4-phenyl butyric acid
butyric acid, 4-phenyl-

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  BOC Sciences

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  CODE120662 CODE120662
  Product(s):
  1821-12-1 4-Phenylbutyric acid .≥98%, >95%e.e.

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  Penta International Corporation

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  Product(s):
  16-26000 4-PHENYL BUTYRIC ACID

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  TCI AMERICA

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  Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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  Product(s):
  P0643 4-Phenylbutyric Acid >98.0%(GC)(T)
  SDS

Name: 4-phenylbutanoic acid CAS Number: 1821-12-1 3D/inchi ECHA EINECS - REACH Pre-Reg: 217-341-8 FDA UNII: 7WY7YBI87E Nikkaji Web: J101.512E Beilstein Number: 638180 MDL: MFCD00004403 XlogP3: 2.40 (est) Molecular Weight: 164.20404000 Formula: C10 H12 O2 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:pharmaceuticals / chemical synthisis   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Melting Point: 52.00 °C. @ 760.00 mm Hg Boiling Point: 290.00 °C. @ 760.00 mm Hg Vapor Pressure: 0.001000 mmHg @ 25.00 °C. (est) Flash Point: > 230.00 °F. TCC ( > 110.00 °C. ) logP (o/w): 2.420 Soluble in:   water, 1394 mg/L @ 25 °C (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: BOC Sciences For experimental / research use only. 4-Phenylbutyric acid .≥98%, >95%e.e. EMD Millipore For experimental / research use only. 4-Phenylbutyric Acid sds Frinton Laboratories For experimental / research use only. 4-Phenylbutyric Acid Penta International 4-PHENYL BUTYRIC ACID Santa Cruz Biotechnology For experimental / research use only. 4-Phenylbutyric Acid Sigma-Aldrich: Aldrich For experimental / research use only. 4-Phenylbutyric acid 99% sds TCI AMERICA For experimental / research use only. 4-Phenylbutyric Acid >98.0%(GC)(T) sds   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: Not determined Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: pharmaceuticals / chemical synthisis Recommendation for 4-phenyl butyric acid usage levels up to:   not for fragrance use.   Recommendation for 4-phenyl butyric acid flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View ClinicalTrials.gov:search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):1821-12-1 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :4775 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 4-phenylbutanoic acid Chemidplus:0001821121   References:   4-phenylbutanoic acid NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 1821-12-1 Pubchem (cid): 4775 Pubchem (sid): 134979873   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEBI: View CHEMBL: View Metabolomics Database: Search HMDB (The Human Metabolome Database): HMDB00543 FooDB: FDB022106 Export Tariff Code: 2916.39.7900 ChemSpider: View   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms:   benzenebutanoic acid   benzenebutyric acid   butyric acid, 4-phenyl- 4- phenyl-butyric acid g- phenyl-butyric acid 4- phenyl-n-butyric acid 4- phenylbutanoic acid g- phenylbutanoic acid 4- phenylbutanoicacid 4- phenylbutyric acid g- phenylbutyric acid 4- phenylbutyricacid   Articles:   None found yet. Try the PubMed Search.

Notes: 4-phenylbutyrate (4-PBA) is known to be a transcriptional regulator, and sodium-4-PBA has been shown to induce fetal hemoglobin, and it has been used in clinical trials for sickle cell anemia and β-thalassemia Because gene expression profiles became more differentiated, it is in phase I trials in several different malignant disorders. The potential for therapeutic benefit in cystic fibrosis (CF) resides in an additional mechanism, involving protein folding and the ER environment. 4-PBA is a drug that was developed to treat elevated blood ammonia in urea cycle disorders, a histone deacetylase inhibitor that promotes mutation ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) trafficking. (PMID 12458151) [HMDB]