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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Refractive Index: | 1.47800 @ 20.00 °C.
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| Flash Point: | 144.00 °F. TCC ( 62.22 °C. )
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| Soluble in: |
| | water, 0.002364 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for cis-8,11,14-eicosatrienoic acid usage levels up to: | | | not for fragrance use.
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| Recommendation for cis-8,11,14-eicosatrienoic acid flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | dihomo-gamma-linolenic acid | | (Z)-8,11,14- | eicosatrienoic acid | | (Z,Z,Z)-8,11,14- | eicosatrienoic acid | | 8,11-14- | eicosatrienoic acid, (Z,Z,Z)- | | (8Z,11Z,14Z)- | icosa-8,11,14-trienoic acid |
Articles:
| PubMed:Chemical Analysis of Astragali Complanati Semen and Its Hypocholesterolemic Effect Using Serum Metabolomics Based on Gas Chromatography-Mass Spectrometry. |
| PubMed:The role of a FADS1 polymorphism in the association of fatty acid blood levels, BMI and blood pressure in young children-Analyses based on path models. |
| PubMed:Genetic Variants in the ELOVL5 but not ELOVL2 Gene Associated with Polyunsaturated Fatty Acids in Han Chinese Breast Milk. |
| PubMed:Consumption of Red Meat, but Not Cooking Oils High in Polyunsaturated Fat, Is Associated with Higher Arachidonic Acid Status in Singapore Chinese Adults. |
| PubMed:Plasma phospholipids fatty acids, dietary fatty acids, and breast cancer risk. |
| PubMed:Data on the phospholipid fatty acyl composition of retroperitoneal white adipose tissue in ad libitum fed and fasted mice. |
| PubMed:Influence of weight reduction on blood levels of C-reactive protein, tumor necrosis factor-α, interleukin-6, and oxylipins in obese subjects. |
| PubMed:Metabolic engineering of long chain-polyunsaturated fatty acid biosynthetic pathway in oleaginous fungus for dihomo-gamma linolenic acid production. |
| PubMed:Omega 6 fatty acids for the primary prevention of cardiovascular disease. |
| PubMed:Relationship between polyunsaturated fatty acid levels in maternal diets and human milk in the first month post-partum. |
| PubMed:Plasma nutrient biomarkers are associated with waist-to-height ratio in youth with type 1 diabetes. |
| PubMed:Associations between estimated desaturase activity and insulin resistance in korean boys. |
| PubMed:Serum phospholipid monounsaturated fatty acid composition and Δ-9-desaturase activity are associated with early alteration of fasting glycemic status. |
| PubMed:Dietary zinc deficiency affects blood linoleic acid: dihomo-γ-linolenic acid (LA:DGLA) ratio; a sensitive physiological marker of zinc status in vivo (Gallus gallus). |
| PubMed:Immunomodulatory and therapeutic effects of Hot-nature diet and co-supplemented hemp seed, evening primrose oils intervention in multiple sclerosis patients. |
| PubMed:Variation in the FADS1/2 gene cluster alters plasma n-6 PUFA and is weakly associated with hsCRP levels in healthy young adults. |
| PubMed:Altered heart and kidney phospholipid fatty acid composition are associated with cardiac hypertrophy in hypertensive rats. |
| PubMed:Randomized placebo-controlled intervention with n-3 LC-PUFA-supplemented yoghurt: effects on circulating eicosanoids and cardiovascular risk factors. |
| PubMed:Soy milk suppresses cholesterol-induced inflammatory gene expression and improves the fatty acid profile in the skin of SD rats. |
| PubMed:Plasma phospholipid fatty acid composition and estimated desaturase activity in heart failure patients with metabolic syndrome. |
| PubMed:Interrelated effects of dihomo-γ-linolenic and arachidonic acids, and sesamin on hepatic fatty acid synthesis and oxidation in rats. |
| PubMed:Altered plasma and erythrocyte phospholipid fatty acid profile in elite female water polo and football players. |
| PubMed:Eicosadienoic acid differentially modulates production of pro-inflammatory modulators in murine macrophages. |
| PubMed:Fatty acid desaturase (FADS) gene polymorphisms and insulin resistance in association with serum phospholipid polyunsaturated fatty acid composition in healthy Korean men: cross-sectional study. |
| PubMed:Serum cytokeratin 18 M30 antigen level and its correlation with nutritional parameters in middle-aged Japanese males with nonalcoholic fatty liver disease (NAFLD). |
| PubMed:Evaluation of the effect of dietary virgin olive oil on blood pressure and lipid composition of serum and low-density lipoprotein in elderly type 2 diabetic subjects. |
| PubMed:Subchronic (13-week) oral toxicity study of dihomo-gamma-linolenic acid (DGLA) oil in rats. |
| PubMed:Metabolism of omega-6 polyunsaturated fatty acids in women with dysmenorrhea. |
| PubMed:Distribution and metabolism of dihomo-gamma-linolenic acid (DGLA, 20:3n-6) by oral supplementation in rats. |
| PubMed:Fatty acid composition of erythrocyte phospholipids is related to insulin levels, secretion and resistance in obese type 2 diabetics on Metformin. |
| PubMed:Effect of long-term dietary supplementation of high-gamma-linolenic canola oil versus borage oil on growth, hematology, serum biochemistry, and N-6 fatty acid metabolism in rats. |
| PubMed:Effects of sesamin and capsaicin on the mRNA expressions of delta6 and delta5 desaturases in rat primary cultured hepatocytes. |
| PubMed:Fatty acid levels and risk of asthma in young adults. |
| PubMed:Effect of different types of feeding on fatty acid composition of erythrocyte membrane lipids in full-term infants. |
| PubMed:Dietary gamma-linolenic acid dose-dependently modifies fatty acid composition and immune parameters in rats. |
| PubMed:Competitive incorporation of arachidonic acid analogs by cultured rat keratinocytes. |
| PubMed:Interactions of Dietary Fats and Proteins on Fatty Acid Composition of Immune Cells and LTB4 Production by Peritoneal Exudate Cells of Rats. |
| PubMed:The effect of the addition of oil preparation with increased content of n-3 fatty acids on serum lipid profile and clinical condition of cats with miliary dermatitis. |
| PubMed:Evidence for age-related differences in the fatty acid composition of human adipose tissue, independent of diet. |
| PubMed:Dietary supplementation with gamma-linolenic acid alters fatty acid content and eicosanoid production in healthy humans. |
| PubMed:Effects of growth temperature on the fatty acid composition of the free-living nematode Caenorhabditis elegans. |
| PubMed:Effect of age and extent of dietary restriction on hepatic microsomal lipid peroxidation potential in mice. |
| PubMed:Borage or primrose oil added to standardized diets are equivalent sources for gamma-linolenic acid in rats. |
| PubMed:Effects of oral sunflower oil and olive oil on serum and cutaneous fatty acid concentrations in dogs. |
| PubMed:Fatty acid composition of serum phospholipids in an elderly institutionalized Japanese population. |
| PubMed:Lipid malnutrition of patients with liver cirrhosis: effect of low intake of dietary lipid on plasma fatty acid composition. |
| PubMed:Plasma fatty acid composition of breast-feeding Sudanese women. |
| PubMed:Vitamin E intake affects serum thromboxane and tissue essential fatty acid composition in the rat. |
| PubMed:Influence of reduced food intake on polyunsaturated fatty acid metabolism in zinc-deficient rats. |
| PubMed:The effect of dihomo-gamma-linolenic acid (20: 3,n-6) on the composition of phospholipid fatty acids in the liver of rats deficient in essential fatty acids. |
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3D/inchi