EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

6-methoxyflavone
4H-1-benzopyran-4-one, 6-methoxy-2-phenyl-

Supplier Sponsors

Name:6-methoxy-2-phenylchromen-4-one
CAS Number: 26964-24-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:248-144-5
FDA UNII: QAX7R06N2Q
Nikkaji Web:J308.429I
Beilstein Number:0218520
MDL:MFCD00017322
XlogP3:3.90 (est)
Molecular Weight:252.26924000
Formula:C16 H12 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 421.20 °C. @ 760.00 mm Hg (est)
Flash Point: 393.00 °F. TCC ( 200.30 °C. ) (est)
logP (o/w): 3.470 (est)
Soluble in:
 water, 19.78 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
ExtraSynthese
For experimental / research use only.
6-Methoxyflavone (HPLC) ≥95%
Santa Cruz Biotechnology
For experimental / research use only.
6-Methoxyflavone 99%
Sigma-Aldrich: Aldrich
For experimental / research use only.
6-Methoxyflavone 99%
sds
TCI AMERICA
For experimental / research use only.
6-Methoxyflavone >99.0%(GC)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for 6-methoxyflavone usage levels up to:
 not for fragrance use.
 
Recommendation for 6-methoxyflavone flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :147157
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
6-methoxy-2-phenylchromen-4-one
Chemidplus:0026964249
RTECS:DJ3100438 for cas# 26964-24-9
 
References:
 6-methoxy-2-phenylchromen-4-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):147157
Pubchem (sid):135102253
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2914.50.3000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
4H-1-benzopyran-4-one, 6-methoxy-2-phenyl-
 flavone, 6-methoxy- (7CI,8CI)
6-methoxy-2-phenyl-4-benzopyrone
6-methoxy-2-phenyl-4H-1-benzopyran-4-one
6-methoxy-2-phenylchromen-4-one
 

Articles:

PubMed:6-Methoxyflavone inhibits NFAT translocation into the nucleus and suppresses T cell activation.
PubMed:Urease inhibitory constituents from Daphne retusa.
PubMed:Modulation of ionotropic GABA receptors by 6-methoxyflavanone and 6-methoxyflavone.
PubMed:A new sesquiterpene lactone from Salvia plebeia.
PubMed:Synthesis and biological evaluation of 7-O-modified oroxylin A derivatives.
PubMed:Non-covalent interaction of dietary polyphenols with total plasma proteins of type II diabetes: molecular structure/property-affinity relationships.
PubMed:Noncovalent interaction of dietary polyphenols with common human plasma proteins.
PubMed:Chemical and biological activity of leaf extracts of Chromolaena leivensis.
PubMed:Characterization of an O-methyltransferase from Streptomyces avermitilis MA-4680.
PubMed:[Chemical constituents of Laggera pterodonta].
PubMed:A new 2'-oxygenated flavone glycoside from Litsea glutinosa (Lour.) C. B. Rob.
PubMed:Flavonoids with prolyl oligopeptidase inhibitory activity isolated from Scutellaria racemosa Pers.
PubMed:Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.
PubMed:Evaluation of natural antioxidants of Leuzea carthamoides as a result of a screening study of 88 plant extracts from the European Asteraceae and Cichoriaceae.
PubMed:New dihydrochalcones and anti-platelet aggregation constituents from the leaves of Muntingia calabura.
PubMed:Use of the pig caecum model to mimic the human intestinal metabolism of hispidulin and related compounds.
PubMed:Free radical scavengers and antioxidants from Baccharis grisebachii.
PubMed:The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood-brain barrier and exhibits anticonvulsive effects.
PubMed:5,7-Dihydroxy-6-methoxyflavone, a benzodiazepine site ligand isolated from Scutellaria baicalensis Georgi, with selective antagonistic properties.
PubMed:Antiandrogenic phenolic constituents from Dalbergia cochinchinensis.
PubMed:Identification of the major degradation products of 4-methoxy-2-(3-phenyl-2-propynyl)phenol formed by exposure to air and light.
PubMed:[Studies on the structure of scuteamoenin from the root of Scutellaria amoena].
 
Notes:
None found
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