EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

methyl morpholine oxide
morpholine, 4-methyl-, 4-oxide


CAS Number: 7529-22-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:231-391-8
Nikkaji Web:J256.599D
Beilstein Number:0507437
XlogP3-AA:-0.70 (est)
Molecular Weight:117.14807000
Formula:C5 H11 N O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:foam boosting, surfactant agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.13000 @ 25.00 °C.
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -1.820 (est)
Soluble in:
 water, 9.223e+005 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: cleansing agents
foam boosting agents
Amines & Plasticizers
N-Methylmorpholine Oxide - 50 %
Odor: characteristic
Use: Production of cellulose fifers, Pharmaceutical intermediates.
Santa Cruz Biotechnology
For experimental / research use only.
4-Methylmorpholine N-oxide 97%
Sigma-Aldrich: Aldrich
For experimental / research use only.
4-Methylmorpholine N-oxide 97%
For experimental / research use only.
4-Methylmorpholine N-Oxide (50% in Water, ca. 4.8mol/L)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
Category: foam boosting, surfactant agents
Recommendation for methyl morpholine oxide usage levels up to:
 not for fragrance use.
Recommendation for methyl morpholine oxide flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
Cancer Citations:Search
Toxicology Citations:Search
Env. Mutagen Info. Center:Search
EPA Substance Registry Services (TSCA):7529-22-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :82029
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7529-22-8
Pubchem (cid):82029
Pubchem (sid):135038583
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
UM BBD:Search
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2934.99.9000
RSC Learn Chemistry:View
Potential Blenders and core components note
None Found
Potential Uses:
Occurrence (nature, food, other):note
 not found in nature
4-methyl morpholine 4-oxide monohydrate
4-methyl morpholine N-oxide
4-methylmorpholine 4-oxide
4-methylmorpholine 4-oxide monohydrate
4-methylmorpholine 4-oxide, monohydrate
4-methylmorpholine N-oxide
N-methylmorpholine oxide
 morpholine, 4-methyl-, 4-oxide


PubMed:Iron(II) complexes supported by sulfonamido tripodal ligands: endogenous versus exogenous substrate oxidation.
PubMed:Preparation and reactivity of the versatile uranium(IV) imido complexes U(NAr)Cl₂(R₂bpy)₂ (R = Me, (t)Bu) and U(NAr)Cl₂(tppo)₃.
PubMed:Biogas production from lignocelluloses by N-methylmorpholine-N-oxide (NMMO) pretreatment: effects of recovery and reuse of NMMO.
PubMed:Biogas production from N-methylmorpholine-N-oxide (NMMO) pretreated forest residues.
PubMed:Effect of oleic acid ligand on photophysical, photoconductive and magnetic properties of monodisperse SnO2 quantum dots.
PubMed:Pretreatment of oil palm empty fruit bunch (OPEFB) by N-methylmorpholine-N-oxide (NMMO) for biogas production: structural changes and digestion improvement.
PubMed:Enzymatic saccharification of sugarcane bagasse by N-methylmorpholine-N-oxide-tolerant cellulase from a newly isolated Galactomyces sp. CCZU11-1.
PubMed:A new simple and high-yield synthesis of 5α-dihydrotestosterone (DHT), a potent androgen receptor agonist.
PubMed:Role of solvent parameters in the regeneration of cellulose from ionic liquid solutions.
PubMed:Ultrasound-assisted compatible in situ hydrolysis of sugarcane bagasse in cellulase-aqueous-N-methylmorpholine-N-oxide system for improved saccharification.
PubMed:Kinetic modeling of rapid enzymatic hydrolysis of crystalline cellulose after pretreatment by NMMO.
PubMed:Techno-economical study of ethanol and biogas from spruce wood by NMMO-pretreatment and rapid fermentation and digestion.
PubMed:Correlating physical changes and enhanced enzymatic saccharification of pine flour pretreated by N-methylmorpholine-N-oxide.
PubMed:A pilot study on lignocelluloses to ethanol and fish feed using NMMO pretreatment and cultivation with zygomycetes in an air-lift reactor.
PubMed:A novel process for ethanol or biogas production from cellulose in blended-fibers waste textiles.
PubMed:An expedient procedure for the oxidative cleavage of olefinic bonds with PhI(OAc)2, NMO, and catalytic OsO4.
PubMed:Oxidative addition to U(V)-U(V) dimers: facile routes to uranium(VI) bis(imido) complexes.
PubMed:Enhancement of ethanol and biogas production from high-crystalline cellulose by different modes of NMO pretreatment.
PubMed:Enzymatic hydrolysis of cellulose dissolved in N-methyl morpholine oxide/water solutions.
PubMed:Pretreatment of spruce and oak by N-methylmorpholine-N-oxide (NMMO) for efficient conversion of their cellulose to ethanol.
PubMed:Enhanced enzymatic hydrolysis of sugarcane bagasse by N-methylmorpholine-N-oxide pretreatment.
PubMed:Regenerated cellulose-silk fibroin blends fibers.
PubMed:N-Methylmorpholine-N-oxide ring cleavage registration by ESR under heating conditions of the Lyocell process.
PubMed:Kinetics of cellulose regeneration from cellulose--NaOH--water gels and comparison with cellulose--N-methylmorpholine-N-oxide--water solutions.
PubMed:Luminescent property and catalytic activity of Ru(II) carbonyl complexes containing N, O donor of 2-hydroxy-1-naphthylideneimines.
PubMed:'Pincer' dicarbene complexes of some early transition metals and uranium.
PubMed:Wet spinning of Bombyx mori silk fibroin dissolved in N-methyl morpholine N-oxide and properties of regenerated fibres.
PubMed:Kinetics of precipitation of cellulose from cellulose-NMMO-water solutions.
PubMed:Solubility and rheological behavior of silk fibroin (Bombyx mori) in N-methyl morpholine N-oxide.
PubMed:Kinetic and chemical studies on the isomerization of monosaccharides in N-methylmorpholine-N-oxide (NMMO) under Lyocell conditions.
PubMed:Synthesis of 2-fluoronoraristeromycin and its inhibitory activity against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase.
PubMed:Novel Oxidative Transformation of Indenoisoquinolines to Isoquinoline-3-spiro-3'-phthalides in the Presence of Osmium Tetraoxide and 4-Methylmorpholine N-Oxide.
PubMed:Swelling and dissolution of silk fibroin (Bombyx mori) in N-methyl morpholine N-oxide.
PubMed:Biodegradation of N-methylmorpholine-N-oxide.
PubMed:High substrate specificity and induction characteristics of trimethylamine-N-oxide reductase of Escherichia coli.
PubMed:Tetrapropylammonium perruthenate as a mild and efficient oxidant for sensitive steroidal alcohols.
PubMed:4-Methylmorpholine N-oxide-methyl sulfoxide soluble glucan of Piptoporus betulinus.
PubMed:Cell-wall glucans of Cryptococcus neoformans Cap 67.
PubMed:Pollen sporoplasts: dissolution of pollen walls.
None found
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