calcium hypochlorite
calcium chlorohypochloride
 
Notes:
None found
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calcium;dihypochlorite (Click)
CAS Number: 7778-54-3Picture of molecule
Other: 104381-95-5
ECHA EINECS - REACH Pre-Reg: 231-908-7
FDA UNII: 11DXB629VZ
Nikkaji Web: J148.074J
MDL: MFCD00010900
Molecular Weight: 142.98040000
Formula: Ca Cl2 O2
NMR Predictor: Predict (works with chrome or firefox)
Category: antimicrobial agents
 
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Physical Properties:
Appearance: white granular solid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 2.35000 @  25.00 °C.
Melting Point: 100.00 °C. @ 760.00 mm Hg (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antimicrobial agents
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Suppliers:
Covalent Chemical
Calcium Hypochlorite
Santa Cruz Biotechnology
For experimental / research use only.
Calcium Hypochlorite Technical
Sigma-Aldrich
For experimental / research use only.
Calcium Hypochlorite technical grade
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-man TDLo  143 mg/kg
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: NAUSEA OR VOMITING
Japanese Journal of Toxicology. Vol. 11, Pg. 137, 1998.

oral-rat LD50  850 mg/kg
Pesticide & Toxic Chemical News. Vol. 9, Pg. 21, 1980.

Dermal Toxicity:
skin-rabbit LDLo 2000 mg/kg
GASTROINTESTINAL: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: FOOD INTAKE (ANIMAL)
National Technical Information Service. Vol. OTS0570606

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: antimicrobial agents
Recommendation for calcium hypochlorite usage levels up to:
 not for fragrance use.
 
Recommendation for calcium hypochlorite flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
NIOSH International Chemical Safety Cards: search
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
Cancer Citations: Search
Toxicology Citations: Search
Env. Mutagen Info. Center: Search
EPA Substance Registry Services (TSCA): 7778-54-3
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 24504
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 calcium;dihypochlorite
Chemidplus: 0007778543
EPA/NOAA CAMEO: hazardous materials
RTECS: 7778-54-3
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References:
 calcium;dihypochlorite
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 7778-54-3
Pubchem (cid): 24504
Pubchem (sid): 134990468
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
KEGG (GenomeNet): D01727
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2828.10.0000
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ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Formulations/Preparations:
•grades: commercial (70%); high purity (99.2% available chlorine as calcium hypochlorite). •ingredient of camporit which also contains nacl. •active ingredient in lo-bax, hth, perchloron, pennswim brand products, & in eusol. •chlorinated lime (bleaching powder) consists of mixt of calcium hypochlorite, calcium chloride, & calcium hydroxide; should not be confused with pure calcium hypochlorite. ... •chloride of lime (35% calcium chlorine); highest calcium hypochlorite (70% available chlorine) •chlorinated lime consists of a mixture of calcium chloride and calcium hypochloride and should contain a minimum of 30% available chlorine. •65% available chlorine, 4 oz briquettes grades; granular, tablet grades; 70% granular grades; technical grades •grade: 35-37% active chlorine, technical lime, chlorinated •grade or purity: 70% (self-propagating); 65% (non-propagating) •chemically, it consists of varying proportions of calcium hypochlorite, calcium chloride, calcium oxychloride, calcium chloride, free calcium hydroxides, and water. chlorinated lime •sold as partially hydrated calcium hypochlorite(65% available chlorine), sanitizer (50% available chlorine), and mildew control (32% available chlorine). •solutions of calcium hypochlorite: milk of lime - a suspension of calcium hydroxide in water - is chlorinated.
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 bleaching powder
 calcium chlorohydrochlorite
 calcium chlorohypochloride
 calcium dihypochlorite
 calcium hypochloride
 calcium oxychloride
 calciumhypochlorite
 CCH
 chemichlon G
 chemichlor G
 HTH
 HY-chlor
 LO-bax
 losantin
 pittchlor
 pittcide
 pittclor
 solvox KS
 T-eusol
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Articles:
PubMed: Comparative Evaluation of Calcium Hypochlorite and Sodium Hypochlorite Associated with Passive Ultrasonic Irrigation on Antimicrobial Activity of a Root Canal System Infected with Enterococcus faecalis: An In Vitro Study.
PubMed: Outbreaks caused by sprouts, United States, 1998-2010: lessons learned and solutions needed.
PubMed: Effectiveness of calcium hypochlorite on viral and bacterial contamination of alfalfa seeds.
PubMed: Effectiveness of a novel spontaneous carvacrol nanoemulsion against Salmonella enterica Enteritidis and Escherichia coli O157:H7 on contaminated mung bean and alfalfa seeds.
PubMed: Examination of tapered plastic multimode fiber-based sensor performance with silver coating for different concentrations of calcium hypochlorite by soft computing methodologies--a comparative study.
PubMed: Current intervention strategies for the microbial safety of sprouts.
PubMed: Comparative study of disinfectants for use in low-cost gravity driven household water purifiers.
PubMed: Inactivation of internalized and surface contaminated enteric viruses in green onions.
PubMed: Microbial contamination in sprouts: how effective is seed disinfection treatment?
PubMed: Promising role of calcium hypochlorite as a disinfectant: an in vitro evaluation regarding its effect on type V dental stone.
PubMed: The effects of prolonged oral administration of the disinfectant calcium hypochlorite in Nigerian commercial cockerels.
PubMed: Evaluating the efficiency of lettuce disinfection according to the official protocol in iran.
PubMed: Comparative evaluation of calcium hypochlorite and sodium hypochlorite on soft-tissue dissolution.
PubMed: [Effect of different calcium hypochlorite concentrations on the survival of potentially pathogenic microorganisms isolated from Baikal Lake].
PubMed: Inactivation of salmonella in biofilms and on chicken cages and preharvest poultry by levulinic Acid and sodium dodecyl sulfate.
PubMed: Evaluation of pot-chlorination of wells during a cholera outbreak, Bissau, Guinea-Bissau, 2008.
PubMed: Disinfection aboard cruise liners and naval units: formation of disinfection by-products using chlorine dioxide in different qualities of drinking water.
PubMed: Removal of trichlorobenzene using 'oxygen-enriched' highly active absorbent.
PubMed: Spores of Bacillus cereus strain KBAB4 produced at 10 °C and 30 °C display variations in their properties.
PubMed: Inactivation of Escherichia coli O157:H7 and Salmonella typhimurium DT 104 on alfalfa seeds by levulinic acid and sodium dodecyl sulfate.
PubMed: [A new method for the preparation of potassium ferrate and spectroscopic characterization].
PubMed: Efficacy studies of Reactive Skin Decontamination Lotion, M291 Skin Decontamination Kit, 0.5% bleach, 1% soapy water, and Skin Exposure Reduction Paste Against Chemical Warfare Agents, part 2: guinea pigs challenged with soman.
PubMed: Reduction of Salmonella on alfalfa seeds using peroxyacetic acid and a commercial seed washer is as effective as treatment with 20 000 ppm of Ca(OCl)2.
PubMed: Synergistic effect of chlorine dioxide and drying treatments for inactivating Escherichia coli O157:H7 on radish seeds.
PubMed: Prevalence of parasitic contamination of raw vegetables in villages of Qazvin Province, Iran.
PubMed: Validation of an in situ solidification/stabilization technique for hazardous barium and cyanide waste for safe disposal into a secured landfill.
PubMed: Practical evaluation of Mung bean seed pasteurization method in Japan.
PubMed: Occurrence of bromate, chlorite and chlorate in drinking waters disinfected with hypochlorite reagents. Tracing their origins.
PubMed: Microbiological and physical quality changes in vacuum loader cups associated with the use of various sanitizing compounds.
PubMed: Transcriptome analysis of Escherichia coli O157:H7 exposed to lysates of lettuce leaves.
PubMed: Pool chemical blast injury.
PubMed: Application of lime and calcium hypochlorite in the dephenolisation and discolouration of olive mill wastewater.
PubMed: Performance of an alkalophilic and halotolerant laccase from gamma-proteobacterium JB in the presence of industrial pollutants.
PubMed: Efficacy of detergents and fresh produce disinfectants against microorganisms associated with mixed raw vegetables.
PubMed: Inhalational and dermal injury due to explosion of calcium hypochlorite.
PubMed: Acidified sodium chlorite as an alternative to chlorine for elimination of salmonella on alfalfa seeds.
PubMed: Factors affecting the efficacy of pressure inactivation of Escherichia coli O157:H7 on alfalfa seeds and seed viability.
PubMed: Inactivation of MS2 F(+) coliphage on lettuce by a combination of UV light and hydrogen peroxide.
PubMed: Inactivation of avian influenza virus using common detergents and chemicals.
PubMed: Growth of Salmonella on sprouting alfalfa seeds as affected by the inoculum size, native microbial load and Pseudomonas fluorescens 2-79.
PubMed: A preliminary assessment of Bacillus anthracis spore inactivation using an electrochemically activated solution (ECASOL).
PubMed: Pathogen detection, testing, and control in fresh broccoli sprouts.
PubMed: History of evidence-based medicine. Oranges, chloride of lime and leeches: barriers to teaching old dogs new tricks.
PubMed: Enhanced survival of Salmonella enterica in vesicles released by a soilborne Tetrahymena species.
PubMed: Performance of a household-level arsenic removal system during 4-month deployments in Bangladesh.
PubMed: A facile preparation of uronates via selective oxidation with TEMPO/KBr/Ca(OCl)(2) under aqueous conditions.
PubMed: Efficacy of chlorine and calcinated calcium treatment of alfalfa seeds and sprouts to eliminate Salmonella.
PubMed: Calcium hypochlorite as a disinfecting additive for dental stone.
PubMed: Industry practices and compliance with U.S. Food and Drug Administration guidelines among California sprout firms.
PubMed: Contact sensitivity to calcium hypochlorite.
PubMed: Effect of chlorination of drinking-water on water quality and childhood diarrhoea in a village in Pakistan.
PubMed: Alfalfa sprouts and Salmonella Kottbus infection: a multistate outbreak following inadequate seed disinfection with heat and chlorine.
PubMed: Calcium hypochlorite removal of mercury and petroleum hydrocarbons from co-contaminated soils.
PubMed: Formation of dimer-type ketals in the reaction of 2,4,6-trichlorophenol and 2,4,6-trichloro-m-cresol with calcium hypochlorite in methanol: conversion to quinones and other compounds.
PubMed: Chlorine and chlorine dioxide treatment to reduce or remove EBDCs and ETU residues in a solution.
PubMed: Cross-contamination of lettuce with Escherichia coli O157:H7.
PubMed: Detection and elimination of Salmonella mbandaka from naturally contaminated alfalfa seed by treatment with heat or calcium hypochlorite.
PubMed: Salmonella Typhimurium infections transmitted by chlorine-pretreated clover sprout seeds.
PubMed: Multistate outbreak of Salmonella serovar Muenchen infections associated with alfalfa sprouts grown from seeds pretreated with calcium hypochlorite.
PubMed: Wrinkled alfalfa seeds harbor more aerobic bacteria and are more difficult to sanitize than smooth seeds.
PubMed: [Aluminum hydroxide hydrogel to remove arsenic from water].
PubMed: Postharvest treatments for the reduction of mancozeb in fresh apples.
PubMed: Growth of Salmonella during sprouting of alfalfa seeds associated with salmonellosis outbreaks.
PubMed: Attachment and growth of Salmonella Chester on apple fruits and in vivo response of attached bacteria to sanitizer treatments.
PubMed: Efficacy of novel organic acid and hypochlorite treatments for eliminating Escherichia coli O157:H7 from alfalfa seeds prior to sprouting.
PubMed: Microbiological safety evaluations and recommendations on sprouted seeds. National Advisory Committee on Microbiological Criteria for Foods.
PubMed: Comparison of chemical treatments to eliminate enterohemorrhagic Escherichia coli O157:H7 on alfalfa seeds.
PubMed: Increasing the tolerance of organophosphorus hydrolase to bleach
PubMed: Effect of gamma irradiation on the production of cell wall degrading enzymes by Aspergillus niger.
PubMed: Decontamination of chicken carcasses artificially contaminated with Salmonella.
PubMed: Comparison of chemical treatments to kill Salmonella on alfalfa seeds destined for sprout production.
PubMed: Narrow-mouthed water storage vessels and in situ chlorination in a Bolivian community: a simple method to improve drinking water quality.
PubMed: Inactivation of Brazilian wild type and enterotoxigenic Escherichia coli by chlorine.
PubMed: Rapid toxicity assessment using an in vivo enzyme test for Brachionus plicatilis (Rotifera).
PubMed: Explosion risk from swimming pool chlorinators and review of chlorine toxicity.
PubMed: Hypochlorite solution as a decontaminant in sulfur mustard contaminated skin defects in the euthymic hairless guinea pig.
PubMed: Survival and respiratory activity of genetically engineered Pseudomonas spp. exposed to antimicrobial agents in broth and soil.
PubMed: Formulation of water disinfectant tablets for rural communities in Nigeria.
PubMed: Topical absorption and inactivation of cytotoxic anticancer agents in vitro.
PubMed: Powders, composed of chlorine-releasing agent acrylic resin mixtures or based on peroxygen compounds, for spills of body fluids.
PubMed: Effect of parboiling and bran removal on aflatoxin levels in Sri Lankan rice.
PubMed: Hypochlorite salts.
PubMed: Combined halogen disinfectants in poultry processing.
PubMed: Legionnaires' disease in the work environment: implications for environmental health.
PubMed: Inactivation of Legionella pneumophila by hypochlorite and an organic chloramine.
PubMed: N-chloropiperidine and calcium hypochlorite: possible examples of toxicity-dependent clastogenicity in vitro.
PubMed: Bactericidal properties of an organic N-chloramine formed in situ.
PubMed: Oxidative destruction of hydrazines produces N-nitrosamines and other mutagenic species.
PubMed: Inactivation of thymidylate synthase by chlorine disinfectants.
PubMed: Destruction of cyanogen bromide and inorganic cyanides.
PubMed: Bactericidal properties of a new water disinfectant.
PubMed: Primary mutagenicity screening of food additives currently used in Japan.
PubMed: Protein-enhanced fluorescein chemiluminescence used in an immunoassay for rubella antibody in serum.
PubMed: Laboratory studies of disinfectants against Legionella pneumophila.
PubMed: Effects of halogenated organic compounds on photosynthesis in estuarine phytoplankton.
PubMed: [Electron microscopic study of normal Bacillus anthracoides spores and after exposure to a chloroactive disinfectant].
PubMed: The effect of temperature on cutaneous CO2, loss and conductance in the bullfrog.
PubMed: [Studies on inactivation of viruses in drinking and surface water. A contribution to the decontamination of water by field methods (author's transl)].
PubMed: [Study of the feasibility and conditions for disinfecting materials made of chemical fibers by immersion in solutions of several disinfectants].
PubMed: [Detoxification of staphylococcal-enterotoxin B in water (author's transl)].
PubMed: [Effect of calcium hypochlorite on Bacillus anthracoides spores].
PubMed: [Change in the activity of the enzymatic systems of Bacillus anthracoides spores during germination and under the action of Ca hypochlorite].
PubMed: Chemical disinfection of holding-tank sewage.
PubMed: Calcium hypochlorite for disinfection of hydrotherapy equipment.
PubMed: [Disinfecting action of a solution of calcium hypochlorite on pathogenic serotypes of coliform bacilli].
PubMed: [Control of calcium hypochlorite solutions for disinfection at dairy establishments].
PubMed: [Effect of calcium hypochlorite on Clostridium botulinum type C toxin].
PubMed: Calcium hypochlorite for disinfection of hydrotherapy equipment.
PubMed: [Comparative characteristics of the sporocidal action of gaseous chlorine and calcium hypochlorite in aqueous medium].
PubMed: [Stability of solutions of calcium hypochlorite used for disinfection of equipment, utensils and hands of the workers at food enterprises].
PubMed: [Differences of activity existing between calcium hypochlorite & chloramine T evaluated in function of concentration of the chlorate & pH of the medium].
PubMed: [Differences in the activity of calcium hypochlorite & chloramine T evaluated in relation to the concentration of the chlorinating agent & the pH of the medium].
PubMed: [Effect of lowered surface tension of calcium hypochlorite solution on its microbicide action].
PubMed: [Studies on the disinfective effect of calcium hypochlorite (caporit)].
PubMed: [Colorimetric determination of active chlorine in calcium hypochlorite].
PubMed: [Calcium hypochlorite in control of muscardine in Bombyx mori].
PubMed: [Spraying of refuse with calcium hypochlorite].
PubMed: THE STRUCTURE OF THE COLLODION MEMBRANE AND ITS ELECTRICAL BEHAVIOR : II. THE ACTIVATED COLLODION MEMBRANE.
PubMed: Some Observations on the Germicidal Efficiency of Chloramine-T and Calcium Hypochlorite.
PubMed: RELATIVE IRRITANT PROPERTIES OF THE CHLORINE GROUP OF ANTISEPTICS.
PubMed: Observations on the Types of Organism Isolated from Water after Treatment with Calcium Hypochlorite.
PubMed: SOME RESULTS OF THE TREATMENT OF THE BALTIMORE DRINKING WATER BY CALCIUM HYPOCHLORITE.
PubMed: A STUDY OF CALCIUM HYPOCHLORITE AS A DISINFECTANT OF WATER.
PubMed: THE TREATMENT OF THE BALTIMORE DRINKING WATER BY MEANS OF CALCIUM HYPOCHLORITE.
PubMed: THE STERILIZATION OF MILK BOTTLES WITH CALCIUM HYPOCHLORITE.
PubMed: THE RESISTANCE OF CERTAIN BACTERIA TO CALCIUM HYPOCHLORITE.
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