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benzyl butyl phthalate
phthalic acid, benzyl butyl ester

Supplier Sponsors

CAS Number: 85-68-7Picture of molecule3D/inchi
Other(deleted CASRN):58128-78-2
ECHA EINECS - REACH Pre-Reg:201-622-7
Nikkaji Web:J45.539C
Beilstein Number:2062204
XlogP3:4.90 (est)
Molecular Weight:312.36520000
Formula:C19 H20 O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:indirect food additives: adhesives and components of coatings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
DG SANTE Food Contact Materials:phthalic acid, benzyl butyl ester
FDA Regulation:
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.
Physical Properties:
Appearance:colorless clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.10000 @ 25.00 °C.
Melting Point: -35.00 °C. @ 760.00 mm Hg
Boiling Point: 370.00 °C. @ 760.00 mm Hg
Boiling Point: 250.00 °C. @ 22.50 mm Hg
Vapor Density:10.8 ( Air = 1 )
Flash Point:> 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 4.730
Soluble in:
 water, 2.69 mg/L @ 25 °C (exp)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: not used anymore
Odor: characteristic
Use: PLASTHALL BBP is an excellent general-purpose plasticizer with strong solvent action on a wide variety of resins. In polyvinyl chloride hot-processing operations such as calendaring or extruding, PLASTHALL BBP imparts excellent processing characteristics since it significantly reduces the molten viscosity. PLASTHALL BBP imparts excellent tear, tensile and abrasion resistance. It is outstanding among primary plasticizers in its resistance to extraction by gasoline and oil and to staining by common household materials. PLASTHALL BBP is an excellent plasticizer for nitrocellulose lacquers and films and for polyvinyl acetate. Compared to DBP, it offers greatly improved permanence (lower volatility) and improved resistance to extraction by water. Acrylic coatings plasticized with PLASTHALL BBP possess excellent gloss, resistance to water spotting and effects of humidity. It imparts excellent flowout and flexibility. These outstanding performance characteristics have made it the standard plasticizer for this type of lacquer. With ethyl cellulose, PLASTHALL BBP produces clear sheets, molding, films and hot metal (dip) compositions for packaging and protective coatings, imparting minimum heat degradation, maximum oil and water resistance, good permanence, clarity and toughness.
Penta International
Santa Cruz Biotechnology
For experimental / research use only.
Benzyl Butyl Phthalate
Sigma-Aldrich: Aldrich
For experimental / research use only.
Benzyl Butyl Phthalate 98%
Silver Fern Chemical
Benzyl Butyl Phthalate
Odor: characteristic
Use: Our Fernplast BBP, also known as Benzyl Butyl Phthalate, is comparable to Santicizer®160. It is a highly polar high performance polyurethane plasticizer. It is often favored for its low viscosity which allows for processing at low temperatures. Since Fernplast BBP is transparent, it works well for clear or light colored polymers and coatings.
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 2330 mg/kg
IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 29, Pg. 193, 1982.

oral-mouse LD50 4170 mg/kg
IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 29, Pg. 193, 1982.

oral-guinea pig LD50 13750 mg/kg
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 24(3), Pg. 25, 1980.

intraperitoneal-mouse LD50 3160 mg/kg
EHP, Environmental Health Perspectives. Vol. 4, Pg. 3, 1973.

unreported-mouse LD50 13700 ug/kg
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 32(7), Pg. 52, 1988.

Dermal Toxicity:
skin-rat LD50 6700 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(6), Pg. 25, 1974.

skin-rabbit LD50 > 10000 mg/kg
Toxicology and Industrial Health. Vol. 3, Pg. 79, 1987.

skin-mouse LD50 6700 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(6), Pg. 25, 1974.

Inhalation Toxicity:
Not determined
Safety in Use Information:
indirect food additives: adhesives and components of coatings
Recommendation for benzyl butyl phthalate usage levels up to:
 not for fragrance use.
Recommendation for benzyl butyl phthalate flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Butylbenzylphthalate (BBP) for use in food contact materials
View page or View pdf

Technical report of the public consultation on the ‘Draft update of the risk assessment of di-butylphthalate (DBP), butyl-benzyl-phthalate (BBP), bis(2-ethylhexyl)phthalate (DEHP), di-isononylphthalate (DINP) and di-isodecylphthalate (DIDP) for use in food contact materials’
View page or View pdf

Update of the risk assessment of di-butylphthalate (DBP), butyl-benzyl-phthalate (BBP), bis(2-ethylhexyl)phthalate (DEHP), di-isononylphthalate (DINP) and di-isodecylphthalate (DIDP) for use in food contact materials
View page or View pdf

EPI System: View
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA Substance Registry Services (TSCA):85-68-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :2347
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
2-O-benzyl 1-O-butyl benzene-1,2-dicarboxylate
EPA/NOAA CAMEO:hazardous materials
 2-O-benzyl 1-O-butyl benzene-1,2-dicarboxylate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:85-68-7
Pubchem (cid):2347
Pubchem (sid):134972979
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
KEGG (GenomeNet):C14211
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2917.34.0000
grade: technical
Potential Blenders and core components note
None Found
Potential Uses:
 film formers
Occurrence (nature, food, other):note
 not found in nature
1,2-benzenedicarboxylic acid benzyl butylester
1,2-benzenedicarboxylic acid butyl phenylmethyl ester
1,2-benzenedicarboxylic acid, butyl phenylmethyl ester
2-O-benzyl 1-O-butyl benzene-1,2-dicarboxylate
 benzyl butyl benzene-1,2-dicarboxylate
 benzyl N-butyl phthalate
 butyl benzyl phthalate
N-butyl benzyl phthalate
 butyl phenyl methyl 1,2-benzene dicarboxylate
 butyl phenylmethyl 1,2-benzenedicarboxylate
 butylbenzyl phthalate
 palatinol BB
 phthalic acid benzyl butyl ester
 phthalic acid benzyl N-butyl ester
 phthalic acid, benzyl butyl ester
 santicizer 160
 sicol 160
 unimoll BB


PubMed:The influence of resource strategies on childhood phthalate exposure-The role of REACH in a zero waste society.
PubMed:Contamination of wines and spirits by phthalates: types of contaminants present, contamination sources and means of prevention.
PubMed:Benzyl butyl phthalate exposure impairs learning and memory and attenuates neurotransmission and CREB phosphorylation in mice.
PubMed:Findings of 2731 suspected phthalate-tainted foodstuffs during the 2011 phthalates incident in Taiwan.
PubMed:Occurrence of Di-(2-ethylhexyl) adipate and phthalate plasticizers in samples of meat, fish, and cheese and their packaging films.
PubMed:Intake estimates of phthalate esters for South Delhi population based on exposure media assessment.
PubMed:Childhood exposure to DEHP, DBP and BBP under existing chemical management systems: a comparative study of sources of childhood exposure in Korea and in Denmark.
PubMed:Determination and pharmacokinetics of di-(2-ethylhexyl) phthalate in rats by ultra performance liquid chromatography with tandem mass spectrometry.
PubMed:Chronic exposure to benzyl butyl phthalate (BBP) alters social interaction and fear conditioning in male adult rats: alterations in amygdalar MeCP2, ERK1/2 and ERα.
PubMed:Phthalate metabolites in obese individuals undergoing weight loss: Urinary levels and estimation of the phthalates daily intake.
PubMed:Determination of phthalate diesters in foods.
PubMed:Phthalates in indoor dust in Kuwait: implications for non-dietary human exposure.
PubMed:Detection of migration of phthalates from agglomerated cork stoppers using HPLC-MS/MS.
PubMed:Occurrence and profiles of phthalates in foodstuffs from China and their implications for human exposure.
PubMed:Phthalates residues in plastic bottled waters.
PubMed:Determination of phthalate esters in soil by microemulsion electrokinetic chromatography coupled with accelerated solvent extraction.
PubMed:Alkylphenols and phthalates in bottled waters.
PubMed:Reproductive and developmental toxicity of phthalates.
PubMed:Determination of phthalates in fruit jellies by dispersive SPE coupled with HPLC-MS.
PubMed:Survey of phthalate levels in Italian oily foods contained in glass jars with PVC gaskets.
PubMed:Phthalate exposure through food and consumers' risk perception of chemicals in food.
PubMed:Simultaneous screening and determination eight phthalates in plastic products for food use by sonication-assisted extraction/GC-MS methods.
PubMed:Plastic components affect the activation of the aryl hydrocarbon and the androgen receptor.
PubMed:Determination of phthalates and adipate in bottled water by headspace solid-phase microextraction and gas chromatography/mass spectrometry.
PubMed:Analysis of consumer cosmetic products for phthalate esters.
PubMed:Determination of phthalates in milk and milk products by liquid chromatography/tandem mass spectrometry.
PubMed:Diisobutyl phthalate has comparable anti-androgenic effects to di-n-butyl phthalate in fetal rat testis.
PubMed:NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Butyl Benzyl Phthalate (BBP).
PubMed:Phthalates inhibit tamoxifen-induced apoptosis in MCF-7 human breast cancer cells.
PubMed:Decreased anogenital distance and increased incidence of undescended testes in fetuses of rats given monobenzyl phthalate, a major metabolite of butyl benzyl phthalate.
PubMed:Investigation of the adjuvant and immuno-suppressive effects of benzyl butyl phthalate, phthalic acid and benzyl alcohol in a murine injection model.
PubMed:Generation of anticalins with specificity for a nonsymmetric phthalic acid ester.
PubMed:Effects on development of the reproductive system in male offspring of rats given butyl benzyl phthalate during late pregnancy.
PubMed:Effects of endocrine disrupting chemicals on the microtubule network in Chinese hamster V79 cells in culture and in Sertoli cells in rats.
PubMed:Effect of butyl benzyl phthalate in Sprague-Dawley rats after gavage administration: a two-generation reproductive study.
PubMed:Metabolism of n-butyl benzyl phthalate in the female Wistar rat. Identification of new metabolites.
PubMed:The plasticizer benzyl butyl phthalate (BBP) inhibits 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary DNA adduct formation and tumorigenesis.
PubMed:Developmental toxicity of mono-n-benzyl phthalate, one of the major metabolites of the plasticizer n-butyl benzyl phthalate, in rats.
PubMed:Evaluation of the OECD 421 reproductive toxicity screening test protocol using butyl benzyl phthalate.
PubMed:Developmental toxicity evaluation of diethyl and dimethyl phthalate in rats.
PubMed:Embryolethality and teratogenicity of butyl benzyl phthalate in rats.
PubMed:Teratogenic evaluation of butyl benzyl phthalate in rats by gastric intubation.
PubMed:Effect of period of exposure on the developmental toxicity of butyl benzyl phthalate in rats.
PubMed:Evaluation of the embryolethality of butyl benzyl phthalate by conventional and pair-feeding studies in rats.
PubMed:Evaluation of the teratogenic potential of the plasticizer butyl benzyl phthalate in rats.
PubMed:The use of multivariate analysis to compare peroxisome induction data on phthalate esters in rats.
None found
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