| PubMed:Pharmacological profile of natural and synthetic compounds with rigid adamantane-based scaffolds as potential agents for the treatment of neurodegenerative diseases |
| PubMed:Leveraging a large microbial strain collection for natural product discovery |
| PubMed:Natural products for Alzheimer's disease therapy: basic and application |
| PubMed:Biosynthesis of thiocarboxylic acid-containing natural products |
| PubMed:Challenges and opportunities for natural product discovery, production, and engineering in native producers versus heterologous hosts |
| PubMed:Soluble epoxide hydrolase inhibitors with carboranes as non-natural 3-D pharmacophores |
| PubMed:Adamantane-Substituted Acridine Donor for Blue Dual Fluorescence and Efficient Organic Light-Emitting Diodes |
| PubMed:Strain prioritization for natural product discovery by a high-throughput real-time PCR method |
| PubMed:Influenza viruses - antiviral therapy and resistance |
| PubMed:Anti-adipogenicadamantane type polycyclic polyprenylated acylphloroglucinols from Hypericum subsessile |
| PubMed:Mining and engineering natural-product biosynthetic pathways |
| PubMed:Bioisosteric substitution of adamantane with bicyclic lipophilic groups improves water solubility of human soluble epoxide hydrolase inhibitors |
| PubMed:Current approaches to exploit actinomycetes as a source of novel natural products |
| PubMed:Adamantane-Based Micro- and Ultra-Microporous Frameworks for Efficient Small Gas and Toxic Organic Vapor Adsorption |
| PubMed:Supramolecular Assembled Programmable Nanomedicine As In Situ Cancer Vaccine for Cancer Immunotherapy |
| PubMed:Synthetic versus natural receptors: supramolecular control of chemical sensing in fish |
| PubMed:Synthesis of platensimycin |
| PubMed:Acid-Responsive Adamantane-Cored Amphiphilic Block Polymers as Platforms for Drug Delivery |
| PubMed:Adipogenesis Inhibitory Activity of Hypersampsone P from Hypericum subsessile |
| PubMed:Biodegradable Redox-Sensitive Star Polymer Nanomicelles for Enhancing Doxorubicin Delivery |
| PubMed:Multimerization of an apoptogenic TRAIL-mimicking peptide by using adamantane-based dendrons |
| PubMed:Organic Functionalized Graphene Oxide Behavior in Water |
| PubMed:In-capillary derivatization with fluorescamine for the rapid determination of adamantane drugs by capillary electrophoresis with UV detection |
| PubMed:Nano-Carriers Based on pH-Sensitive Star-Shaped Copolymers for Drug-Controlled Release |
| PubMed:Rational Construction of Borromean Linked Crystalline Organic Polymers |
| PubMed:Facile Synthesis of 3-(Azol-1-yl)-1-adamantanecarboxylic Acids-New Bifunctional Angle-Shaped Building Blocks for Coordination Polymers |
| PubMed:Hyperacmosins E-G, three new homoadamantane-type polyprenylated acylphloroglucinols from Hypericum acmosepalum |
| PubMed:Total Synthesis of Dapholdhamine B and Dapholdhamine B Lactone |
| PubMed:Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus |
| PubMed:Platensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine |
| PubMed:Different modes of inhibition by adamantane amine derivatives and natural polyamines of the functionally reconstituted influenza virus M2 proton channel protein |
| PubMed:Synthesis of new pyrazolone and pyrazole-based adamantyl chalcones and antimicrobial activity |
| PubMed:3D-printable self-healing and mechanically reinforced hydrogels with host-guest non-covalent interactions integrated into covalently linked networks |
| PubMed:Discovery and syntheses of "superbug challengers"-platensimycin and platencin |
| PubMed:Biocompatible cellulose-based supramolecular nanoparticles driven by host-guest interactions for drug delivery |
| PubMed:Total synthesis of platensimycin and related natural products |
| PubMed:Late-Stage Functionalization of Platensimycin Leading to Multiple Analogues with Improved Antibacterial Activity in Vitro and in Vivo |
| PubMed:Influenza A M2 Inhibitor Binding Understood through Mechanisms of Excess Proton Stabilization and Channel Dynamics |
| PubMed:Design and synthesis of pinane oxime derivatives as novel anti-influenza agents |
| PubMed:Synthetic peroxides as potent antimalarials. News and views |
| PubMed:Fluorescent Metallacycle-Cored Amphiphilic Nanoparticles Formed by ?-Cyclodextrin-Based Host-Guest Interactions towards Cancer Theranostics |
| PubMed:Total synthesis of (ñ)-7-epi-nemorosone |
| PubMed:Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis |
| PubMed:Effect of stevia aqueous extract on the antidiabetic activity of saxagliptin in diabetic rats |
| PubMed:NF-?B/AP-1-targeted inhibition of macrophage-mediated inflammatory responses by depigmenting compound AP736 derived from natural 1,3-diphenylpropane skeleton |
| PubMed:Pip-HoGu: An Artificial Assembly with Cooperative DNA Recognition Capable of Mimicking Transcription Factor Pairs |
| PubMed:The synthetic retinoid ST1926 attenuates prostate cancer growth and potentially targets prostate cancer stem-like cells |
| PubMed:Total Synthesis of Daphniphyllum Alkaloids: From Bicycles to Diversified Caged Structures |
| PubMed:Saxagliptin alters bile acid profiles and yields metabolic benefits in drug-na‹ve overweight or obese type 2 diabetes patient |
| PubMed:Metabolism, CB1 cannabinoid receptor binding and in vivo activity of synthetic cannabinoid 5F-AKB48: Implications for toxicity |
| PubMed:Evaluation of Platensimycin and Platensimycin-Inspired Thioether Analogues against Methicillin-Resistant Staphylococcus aureus in Topical and Systemic Infection Mouse Models |
| PubMed:Platensimycin and platencin: promising antibiotics for future application in human medicine |
| PubMed:Platensimycin: a promising antimicrobial targeting fatty acid synthesis |
| PubMed:SYSU-6, A New 2-D Aluminophosphate Zeolite Layer Precursor |
| PubMed:Cytochrome P450-Catalyzed Hydroxylation Initiating Ether Formation in Platensimycin Biosynthesis |
| PubMed:A Mutasynthetic Library of Platensimycin and Platencin Analogues |
| PubMed:The boundary lipid around DMPC-spanning influenza A M2 transmembrane domain channels: Its structure and potential for drug accommodation |
| PubMed:Place in therapy for liraglutide and saxagliptin for type 2 diabetes |
| PubMed:Isothermal Titration Calorimetry Enables Rapid Characterization of Enzyme Kinetics and Inhibition for the Human Soluble Epoxide Hydrolase |
| PubMed:Review of Platensimycin and Platencin: Inhibitors of ?-Ketoacyl-acyl Carrier Protein (ACP) Synthase III (FabH) |
| PubMed:Solvophobically Driven Complexation of Adamantyl Mannoside with ?-Cyclodextrin in Water and Structured Organic Solvents |
| PubMed:Saxagliptin attenuates glomerular podocyte injury by increasing the expression of renal nephrin and podocin in type 2 diabetic rats |
| PubMed:Pharmaceuticals that contain polycyclic hydrocarbon scaffolds |
| PubMed:Biosynthetic Origin of the Ether Ring in Platensimycin |
| PubMed:Ezrin Inhibition Up-regulates Stress Response Gene Expression |
| PubMed:Versatile Layer-By-Layer Highly Stable Multilayer Films: Study of the Loading and Release of FITC-Labeled Short Peptide in the Drug Delivery Field |
| PubMed:Aminoadamantanes containing monoterpene-derived fragments as potent tyrosyl-DNA phosphodiesterase 1 inhibitors |
| PubMed:The medium is the message: glycosphingolipids and their soluble analogues |
| PubMed:Accurate Prediction of Bond Dissociation Energies and Barrier Heights for High-Energy Caged Nitro and Nitroamino Compounds Using a Coupled Cluster Theory |
| PubMed:pH-Sensitive Micelles Based on Star Copolymer Ad-(PCL-b-PDEAEMA-b-PPEGMA)? for Controlled Drug Delivery |
| PubMed:Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation |
| PubMed:Single-Chain Glycopolymer Folding via Host-Guest Interactions and Its Unprecedented Effect on DC-SIGN Binding |
| PubMed:Antibacterial, Mutagenic Properties and Chemical Characterisation of Sugar Bush (Protea caffra Meisn.): A South African Native Shrub Species |
| PubMed:Semisynthesis of Platensimycin Derivatives with Antibiotic Activities in Mice via Suzuki-Miyaura Cross-Coupling Reactions |
| PubMed:Crystal structures of cytochrome P-450CAM complexed with camphane, thiocamphor, and adamantane: factors controlling P-450 substrate hydroxylation |
| PubMed:Perturbation Independent Decay of the Loschmidt Echo in a Many-Body System |
| PubMed:Synthesis and antimicrobial evaluation of novel platensimycin analogues |
| PubMed:Chemoprophylaxis of respiratory infections |
| PubMed:Bioactive peptide functionalized aligned cyclodextrin nanofibers for neurite outgrowth |
| PubMed:Efficacy and pharmacokinetics of OZ78 and MT04 against a natural infection with Fasciola hepatica in sheep |
| PubMed:Recent advances in the chemotherapy of herpes virus infections |
| PubMed:Cucurbit[7]uril-Driven Host-Guest Chemistry for Reversible Intervention of 5-Formylcytosine-Targeted Biochemical Reactions |
| PubMed:Study of rimantadine in the USSR: a review of the literature |
| PubMed:Corrigendum to 'anti-adipogenic adamantane type polycyclic polyprenylated acylphloroglucinols from Hypericum subsessile' Fitoterapia 147, (2020) 104755 |
| PubMed:Stereocontrolled formal synthesis of (+/-)-platensimycin |
| PubMed:Antibacterial sulfur-containing platensimycin and platencin congeners from Streptomyces platensis SB12029 |
| PubMed:Biomimetic Stereoselective Sulfa-Michael Addition Leads to Platensimycin and Platencin Sulfur Analogues against Methicillin-Resistant Staphylococcus aureus |
| PubMed:Platensimycin and platencin congeners from Streptomyces platensis |
| PubMed:Synthesis, Biological Activities, and X-ray Crystal Structural Analysis of 25-Hydroxy-25(or 26)-adamantyl-17-[20(22),23-diynyl]-21-norvitamin D Compounds |
| PubMed:Synthesis and biological evaluation of all eight stereoisomers of DPP-IV inhibitor saxagliptin |
| PubMed:The bidirectional total synthesis of sampsonione P and hyperibone I |
| PubMed:7-Phenylplatensimycin and 11-methyl-7-phenylplatensimycin: more potent analogs of platensimycin |
| PubMed:Discovery of a Structurally Unique Small Molecule that Inhibits Protein Synthesis |
| PubMed:Quantitative determination of metformin, saxagliptin and 5-hydroxy saxagliptin simultaneously by hydrophilic interaction liquid chromatography - electrospray ionization mass spectrometry and its a |
| PubMed:In vivo instability of platensimycin and platencin: Synthesis and biological evaluation of urea- and carbamate-platensimycin |
| PubMed:[Development of novel drugs against influenza virus based on synthetic and natural compounds] |
| PubMed:Construction of a smart temperature-responsive GPx mimic based on the self-assembly of supra-amphiphiles |
| PubMed:Transformative hyaluronic acid-based active targeting supramolecular nanoplatform improves long circulation and enhances cellular uptake in cancer therapy |
| PubMed:Mimicking natural globular structures with rigid scaffolds based on adamantane |
| PubMed:Polycarbonate/Sulfonamide Composites with Ultralow Contents of Halogen-Free Flame Retardant and Desirable Compatibility |
| PubMed:Layer by Layer Mesoporous Silica-Hyaluronic Acid-Cyclodextrin Bifunctional "Lamination": Study of the Application of Fluorescent Probe and Host?Guest Interactions in the Drug Delivery Field |
| PubMed:A chemical genetic screen reveals that iminosugar inhibitors of plant glucosylceramide synthase inhibit root growth in Arabidopsis and cereals |
| PubMed:Platensimycin activity against mycobacterial beta-ketoacyl-ACP synthases |
| PubMed:Total synthesis and antibacterial properties of carbaplatensimycin |
| PubMed:Mechanisms of self-resistance in the platensimycin- and platencin-producing Streptomyces platensis MA7327 and MA7339 strains |
| PubMed:Synthesis of platensimycin analogues and their antibiotic potency |
| PubMed:Antitumor activity of the synthetic retinoid ST1926 on primary effusion lymphoma in vitro and in vivo models |
| PubMed:Origin of the unusual ultraviolet absorption of Arsenicin A |
| PubMed:Titer improvement and pilot-scale production of platensimycin from Streptomyces platensis SB12026 |
| PubMed:Comparison of glycemic control and ?-cell function in new onset T2DM patients with PCOS of metformin and saxagliptin monotherapy or combination treatment |
| PubMed:Sustained Small Molecule Delivery from Injectable Hyaluronic Acid Hydrogels through Host-Guest Mediated Retention |
| PubMed:DPP-4 inhibitor treatment: ?-cell response but not HbA(1c) reduction is dependent on the duration of diabetes |
| PubMed:A supramolecular DNA self-assembly based on ?-cyclodextrin-adamantane complexation as a bioorthogonal sticky end motif |
| PubMed:Dipeptidyl peptidase 8/9-like activity in human leukocytes |
| PubMed:Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis |
| PubMed:Oxyfunctionalization of non-natural targets by dioxiranes. 6. On the selective hydroxylation of cubane |
| PubMed:Establishment of a dipeptidyl peptidases (DPP) 8/9 expressing cell model for evaluating the selectivity of DPP4 inhibitors |
| PubMed:Isolation, structure and biological activities of platensimycin B4 from Streptomyces platensis |
| PubMed:Discovery and exploitation of AZADO: the highly active catalyst for alcohol oxidation |
| PubMed:Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis |
| PubMed:Engineered Streptomyces platensis strains that overproduce antibiotics platensimycin and platencin |
| PubMed:Redox-responsive mesoporous silica nanoparticles: a physiologically sensitive codelivery vehicle for siRNA and doxorubicin |
| PubMed:Simultaneous staining of sputum smears for acid-fast and lipid-containing Myobacterium tuberculosis can enhance the clinical evaluation of antituberculosis treatments |
| PubMed:Platensimycin and platencin biosynthesis in Streptomyces platensis, showcasing discovery and characterization of novel bacterial diterpene synthases |
| PubMed:Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism-of-action studies |
| PubMed:Construction of Hyaluronic Acid-Covered Hierarchically Porous MIL-nanoMOF for Loading and Controlled Release of Doxorubicin |
| PubMed:Calcium-Permeable AMPA Receptors Mediate the Induction of the Protein Kinase A-Dependent Component of Long-Term Potentiation in the Hippocampus |
| PubMed:Enhanced angiogenic effects of RGD, GHK peptides and copper (II) compositions in synthetic cryogel ECM model |
| PubMed:Structure and semisynthesis of platensimide A, produced by Streptomyces platensis |
| PubMed:ST1926, an orally active synthetic retinoid, induces apoptosis in chronic myeloid leukemia cells and prolongs survival in a murine model |
| PubMed:Synthesis and biological evaluation of chromium bioorganometallics based on the antibiotic platensimycin lead structure |
| PubMed:The binding interaction of synthetic ozonide antimalarials with natural and modified beta-cyclodextrins |
| PubMed:A genetically amenable platensimycin- and platencin-overproducer as a platform for biosynthetic explorations: a showcase of PtmO4, a long-chain acyl-CoA dehydrogenase |
| PubMed:Expression and characterization of an epoxide hydrolase from Anopheles gambiae with high activity on epoxy fatty acids |
| PubMed:Blockade of neurotensin receptors affects differently hypo-locomotion and catalepsy induced by haloperidol in mice |
| PubMed:Isoplatensimycin: Synthesis and biological evaluation |
| PubMed:Computational NMR spectroscopy of organoarsenicals and the natural polyarsenic compound arsenicin A |
| PubMed:[HIV-inhibiting activity of polyanion matrices and related substances containing adamantane and norbornene pharmacophores] |
| PubMed:Antimalarial activity of artefenomel (OZ439), a novel synthetic antimalarial endoperoxide, in patients with Plasmodium falciparum and Plasmodium vivax malaria: an open-label phase 2 trial |
| PubMed:A Simple Strategy to Construct Amorphous Metal-Free Room Temperature Phosphorescent and Multi-Color Materials |
| PubMed:Construction of a smart microgel glutathione peroxidase mimic based on supramolecular self-assembly |
| PubMed:Bioactive acylphloroglucinols with adamantyl skeleton from Hypericum sampsonii |
| PubMed:H1N1 2009 pandemic influenza virus: resistance of the I223R neuraminidase mutant explained by kinetic and structural analysis |
| PubMed:Trace analysis of total naphthenic acids in aqueous environmental matrices by liquid chromatography/mass spectrometry-quadrupole time of flight mass spectrometry direct injection |
| PubMed:Adamantyl globotriaosyl ceramide: a monovalent soluble mimic which inhibits verotoxin binding to its glycolipid receptor |
| PubMed:Structures of Pseudomonas aeruginosa ?-ketoacyl-(acyl-carrier-protein) synthase II (FabF) and a C164Q mutant provide templates for antibacterial drug discovery and identify a buried potassium ion |
| PubMed:Saxagliptin added to a thiazolidinedione improves glycemic control in patients with type 2 diabetes and inadequate control on thiazolidinedione alone |
| PubMed:A chemiluminescent substrate for the detection of phosphatidylinositol-specific phospholipase C |
| PubMed:Synthesis of an Efficient S/N-Based Flame Retardant and Its Application in Polycarbonate |
| PubMed:Metabolic mimics: thiol responsive drug release |
| PubMed:(-)-Adamantyl-delta8-tetrahydrocannabinol (AM-411), a selective cannabinoid CB1 receptor agonist: effects on open-field behaviors and antagonism by SR-141716 in rats |
| PubMed:Stereodivergent resolution of oxabicyclic ketones: preparation of key intermediates for platensimycin and other natural products |
| PubMed:Emergence of H5N1 avian influenza viruses with reduced sensitivity to neuraminidase inhibitors and novel reassortants in Lao People's Democratic Republic |
| PubMed:Acetylcholine-like and trimethylglycine-like PTA (1,3,5-triaza-7-phosphaadamantane) derivatives for the development of innovative Ru- and Pt-based therapeutic agents |
| PubMed:Synthesis and optimization of a new family of type 3 17 beta-hydroxysteroid dehydrogenase inhibitors by parallel liquid-phase chemistry |
| PubMed:Mechanism for photosynthetic O2 evolution |
| PubMed:Coronavirus helicases: attractive and unique targets of antiviral drug-development and therapeutic patents |
| PubMed:FT-IR and FT-Raman spectroscopic signatures, vibrational assignments, NBO, NLO analysis and molecular docking study of 2-{[5-(adamantan-1-yl)-4-methyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N,N-dimethyle |
| PubMed:Total synthesis of (-)-platensimycin, a novel antibacterial agent |
| PubMed:Isolation, structure and biological activities of platencin A(2)-A(4) from Streptomyces platensis |
| PubMed:A carbonyl ylide cycloaddition approach to platensimycin |
| PubMed:Syntheses and crystal structures of a series of coordination polymers constructed from C2-symmetric ligand 1,3-adamantanedicarboxylic acid |
| PubMed:Local correlation domains for coupled cluster theory: optical rotation and magnetic-field perturbations |
| PubMed:Diamondoid diacids ('O4' species) in oil sands process-affected water |
| PubMed:Illumination with ultraviolet or visible light induces chemical changes in the water-soluble manganese complex, [Mn(4)O(6)(bpea)(4)]Br(4) |
| PubMed:Total synthesis of plukenetione A |
| PubMed:Identification of a highly potent vitamin D receptor antagonist: (25S)-26-adamantyl-25-hydroxy-2-methylene-22,23-didehydro-19,27-dinor-20-epi-vitamin D3 (ADMI3) |
| PubMed:Topographic recognition of cyclic hydrocarbons and related compounds by receptors for androgens, estrogens, and glucocorticoids |
| PubMed:Isolation, structure and fatty acid synthesis inhibitory activities of platensimycin B1-B3 from Streptomyces platensis |
| PubMed:Oxyfunctionalization of non-natural targets by dioxiranes. 5. Selective oxidation of hydrocarbons bearing cyclopropyl moieties |
| PubMed:CQMUH-011 mitigates autoimmune hepatitis via inhibiting the function of T lymphocytes |
| PubMed:A full topological analysis of unstable and metastable bond critical points |
| PubMed:[Combined action of antiviral substances of natural and synthetic origin. I. The anti-influenza action of a combination of the polyphenol complex isolated from Geranium sanguineum L. and remantadi |
| PubMed:Structural and spectroscopic characterization of a novel potential anti-inflammatory agent 3-(adamantan-1-yl)-4-ethyl-1H-1,2,4-triazole-5(4H)thione by first principle calculations |
| PubMed:Single-electron self-exchange between cage hydrocarbons and their radical cations in the gas phase |
| PubMed:Chemically responsive supramolecular assemblies of pyrene-beta-cyclodextrin dimer |
| PubMed:Vaccination as a strategy to reduce the emergence of amantadine- and rimantadine-resistant strains of A/Chick/Pennsylvania/83 (H5N2) influenza virus |
| PubMed:Modification of "peptoid" CCK-B antagonists to probe requirements for CCK-B agonist activity |
| PubMed:Chemotherapy and vaccination: a possible strategy for the control of highly virulent influenza virus |
| PubMed:[Interferonogenic and antiviral activity of the double-stranded replicative form of phage f2 RNA in tissue culture and on animals] |
| PubMed:Role of K+ATP channels and EDRF in reactive hyperemia in the hindquarters vascular bed of cats |
| PubMed:Observation of a stable carbocation in a consecutive criegee rearrangement with trifluoroperacetic acid |
3D/inchi