EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

3-glycidoxypropyl trimethoxysilane
silane, trimethoxy[3-(oxiranylmethoxy)propyl]-

Supplier Sponsors

CAS Number: 2530-83-8Picture of molecule3D/inchi
Other(deleted CASRN):108727-79-3
ECHA EINECS - REACH Pre-Reg:219-784-2
Nikkaji Web:J48.152A
Beilstein Number:4308125
Molecular Weight:236.33970000
Formula:C9 H20 O5 Si
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:nail conditioning agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.07000 @ 25.00 °C.
Boiling Point: 299.35 °C. @ 760.00 mm Hg (est)
Flash Point:> 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): 0.280 (est)
Soluble in:
 water, 1.7e+005 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: nail conditioning
For experimental / research use only.
3-Glycidoxypropyl trimethoxysilane
BOC Sciences
For experimental / research use only.
Silane coupler KH-560 >95.0%(GC)
Santa Cruz Biotechnology
For experimental / research use only.
(3-Glycidyloxypropyl)trimethoxysilane 97%
Sigma-Aldrich: Aldrich
For experimental / research use only.
(3-Glycidyloxypropyl)trimethoxysilane ≥98%
For experimental / research use only.
3-Glycidoxypropyltrimethoxysilane >97.0%(GC)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 22600 uL/kg
Union Carbide Data Sheet. Vol. 2/11/1964

Dermal Toxicity:
skin-rabbit LD50 3970 uL/kg
American Industrial Hygiene Association Journal. Vol. 30, Pg. 470, 1969.

Inhalation Toxicity:
inhalation-rat LCLo 5300 mg/m3/4H
Office of Toxic Substances Report. Vol. OTS215156

Safety in Use Information:
nail conditioning agents
Recommendation for 3-glycidoxypropyl trimethoxysilane usage levels up to:
 not for fragrance use.
Recommendation for 3-glycidoxypropyl trimethoxysilane flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Safety assessment of the substance [3-(2,3-epoxypropoxy)propyl]trimethoxy silane, for use in food contact materials
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):2530-83-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :17317
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
RTECS:VV4025000 for cas# 2530-83-8
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:2530-83-8
Pubchem (cid):17317
Pubchem (sid):134982082
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2931.90.9010
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
3-(2,3-epoxypropoxy)propyl trimethoxysilane
 glycidyl 3-(trimethoxysilyl)propyl ether
 silane, (3-(2,3-epoxypropoxy)propyl)trimethoxy-
 silane, [3- (2, 3-epoxypropoxy)propyl]trimethoxy-
 silane, [3-(2,3-epoxypropoxy)propyl]trimethoxy-
 silane, 3-(2,3-epoxypropoxy)propyltrimethoxy-
 silane, 3-glycidoxypropyltrimethoxy-
 silane, 3(glycidoxy)propyl trimethoxy-
 silane, trimethoxy(3-(oxiranylmethoxy)propyl)-
 silane, trimethoxy[3- (oxiranylmethoxy)propyl]-
 silane, trimethoxy[3-(oxiranylmethoxy)propyl]-
 silicone A 187
 silicone A-187
3-(trimethoxysilyl)propyl glycidyl ether


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None found
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