calcium phosphate monobasic
phosphoric acid, calcium salt (2:1)
 
Notes:
mw 234.05. Added to flour as a nutrient source and leavening agent; stabiliser and thickener for fruit jellies, preserves and jams; also used in foods as pH control agent, firming agent, sequestrant and dietary supplement
  • American International Chemical, LLC.
    • American International Chemical, Inc.
      Consistent sources
      North American supplier for globally sourced ingredients.
      AIC is a Framingham, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of 30 Sales Representatives, along with our 19 strategically located warehouses are ready to supply product when and where you need it.
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      Product(s):
      122699 Monocalcium Phosphate
       
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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      Product(s):
      MONOCALCIUM PHOSPHATE, MONO HYDRATE, FCC POWDER
       
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calcium dihydrogen phosphate (Click)
CAS Number: 7758-23-8Picture of molecule
ECHA EINECS - REACH Pre-Reg: 231-837-1
FDA UNII: 701EKV9RMN
MDL: MFCD00149602
Molecular Weight: 234.05100400
Formula: Ca H4 O8 P2
NMR Predictor: Predict (works with chrome or firefox)
Category: buffering, firming, sequestrant, leavening, dough conditioner, texturizer, yeast food, nutrient, acidity regulators
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
1975 Calcium phosphate monobasic View-review
EU SANCO Calcium phosphates View-review
JECFA Food Additive: Calcium Dihydrogen Phosphate
GSFA Codex: Monocalcium dihydrogen phosphate (341(i))
FDA Mainterm: CALCIUM PHOSPHATE, MONOBASIC
FDA Regulation:
FDA PART 136 -- BAKERY PRODUCTS
Subpart B--Requirements for Specific Standardized Bakery Products
Sec. 136.110 Bread, rolls, and buns.


FDA PART 136 -- BAKERY PRODUCTS
Subpart B--Requirements for Specific Standardized Bakery Products
Sec. 136.115 Enriched bread, rolls, and buns.


FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.165 Enriched flour.


FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.175 Phosphated flour.


FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.180 Self-rising flour.


FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.270 Self-rising white corn meal.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.141 Artificially sweetened fruit jelly.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.161 Artificially sweetened fruit preserves and jams.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart B--Multiple Purpose GRAS Food Substances
Sec. 182.1217 Calcium phosphate.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart G--Sequestrants1
Sec. 182.6215 Monobasic calcium phosphate.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart I--Nutrients
Sec. 182.8217 Calcium phosphate.
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Physical Properties:
Appearance: white crystalline granules (est)
Food Chemicals Codex Listed: No
Boiling Point: 157.00 to  158.00 °C. @ 760.00 mm Hg
Vapor Pressure: 1.410000 mm/Hg @ 25.00 °C. (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -2.148 (est)
Soluble in:
 water, slightly
 water, 1e+006 mg/L @ 25 °C (est)
Insoluble in:
 alcohol
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: buffering agents
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Suppliers:
American International Chemical, LLC.
Monocalcium Phosphate
Charkit Chemical
MONOCALCIUM PHOSPHATE, MONO HYDRATE, FCC POWDER
Foodchem International
Monocalcium Phosphate
Graham Chemical
MonoCalcium Phosphate
Kraft Chemical
Monocalcium Phosphate
Lianyungang Yunbo Chemical
MONOCALCIUM PHOSPHATE
Prinova
Monocalcium Phosphate
Qingdao Dacon Trading
Monocalcium Phosphate
Santa Cruz Biotechnology
For experimental / research use only.
Calcium dihydrogenphosphate
Sigma-Aldrich
For experimental / research use only.
Calcium phosphate monobasic monohydrate purum p.a., ≥85% (KT)
Zhong Ya Chemical
Calcium Phosphate, Mono
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Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 22 - Do not breath dust.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  3986 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE SKIN AND APPENDAGES (SKIN): HAIR: OTHER
National Technical Information Service. Vol. OTS0571950

oral-mouse LD50  15250 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 52(12), Pg. 87, 1987.

Dermal Toxicity:
skin-rabbit LD50 > 2000 mg/kg
SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
National Technical Information Service. Vol. OTS0571950

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: buffering, firming, sequestrant, leavening, dough conditioner, texturizer, yeast food, nutrient, acidity regulators
Recommendation for calcium phosphate monobasic usage levels up to:
 not for fragrance use.
 
Recommendation for calcium phosphate monobasic flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Assessment of one published review on health risks associated with phosphate additives in food
View page or View pdf
EPI System: View
NLM Hazardous Substances Data Bank: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 7758-23-8
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 24454
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 calcium dihydrogen phosphate
Chemidplus: 0007758238
RTECS: TB8527000 for cas# 7758-23-8
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References:
 calcium dihydrogen phosphate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 7758-23-8
Pubchem (cid): 24454
Pubchem (sid): 134989991
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
CHEBI: View
KEGG (GenomeNet): C13556
HMDB (The Human Metabolome Database): Search
FooDB: FDB013367
Export Tariff Code: 2835.26.0000
Haz-Map: View
Household Products: Search
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Formulations/Preparations:
•superphosphate obtained from sulfuric acid treatment is about 30% calcium superphosphate, 10% dicalcium orthophosphate, 45% calcium sulfate, 10% iron oxide, silica, alumina et cetera, & 5% water contains 18-21% avail phosphorus pentoxide. triple superphosphate from phosphoric acid treatment contains from 43-50% avail phosphorus pentoxide. •grade: fcc food chemicals codex, ceramic, anhydrous, hydrated
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 abrasives 
 buffering agents 
 oral care agents 
 viscosity controlling agents 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 acid calcium phosphate
 calcium biphosphate
 calcium bis(dihydrogen phosphate)
 calcium bis(dihydrogenphosphate)
 calcium dihydrogen phosphate
 calcium dihydrogenphoshate
 calcium dihydrogenphosphate
 calcium hydrogen phosphate (Ca(H2PO4)2)
 calcium monobasic phosphate
monocalcium orthophosphate
monocalcium phosphate
 calcium phosphate monobasic
 calcium phosphate, monobasic
monocalcium phosphate, monobasic
 calcium tetrahydrogen diphosphate
 calciumdihydrogenorthophosphate
 calciumphosphatemonobasic
 phosphoric acid, calcium salt (2:1)
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Articles:
PubMed: Effect of bolus and divided feeding on urine ions and supersaturation in genetic hypercalciuric stone-forming rats.
PubMed: Antioxidant mechanism of milk mineral-high-affinity iron binding.
PubMed: Crystalline calcium phosphate and magnetic mineral content of Daphnia resting eggs.
PubMed: The use of sedimentation field flow fractionation and photon correlation spectroscopy in the characterization of casein micelles.
PubMed: Impaired rennetability of heated milk; study of enzymatic hydrolysis and gelation kinetics.
PubMed: Acute effect of high-calcium milk with or without additional magnesium, or calcium phosphate on parathyroid hormone and biochemical markers of bone resorption.
PubMed: Removal of phosphate by seafood processing wasted sludge.
PubMed: Dietary calcium phosphate promotes Listeria monocytogenes colonization and translocation in rats fed diets containing corn oil but not milk fat.
PubMed: Fine and ultrafine particles of the diet: influence on the mucosal immune response and association with Crohn's disease.
PubMed: Comparative anticaries efficacy of sodium fluoride and sodium monofluorophosphate dentifrices. A two-year caries clinical trial on children in New Jersey and Puerto Rico.
PubMed: Comparison of urine composition of healthy Labrador retrievers and miniature schnauzers.
PubMed: Red meat and colon cancer: dietary haem-induced colonic cytotoxicity and epithelial hyperproliferation are inhibited by calcium.
PubMed: The enhanced anticaries efficacy of a sodium fluoride and dicalcium phosphate dihydrate dentifrice in a dual-chambered tube. A 2-year caries clinical study on children in Brazil.
PubMed: The enhanced anticaries efficacy of a sodium fluoride and dicalcium phosphate dihydrate dentifrice in a dual-chambered tube. A 2-year caries clinical study on children in the United States of America.
PubMed: Utilisation of different phosphorus sources in relation to their fluorine content for broilers and layers.
PubMed: Radionuclide fluxes at a plant manufacturing dicalcium phosphate for domestic animals.
PubMed: Effect of beta-lactoglobulin and precipitation of calcium phosphate on the thermal coagulation of milk.
PubMed: Bioavailability of the calcium in fortified soy imitation milk, with some observations on method.
PubMed: Dietary calcium phosphate stimulates intestinal lactobacilli and decreases the severity of a salmonella infection in rats.
PubMed: Respiratory distress and sudden death associated with receipt of a peripheral parenteral nutrition admixture.
PubMed: A quantitative model for prediction of iron bioavailability from Indian meals: an experimental study.
PubMed: Use of total nutrient admixtures should not be limited.
PubMed: Urinary oxalate excretion in premature infants: effect of human milk versus formula feeding.
PubMed: Caring about stability and compatibility.
PubMed: Laying hens respond differently to high dietary levels of phosphorus in monobasic and dibasic calcium phosphate.
PubMed: Bioceramic implantation in the intermandibular space in bilateral rostral mandibulectomy of the dog.
PubMed: Solubility of calcium salts and carrageenan used in infant formulas did not influence calcium absorption in rats.
PubMed: Regulation of G418 selection efficiency by cell-cell interaction in transfection.
PubMed: Calcium supplementation: effect on iron absorption.
PubMed: Protein and fat utilization by humans as affected by calcium phosphate, calcium carbonate, and manganese gluconate supplements.
PubMed: Measurement of dietary and dentifrice effects upon calculus accumulation rates in the domestic ferret.
PubMed: Subunit structure of casein micelles from small-angle neutron-scattering.
PubMed: Plaque fluid pH, calcium and phosphorus responses to calcium food additives in a chewable candy.
PubMed: Improvement of the nutritional quality of Egyptian and Sudanese sorghum grains by the addition of phosphates.
PubMed: Chronological variation in chemical composition of urinary calculi between 1965-68 and 1982-86 in north western India.
PubMed: Factors affecting absorbability of calcium from calcium salts and food.
PubMed: The effect of supracrestal tricalcium phosphate ceramic-microfibrillar collagen grafting on postsurgical soft tissue levels.
PubMed: Effect of dietary phosphorus on selenium retention in postweaning swine.
PubMed: Effect of dietary calcium on selenium retention in postweaning swine.
PubMed: Influence of virginiamycin on phosphorus utilization by broiler chicks.
PubMed: Effect of dietary phosphorus level and source on productive performance and egg quality of two commercial strains of laying hens.
PubMed: Bioavailability of phosphorus in commercial phosphate supplements for turkeys.
PubMed: Neonatal intestinal obstruction associated with oral calcium supplementation.
PubMed: Letter: The use of a calcium sucrose phosphates-calcium orthophosphate complex as a cariostatic agent.
PubMed: The use of a calcium sucrose phosphates-calcium orthophosphate complex as a cariostatic agent.
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