|
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless crystals (est) |
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Melting Point: | 146.00 to 147.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 388.14 °C. @ 760.00 mm Hg (est)
|
| Flash Point: | 349.00 °F. TCC ( 176.30 °C. ) (est)
|
| logP (o/w): | 1.891 (est) |
| Soluble in: |
| | alcohol | | | water, 1510 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for 5,7-dimethoxycoumarin usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for 5,7-dimethoxycoumarin flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2H-1- | benzopyran-2-one, 5, 7-dimethoxy- | | | citraptene | | | citropten | | | citroptene | | | coumarin, 5,7-dimethoxy- | | 5,7- | dimethoxy-2-benzopyrone | | 5,7- | dimethoxy-2H-1-benzopyran-2-one | | 5,7- | dimethoxy-2H-chromen-2-one | | 5,7- | dimethoxy-chromen-2-one | | 5,7- | dimethoxy-coumarin | | 5,7- | dimethoxychromen-2-one | | | limetin | | | limettin |
Articles:
| PubMed:Coumarins from Edgeworthia chrysantha. |
| PubMed:Analysis of Fluorescence Quenching of Coumarin Derivatives by 4-Hydroxy-TEMPO in Aqueous Solution. |
| PubMed:Simultaneous determination of 12 coumarins in bamboo leaves by HPLC. |
| PubMed:5-Geranyloxy-7-methoxycoumarin inhibits colon cancer (SW480) cells growth by inducing apoptosis. |
| PubMed:Evaluation of melanogenesis in A-375 melanoma cells treated with 5,7-dimethoxycoumarin and valproic acid. |
| PubMed:Chemical composition of hexane extract of Citrus aurantifolia and anti-Mycobacterium tuberculosis activity of some of its constituents. |
| PubMed:Synthesis and cytotoxic activity of non-naturally substituted 4-oxycoumarin derivatives. |
| PubMed:Toddaculin, a natural coumarin from Toddalia asiatica, induces differentiation and apoptosis in U-937 leukemic cells. |
| PubMed:Synthesis of (±)-8-deisopropyladunctin B. |
| PubMed:In vitro photo-induced cytotoxic activity of Citrus bergamia and C. medica L. cv. Diamante peel essential oils and identified active coumarins. |
| PubMed:New geranyloxycoumarins from Toddalia asiatica. |
| PubMed:[Chemical constituents of Lobelia chinensis]. |
| PubMed:Limettin and furocoumarins in beverages containing citrus juices or extracts. |
| PubMed:Relative photomutagenicity of furocoumarins and limettin in the hypoxanthine phosphoribosyl transferase assay in V79 cells. |
| PubMed:Inhibition of Mek 1/2 kinase activity and stimulation of melanogenesis by 5,7-dimethoxycoumarin treatment of melanoma cells. |
| PubMed:Characterization of Phaseolus vulgaris L. landraces cultivated in central Italy. |
| PubMed:New constituents of Artemisia monosperma Del. |
| PubMed:The structure-activity relationship between oxycoumarin derivatives showing inhibitory effects on iNOS in mouse macrophage RAW264.7 cells. |
| PubMed:Cell cycle arrest and differentiation induction by 5,7-dimethoxycoumarin in melanoma cell lines. |
| PubMed:Simultaneous determination of urinary metabolites of methoxypsoralens in human and Umbelliferae medicines by high-performance liquid chromatography. |
| PubMed:Toxic effects of lemon peel constituents on Ceratitis capitata. |
| PubMed:Degradation of flavonoid aglycones by rabbit, rat and human fecal flora. |
| PubMed:Earl Grey tea intoxication. |
| PubMed:Isolation and structure elucidation of a new prenylcoumarin from Murraya paniculata var. omphalocarpa (Rutaceae). |
| PubMed:Coumarin-related compounds as plant growth inhibitors from two rutaceous plants in Thailand. |
| PubMed:Isolation And Structure Elucidation Of 5,7-disubstituted Simple Coumarins In The Fruits Of Heracleum Mantegazzianum. |
| PubMed:Antibacterial activity of extracts and constituents of Pelargonium sidoides and Pelargonium reniforme. |
| PubMed:Synthesis of toddacoumaquinone, a coumarin-naphthoquinone dimer, and its antiviral activities. |
| PubMed:Rapid identification of some coumarin derivatives in deterpenated citrus peel oil by gas chromatography. |
| PubMed:Effect of occlusion on in vitro percutaneous absorption of two compounds with different physicochemical properties. |
| PubMed:[Studies on the chemical constituents of Rutaceae++ plants. LXVI. The chemical constituents of Toddalia asiatica (L.) Lam. (T. aculeata Pers.). (1). Chemical constituents of the root bark]. |
| PubMed:High-performance liquid chromatographic determination of citropten and bergapten in suction blister fluid after solar product application in humans. |
| PubMed:Citropten and bergapten suction blister fluid concentrations after solar product application in man. |
| PubMed:Isolation and characterization of the photoadducts of 5,7-dimethoxycoumarin and adenosine. |
| PubMed:Identification of psoralen, 8-methoxypsoralen, isopimpinellin, and 5,7-dimethoxycoumarin in Pelea anisata H. Mann. |
| PubMed:The photobinding of 5,7-dimethoxycoumarin to adenovirus type-2 DNA. A method for in vitro mutagenesis. |
| PubMed:Photobiological activity of 5,7-dimethoxycoumarin. |
| PubMed:A pulse radiolysis study of the complexing of furocoumarins with DNA and proteins. |
| PubMed:Photobinding of 8-methoxypsoralen and 5,7-dimethoxycoumarin to DNA and its effect on template activity. |
|
3D/inchi