.
PubMed:Milk thistle extracts inhibit the oxidation of low-density lipoprotein (LDL) and subsequent scavenger receptor-dependent monocyte adhesion.
PubMed:Effect of nutrition on toxicity of contaminants to the epibenthic amphipod Melita plumulosa.
PubMed:Chemical residuals in the environment and on chicken carcasses associated with scalding chickens in an acidic, copper sulfate-based commercial sanitizer during poultry processing.
PubMed:Copper and liver function indicators vary depending on the female hormonal cycle and serum hormone binding globulin (SHBG) concentration in healthy women.
PubMed:Comparative effects of copper, iron, vanadium and titanium on low density lipoprotein oxidation in vitro.
PubMed:[Zinc and copper content in individual components used to prepare pediatric total nutrition mixtures].
PubMed:Preventing cell death induced by carbonyl stress, oxidative stress or mitochondrial toxins with vitamin B anti-AGE agents.
PubMed:A rabbit model of Alzheimer's disease: valid at neuropathological, cognitive, and therapeutic levels.
PubMed:Antioxidant activities of Toona Sinensis leaves extracts using different antioxidant models.
PubMed:Planktonic microbial community responses to added copper.
PubMed:[Effects of copper supplementation on lipid profiles in elderly patients with copper deficiency].
PubMed:Clinicopathological analysis of hematological disorders in tube-fed patients with copper deficiency.
PubMed:Copper induction of lactate oxidase of Lactococcus lactis: a novel metal stress response.
PubMed:Folate deprivation and copper exposure potentiate reactive oxygen species generation and chromosomal DNA loss but not mitochondrial DNA deletions in rat hepatocytes.
PubMed:Copper resistance in Enterococcus faecium, mediated by the tcrB gene, is selected by supplementation of pig feed with copper sulfate.
PubMed:In long-term bedridden elderly patients with dietary copper deficiency, biochemical markers of bone resorption are increased with copper supplementation during 12 weeks.
PubMed:Effects of copper source and concentration on in vitro phytate phosphorus hydrolysis by phytase.
PubMed:Hibiscus anthocyanins-rich extract inhibited LDL oxidation and oxLDL-mediated macrophages apoptosis.
PubMed:Differential response of interleukin-2 production to chronic copper supplementation in healthy humans.
PubMed:An in vitro study on the postinfection activities of copper hydroxide and copper sulfate against conidia of Venturia inaequalis.
PubMed:Protective effect of dietary capsaicin on induced oxidation of low-density lipoprotein in rats.
PubMed:Early histological and functional effects of chronic copper exposure in rat liver.
PubMed:Influence of orange juice in the levels and in the genotoxicity of iron and copper.
PubMed:Consumption of argan oil may have an antiatherogenic effect by improving paraoxonase activities and antioxidant status: Intervention study in healthy men.
PubMed:Oral sensations from iron and copper sulfate.
PubMed:Induction of micronuclei and binuclei in blood, gill and liver cells of fishes subchronically exposed to cadmium chloride and copper sulphate.
PubMed:Relationship between copper, glycopeptide, and macrolide resistance among Enterococcus faecium strains isolated from pigs in Denmark between 1997 and 2003.
PubMed:DNA damage in leukocytes of mice treated with copper sulfate.
PubMed:Effects of copper and zinc source on performance and humoral immune response of newly received, lightweight beef heifers.
PubMed:Cholesterol, copper, and accumulation of thioflavine S-reactive Alzheimer's-like amyloid beta in rabbit brain.
PubMed:Susceptibility of different bacterial species isolated from food animals to copper sulphate, zinc chloride and antimicrobial substances used for disinfection.
PubMed:The effect of copper on the death rate of Salmonella typhimurium DT104:30 in food substrates acidified with organic acids.
PubMed:Inhibitory effect of hot-water extract from dried fruit of Crataegus pinnatifida on low-density lipoprotein (LDL) oxidation in cell and cell-free systems.
PubMed:Confirmation of an acute no-observed-adverse-effect and low-observed-adverse-effect level for copper in bottled drinking water in a multi-site international study.
PubMed:Zinc and copper: proposed fortification levels and recommended zinc compounds.
PubMed:The effect of vitamin E supplementation on discoloration of injection-site lesions in retail cuts and the greening reaction observed in injection-site lesions in muscles of the chuck.
PubMed:Copper modulates the degradation of copper chaperone for Cu,Zn superoxide dismutase by the 26 S proteosome.
PubMed:Gastric response to acute copper exposure.
PubMed:Metal-catalyzed oxidation of a structured lipid model emulsion.
PubMed:Age and copper intake do not affect copper absorption, measured with the use of 65Cu as a tracer, in young infants.
PubMed:A suggested method for the prediction of the oxidation resistance of low density lipoprotein by determination of the lag time.
PubMed:Effects of Cu+2 and pH on the fitness of Ceriodaphnia dubia (Richard 1894) (Crustacea, Cladocera) in microcosm experiments.
PubMed:Effect of acute copper exposure on gastrointestinal permeability in healthy volunteers.
PubMed:The effects of adding xylanase, vitamin C and copper sulphate to wheat-based diets on broiler performance.
PubMed:Solubility and relative absorption of copper, iron, and zinc in two milk-based liquid infant formulae.
PubMed:Role of alpha-MSH in the regulation of consummatory behavior: immunohistochemical evidence.
PubMed:Nausea threshold in apparently healthy individuals who drink fluids containing graded concentrations of copper.
PubMed:Interactions of selenium compounds with other antioxidants in DNA damage and apoptosis in human normal keratinocytes.
PubMed:Determination of the taste threshold of copper in water.
PubMed:Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro.
PubMed:Cytotoxicity of MEIC Chemicals Nos. 11-30 in 3T3 Mouse Fibroblasts with and without Microsomal Activation.
PubMed:Oxidized LDL from subjects with different dietary habits modifies atherogenic processes in endothelial and smooth muscle cells.
PubMed:Inhibitory effect of quercetin metabolites and their related derivatives on copper ion-induced lipid peroxidation in human low-density lipoprotein.
PubMed:Increase of antioxidative potential of rat plasma by oral administration of proanthocyanidin-rich extract from grape seeds.
PubMed:Dietary habits affect the susceptibility of low-density lipoprotein to oxidation.
PubMed:Consequences of treatment with dexamethasone in rats on the susceptibility of total plasma and isolated lipoprotein fractions to copper oxidation.
PubMed:Optimization and validation of a minicolumn method for determining aflatoxins in copra meal.
PubMed:Detection and identification of wild yeasts in lager breweries.
PubMed:Proliferative effects of oxidized low-density lipoprotein on vascular smooth muscle cells: role of dietary habits.
PubMed:Yolk and serum cholesterol and production traits, as affected by incorporating a supraoptimal amount of copper in the diet of the leghorn hen.
PubMed:Characterization of extracellular beta-lactamases from penicillin G-resistant cells of Streptococcus thermophilus.
PubMed:Enhancement of antioxidative ability of rat plasma by oral administration of (-)-epicatechin.
PubMed:Copper, iron, zinc, and manganese in dietary supplements, infant formulas, and ready-to-eat breakfast cereals.
PubMed:Estimating the concentration of beta-carotene required for maximal protection of low-density lipoproteins in women.
PubMed:Studies on the feeding of cupric sulfate pentahydrate, cupric citrate, and copper oxychloride to broiler chickens.
PubMed:The effect of dietary supplementation with copper sulfate or tribasic copper chloride on broiler performance, relative copper bioavailability, and dietary prooxidant activity.
PubMed:Possible involvement of radical reactions in desialylation of LDL.
PubMed:Utilization of copper in copper proteinate, copper lysine, and cupric sulfate using the rat as an experimental model.
PubMed:Oxidation of alpha-tocopherol during the peroxidation of dilinoleoylphosphatidylcholine in liposomes.
PubMed:Effect of medicating ingredients and other additives on microflora present on swine and chicken feeds from a Manitoba mill.
PubMed:Increase of LDL susceptibility to oxidation occurring after intense, long duration aerobic exercise.
PubMed:The role of conditioned taste aversion in the hypophagia induced by intraperitoneal epinephrine and glucose.
PubMed:The role of feed consumption and feed efficiency in copper-stimulated growth.
PubMed:Structural and functional responses of a freshwater plankton community to acute copper stress.
PubMed:Subchronic toxicity of cupric sulfate administered in drinking water and feed to rats and mice.
PubMed:Effect of copper level and source (copper lysine vs copper sulfate) on copper status, performance, and immune response in growing steers fed diets with or without supplemental molybdenum and sulfur.
PubMed:Pica in rats is analogous to emesis: an animal model in emesis research.
PubMed:Metal uptake by mycelia during submerged growth and by sporocarps of an edible fungus Volvariella volvacea.
PubMed:[Alimentary methods of maintaining the superoxide dismutase activity in the tissues of rats during growth of a transplanted tumor and administration of carminomycin].
PubMed:Site-specific oxidation of angiotensin I by copper(II) and L-ascorbate: conversion of histidine residues to 2-imidazolones.
PubMed:Advances in the control of foot rot in sheep.
PubMed:Oral copper supplementation: effect on copper and zinc balance during acute gastroenteritis in infants.
PubMed:Substances that interfere with guaiac card tests: implications for gastric aspirate testing.
PubMed:Bioavailability of copper to rats from various foodstuffs and in the presence of different carbohydrates.
PubMed:Vasopressin release in response to nausea-producing agents and cholecystokinin in monkeys.
PubMed:Pairing pentobarbital with one toxin causes it to attenuate taste aversions produced by a different toxin: implications for conditioned antisickness theory.
PubMed:Inactivation of metalloenzymes by food constituents.
PubMed:[A multicomponent additive intended for preparing infant milk mixtures enriched with essential and protective factors].
PubMed:Screening and quantitation of ochratoxin A in corn, peanuts, beans, rice, and cassava.
PubMed:Effect of dietary copper on litter microbial population and broiler performance.
PubMed:Effects of copper sulfate supplement on growth, tissue concentration, and ruminal solubilities of molybdenum and copper in sheep fed low and high molybdenum diets.
PubMed:Feed additive studies with newly weaned pigs: efficacy of supplemental copper, antibiotics and organic acids.
PubMed:A pharmacological perspective of drugs used in establishing conditioned food aversions.
PubMed:Comparison of dietary hydrated copper sulphate, dietary zinc oxide and a direct method for inducing a moult in laying hens.
PubMed:Effect of 3-nitro-4-hydroxyphenylarsonic acid on copper utilization by the pig, rat and chick.
PubMed:[Trials with organic and inorganic copper compounds. 2. Effects on liver protein synthesis and growth in rats].
PubMed:Effects of propionic acid and of copper sulfate on the nutritional value of diets containing moldy corn for broiler chicks.
PubMed:The effects of dietary intake and of dietary concentration of copper sulphate on the laying domestic fowl: effects on some aspects of lipid, carbohydrate and amino acid metabolism.
PubMed:The effects of dietary intake and of dietary concentration of copper sulphate on the laying domestic fowl: effects on laying performance and tissue mineral contents.
PubMed:The performance of laying hens as affected by copper sulfate and methionine level.
PubMed:Identification of the component responsible for the effects of added dietary copper sulphate in the female domestic fowl.
PubMed:Tibial dyschondroplasia in broilers: comparison to dietary additives and strains.
PubMed:An attempt to distinguish between the direct and indirect effects, in the laying domestic fowl, of added dietary copper sulphate.
PubMed:Serum copper concentrations in sick and well preterm infants.
PubMed:Food intake and body weight: effects of specific and non-specific lesions in the midbrain path of the ascending noradrenergic neurons of the rat.
PubMed:[Concentration and subcellular distribution of iron and copper in the pig liver. II. Studies on the livers of porkers and swine for slaughter with regard to the addition of copper sulfate to the diet].
PubMed:Influence of dietary cupric sulfate on the response of young turkeys to penicillin-streptomycin (1:3).
PubMed:The short-term effects of three molluscicides on the microflora and microfauna of small, biologically stable ponds in Southern Rhodesia.
 
Notes:
a sulfate salt of copper. it is a potent emetic and is used as an antidote for poisoning by phosphorus. it also can be used to prevent the growth of algae. Copper sulfate is a commonly included chemical in children's chemistry sets and is often used to grow crystals in schools and in copper plating experiments. Due to its toxicity, it is not recommended for small children. Copper sulfate is often used to demonstrate an exothermic reaction, in which steel wool or magnesium ribbon is placed in an aqueous solution of CuSO4. It is used in school chemistry courses to demonstrate the principle of mineral hydration. The pentahydrate form, which is blue, is heated, turning the copper sulfate into the anhydrous form which is white, while the water that was present in the pentahydrate form evaporates. When water is then added to the anhydrous compound, it turns back into the pentahydrate form, regaining its blue color, and is known as blue copperas.; Copper sulfate pentahydrate is a fungicide. Mixed with lime it is called Bordeaux mixture and used to control fungus on grapes, melons, and other berries. Another application is Cheshunt compound, a mixture of copper sulfate and ammonium carbonate used in horticulture to prevent damping off in seedlings. Its use as a herbicide is not agricultural, but instead for control of invasive aquatic plants and the roots of plants near pipes containing water. It is used in swimming pools as an algaecide. A dilute solution of copper sulfate is used to treat aquarium fish for parasitic infections, and is also used to remove snails from aquariums. Copper ions are highly toxic to fish, care must be taken with the dosage. Most species of algae can be controlled with very low concentrations of copper sulfate. Copper sulfate inhibits growth of bacteria such as E. coli.; Copper(II) sulfate is the chemical compound with the formula CuSO4. This salt exists as a series of compounds that differ in their degree of hydration. The anhydrous form is a pale green or gray-white powder, whereas the pentahydrate (CuSO4·5H2O), the most commonly encountered salt, is bright blue. The anhydrous form occurs as a rare mineral known as chalcocyanite. The hydrated copper sulfate occurs in nature as chalcanthite (pentahydrate), and two more rare ones: bonattite (trihydrate) and boothite (heptahydrate). Archaic names for copper(II) sulfate are "blue vitriol" and "bluestone".
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