EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

chitosan

Supplier Sponsors

Name:methylN-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-
CAS Number: 9012-76-4Picture of molecule3D/inchi
Other(deleted CASRN):191045-06-4
FDA UNII: 82LKS4QV2Y
MDL:MFCD00161512
XlogP3-AA:-21.40 (est)
Molecular Weight:1526.46871000
Formula:C56 H103 N9 O39
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:food additive and cosmetic agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 443 Shrimp-derived chitosan View - notice PDF
GRN 397 Chitosan from Aspergillus niger View - notice PDF
GRN 73 Shrimp-derived chitosan View - notice PDF
GRN 170 Shrimp-derived chitosan View - notice PDF
FEMA Number:4946
FDA:No longer provide for the use of these seven synthetic flavoring substances
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w):-11.706 (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: film formers
hair fixing agents
 
Suppliers:
Achiewell
For experimental / research use only.
Chitosan
AIDP
Chitosan 90% 0.25g/cc
AIDP
Chitosan HD 0.60 g/cc
BOC Sciences
For experimental / research use only.
Chitosan
Carbosynth
For experimental / research use only.
Chitosan
Charkit Chemical
CHITOSAN 90% HIGH DENSITY
Connect Chemicals
Chitosan
Odor: characteristic
Use: Chitosan is a linear polysaccharide composed of randomly distributed β-(1-4)-linked D-glucosamine and N-acetyl-D-glucosamine. It is produced by basic (caustic soda) deacetylation reaction of chitin, the main component of fungi cell walls and insect or crustacean exoskeletons. Chitin is the second most abundant polymer in the biosphere (after cellulose), with app. 10 gigatons of chition being synthesized every year.
ECSA Chemicals
CHITOSAN MUSHROOM
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
Glentham Life Sciences
Chitosan (10 - 120 cps), from Aspergillus niger
Glentham Life Sciences
Chitosan (10 - 120 cps), fungal origin
Glentham Life Sciences
Chitosan (10 cps), very low molecular weight
Glentham Life Sciences
Chitosan (100 - 300 cps), low molecular weight
Glentham Life Sciences
Chitosan (1000 - 2000 cps), high molecular weight
Glentham Life Sciences
Chitosan (2000 - 3500 cps), very high molecular weight
Glentham Life Sciences
Chitosan (30 - 100 cps), low molecular weight
Glentham Life Sciences
Chitosan (300 - 1000 cps), medium molecular weight
Glentham Life Sciences
Chitosan (5 cps), ultra low molecular weight
Glentham Life Sciences
Chitosan, from squid
Glentham Life Sciences
Chitosan, low molecular weight
Glentham Life Sciences
Chitosan
ICHIMARU PHARCOS
Crab (chitin and chitosan)
Odor: characteristic
Use: These substances are derived from the exoskeletons of crabs, shrimp, and other crustaceans, and ICHIMARU PHARCOS was the first to apply carboxymethyl chitin and hydroxypropyl chitosan to skin- and hair-care products.
Maypro Industries
Chitosan
Santa Cruz Biotechnology
For experimental / research use only.
Chitosan ≥75%
Sarchem Laboratories
For experimental / research use only.
Chitosan – Aspergillus Niger MW: 300,000
Sarchem Laboratories
For experimental / research use only.
Chitosan – Crab Shell Source, MW: 100,000-300,000
Sarchem Laboratories
For experimental / research use only.
Chitosan – Crab Shell Source, MW: 500000
Shaanxi Y-Herb Biotechnology
Bulk Water Soluble Chitosan Powder Chitosan Oligosaccharide High Molecular Weight
Sigma-Aldrich: Aldrich
For experimental / research use only.
Chitosan, low molecular weight
Synerzine
Chitosan
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
food additive and cosmetic agents
Recommendation for chitosan usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 30
Click here to view publication 30
 average usual ppmaverage maximum ppm
baked goods: 1500.000002000.00000
beverages(nonalcoholic): 1500.000002000.00000
beverages(alcoholic): 1500.000002000.00000
breakfast cereal: --
cheese: 1500.000002000.00000
chewing gum: 1500.000002000.00000
condiments / relishes: 1500.000002000.00000
confectionery froastings: 1500.000002000.00000
egg products: --
fats / oils: 1500.000002000.00000
fish products: 1500.000002000.00000
frozen dairy: --
fruit ices: --
gelatins / puddings: 1500.000002000.00000
granulated sugar: --
gravies: 1500.000002000.00000
hard candy: --
imitation dairy: 1500.000002000.00000
instant coffee / tea: 1500.000002000.00000
jams / jellies: 1500.000002000.00000
meat products: 1500.000002000.00000
milk products: 1500.000002000.00000
nut products: --
other grains: 1500.000002000.00000
poultry: --
processed fruits: 1500.000002000.00000
processed vegetables: 1500.000002000.00000
reconstituted vegetables: 1500.000002000.00000
seasonings / flavors: 1500.000002000.00000
snack foods: --
soft candy: 1500.000002000.00000
soups: 1500.000002000.00000
sugar substitutes: 1500.000002000.00000
sweet sauces: 1500.000002000.00000
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf

ClinicalTrials.gov:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):9012-76-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :71853
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:nwg
methylN-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-
Chemidplus:0009012764
 
References:
 methylN-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):71853
Pubchem (sid):135029387
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
KEGG (GenomeNet):C00734
HMDB (The Human Metabolome Database):HMDB03404
FooDB:FDB015634
Export Tariff Code:3913.90.2050
FDA Listing of Food Additive Status:View
MedlinePlusSupp:View
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 biological additives
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
2-amino-2-deoxy-poly-D-glucosamine
 chitopearl
 chitopearl 3510
shrimp-derived chitosan
 chitosan from aspergillus niger
 chitosan, from shrimp
 flonac C
 poliglusam
 

Articles:

PubMed:Encapsulation of liquid smoke flavoring in ca-alginate and ca-alginate-chitosan beads.
J-Stage:MAP Kinases, MPK9 and MPK12, Regulate Chitosan-Induced Stomatal Closure
PubMed:Self-destructing "mothership" capsules for timed release of encapsulated contents.
PubMed:Lipid oxidative changes in chitosan-oregano coated traditional dry fermented sausage Petrovská klobása.
PubMed:Development of novel guava puree films containing chitosan nanoparticles.
PubMed:Reducing SOâ‚‚ in fresh pork burgers by adding chitosan.
PubMed:Stability of citral in emulsions coated with cationic biopolymer layers.
PubMed:Chitosan coating improves retention and redispersibility of freeze-dried flavor oil emulsions.
PubMed:Evolution of selected volatiles in chitosan-coated strawberries ( Fragaria x ananassa ) during refrigerated storage.
PubMed:Review of methods for the reduction of dietary content and toxicity of acrylamide.
PubMed:Chemical and physical stability of citral and limonene in sodium dodecyl sulfate-chitosan and gum arabic-stabilized oil-in-water emulsions.
PubMed:Quality properties of pork sausage prepared with water-soluble chitosan oligomer.
 
Notes:
deacetylated chitin, a linear polysaccharide of deacetylated beta-1,4-d-glucosamine. it is used in hydrogel and to treat wounds. Obt. from Chitin BVM67-G by methods incl. alkaline hydrol. and thermochemical-chemical treatment. Used in edible coatings for fruit and vegetables and in biodegradable packaging films. Chitosan (pronounced /?ka?t?sæn/) is a linear polysaccharide composed of randomly distributed ?-(1-4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine (acetylated unit). It has a number of commercial and possible biomedical uses.; Chitosan can also be used in water processing engineering as a part of a filtration process. Chitosan causes the fine sediment particles to bind together and is subsequently removed with the sediment during sand filtration. Chitosan also removes phosphorus, heavy minerals, and oils from the water. Chitosan is an important additive in the filtration process. Sand filtration apparently can remove up to 50% of the turbidity alone while the chitosan with sand filtration removes up to 99% turbidity. Chitosan has been used to precipitate caseins from bovine milk and cheese making; Chitosan has a rich history of being researched for applications in agriculture and horticulture dating back to the 1980s. By 1989 Bentech Labs patented chitosan salt solutions applied to crops for improved freeze protection or to crop seed for seed priming. Shortly thereafter Bentech's chitosan salt received the first ever biopesticide label from the EPA. Numerous other chitosan patents for plants soon followed. Chitosan applications to protect plants have been used in space as well. NASA first flew a chitosan experiment to protect adzuki beans grown aboard the space shuttle and Mir space station in 1997 (see photo left). NASA results revealed chitosan induces increased growth (biomass) and pathogen resistance due to elevated levels of beta 1-3 glucanase enzymes within plant cells. NASA confirmed chitosan elicits the same effect in plants on earth. Over 20 years of R&D by DuPont/ConAgra Ventures (DCV) and AgriHouse Inc have gone into developing non-toxic low molecular weight chitosan polymer solutions safe enough for broad spectrum agricultural and horticultural use. In 2008, AgriHouse Inc, Denver [Berthoud], Colorado, was granted EPA natural broad spectrum elicitor status for YEA!® Yield Enhancing Agent, a liquid solution containing an ultra low molecular active ingredient of 0.25% chitosan. YEA! is a next generation natural chitosan elicitor solution for agriculture and horticultural and was granted an amended label for foliar and irrigation applications by the EPA in June, 2009. A milliliter of YEA! contains over 14.4 X 10¹³ bio-active low molecular weight chitosan molecules and it is 600 times more effective than common chitosan). Given its low potential for toxicity and its abundance in the natural environment, chitosan does not harm people, pets, wildlife, or the environment when used according to label directions. Agricultural chitosan facts are located on USDA and EPA web sites.; Deacetylated CHITIN, a linear polysaccharide of deacetylated beta-1,4-D-glucosamine. It is used in HYDROGEL and to treat WOUNDS.; Chitosan can also be used in water processing engineering as a part of a filtration process. Chitosan causes the fine sediment particles to bind together and is subsequently removed with the sediment during sand filtration. Chitosan also removes phosphorous, heavy minerals, and oils from the water. Chitosan is an important additive in the filtration process. Sand filtration apparently can remove up to 50% of the turbidity alone while the Chitosan with sand filtration removes up to 99% turbidity.; Chitosan is a linear polysaccharide composed of randomly distributed beta(1->4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine (acetylated unit). It has a number of commercial amd possible biomedical uses.; In agriculture, chitosan is used primarily as a natural seed treatment and plant growth enhancer, and as a substance that boosts the ability of plants to defend against fungal infections. The natural biocontrol active ingredient, chitin/chitosan, are found in the shells of crustaceans, such as lobsters, crabs, and shrimp, and many other organisms including insects and fungi. It is one of the most abundant bio-gradable materials in the world. Degraded molecules of chitin/chitosan exist in soil and water. Chitosan applications for plants and crops are regulated by the EPA and the USDA National Organic Program regulates its use on organic certified farms and crops. It is approved for use outdoors and indoors on plants and crops grown commercially and by consumers. The natural biocontrol ability of chitosan should not be confused with the effects of fertilizers or pesticides upon plants or the environment. It represents a new tier of cost effective biological control of crops.
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