a sugar alcohol formed by the reduction of ribose. Ribitol is a metabolic end product formed by the reduction of ribose in human fibroblasts and erythrocytes (pentitol, sugar alcohol, polyol). Export of ribitol across the cell membrane indicates that can be cleared from the body without metabolic conversion. (PMID 15234337) Several inborn errors of metabolism with abnormal polyol concentrations in body fluids are known to date. Most of these defects can be diagnosed by the assessment of urinary concentrations of polyols. (PMID 16435188) Ribitol is normally absent in Breast milk. (PMID 16456418) [HMDB]
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pentane-1,2,3,4,5-pentol (Click)
CAS Number: 488-81-3Picture of molecule
Other: 28296-13-1
ECHA EINECS - REACH Pre-Reg: 207-685-7
Nikkaji Web: J1.453.993J
Beilstein Number: 1720524
MDL: MFCD00064291
XlogP3: -2.50 (est)
Molecular Weight: 152.14664000
Formula: C5 H12 O5
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
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IBM Patents: Obtain
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Physical Properties:
Appearance: white crystals (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 104.00 °C. @ 760.00 mm Hg
Boiling Point: 494.50 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 2.470000 mm/Hg @ 25.00 °C. (est)
Flash Point: 503.00 °F. TCC ( 261.90 °C. ) (est)
logP (o/w): -3.770 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
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Organoleptic Properties:
Taste Description:
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Cosmetic Information:
None found
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Santa Cruz Biotechnology
For experimental / research use only.
Ribitol ≥99%
Sigma-Aldrich: Sigma
For experimental / research use only.
Adonitol ≥99%
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Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50  10000 mg/kg
Proceedings of the Society for Experimental Biology and Medicine. Vol. 35, Pg. 98, 1936.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for adonitol usage levels up to:
 not for fragrance use.
Recommendation for adonitol flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
Env. Mutagen Info. Center: Search
EPA Substance Registry Services (TSCA): 488-81-3
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 827
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
Chemidplus: 0000488813
RTECS: VJ0800000 for cas# 488-81-3
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NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 488-81-3
Pubchem (cid): 827
Pubchem (sid): 134976092
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
Golm Metabolome Database: Search
Metabolomics Database: Search
KEGG (GenomeNet): D00061
HMDB (The Human Metabolome Database): HMDB00508
FooDB: FDB022083
Export Tariff Code: 2905.49.2000
Haz-Map: View
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
trade names: eutrit; kannit; klinit; kylit; newtol; torch; xyliton.
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Potential Blenders and core components note
None Found
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 found in nature
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