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acetamidocaproic acid
6-acetaminocaproic acid

Supplier Sponsors

Name:6-acetamidohexanoic acid
CAS Number: 57-08-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:200-310-8
FDA UNII: 7IC4BO7D3R
Nikkaji Web:J4.575F
XlogP3-AA:0.10 (est)
Molecular Weight:173.21215000
Formula:C8 H15 N O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:antioxidants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 104.50 °C. @ 760.00 mm Hg
Boiling Point: 404.50 °C. @ 760.00 mm Hg (est)
Flash Point: 389.00 °F. TCC ( 198.40 °C. ) (est)
logP (o/w): -0.500 (est)
Soluble in:
 water, 2.125e+004 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antioxidants
 
Suppliers:
BOC Sciences
For experimental / research use only.
6-Acetamidohexanoic acid > 97%
Odor: characteristic
Use: 6-Acetamidohexanoic acid is used in inhibiting the Gastrointestinal disease like gastric ulcer or small bowel inflammation. It is often used after some oral administration of ZAC(zinc acexamate), an antiulcer agent.
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
antioxidants
Recommendation for acetamidocaproic acid usage levels up to:
 not for fragrance use.
 
Recommendation for acetamidocaproic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :2005
National Institute of Allergy and Infectious Diseases:Data
6-acetamidohexanoic acid
Chemidplus:0000057089
RTECS:MO5800000 for cas# 57-08-9
 
References:
 6-acetamidohexanoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):2005
Pubchem (sid):134970696
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
KEGG (GenomeNet):D07074
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2924.10.1050
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
6-acetamidocaproic acid
6-acetamidohexanoic acid
 acetaminocaproic acid
6-acetaminocaproic acid
N-acetyl-6-aminohexanoic acid
6-(acetylamino)hexanoic acid
6-acetylaminocaproic acid
6-acetymidohexanoic acid
 hexanoic acid, 6-(acetylamino)-
 hexanoic acid, 6-(acetylamino)- (9CI)
 hexanoic acid, 6-acetamido- (8CI)
 plastenan
 

Articles:

PubMed:Induction of differentiation of human promyelocytic leukemia cells (HL60) by metabolites of hexamethylene bisacetamide
PubMed:Reduced clearance of -acetamidocaproic acid in rats with acute renal failure induced by uranyl nitrate
PubMed:-Acetamidocaproic acid pharmacokinetics in rats with gastric ulcer or small bowel inflammation
PubMed:A Bioluminescent Probe for Simultaneously Imaging Esterase and Histone Deacetylase Activity in a Tumor
PubMed:Quantification of neurotransmitters in mouse brain tissue by using liquid chromatography coupled electrospray tandem mass spectrometry
PubMed:Pharmacokinetic interaction between ?-acetamidocaproic acid (AACA) and cimetidine in indomethacin-induced acute gastric ulcer and control rats: inhibition of active renal secreti
PubMed:Phase I bioavailability and pharmacokinetic study of hexamethylene bisacetamide (NSC 95580) administered via nasogastric tube
PubMed:Identification of metabolites of the cell-differentiating agent hexamethylene bisacetamide in humans
PubMed:Alkylamides as inducers of human leukemia cell differentiation: a quantitative structure-activity relationship study using comparative molecular field analysis
PubMed:Development and Validation of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of -Acetamidocaproic Acid in Rat Plasma
PubMed:Involvement of monoamine oxidase and diamine oxidase in the metabolism of the cell differentiating agent hexamethylene bisacetamide (HMBA)
PubMed:An active, aldehydic metabolite of the cell-differentiating agent hexamethylene bisacetamide
PubMed:Pharmacokinetics and first-pass effects of epsilon-acetamidocaproic acid after administration of zinc acexamate in rats
PubMed:Direct detection of tetrahydrobiopterin (BH4) and dopamine in rat brain using liquid chromatography coupled electrospray tandem mass spectrometry
PubMed:Plasma pharmacokinetics and urinary excretion of hexamethylene bisacetamide metabolites
PubMed:Performance of human immunostimulating agents in the improvement of fish cytogenetic preparations
PubMed:Metabolism of hexamethylene bisacetamide and its metabolites in leukemic cells
PubMed:The effect of the monoamine oxidase inhibitor isocarboxazid on the canine metabolism of the cell-differentiating agent hexamethylene bisacetamide
PubMed:Effects of the monoamine oxidase inhibitor, tranylcypromine, on induction of HL60 cell differentiation by hexamethylene bisacetamide and N-acetyl-1,6-diaminohexane
PubMed:Deacetylation of alpha-keto-epsilon-acetamidocaproic acid by epsilon-lysine acylase
PubMed:Simultaneous measurement of the cell-differentiating agent hexamethylene bisacetamide and its metabolites by gas chromatography
 
Notes:
wound-healing agent component of plasmutan.
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