EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

3-glycidoxypropyl trimethoxysilane
silane, trimethoxy[3-(oxiranylmethoxy)propyl]-

Supplier Sponsors

CAS Number: 2530-83-8Picture of molecule3D/inchi
Other(deleted CASRN):108727-79-3
ECHA EINECS - REACH Pre-Reg:219-784-2
FDA UNII: 5K9X9X899R
Nikkaji Web:J48.152A
Beilstein Number:4308125
MDL:MFCD00005144
Molecular Weight:236.33970000
Formula:C9 H20 O5 Si
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:nail conditioning agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
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Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.07000 @ 25.00 °C.
Boiling Point: 299.35 °C. @ 760.00 mm Hg (est)
Flash Point:> 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 0.280 (est)
Soluble in:
 water, 1.7e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: nail conditioning
 
Suppliers:
Achiewell
For experimental / research use only.
3-Glycidoxypropyl trimethoxysilane
BOC Sciences
For experimental / research use only.
Silane coupler KH-560 >95.0%(GC)
Santa Cruz Biotechnology
For experimental / research use only.
(3-Glycidyloxypropyl)trimethoxysilane 97%
Sigma-Aldrich: Aldrich
For experimental / research use only.
(3-Glycidyloxypropyl)trimethoxysilane ≥98%
sds
TCI AMERICA
For experimental / research use only.
3-Glycidoxypropyltrimethoxysilane >97.0%(GC)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 22600 uL/kg
Union Carbide Data Sheet. Vol. 2/11/1964

Dermal Toxicity:
skin-rabbit LD50 3970 uL/kg
American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.

Inhalation Toxicity:
inhalation-rat LCLo 5300 mg/m3/4H
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
Office of Toxic Substances Report. Vol. OTS215156
 
Safety in Use Information:
Category:
nail conditioning agents
Recommendation for 3-glycidoxypropyl trimethoxysilane usage levels up to:
 not for fragrance use.
 
Recommendation for 3-glycidoxypropyl trimethoxysilane flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Safety assessment of the substance [3-(2,3-epoxypropoxy)propyl]trimethoxy silane, for use in food contact materials
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):2530-83-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :17317
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
trimethoxy-[3-(oxiran-2-ylmethoxy)propyl]silane
Chemidplus:0002530838
RTECS:VV4025000 for cas# 2530-83-8
 
References:
 trimethoxy-[3-(oxiran-2-ylmethoxy)propyl]silane
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:2530-83-8
Pubchem (cid):17317
Pubchem (sid):134982082
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2931.90.9010
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
3-(2,3-epoxypropoxy)propyl trimethoxysilane
(3-(2,3-epoxypropoxy)propyl)trimethoxysilane
[3-(2,3-epoxypropoxy)propyl]trimethoxysilane
3-(2,3-epoxypropoxy)propyltrimethoxysilane
3-glycidoxypropyl(trimethoxy)silane
(3-glycidoxypropyl)trimethoxysilane
3-glycidoxypropyltrimethoxysilane
 glycidyl 3-(trimethoxysilyl)propyl ether
(3-(glycidyloxy)propyl)trimethoxysilane
[3-(glycidyloxy)propyl]trimethoxysilane
(3-glycidyloxypropyl)trimethoxysilane
 glycidyloxypropyltrimethoxysilane
3-glycidyloxypropyltrimethoxysilane
 silane, (3-(2,3-epoxypropoxy)propyl)trimethoxy-
 silane, [3- (2, 3-epoxypropoxy)propyl]trimethoxy-
 silane, [3-(2,3-epoxypropoxy)propyl]trimethoxy-
 silane, 3-(2,3-epoxypropoxy)propyltrimethoxy-
 silane, 3-glycidoxypropyltrimethoxy-
 silane, 3(glycidoxy)propyl trimethoxy-
 silane, trimethoxy(3-(oxiranylmethoxy)propyl)-
 silane, trimethoxy[3- (oxiranylmethoxy)propyl]-
 silane, trimethoxy[3-(oxiranylmethoxy)propyl]-
 silicone A 187
 silicone A-187
 trimethoxy-[3-(oxiran-2-ylmethoxy)propyl]silane
 trimethoxy-g-glycidoxypropylsilane
 trimethoxy(3-(oxiran-2-ylmethoxy)propyl)silane
 trimethoxy[3-(2-oxiranylmethoxy)propyl]silane
 trimethoxy[3-(oxiran-2-ylmethoxy)propyl]silane
((3-(trimethoxysilyl)propoxy)methyl)oxirane
[[3-(trimethoxysilyl)propoxy]methyl]oxirane
3-(trimethoxysilyl)propyl glycidyl ether
 

Articles:

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PubMed:Indium-tin-oxide thin film transistor biosensors for label-free detection of avian influenza virus H5N1.
PubMed:Development of fluorescent nanoparticle-labeled lateral flow assay for the detection of nucleic acids.
PubMed:The production of concentrated dispersions of few-layer graphene by the direct exfoliation of graphite in organosilanes.
PubMed:Manipulation of interfacial amine density in epoxy-amine systems as studied by near-edge X-ray absorption fine structure (NEXAFS).
PubMed:Molecular level understanding of adhesion mechanisms at the epoxy/polymer interfaces.
PubMed:Headgroup effect on silane structures at buried polymer/silane and polymer/polymer interfaces and their relations to adhesion.
PubMed:Bactericidal core-shell paramagnetic nanoparticles functionalized with poly(hexamethylene biguanide).
PubMed:Molecular switching fluorescence based high sensitive detection of label-free C-reactive protein on biochip.
PubMed:Ag-TiO2 nanoparticle codoped SiO2 films on ZrO2 barrier-coated glass substrates with antibacterial activity in ambient condition.
PubMed:Highly condensed epoxy-oligosiloxane-based hybrid material for transparent low-k dielectric coatings.
PubMed:Removal of heavy metals from artificial metals contaminated water samples based on micelle-templated silica modified with pyoverdin I.
PubMed:Electrochromatographic evaluation of diol-bonded silica monolith capillary column for separation of basic compounds.
PubMed:Route to smooth silica-based surfaces decorated with novel self-assembled monolayers (SAMs) containing glycidyl-terminated very long hydrocarbon chains.
PubMed:Development of redox-labeled electrochemical immunoassay for polycyclic aromatic hydrocarbons with controlled surface modification and catalytic voltammetric detection.
PubMed:Organic-inorganic hybrid compounds containing polyhedral oligomeric silsesquioxane for conservation of stone heritage.
PubMed:Covalent modification of fused silica capillaries with quaternized polyamines to achieve robust and stable anodic electroosmotic flow.
PubMed:Understanding molecular structures of silanes at buried polymer interfaces using sum frequency generation vibrational spectroscopy and relating interfacial structures to polymer adhesion.
PubMed:AFM nanometer surface morphological study of in situ electropolymerized neutral red redox mediator oxysilane sol-gel encapsulated glucose oxidase electrochemical biosensors.
PubMed:Gelatin-siloxane hybrid scaffolds with vascular endothelial growth factor induces brain tissue regeneration.
PubMed:Non-Faradaic electrochemical detection of protein interactions by integrated neuromorphic CMOS sensors.
PubMed:An impedimetric immunosensor based on interdigitated microelectrodes (IDmicroE) for the determination of atrazine residues in food samples.
PubMed:Development of a new C14 monolithic silica column containing embedded polar groups for pressurized capillary electrochromatography.
PubMed:Preparation and characterization of sensing membranes for the detection of glucose, lactate and tyramine in microtiter plates.
PubMed:Design and application of a flow cell for carbon-film based electrochemical enzyme biosensors.
PubMed:Diffusion of one or more components of a silane adhesion-promoting mixture into poly(methyl methacrylate).
PubMed:A Love wave immunosensor for whole E. coli bacteria detection using an innovative two-step immobilisation approach.
PubMed:Epoxy-silane linking of biomolecules is simple and effective for patterning neuronal cultures.
PubMed:Sum frequency generation vibrational spectroscopic studies on a silane adhesion-promoting mixture at a polymer interface.
PubMed:Implantation of a new porous gelatin-siloxane hybrid into a brain lesion as a potential scaffold for tissue regeneration.
PubMed:Hygrothermal degradation of (3-glycidoxypropyl)trimethoxysilane films studied by neutron and X-ray reflectivity and attenuated total reflection infrared spectroscopy.
PubMed:Sum frequency generation studies at poly(ethylene terephthalate)/silane interfaces: hydrogen bond formation and molecular conformation determination.
PubMed:The interaction at the solid/liquid interface of 2,4-dichlorophenoxyacetic acid with silica modified by reaction with ammonia gas.
PubMed:The effects of network structure on the resistance of silane coupling agent layers to water-assisted crack growth.
PubMed:Frequency dependent and surface characterization of DNA immobilization and hybridization.
PubMed:Electrical frequency dependent characterization of DNA hybridization.
PubMed:In situ polymerization of 3-glycidoxypropyl trimethoxysilane (GLYTS) as a new tool for stone conservation.
PubMed:Chemically L-phenylalaninamide-modified monolithic silica column prepared by a sol-gel process for enantioseparation of dansyl amino acids by ligand exchange-capillary electrochromatography.
PubMed:A 27Al MAS, MQMAS and off-resonance nutation NMR study of aluminium containing silica-based sol-gel materials.
 
Notes:
None found
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