EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

benzethonium chloride
N,N-dimethyl-N-[2-[2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethyl]benzenemethanaminium chloride

Supplier Sponsors

CAS Number: 121-54-0Picture of molecule3D/inchi
Other(deleted CASRN):324034-09-5
ECHA EINECS - REACH Pre-Reg:204-479-9
FDA UNII: PH41D05744
Beilstein Number:3898548
MDL:MFCD00011742
Molecular Weight:448.08914000
Formula:C27 H42 Cl N O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:indirect food additives: adhesives and components of coatings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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 FDA/DG SANTE Petitions, Reviews, Notices:
FCN 460 Benzenemethanaminium, N,N-dimethyl-N-(2-(2-(4-(1,1,3,3,-tetramethylbutyl)phenoxy)ethoxy)-ethyl)-,chloride View - notice
FDA Mainterm (IAUFC):121-54-0 ; BENZETHONIUM CHLORIDE
FDA Regulation:
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): 3.801 (est)
Soluble in:
 water, 0.5913 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antimicrobial agents
deodorants
preservatives
surfactants
 
Suppliers:
American International Chemical, LLC.
Benzethonium Chloride
BOC Sciences
For experimental / research use only.
Benzethonium Chloride >98%
Odor: characteristic
Use: Benzethonium chloride is a potent inhibitor of nAChRs, it inhibits b4 2 nAChRs and b7 nAChRs with IC50 of 49 nM and 122 nM, respectively.
Charkit Chemical
BENZETHONIUM CHLORIDE USP
EMD Millipore
For experimental / research use only.
Benzethonium Chloride
sds
Glentham Life Sciences
Benzethonium chloride
Jiangyin Healthway
Benzethonium Chloride
New functional food ingredients
Penta International
BENZETHONIUM CHLORIDE USP
Santa Cruz Biotechnology
For experimental / research use only.
Benzethonium chloride 97%
Sigma-Aldrich: Sigma
For experimental / research use only.
Benzethonium chloride BioUltra, ≥99.0% (AT)
sds
TCI AMERICA
For experimental / research use only.
Benzethonium Chloride >97.0%(HPLC)
sds
Universal Preserv-A-Chem Inc.
BENZETHONIUM CHLORIDE USP
Odor: characteristic
Use: Benzethonium chloride exhibits a broad spectrum of microbiocidal activity against bacteria, fungi, mold and viruses.
Universal Preserv-A-Chem Inc.
BENZETHONIUM CHLORIDE
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 7813 ug/kg
Journal of the American College of Toxicology. Vol. 4(5), Pg. 65, 1985.

intravenous-mouse LD50 30 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 40, Pg. 267, 1951.

oral-mouse LD50 338 mg/kg
Proceedings of the Society for Experimental Biology and Medicine. Vol. 120, Pg. 511, 1965.

intraperitoneal-rat LD50 16500 ug/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
Fukuoka Shika Daigaku Gakkai Zasshi. Journal of Fukuoka Dental College. Vol. 9, Pg. 729, 1983.

intravenous-rat LD50 19 mg/kg
BLOOD: CHANGES IN CELL COUNT (UNSPECIFIED) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) KIDNEY, URETER, AND BLADDER: HEMATURIA
Soap and Chemical Specialties. Vol. 30, Pg. 147, 1954.

oral-rat LD50 368 mg/kg
Proceedings of the Society for Experimental Biology and Medicine. Vol. 120, Pg. 511, 1965.

unreported-rat LD50 420 mg/kg
"Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 167, 1989.

Dermal Toxicity:
subcutaneous-rat LD50 119 mg/kg
National Technical Information Service. Vol. PB195-158

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
indirect food additives: adhesives and components of coatings
Recommendation for benzethonium chloride usage levels up to:
 not for fragrance use.
 
Recommendation for benzethonium chloride flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Daily Med:search
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):121-54-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :8478
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
benzyl-dimethyl-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]azanium chloride
Chemidplus:0000121540
EPA/NOAA CAMEO:hazardous materials
RTECS:121-54-0
 
References:
 benzyl-dimethyl-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]azanium chloride
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:121-54-0
Pubchem (cid):8478
Pubchem (sid):134975721
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C12539
HMDB (The Human Metabolome Database):HMDB32732
FooDB:FDB020763
Export Tariff Code:2923.90.0100
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•aqueous solution, crystals, ethanolwater solution. •v-tergent 8x, detergent- deodorant; composition: benzethonium chloride 1.6%; isopropyl alc 13.5%. applications: widely useful detergent & deodorant. liquefies pus & fatty exudates. •benzethonium chloride, usp (phemerol chloride), avail as 0.133 & 3% soln, 0.2% tincture, & 0.2% vaginal foam. •grade: national formulary.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 preservatives
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 ammonium, benzyldimethyl(2-(2-(p-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl)-, chloride
 anti-germ 77
 antiseptol
 banagerm
 benzenemethanaminium, N,N-dimethyl-N-(2-(2-(4-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)- ethyl)-, chloride
 benzenemethanaminium, N,N-dimethyl-N-(2-(2-(4-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl)-, chloride
 benzenemethanaminium, N,N-dimethyl-N-[2-[2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethyl]-, chloride
 benzenemethanaminium, N,N-dimethyl-N-[2-[2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethyl]-, chloride (1:1)
 benzethonium hydrochloride
 benzethoniumchloride
 benzetonium chloride
 benzyl-dimethyl-[2-[2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]azanium chloride
N-benzyl-N,N-dimethyl-2-{2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy}ethanaminium chloride
N-benzyl-N,N-dimethyl-2-{2-[4-(2,4,4-trimethyl-2-pentanyl)phenoxy]ethoxy}ethanaminium chloride
N-benzyl-N,N-dimethyl-2-{2-[4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy}ethanaminium chloride
 benzyldimethyl(2-(2-(4-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl)ammonium chloride
 benzyldimethyl(2-(2-(p-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl)ammonium chloride
 benzyldimethyl[2-[2-(p-1,1,3,3-tetramethylbutylphenoxy)ethoxy]ethyl]ammonium chloride
 benzyldimethyl[2-[2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethyl]ammonium chloride
 diisobutyl phenoxy ethoxy ethyl dimethyl benzyl ammonium chloride
p-diisobutyl phenoxyethoxyethyl dimethyl benzylammonium chloride
 diisobutylphenoxyethoxyethyl dimethyl benzyl ammonium chloride
p-diisobutylphenoxyethoxyethyl dimethyl benzyl ammonium chloride
 diisobutylphenoxyethoxyethyldimethyl benzyl ammonium chloride
p-diisobutylphenoxyethoxyethyldimethylbenzylammonium chloride monohydrate
N,N-dimethyl-N-(2-(2-(4-(1,1,3,3-tetramethylbutyl)phenoxy)ethoxy)ethyl)-benzenemethanaminium chloride
N,N-dimethyl-N-[2-[2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethyl]benzenemethanaminium chloride
 dimethylbenzyl(2-{2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy}ethyl)amine, chloride
 phemeride
 phemerol chloride
 phemithyn
 phermerol
 quatrachlor
 solamin
 

Articles:

PubMed:Traditionally used medicinal plants against uncomplicated urinary tract infections: Are unusual, flavan-4-ol- and derhamnosylmaysin derivatives responsible for the antiadhesive activity of extracts obtained from stigmata of Zea mays L. against uropathogenic E. coli and Benzethonium chloride as frequent contaminant faking potential antibacterial activities?
PubMed:Ototoxicity of aluminum acetate/benzethonium chloride otic solution in the chinchilla animal model.
PubMed:Differential Gene Expression of Three Gene Targets among Persistent and Nonpersistent Listeria monocytogenes Strains in the Presence or Absence of Benzethonium Chloride.
PubMed:Mechanism of HERG potassium channel inhibition by tetra-n-octylammonium bromide and benzethonium chloride.
PubMed:[Formulation of benzethonium chloride into gels].
PubMed:Synthesis, self-aggregation and biological properties of alkylphosphocholine and alkylphosphohomocholine derivatives of cetyltrimethylammonium bromide, cetylpyridinium bromide, benzalkonium bromide (C16) and benzethonium chloride.
PubMed:The effect of centrifugation on three urine protein assays: benzethonium chloride, benzalkonium chloride and pyrogallol red.
PubMed:Visual and confocal microscopic interpretation of patch tests to benzethonium chloride and benzalkonium chloride.
PubMed:Sensitization prevalence for benzalkonium chloride and benzethonium chloride.
PubMed:NTP Toxicology and Carcinogenesis Studies of Benzethonium Chloride (CAS No. 121-54-0) in F344/N Rats and B6C3F1 Mice (Dermal Studies).
PubMed:Inhibition of acetylcholine esterase and choline esterase by benzethonium chloride and avoidance of the benzethonium chloride carry-over inhibitory effect.
PubMed:[Cytotoxicity of benzethonium chloride on cultured mammalian cells].
PubMed:Benzethonium chloride: a novel anticancer agent identified by using a cell-based small-molecule screen.
PubMed:Benzethonium chloride resistance in Pseudomonas aeruginosa isolated from clinical lesions.
PubMed:Simultaneous identification and quantification by liquid chromatography of benzethonium chloride, methyl paraben and triclosan in commercial products labeled as grapefruit seed extract.
PubMed:[Properties of benzethonium chloride in micellar solutions and the effect of added sodium chloride].
PubMed:Efficacy of an alcohol-based healthcare hand rub containing synergistic combination of farnesol and benzethonium chloride.
PubMed:RELATIVE STABILITY OF PERTUSSIS VACCINE PRESERVED WITH MERTHIOLATE, BENZETHONIUM CHLORIDE, OR THE PARABENS.
PubMed:Identification of benzethonium chloride in commercial grapefruit seed extracts.
PubMed:Innervation of dromyosuppressin (DMS) immunoreactive processes and effect of DMS and benzethonium chloride on the Phormia regina (Meigen) crop.
PubMed:[Valve of the use of benzethonium chloride for turbidimetric analysis of cerebrospinal fluid proteins with an automatic analyzer].
PubMed:STABILIZATION OF PERTUSSIS VACCINE IN THE PRESENCE OF BENZETHONIUM CHLORIDE.
PubMed:Novel water-based antiseptic lotion demonstrates rapid, broad-spectrum kill compared with alcohol antiseptic.
PubMed:The enhancement effect of three sugar alcohols on the fungicidal effect of benzethonium chloride toward Candida albicans.
PubMed:Ketamine and its preservative, benzethonium chloride, both inhibit human recombinant alpha7 and alpha4beta2 neuronal nicotinic acetylcholine receptors in Xenopus oocytes.
PubMed:Synergistic inhibition of muscarinic signaling by ketamine stereoisomers and the preservative benzethonium chloride.
PubMed:Studies on the formation of electrostatic complexes between benzethonium chloride and anionic polymers.
PubMed:Transcriptome analysis of Listeria monocytogenes exposed to biocide stress reveals a multi-system response involving cell wall synthesis, sugar uptake, and motility.
PubMed:Validation of a quantitative NMR method for suspected counterfeit products exemplified on determination of benzethonium chloride in grapefruit seed extracts.
PubMed:Evaluation of an alcohol-based surgical hand disinfectant containing a synergistic combination of farnesol and benzethonium chloride for immediate and persistent activity against resident hand flora of volunteers and with a novel in vitro pig skin model.
PubMed:Determination of benzethonium chloride in anthrax vaccine adsorbed by HPLC.
PubMed:[Determination of cerebrospinal fluid proteins using the Cobas Fara centrifugal analyser. Adaptation of the turbidimetric technic to benzethonium chloride].
PubMed:A micro-method for measuring total protein in cerebrospinal fluid by using benzethonium chloride in microtiter plate wells.
PubMed:Benzethonium chloride method for proteins adapted to centrifugal analysis.
PubMed:Assessment of the benzethonium chloride method for routine determination of protein in cerebrospinal fluid and urine.
PubMed:Are the positive interferences in the benzethonium chloride method for urine protein real?
PubMed:Errors in estimating urinary protein by use of benzethonium chloride.
PubMed:[Turbidimetric protein determination with benzethonium chloride and sulfosalicylic acid].
PubMed:Effects of sodium phytate and benzethonium chloride rinses on plaque formation in humans.
PubMed:STUDIES OF PRESERVATIVES OF POLIOMYELITIS (SALK) VACCINE. I. BENZETHONIUM CHLORIDE.
PubMed:The role of pancreatic enzymes in the pathogenesis of acute pancreatitis. The failure of a trypsin inhibitor: benzethonium chloride to prevent experimental acute pancreatitis.
PubMed:Homogentisic acid interference in the measurement of urinary protein using benzethonium chloride.
PubMed:Studies on the topical treatment of experimental cutaneous leishmaniasis: the therapeutic effect of methyl benzethonium chloride and the aminoglycosides, gentamicin and paromomycin.
PubMed:Positive and negative interference in the benzethonium chloride method for urine protein.
PubMed:More on errors in estimating urinary protein by use of benzethonium chloride.
PubMed:More on quantification of urinary protein with benzethonium chloride.
PubMed:Benzethonium chloride interference with subsequent assays involving heparinized plasma in a centrifugal analyzer.
PubMed:[Assessment of the carcinogenic hazard of 6 substances used in dental practices. (1) Morphological transformation, DNA damage and sister chromatid exchanges in cultured Syrian hamster embryo cells induced by carbol camphor, eugenol, thymol, EDTA, benzalkonium chloride and benzethonium chloride].
PubMed:Benzethonium chloride method for determining proteins in cerebrospinal fluid adapted to the Greiner G300 selective analyzer.
PubMed:Vulvar dermatitis and fissures--irritant dermatitis from methyl benzethonium chloride.
PubMed:Long term anti-plaque gingivitis and calculus effects of benzethonium chloride in beagle dogs.
PubMed:The effect of benzethonium chloride on the antigens of pertussis vaccine.
PubMed:Inhibition of arylaminopeptidases and proline iminopeptidases of human whole saliva by benzethonium chloride (benzyldimethyl [2-[2-(p-1,1,3,3-tetramethylbutylphenoxy)ethoxy]-ethyl] ammonium chloride).
PubMed:The selective proteolytic enzyme inhibitory action of benzethonium chloride.
PubMed:A controlled, crossover study of a persistent antiseptic to reduce hospital-acquired infection.
PubMed:A quantitative assessment method for Ascaris eggs on hands.
PubMed:Co-delivery of chemosensitizing siRNA and an anticancer agent via multiple monocomplexation-induced hydrophobic association.
PubMed:Identification of specific pluripotent stem cell death--inducing small molecules by chemical screening.
PubMed:Automated evaluation of pharmaceutically active ionic liquids' (eco)toxicity through the inhibition of human carboxylesterase and Vibrio fischeri.
PubMed:The antimicrobial effects of ketamine combined with propofol: An in vitro study.
PubMed:Interference of cerebrospinal fluid total protein measurement by povidone-iodine contamination.
PubMed:An in vitro test of the efficacy of an anti-biofilm wound dressing.
PubMed:Methicillin-susceptible and -resistant Staphylococcus aureus with high-level antiseptic and low-level mupirocin resistance in Malaysia.
PubMed:Determination of quaternary ammonium compounds in oranges and cucumbers using QuEChERS extraction and ultra-performance liquid chromatography/tandem mass spectrometry.
PubMed:Total protein measurement in canine cerebrospinal fluid: agreement between a turbidimetric assay and 2 dye-binding methods and determination of reference intervals using an indirect a posteriori method.
PubMed:Formulation design for target delivery of iron nanoparticles to TCE zones.
PubMed:Characterization of a sodium dodecyl sulphate-degrading Pseudomonas sp. strain DRY15 from Antarctic soil.
PubMed:[Influence of temperature and concentration of a surfactant on pharmaceutical availability].
PubMed:Key role for efflux in the preservative susceptibility and adaptive resistance of Burkholderia cepacia complex bacteria.
PubMed:Ineffectiveness of a quaternary ammonium salt and povidone-iodine for the inactivation of Ascaris suum eggs.
PubMed:Effect of channel blockers on the smooth muscle of the adult crop of the queen blowfly, Phormia regina.
PubMed:High prevalence of qacA/B carriage among clinical isolates of meticillin-resistant Staphylococcus aureus in Malaysia.
PubMed:Surfactant-promoted Prussian Blue-modified carbon electrodes: enhancement of electro-deposition step, stabilization, electrochemical properties and application to lactate microbiosensors for the neurosciences.
PubMed:Biocomposite films based on alginate and organically modified clay.
PubMed:Bactericidal activity of topical antiseptics and their gargles against Bordetella pertussis.
PubMed:Comparative in vitro activities of topical wound care products against community-associated methicillin-resistant Staphylococcus aureus.
PubMed:Benzethonium increases the cytotoxicity of S(+)-ketamine in lymphoma, neuronal, and glial cells.
PubMed:Benzalkonium bromide as a new potential instillation drug for bladder cancer: hypothesis and pilot study.
PubMed:A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6.
PubMed:Potentials of mouthwashes in disinfecting cariogenic bacteria and biofilms leading to inhibition of caries.
PubMed:Evaluation of four antiseptics using a novel murine norovirus.
PubMed:Correlation between reduced susceptibility to disinfectants and multidrug resistance among clinical isolates of Acinetobacter species.
PubMed:Physiological and transcriptional characterization of persistent and nonpersistent Listeria monocytogenes isolates.
PubMed:[Resistance of Staphylococcus aureus strains to quaternary ammonium compounds and chlorhexidine].
PubMed:Comparative stabilities of glutaraldehyde & heat inactivated pertussis vaccine components of adsorbed DPT vaccine with different preservatives.
PubMed:Inhibitory effect of benzethonium and zinc chloride mouthrinses on human dental plaque and gingivitis.
PubMed:[Antibacterial effect of food additives and detergents against histamine-producing bacteria on food contact material surfaces].
PubMed:Strong interference of hemoglobin concentration on CSF total protein measurement using the trichloroacetic acid precipitation method.
PubMed:Subarachnoid ketamine in swine--pathological findings after repeated doses: acute toxicity study.
PubMed:The relative toxicity of compounds used as preservatives in vaccines and biologics.
PubMed:Comparative efficacy of hand hygiene agents in the reduction of bacteria and viruses.
PubMed:Nephelometric determination of total protein in cerebrospinal fluid and urine using benzalkonium chloride as precipitation reagent.
PubMed:Alpha 1-acid glycoprotein decreases recovery of total protein in urine when trichloroacetic acid is used to precipitate the proteins.
PubMed:Effects of high-dose major components in oral disinfectants on the cell cycle and apoptosis in primary human gingival fibroblasts in vitro.
PubMed:A facile synthesis of highly water-soluble, core-shell organo-silica nanoparticles with controllable size via sol-gel process.
PubMed:The effect of Bacillus subtilis mouth rinsing in patients with periodontitis.
PubMed:Effect of concentration and biochemical assay on the accuracy of urine dipsticks in hypertensive pregnancies.
PubMed:Three turbidimetric methods for determining total protein compared.
PubMed:Rapid antibacterial activity of 2 novel hand soaps: evaluation of the risk of development of bacterial resistance to the antibacterial agents.
PubMed:Displacement chromatography of proteins on hydrophobic charge induction adsorbent column.
PubMed:Cationic surfactants induce apoptosis in normal and cancer cells.
PubMed:A nonpeptide provides insight into mechanisms that regulate Drosophila melanogaster heart contractions.
PubMed:Comparison of cytotoxicity of various surfactants tested on normal human fibroblast cultures using the neutral red test, MTT assay and LDH release.
PubMed:Polyurethane elastomer with PEO-PTMO-PEO soft segment for sustained release of drugs.
PubMed:Inhibition of synaptosomal serotonin uptake by Ketalar.
PubMed:Surfactants selectively ablate enteric neurons of the rat jejunum.
PubMed:Studies on viral respiratory disease in laboratory cats. I. Isolation of feline herpesvirus and choice of proper disinfectant.
PubMed:Effect of two antibacterial mouth sprays and dentifrices on dental plaque and gingivitis in beagle dogs.
PubMed:A study of the relationship between albuminuria, proteinuria and urinary reagent strips.
PubMed:Effect of cationic surfactants on enhancement of firefly bioluminescence in the presence of liposomes.
PubMed:Adverse effects by artificial grapefruit seed extract products in patients on warfarin therapy.
PubMed:Hexadecyl-phosphorylcholine ointment for treatment of cutaneous leishmaniasis: an animal trial.
PubMed:Ormosil nanocomposite materials as modifiers for acrylic coating systems.
PubMed:In vitro short-time killing activity of povidone-iodine (Isodine Gargle) in the presence of oral organic matter.
PubMed:Urine protein estimation in hypertensive pregnancy: which thresholds and laboratory assay best predict clinical outcome?
PubMed:Problems with the estimation of urine protein by automated assays.
PubMed:[Relation between oxygen uptake rate and biosorption of activated sludge against chemical substance].
PubMed:Cetylpyridinium tetrachlorozincate as standard for tenside titration. Analytical methods with 1,3-dibromo-5,5-dimethylhydantoin (DBH) in respect to environmental and economical concern, part 19.
PubMed:An evaluation of protein assays for quantitative determination of drugs.
PubMed:Characteristics of hyaluronate-hydroxyethyl acrylate blend gel and release of cationic amphiphilic solutes.
PubMed:Displacement chromatography of isomers and therapeutic compounds.
PubMed:In vitro evaluation of skin sensitivity of povidone-iodine and other antiseptics using a three-dimensional human skin model.
PubMed:Application of an improved biuret method to the determination of total protein in urine and cerebrospinal fluid without concentration step by use of Hitachi 7170 auto-analyzer.
PubMed:Variability of standard clinical protein assays in the analysis of a model urine solution of fragmented albumin.
PubMed:[Quantitative analysis of factors to influence the environment of the clean room and clean bench during preparation of intravenous hyperalimentation (IVH) admixtures].
PubMed:Aspects of the antimicrobial efficacy of grapefruit seed extract and its relation to preservative substances contained.
PubMed:Characterization of associates in ternary mixtures of amines, diprotic acid dyes and quaternary ammonium compounds in dichloromethane and in dichloromethane/water systems.
PubMed:A nonpeptidal peptidomimetic agonist of the insect FLRFamide myosuppressin family.
PubMed:Effect on neonatal thyroid function of povidone-iodine used on mothers during perinatal period.
PubMed:A nonpeptide agonist of the invertebrate receptor for SchistoFLRFamide (PDVDHVFLRFamide), a member of a subfamily of insect FMRFamide-related peptides.
PubMed:Relationship between the effects on bacterial activity of selected disinfectants and the hydrophobic characters of dibasic acid diesters.
PubMed:Absence of role for plasmids in resistance to multiple disinfectants in three strains of bacteria.
PubMed:Acanthamoeba keratitis--resistance to medical therapy.
PubMed:[Ovicidal effects of heat and disinfectants on Syphacia muris estimated by in vitro hatching].
PubMed:Dipeptidyl peptidases in the soleus muscle of the rat before and after treatment with 5-hydroxytryptamine.
PubMed:Cathepsin D and 2',3'-cyclic nucleotide 3'-phosphohydrolase in developing human foetal brain.
PubMed:Contact allergy to various components of topical preparations for treatment of external otitis.
PubMed:Development of topical treatment for cutaneous leishmaniasis caused by Leishmania major in experimental animals.
PubMed:[Proline arylamidase in human serum].
PubMed:Ototoxic effect of quaternary ammonium compounds.
PubMed:Long-term antiplaque, anticalculus, and antigingivitis effects of benzethonium/polymer complex in beagle dogs.
PubMed:Effect of refrigeration on bactericidal activity of four preserved multiple-dose injectable drug products.
PubMed:Quantitative analysis of preservatives drug preparations by microbiological assay.
PubMed:Aerosol foam: a practical and effective method of contraception.
PubMed:Studies on immunity in anthrax. X. Gel-adsorbed protective antigen for immunization of man.
PubMed:Local anesthetics, antipsychotic phenothiazines, and cationic surfactants shut down intracellular reactions through membrane perturbation in yeast.
PubMed:Mixed ternary ion associate formation between xanthene dye, cinchona-alkaloid and quaternary ammonium ion and its application to the determination of trace amounts of quaternary ammonium salts in pharmaceuticals.
PubMed:Is secondary wavelength always necessary in turbidimetric urine protein measurements?
PubMed:Reduction of disinfectant bactericidal activities in clinically isolated Acinetobacter species in the presence of organic material.
PubMed:Effects of nonionic and ionic surfactants on survival, oxidative stress, and cholinesterase activity of planarian.
PubMed:Assessment using human dental pulp cells of clastogenicity of antiseptics used in dental practice and agents for root canal enlargement and cleaning.
PubMed:Presence of chemical additives and microbial inhibition capacity in grapefruit seed extracts used in apiculture.
PubMed:Development and validation of an HPLC/UV/MS method for simultaneous determination of 18 preservatives in grapefruit seed extract.
PubMed:Susceptibilities to antiseptic agents and distribution of antiseptic-resistance genes qacA/B and smr of methicillin-resistant Staphylococcus aureus isolated in Asia during 1998 and 1999.
PubMed:[Study on separation of epirubicin and doxorubicin isomers by displacement chromatography].
PubMed:Ability of fourteen chemical agents used in dental practice to induce chromosome aberrations in Syrian hamster embryo cells.
PubMed:Peptidergic innervation of the crop and the effects of an ingested nonpeptidal agonist on longevity in female Musca domestica (Diptera: Muscidae).
PubMed:Burns caused by dilute hydrofluoric acid in the bleach.
PubMed:Effectiveness of manual cleaning and disinfection of gastroendoscopes with 3% glutaraldehyde for decreasing risk of transmission of hepatitis C virus.
PubMed:Occupational allergic contact dermatitis from alkylammonium amidobenzoate.
PubMed:[Appraisal of fungistatic and fungicidal activities of quaternary compounds towards yeasts belonging to the genera Candida and Cryptococcus].
PubMed:Total protein determination in urine: elimination of a differential response between the coomassie blue and pyrogallol red protein dye-binding assays.
PubMed:The modulation of skeletal muscle contraction by FMRFamide-related peptides of the locust.
PubMed:Development of a transgenic mouse model for carcinogenesis bioassays: evaluation of chemically induced skin tumors in Tg.AC mice.
PubMed:A new approach to identifying genotoxic carcinogens: p53 induction as an indicator of genotoxic damage.
PubMed:Inactivation of human viruses by povidone-iodine in comparison with other antiseptics.
PubMed:Quantitative comparison of cytotoxicity of dental antiseptics to normal human oral keratinocytes in vitro.
PubMed:Measuring urinary protein with the new BioRad reagent kit: evaluation and comparison with five other methods.
PubMed:The analysis of quaternary ammonium compounds in human urine by direct inlet electron impact ionization mass spectrometry.
PubMed:[The influence of disinfectants on colloidal impression materials and dental stones].
PubMed:Determination of benzalkonium chloride in contact lens solutions by positive-ion fast atom bombardment mass spectrometry.
PubMed:Inactivation of Bacillus piliformis spores by heat and certain chemical disinfectants.
PubMed:Human and bovine brain cathepsin L and cathepsin H: purification, physico-chemical properties, and specificity.
PubMed:[Assay of proteins in the urine and cerebrospinal fluid. Choice of a method in centrifugal analysis].
PubMed:Purification and properties of dipeptidase from Escherichia coli AJ005.
PubMed:[Protein determination in urine--a critical review].
PubMed:Direct quantitation of antiseptic quaternary ammonium compounds by fast atom bombardment mass spectrometry.
PubMed:Improved Ellman procedure for erythrocyte cholinesterase.
PubMed:Potentiometric titration of thiols, cationic surfactants and halides using a solid-state silver-silver sulphide electrode.
PubMed:Intrathecal ketamine with preservative - histological effects on spinal nerve roots of baboons.
PubMed:Effects of intrathecal saline and ketamine with and without preservative on the spinal nerve roots of monkeys.
PubMed:New micro-turbidimetric method for determination of protein in cerebrospinal fluid and urine.
PubMed:Direct spectorphotometric assay of quaternary ammonium compounds using bromthymol blue.
PubMed:Basic studies on the viability of El Tor vibrios.
 
Notes:
bactericidal cationic quaternary ammonium surfactant used as a topical anti-infective agent. it is an ingredient in medicaments, deodorants, mouthwashes, etc., and is used to disinfect apparatus, etc., in the food processing and pharmaceutical industries, in surgery, and also as a preservative. the compound is toxic orally as a result of neuromuscular blockade. Constit. of Annona glabra (pond apple), Annona muricata (soursop) and Annona reticulata (custard apple)
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