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calcium chloride dihydrate
calcium chloride hydrate (1:2:2)

Supplier Sponsors

Name:calcium dichloride dihydrate
CAS Number: 10035-04-8Picture of molecule3D/inchi
FDA UNII: M4I0D6VV5M
MDL:MFCD00149613
Molecular Weight:147.01228000
Formula:Ca Cl2 H4 O2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:multipurpose additives, firming agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1193 Calcium chloride View - review
EU SANCO Calcium chloride View - review
GRN 785 Calcium chloride View - notice PDF
FDA Mainterm (SATF):10035-04-8 ; CALCIUM CHLORIDE
FDA Regulation:
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.102 Asiago fresh and asiago soft cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.108 Brick cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.111 Caciocavallo siciliano cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.113 Cheddar cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.118 Colby cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.127 Cook cheese, koch kaese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.136 Washed curd and soaked curd cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.138 Edam cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.141 Gorgonzola cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.144 Granular and stirred curd cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.147 Grated American cheese food.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.149 Gruyere cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.152 Limburger cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.153 Monterey cheese and monterey jack cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.156 Low-moisture mozzarella and scamorza cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.157 Part-skim mozzarella and scamorza cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.164 Nuworld cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.165 Parmesan and reggiano cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.179 Pasteurized process cheese spread.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.182 Soft ripened cheeses.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.183 Romano cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.185 Samsoe cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.187 Semisoft cheeses.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.188 Semisoft part-skim cheeses.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.189 Skim milk cheese for manufacturing.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.190 Spiced cheeses.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.195 Swiss and emmentaler cheese.


FDA PART 145 -- CANNED FRUITS
Subpart B--Requirements for Specific Standardized Canned Fruits
Sec. 145.145 Canned grapefruit.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.141 Artificially sweetened fruit jelly.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.161 Artificially sweetened fruit preserves and jams.


FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart F--Flavoring Agents and Related Substances
Sec. 172.560 Modified hop extract.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart B--Substances Utilized To Control the Growth of Microorganisms
Sec. 178.1010 Sanitizing solutions.


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1193 Calcium chloride.
 
Physical Properties:
Food Chemicals Codex Listed: No
Specific Gravity:0.83500 @ 25.00 °C.
Boiling Point: 100.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:24.500000 mmHg @ 25.00 °C. (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -1.380 (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Allan Chemical
Calcium Chloride Dihydrate
Amecan
Calcium Chloride Dihydrate
American Elements
Calcium Chloride Dihydrate 99%
Odor: characteristic
Use: Calcium Chloride Dihydrate is an excellent water soluble crystalline Calcium source for uses compatible with chlorides. Chloride compounds can conduct electricity when fused or dissolved in water. Chloride materials can be decomposed by electrolysis to chlorine gas and the metal. They are formed through various chlorination processes whereby at least one chlorine anion (Cl-) is covalently bonded to the relevant metal or cation. Ultra high purity and proprietary formulations can be prepared. The chloride ion controls fluid equilibrium and pH levels in metabolic systems. They can form either inorganic or organic compounds. Calcium Chloride is generally immediately available in most volumes. Ultra high purity and high purity compositions improve both optical quality and usefulness as scientific standards. Nanoscale (See also Nanotechnology Information and Quantum Dots) elemental powders and suspensions, as alternative high surface area forms, may be considered. We also produce Calcium Chloride Solution. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
Calcium Chloride Dihydrate
BOC Sciences
For experimental / research use only.
Calcium chloride dihydrate
Odor: characteristic
Use: Calcium chloride dihydrate is used as a sequestrant and firming agent in food products.
Charkit Chemical
CALCIUM CHLORIDE USP DIHYDRATE
ECSA Chemicals
CALCIUM CHLORIDE DIHYDRATE FOOD GRADE
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
ECSA Chemicals
CALCIUM CHLORIDE DIHYDRATE PHARMA
ECSA Chemicals
CALCIUM CHLORIDE DIHYDRATE RPE-ACS-FOR ANALY
EMD Millipore
For experimental / research use only.
Calcium Chloride Dihydrate
Glentham Life Sciences
Calcium chloride dihydrate
Penta International
CALCIUM CHLORIDE DIHYDRATE FCC
Penta International
CALCIUM CHLORIDE DIHYDRATE USP
Santa Cruz Biotechnology
For experimental / research use only.
Calcium Chloride Dihydrate 99%
Sigma-Aldrich
For experimental / research use only.
Calcium chloride dihydrate ACS reagent, ≥99%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 20500 mg/kg
Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. Vol. 4, Pg. 110, 1983.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
multipurpose additives, firming agents
Recommendation for calcium chloride dihydrate usage levels up to:
 not for fragrance use.
 
Recommendation for calcium chloride dihydrate flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the safety assessment of the active substances, sodium erythorbate, sodium carbonate, sodium bicarbonate, iron sulphate, activated carbon, cellulose, calcium hydroxide, calcium chloride and water, for use as active system in food contact materials
View page or View pdf

ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24844
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
calcium dichloride dihydrate
Chemidplus:0010035048
RTECS:EV9810000 for cas# 10035-04-8
 
References:
 calcium dichloride dihydrate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):24844
Pubchem (sid):134990632
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
KEGG (GenomeNet):D02256
HMDB (The Human Metabolome Database):HMDB36506
FooDB:FDB015403
Export Tariff Code:2827.20.0000
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 calcium chloride hydrate (1:2:2)
 calcium chloride, dihydrate
 calcium dichloride dihydrate
 calcium dichloride, dihydrate
 calciumchloridedihydrate
 dichlorocalcium dihydrate
 

Articles:

PubMed:A dose-finding, long-term study on the use of calcium chloride in saline solution as a method of nonsurgical sterilization in dogs: evaluation of the most effective concentration with the lowest risk.
PubMed:Alcohol diluent provides the optimal formulation for calcium chloride non-surgical sterilization in dogs.
PubMed:Crystallization and preliminary crystallographic analysis of histamine dehydrogenase from Natrinema gari BCC 24369.
PubMed:Overexpression, purification, crystallization and structure determination of AspB, a putative aspartate aminotransferase from Mycobacterium tuberculosis.
PubMed:Cytotoxicity of accelerated white MTA and Malaysian white Portland cement on stem cells from human exfoliated deciduous teeth (SHED): An in vitro study.
PubMed:Effect of calcium treatment on blood parameters, gonadal development and the structure of bone in immature female rats.
PubMed:Clinical evaluation of non-surgical sterilization of male cats with single intra-testicular injection of calcium chloride.
PubMed:Recovery and concentration of polyphenols from olive mill wastewaters by integrated membrane system.
PubMed:Apatite coating of electrospun PLGA fibers using a PVA vehicle system carrying calcium ions.
PubMed:Cytokine and IDO metabolite changes effected by calcium pterin during inhibition of MDA-MB-231 xenograph tumors in nude mice.
PubMed:XRD studies of beta-chitin from squid pen with calcium solvent.
PubMed:Alkaline earth chloride hydrates: chlorine quadrupolar and chemical shift tensors by solid-state NMR spectroscopy and plane wave pseudopotential calculations.
PubMed:Disposable diaper to collect urine samples from young children for pyrethroid pesticide studies.
PubMed:The effects of high molecular weight hydroxyethyl starch solutions on platelets.
PubMed:B-domain deleted recombinant factor VIII formulation and stability.
PubMed:Structure of the X-phase of 38% brominated betaine calcium chloride dihydrate.
PubMed:Stable and x-ray induced commensurate and incommensurate phases in betaine calcium chloride dihydrate.
PubMed:Effect of electric fields on modulated structure of deuterated betaine calcium chloride dihydrate.
PubMed:Symmetry-based model for the modulated phases of betaine calcium chloride dihydrate.
PubMed:Effect of hydrostatic pressure on the modulated structure of deuterated betaine calcium chloride dihydrate.
PubMed:Elastic neutron scattering in electric-field-biased deuterated betaine calcium chloride dihydrate.
PubMed:Elastic-neutron-scattering study of the devil's-staircase behavior in deuterated betaine calcium chloride dihydrate.
PubMed:Accumulation of structure combination branching processes in betaine calcium chloride dihydrate.
PubMed:Phase diagram of betaine calcium chloride dihydrate in an applied electric field.
PubMed:Erratum: Theory of the phase-transition sequence in betaine calcium chloride dihydrate (BCCD)
PubMed:Incommensurate phases in betaine calcium chloride dihydrate.
PubMed:Theory of the phase-transition sequence in betaine calcium chloride dihydrate (BCCD).
PubMed:Phenomenological model for the phase-transition sequence in betaine calcium chloride dihydrate.
PubMed:A simple method for staining nuclei of mature and germinated maize pollen.
PubMed:Pyroelectric detection of high-order commensurate phases with a narrow range of stability in betaine calcium chloride dihydrate.
PubMed:Multicritical point and structure branching patterns in the modulated phases of betaine calcium chloride dihydrate (BCCD).
PubMed:Reduction in ventricular fibrillation using calcium-enriched Renografin 76.
PubMed:A simple method for studying the formation of calcium oxalate.
PubMed:Interaction between cholesterol and calcium ions in solution.
 
Notes:
a salt used to replenish calcium levels, as an acid-producing diuretic, and as an antidote for magnesium poisoning. Calcium chloride is an irritant, particularly on moist skin.; Calcium chloride, CaCl2, is a common salt. It behaves as a typical ionic halide, and is solid at room temperature. It has several common applications such as brine for refrigeration plants, ice and dust control on roads, and in concrete. The anhydrous salt is also widely used as a desiccant, where it will adsorb so much water that it will eventually dissolve in its own crystal lattice water. It can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, the anhydrous form must be kept in tightly-sealed containers. It is used to turn kelp into a solid.
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