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barium sulfate
sulfuric acid, barium salt (1:1)

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Name:barium(2+) sulfate
CAS Number: 7727-43-7Picture of molecule3D/inchi
Other(deleted CASRN):12751-32-5
ECHA EINECS - REACH Pre-Reg:231-784-4
Nikkaji Web:J2.268C
Molecular Weight:233.38880000
Formula:Ba O4 S
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:indirect food additives: adhesives and components of coatings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Pubchem Patents:Search
DG SANTE Food Contact Materials:sulfuric acid, barium salt (1:1)
FDA Mainterm (IAUFC):7727-43-7 ; BARIUM SULFATE
FDA Regulation:
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.
Physical Properties:
Appearance:white to pale yellow powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:4.50000 @ 25.00 °C.
Melting Point:1580.00 °C. @ 760.00 mm Hg
Boiling Point: 330.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000034 mmHg @ 25.00 °C. (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -1.031 (est)
Soluble in:
 water, 8470 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data2
CosIng:cosmetic data
Cosmetic Uses: cosmetic colorants
opacifying agents
American Elements
Barium Sulfate 99%
Odor: characteristic
Use: Barium Sulfate is a moderately water and acid soluble Barium source for uses compatible with sulfates.Sulfate compounds are salts or esters of sulfuric acid formed by replacing one or both of the hydrogens with a metal. Most metal sulfate compounds are readily soluble in water for uses such as water treatment, unlike fluorides and oxides which tend to be insoluble. Organometallic forms are soluble in organic solutions and sometimes in both aqueous and organic solutions. Metallic ions can also be dispersed utilizing suspended or coated nanoparticles (See also application discussion at Nanotechnology Information and at Quantum Dots) and deposited utilizing sputtering targets and evaporation materials for uses such as solar energy materials and fuel cells. Barium Sulfate is generally immediately available in most volumes. Ultra high purity and high purity compositions improve both optical quality and usefulness as scientific standards. Nanoscale (See also Nanotechnology Information and Quantum Dots) elemental powders and suspensions, as alternative high surface area forms, may be considered. We also produce Barium Sulfate Solution. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
Barium & Chemicals
Barium Sulfate Technical Precipitated Powder
Odor: characteristic
Use: Manufacture of photographic papers, artificial ivory, cellophane, and filler for rubber, linoleum, oil cloth polymeric fibers and resins, paper, lithographic inks and as a water-color pigment for colored paper in wall paper. Other applications include uses as a size for modifying the colors of other pigments and in manufacture of heavy concrete for radiation shield.
Charkit Chemical
ECSA Chemicals
Glentham Life Sciences
Barium sulfate, 99%
Kraft Chemical
Barium Sulfate
Penta International
Santa Cruz Biotechnology
For experimental / research use only.
Barium Sulfate
Sigma-Aldrich: Aldrich
For experimental / research use only.
Barium Sulfate 99.998% trace metals basis
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intratracheal-mouse LD > 600 uL/kg
Oyo Yakuri. Pharmacometrics. Vol. 50, Pg. 123, 1995.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
indirect food additives: adhesives and components of coatings
Recommendation for barium sulfate usage levels up to:
 not for fragrance use.
Recommendation for barium sulfate flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
Daily Med:search
NIOSH International Chemical Safety Cards:search
NIOSH Pocket Guide:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):7727-43-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24414
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:nwg
barium(2+) sulfate
EPA/NOAA CAMEO:hazardous materials
 barium(2+) sulfate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7727-43-7
Pubchem (cid):24414
Pubchem (sid):134989507
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
KEGG (GenomeNet):D02052
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2833.27.0000
FDA Color Additive Status ListView
•anatrast is a cherry flavored, ready-to-use barium sulfate usp suspension paste. the product contains 100% wv (56% ww) barium sulfate usp, sorbitol, suspending and dispersing agents, simethicone, flavoring, preservatives and water. •baricon is a lemon-vanilla flavored, high density barium sulfate formulation. the product contains 98% ww barium sulfate usp, sucrose, simethicone, suspending agents, sorbitol, flavoring, sodium citrate and saccharin sodium. •baro-cat is a banana-pineapple flavored ready-to-use barium sulfate suspension. the contrast medium contains 1.5% ww (wv) barium sulfate usp, with sorbitol, simethicone, suspending agent, potassium sorbate, citric acid, flavoring, saccharin sodium and water. •barobag is a complete 3 liter enema kit containing a barium sulfate formulation for aqueous suspension. the contrast medium contains approximately 97% ww barium sulfate usp, suspending agents, dispersing agents, and simethicone. •barosperse is a vanilla flavored barium sulfate product. an aqueous suspension of the product is to be prepared at the time of administration. the contrast medium contains 95% barium sulfate usp, dispersing and suspending agents, flavoring, simethicone, and saccharin sodium •cheetah is a quick-flowing, ready-to-use barium sulfate suspension. the contrast medium contains 2.2% ww barium sulfate usp, sorbitol, simethicone, suspending agent, sodium benzoate, flavoring, potassium sorbate, citric acid, saccharin sodium and water. •enhancer is a lemon-vanilla flavored, high density barium sulfate formulation. the product contains 98% ww barium sulfate usp, sucrose, simethicone, suspending agents, sorbitol, flavoring, sodium citrate and saccharin sodium. •entrobar is a raspberry flavored barium sulfate suspension. the product contains 50% wv barium sulfate usp, suspending and dispersing agents, simethicone, citric acid, potassium sorbate, flavoring, sodium citrate, saccharin sodium and water. •flo-coat is a raspberry-vanilla flavored, low viscosity, rapid flowing suspension of barium sulfate usp. the product contains 100% wv barium sulfate usp, suspending and dispersing agents, simethicone, citric acid, potassium sorbate, sodium citrate and water. •hd 200 plus is a strawberry flavored, high density barium sulfate formulation for aqueous suspension. the product contains 98% ww barium sulfate usp, suspending agents, sucrose, saccharin sodium, simethicone and artificial flavoring. •hd 85 is a raspberry flavored barium sulfate suspension. the product contains 85% wv barium sulfate usp, suspending and dispersing agents, simethicone, citric acid, flavoring, potassium sorbate, sodium citrate, saccharin sodium and water. •intropaste is a raspberry flavored, ready-to-use barium sulfate usp suspension paste. the product contains 70% wv (44% ww) barium sulfate usp, sorbitol, suspending and dispersing agents, simethicone, flavoring, methylparaben and propylparaben (preservatives), saccharin sodium (artificial sweetener) and water. •liquid barosperse is a vanilla flavored barium sulfate suspension. the product contains 60% wv barium sulfate usp, suspending agents, flavoring, citric acid, simethicone, potassium sorbate, saccharin sodium and water. •prepcat is a strawberry flavored ready-to-use barium sulfate suspension. the contrast medium contains 1.5% ww (wv) barium sulfate usp, with sorbitol, simethicone, suspending agent, potassium sorbate, flavoring, citric acid, saccharin sodium and water. •scan c is a preservative free, vanilla flavored, ready-to-use barium sulfate suspension. the contrast medium contains 2.1% ww (wv) barium sulfate usp, with suspending agents, artificial flavoring, saccharin sodium and water. •tomocat is a strawberry flavored barium sulfate suspension concentrate. tomocat contains approximately 5% wv barium sulfate usp, suspending agents, sorbitol, citric acid, simethicone, flavoring, potassium sorbate, saccharin sodium and water. •tonopaque is a cherry flavored barium sulfate formulation. an aqueous suspension of the product is to be prepared at the time of administration. the contrast medium contains 95% barium sulfate, sorbitol, suspending agents, potassium sorbate, simethicone, flavoring and saccharin sodium. •commercially barium sulfate is sold both as natural barite ore and as a precipitated product. •lithopone, a white powder containing 20% barium sulfate, 30% zinc sulfide and less than 8% zinc oxide. •grade: technical, dry, pulp, bleached, ground, floated, natural, chemically pure, usp, x-ray •baritop 100: a suspension containing 100% wtvol of barium sulfate. baritop g powder: contains barium sulfate 97%. •entero-vu[petukhova ni; vestnik rentgenologii i radiologii 5: 61-4 (2005)] pubmed abstract
Potential Blenders and core components note
None Found
Potential Uses:
 cosmetic colorants
 opacifying agents
Occurrence (nature, food, other):note
 not found in nature
 baritop P
 barium salt of sulfuric acid
 barium sulfuricum
 barium sulphate
 barium(2+) sulfate
 c.i. 77120
 C.I. pigment white 21
 ci 77120
 CI pigment white 21
 pigment white 21
 pigment white 22
 sulfuric acid barium salt (1:1)
 sulfuric acid, barium salt (1:1)
 xylocaine viscous


PubMed:Barium toxicity and the role of the potassium inward rectifier current.
PubMed:Fatal esophageal fibrosarcoma associated to parasitism by spirurid nematode Spirocerca lupi in a dog: a case report.
PubMed:[Congenital esophageal stenosis owing to ectopic tracheobronchial remnants: report of four cases and review of the literature].
PubMed:Predictive value of symptoms and demographics in diagnosing malignancy or peptic stricture.
PubMed:Difficulty in differentiating two cases of sigmoid stenosis by diverticulitis from cancer.
PubMed:Is swallowing of all mixed consistencies dangerous for penetration-aspiration?
PubMed:Achalasia of the oesophagus in infancy: a case report.
PubMed:Huge myxoid liposarcoma of the esophagus: a case report.
PubMed:Clinical and ultrasound approach to achalasia in a child. Case report.
PubMed:Endoscopic occlusion of idiopathic benign esophago-bronchial fistula.
PubMed:Videofluorographic evaluation of mastication and swallowing of Japanese udon noodles and white rice.
PubMed:Effects of respiration on soft palate movement in feeding.
PubMed:The contribution of malabsorption to the reduction in net energy absorption after long-limb Roux-en-Y gastric bypass.
PubMed:Lactic acid fermentation of germinated barley fiber and proliferative function of colonic epithelial cells in loperamide-induced rats.
PubMed:Flow properties of oral contrast medium formulations depend on the temperature.
PubMed:Long-term management of corrosive esophageal stricture with balloon dilation in children.
PubMed:Laparoscopic Heller's cardiomyotomy.
PubMed:Eosinophilic esophagitis: perspectives of adult and pediatric gastroenterologists.
PubMed:Effect of barium sulfate contrast medium on rheology and sensory texture attributes in a model food.
PubMed:Gastrointestinal motor disturbance in rabbits experimentally infected with Strongyloides papillosus.
PubMed:Correspondence between food consistency and suprahyoid muscle activity, tongue pressure, and bolus transit times during the oropharyngeal phase of swallowing.
PubMed:Evaluation of swallowing in children with vomiting after feeding.
PubMed:A question of rheological control.
PubMed:[Gastrointestinal motility--physiology and methods of measurement].
PubMed:Radiographic assessment of gastric emptying and gastrointestinal transit time in hybrid tilapia (Oreochromis niloticus x O. mossambicus).
PubMed:Radiological evaluation of covered self-expandable metallic stents used for palliation in patients with malignant esophageal strictures.
PubMed:Esophagography predicts favorable outcomes after laparoscopic Nissen fundoplication for patients with esophageal dysmotility.
PubMed:Idiopathic eosinophilic esophagitis in adults: the ringed esophagus.
PubMed:Comparison of the effect of laparoscopic and conventional pyloric surgery on gastric emptying in dogs.
PubMed:Radiographic gastrointestinal contrast study in the ostrich (Struthio camelus).
PubMed:Diverticular disease of the colon in Kampala, Uganda.
PubMed:The radiological management of oesophageal food bolus obstruction using a gas-forming agent and barium.
PubMed:Digital cineradiographic swallow study: our experience.
PubMed:Survey of stable sulfur isotope ratios (34S/32S) of sulfite and sulfate in foods.
PubMed:Therapy-related café coronary deaths: two case reports of rare asphyxial deaths in patients under supervised care.
PubMed:Successful medical treatment of two patients with eosinophilic oesophagitis.
PubMed:[Deglutition disorders in the elderly. Evaluation methods].
PubMed:The corrugated esophagus, a sign of severe reflux disease: radiographic and endoscopic appearance.
PubMed:Medical device; exemption from premarket notification; class II devices; barium enema retention catheters and tips with or without a bag. Food and Drug Administration, HHS. Final rule.
PubMed:Pseudo-achalasia following laparoscopically placed adjustable gastric banding.
PubMed:The Swedish laparoscopic adjustable gastric banding for morbid obesity: radiologic findings in 218 patients.
PubMed:Characterization of CYP4A induction in rat liver by inflammatory stimuli: dependence on sex, strain, and inflammation-evoked hypophagia.
PubMed:Esophageal rings and strictures. Manometric characteristics in patients with food impaction.
PubMed:Esophageal transit of capsules in clinically normal cats.
PubMed:The management of dysphasia in skeletal hyperostosis.
PubMed:Video fluoroscopic evaluation after glossectomy.
PubMed:Radiological demonstration of gastroesophageal reflux. Diagnostic value of barium and bread studies compared with 24-hour pH monitoring.
PubMed:Are there changes in gastric emptying during the menstrual cycle?
PubMed:Novel gastrointestinal tract manifestations in juvenile dermatomyositis.
PubMed:Cervical osteoarthropathy: an unusual cause of dysphagia.
PubMed:Differentiation of normal and abnormal airway protection during swallowing using the penetration-aspiration scale.
PubMed:Small bowel enteroclysis in surgically treated obesity.
PubMed:Esophageal stent with antireflux valve for tumors involving the cardia: work in progress.
PubMed:Food transport and bolus formation during complete feeding sequences on foods of different initial consistency.
PubMed:Schatzki ring in children and young adults: clinical and radiologic findings.
PubMed:Esophageal food impaction with early perforation.
PubMed:Radiation doses to patients during pharyngeal videofluoroscopy.
PubMed:Benefit of immediate endoscopy after radiography for anisakiasis.
PubMed:Role of the modified barium swallow in management of patients with dysphagia.
PubMed:Observation of bolus position with standardized test foods and fluoroscopic technique.
PubMed:Modified barium swallow examination in dysphagic stroke patients.
PubMed:Movement of the epiglottis in mammals.
PubMed:Pattern of gastric emptying in patients with systemic sclerosis.
PubMed:[Usefulness of the 24-hour delayed film of upper gastrointestinal series for the diagnosis of sigmoidovesical fistula: report of 3 cases].
PubMed:Intestine fullness influences feeding behaviour and crop filling in the domestic turkey.
PubMed:Effects of dietary fiber on gastrointestinal transit time, fecal properties and fat absorption in rats.
PubMed:The modified Evan's blue dye procedure fails to detect aspiration in the tracheostomized patient: five case reports.
PubMed:[Barium-pudding: a new medium for videofluoroscopic examination].
PubMed:Food poisoning with radiological changes resembling lymphoma.
PubMed:Swallowing of bolus types by postsurgical head and neck cancer patients.
PubMed:Intraluminal contrast agents for MR imaging of the abdomen and pelvis.
PubMed:Diagnosis of gastroesophageal reflux in pediatrics.
PubMed:Effect of denaturants and stabilisers on protein adsorption at solid-liquid interfaces.
PubMed:Characteristics of dysphagia in children with cerebral palsy.
PubMed:[Imaging of the esophagus. Normal and pathologic aspects].
PubMed:The use of effervescent agents in the small bowel meal examination.
PubMed:Etiology of 19 infants with apparent life-threatening events: relationship between apnea and esophageal dysfunction.
PubMed:A protocol for the videofluorographic swallowing study.
PubMed:Hypersensitivity reaction to single contrast barium meal studies in children.
PubMed:Gastric emptying of tablets and granules in humans, dogs, pigs, and stomach-emptying-controlled rabbits.
PubMed:Diagnosis of esophageal motor disorders: a prospective study comparing barium swallow, food barium mixture, and continuous swallows with manometry.
PubMed:Postprandial gastro-oesophageal reflux demonstrated by radiology.
PubMed:Videoendoscopic evaluation of patients with dysphagia: an adjunct to the modified barium swallow.
PubMed:From the Food and Drug administration.
PubMed:Influence of cisapride on food-stimulated gastro-oesophageal reflux: a radiological study.
PubMed:[Achalasia: report of two cases].
PubMed:The effect of food on the movement of pellets in the gastro-intestinal tract.
PubMed:Oesophageal transit of marshmallow after the Angelchik procedure.
PubMed:[Dynamics of food transit in gastrectomized patients with and without dumping syndrome studied with the gamma camera and a marked meal].
PubMed:Gastric drainage procedures: effects in normal dogs. II. Clinical observations and gastric emptying.
PubMed:Pulmonary aspiration studied by radionuclide milk scanning and barium swallow roentgenography.
PubMed:The incidence, reproducibility and mechanism of gastrooesophageal reflux demonstrated by radiology in normals, dyspeptics, and patients with oesophagitis.
PubMed:Effect of selective proximal vagotomy without and with pyloroplasty on gastroduodenal motility.
PubMed:Influence of food and marker length on gastric emptying of indigestible radiopaque markers in healthy humans.
PubMed:Hypersensitivity reactions after barium studies of the upper and lower gastrointestinal tract.
PubMed:Evidence for a midgastric transverse band in humans.
PubMed:Duodenal diverticula demonstrated by barium examination.
PubMed:Use of a nasogastric tube for gastric and esophageal decompression in the dog and cat.
PubMed:Food-stimulated gastro-oesophageal reflux demonstrated by barium examination.
PubMed:Disorders of gastric emptying in humans and the use of radionuclide techniques.
PubMed:Preparation for barium enema: comparison of a commercial formula diet and low-residue, clear-liquid diets in inpatients.
PubMed:Barium enema findings (? segmental colitis) in four neonates with bloody diarrhea--possible cow's milk allergy.
PubMed:Alternatives to optimal administration of tablets.
PubMed:Standardized intraabdominal abscess formation with generalized sepsis: pathophysiology in the rat.
PubMed:Gastric emptying of solid radiopaque markers: studies in healthy subjects and diabetic patients.
PubMed:[Effect of cimetidine on the gastric evacuatory function in peptic ulcer patients].
PubMed:Variables in the preparation of the large intestine for double contrast barium enema examination.
PubMed:Diverticulum and fistula of the lower cervical esophagus in a horse.
PubMed:[Diverticulosis of the colon and its complications. Surgical and clinical aspects].
PubMed:Low residual diet and hydration improving double contrast examination of the colon.
PubMed:Habitual rumination: a benign disorder.
PubMed:Barium bioavailability as the chloride, sulfate, or carbonate salt in the rat.
PubMed:Radiologic observations of gastric mixing and emptying of food in growing pigs.
PubMed:A clinical and physiological evaluation of bowel preparation for elective colorectal surgery.
PubMed:Comparison of the barium test meal and the gamma camera scanning technic in measuring gastric emptying.
PubMed:The effect of a formula diet on preparation of the colon for barium enema examination. Impact on health care and costs.
PubMed:Symptomless diverticular disease and intake of dietary fibre.
PubMed:rho-Shaped anastomosis: a reconstruction of the alimentary tract after total gastrectomy.
PubMed:The effect of hyperthyroidism on gastric emptying rates and pancreatic exocrine and biliary secretion in man.
PubMed:[Use of a standard radioactive paste in the study of esophago-gastric kinesis (author's transl)].
PubMed:[The study of preparatory method for barium enema examination of the colon with usage of a special preparatory meal "Boncolon" (author's transl)].
PubMed:[Possible use of food and contrast media mixtures for the diagnosis of the dumping syndrome].
PubMed:Electrical, contractile, and radiographic studies of the stomach after proximal gastric vagotomy.
PubMed:Stomach and upper intestine of the rat in the regulation of food intake.
PubMed:Transient post-vagotomy dysphagia: A distinct clinical and roentgenographic entity.
PubMed:Effect of 16,16-dimethylPGE2 on gastric emptying and intestinal transit of a barium-food test meal in man.
PubMed:Diverting the paralyzed larynx: a reversible procedure for intractable aspiration.
PubMed:Simple chronic constipation: pathophysiology and management.
PubMed:Gastric bezoars after gastrectomy.
PubMed:Effect of truncal, selective and highly selective vagotomy on gastric emptying and intestinal transit of a food-barium meal in man.
PubMed:Masticatory ability--cineradiographic observations.
PubMed:Markers in nutrition.
PubMed:Effect of truncal (T.V.), selective (S.V.), and highly selective vagotomy (H.S.V.) in man on gastric emptying of food and barium.
PubMed:The transport of colonic contents in the irritable colon syndrome.
PubMed:Studies on the oesophageal groove reflex in sheep and on the potential use of the groove to prevent the fermentation of food in the rumen.
PubMed:Emptying of the stomach after Billroth II resection.
PubMed:Colonic motor activity and bowel function. II. Distribution and incidence of motor activity at rest and after food and carbachol.
PubMed:[Radiologic changes in allergic enteropathy].
a compound used as an x-ray contrast medium that occurs in nature as the mineral barite. it is also used in various manufacturing applications and mixed into heavy concrete to serve as a radiation shield.
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