EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

citric acid monohydrate
1,2,3-propanetricarboxylic acid, 2-hydroxy-, monohydrate

Supplier Sponsors

Name:2-hydroxypropane-1,2,3-tricarboxylic acid;hydrate
CAS Number: 5949-29-1Picture of molecule3D/inchi
FDA UNII: 2968PHW8QP
Molecular Weight:210.13930000
Formula:C6 H10 O8
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:flavoring agents, food additives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
JECFA Food Additive: Citric Acid
GSFA Codex: Citric acid (330)
FDA Mainterm (SATF):77-92-9 ; CITRIC ACID
FDA Regulation:
FDA PART 131 -- MILK AND CREAM
Subpart B--Requirements for Specific Standardized Milk and Cream
Sec. 131.111 Acidified milk.


FDA PART 131 -- MILK AND CREAM
Subpart B--Requirements for Specific Standardized Milk and Cream
Sec. 131.112 Cultured milk.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.123 Cold-pack and club cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.124 Cold-pack cheese food.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.129 Dry curd cottage cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.169 Pasteurized process cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.173 Pasteurized process cheese food.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.178 Pasteurized neufchatel cheese spread with other foods.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.179 Pasteurized process cheese spread.


FDA PART 145 -- CANNED FRUITS
Subpart B--Requirements for Specific Standardized Canned Fruits
Sec. 145.134 Canned preserved figs.


FDA PART 145 -- CANNED FRUITS
Subpart B--Requirements for Specific Standardized Canned Fruits
Sec. 145.145 Canned grapefruit.


FDA PART 146 -- CANNED FRUIT JUICES
Subpart B--Requirements for Specific Standardized Canned Fruit Juices and Beverages
Sec. 146.187 Canned prune juice.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.141 Artificially sweetened fruit jelly.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.161 Artificially sweetened fruit preserves and jams.


FDA PART 155 -- CANNED VEGETABLES
Subpart B--Requirements for Specific Standardized Canned Vegetables
Sec. 155.130 Canned corn.


FDA PART 161 -- FISH AND SHELLFISH
Subpart B--Requirements for Specific Standardized Fish and Shellfish
Sec. 161.190 Canned tuna.


FDA PART 163 -- CACAO PRODUCTS
Subpart B--Requirements for Specific Standardized Cacao Products
Sec. 163.110 Cacao nibs.


FDA PART 163 -- CACAO PRODUCTS
Subpart B--Requirements for Specific Standardized Cacao Products
Sec. 163.110 Cacao nibs.


FDA PART 163 -- CACAO PRODUCTS
Subpart B--Requirements for Specific Standardized Cacao Products
Sec. 163.112 Breakfast cocoa.


FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS
Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings
Sec. 169.115 French dressing.


FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS
Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings
Sec. 169.140 Mayonnaise.


FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS
Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings
Sec. 169.150 Salad dressing.


FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart H--Other Specific Usage Additives
Sec. 172.755 Stearyl monoglyceridyl citrate.


FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart I--Multipurpose Additives
Sec. 172.861 Cocoa butter substitute from coconut oil, palm kernel oil, or both oils.


FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart B--Enzyme Preparations and Microorganisms
Sec. 173.160 Candida guilliermondii.


FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart B--Enzyme Preparations and Microorganisms
Sec. 173.165 Candida lipolytica.


FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart C--Solvents, Lubricants, Release Agents and Related Substances
Sec. 173.280 Solvent extraction process for citric acid.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart B--Substances Utilized To Control the Growth of Microorganisms
Sec. 178.1010 Sanitizing solutions.


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1033 Citric acid.


FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION
Subpart A--Foods
Sec. 73.85 Caramel.
 
Physical Properties:
Appearance:white powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 558.50 °C. @ 760.00 mm Hg (est)
Flash Point: 557.00 °F. TCC ( 291.60 °C. ) (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
chelating agents
fragrance
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Citric acid monohydrate 98%
Anhui Haibei
Citric acid monohydrate food grade
BBFY Industrial
Citric Acid Monohydrate
BOC Sciences
For experimental / research use only.
Citric acid monohydrate >98%
Odor: characteristic
Use: Source from dark plum.
Charkit Chemical
CITRIC ACID MONOHYDRATE USP
Charkit Chemical
CITRIC ACID MONOHYDRATE, BP93
ECSA Chemicals
CITRIC ACID MONOHYDRATE BP
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
ECSA Chemicals
CITRIC ACID MONOHYDRATE ex EU
EMD Millipore
For experimental / research use only.
Citric Acid Monohydrate
Foodchem International
Citric Acid Monohydrate
George Uhe Company
Citric Acid Monohydrate
Glentham Life Sciences
Citric acid monohydrate, Ultrapure
Glentham Life Sciences
Citric acid monohydrate
Indis NV
For experimental / research use only.
Citric Acid Monohydrate
Jungbunzlauer Suisse
Citric Acid Monohydrate
Lluch Essence
CITRIC ACID MONOHYDRATED
OQEMA
Citric Acid (Anhydrous, Monohydrate, Coarse, Medium, Fine)
Penta International
CITRIC ACID MONOHYDRATE GRANULAR
Penta International
CITRIC ACID MONOHYDRATE POWDER
Qingdao Dacon Trading
Citric Acid Monohydrate
Santa Cruz Biotechnology
For experimental / research use only.
Citric Acid Monohydrate ≥98%
Shiva Chemicals and Pharmaceuticals
Citric Acid Monohydrate
Sigma-Aldrich
For experimental / research use only.
Citric acid monohydrate ACS reagent, ≥99.0%
SysKem Chemie
Citric Acid Monohydrate
Tianjin Talent Chemical
Citric Acid Monohydrate
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-rat LD50 375 mg/kg
National Technical Information Service. Vol. AD-A121-876

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavoring agents, food additives
Recommendation for citric acid monohydrate usage levels up to:
 not for fragrance use.
 
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
Daily Med:search
NIOSH International Chemical Safety Cards:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :22230
National Institute of Allergy and Infectious Diseases:Data
2-hydroxypropane-1,2,3-tricarboxylic acid;hydrate
Chemidplus:0005949291
RTECS:5949-29-1
 
References:
 2-hydroxypropane-1,2,3-tricarboxylic acid;hydrate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):22230
Pubchem (sid):134987918
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C12649
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2918.14.0000
FDA Listing of Food Additive Status:View
ChemSpider:View
FAO:CITRIC ACID
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 citric acid hydrate
 citric acid, monohydrate
2-hydroxypropane-1,2,3-tricarboxylic acid hydrate
2-hydroxypropane-1,2,3-tricarboxylic acid, hydrate
2-hydroxypropane-1,2,3-tricarboxylic acid;hydrate
1,2,3-propane tricarboxylic acid
1,2,3-propanetricarboxylic acid, 2-hydroxy-, monohydrate
 

Articles:

PubMed:Effect of plasticiser type on the hot melt extrusion of venlafaxine hydrochloride.
PubMed:[Effect of excipients on the preparation and properties of antibiotic solution for intravenous application].
PubMed:A comparative evaluation of fluoridated and non-fluoridated mouthrinses using a 5-day cycling enamel erosion model.
PubMed:Influence of copigmentation on stability of anthocyanins from purple potato peel in both liquid state and solid state.
PubMed:Properties of melt extruded enteric matrix pellets.
PubMed:Critical evaluation of sequential leaching procedures for the determination of Ni and Mn species in welding fumes.
PubMed:Reaction between drug substances and pharmaceutical excipients: formation of citric acid esters and amides of carvedilol in the solid state.
PubMed:Citric acid monohydrate as a release-modifying agent in melt extruded matrix tablets.
PubMed:Formation of interconnected macropores in apatitic calcium phosphate bone cement with the use of an effervescent additive.
PubMed:Investigation of an effervescent additive as porogenic agent for bone cement macroporosity.
PubMed:Synthesis and structure characterization of chromium oxide prepared by solid thermal decomposition reaction.
PubMed:[Determination of trace cobalt in water samples by graphite furnace atomic absorption spectrometry after cloud point].
PubMed:Properties of hot-melt extruded tablet formulations for the colonic delivery of 5-aminosalicylic acid.
PubMed:Experimental designed optimisation and stability evaluation of dry suspensions with artemisinin derivatives for paediatric use.
PubMed:Pilot randomized double-blind trial of treatment of Mycobacterium ulcerans disease (Buruli ulcer) with topical nitrogen oxides.
PubMed:Citric acid production by selected mutants of Aspergillus niger from cane molasses.
PubMed:The utility of alizarin red s staining in calcium pyrophosphate dihydrate crystal deposition disease.
PubMed:Development of a lyophilized parenteral pharmaceutical formulation of the investigational polypeptide marine anticancer agent kahalalide F.
PubMed:An oral sodium citrate-citric acid non-particulate buffer in humans.
PubMed:Comparative analysis of the nuclear proliferative index (Ki-67) in benign prostate, prostatic intraepithelial neoplasia, and prostatic carcinoma.
PubMed:A sensitive bioassay for teicoplanin in serum in the presence or absence of other antibiotics.
PubMed:Lipid deficient extender for bovine spermatozoa: its development and use in measuring freezing-induced lipid loss.
PubMed:[Studies On Phosphatase Activity In Some Parasitic Helminths]
 
Notes:
None found
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