EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

3-aminopropane sulfonic acid
3-aminopropanesulfonic acid

Supplier Sponsors

CAS Number: 3687-18-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:222-977-4
Beilstein Number:1698848
XlogP3-AA:-3.80 (est)
Molecular Weight:139.17433000
Formula:C3 H9 N O3 S
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:hydrotrope, surfactant agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -2.250 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: surfactants
surfactant - hydrotrope
BOC Sciences
For experimental / research use only.
Odor: characteristic
Use: Tramiprosate, also nemed homotaurine, is an orally-administered, sulfated glycosaminoglycan mimic that targets amyloid ?. ?-secretase: IC50 = 12 nM; A?40: IC50 = 7.4 nM; A?42: IC50 = 7.9 nM; gamma-secretase express: EC5050 = 7 nM (CHO cells ); displacem Anti-Alzheimer agents; Amyloid-? inhibitor
Santa Cruz Biotechnology
For experimental / research use only.
Tramiprosate ≥99%
Sigma-Aldrich: Aldrich
For experimental / research use only.
3-Amino-1-propanesulfonic acid 97%
For experimental / research use only.
3-Amino-1-propanesulfonic Acid >98.0%(T)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
hydrotrope, surfactant agents
Recommendation for 3-aminopropane sulfonic acid usage levels up to:
 not for fragrance use.
Recommendation for 3-aminopropane sulfonic acid flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :1646
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
3-aminopropane-1-sulfonic acid
 3-aminopropane-1-sulfonic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):1646
Pubchem (sid):135035612
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C03349
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2921.19.6090
Potential Blenders and core components note
None Found
Potential Uses:
Occurrence (nature, food, other):note
 not found in nature
3-amino-1-propane sulfonic acid
3-amino-1-propanesulfonic acid
3-aminopropane-1-sulfonic acid
3-aminopropane-1-sulphonic acid
3-aminopropanesulfonic acid
3-aminopropanesulphonic acid
1-propanesulfonic acid, 3-amino-
1-propanesulfonic acid, 3-amino- (8CI)(9CI)


PubMed:Action of taurine, 3-aminopropanesulfonic acid, and GABA on the hindgut and heart of the cockroach, Leucophaea maderae.
PubMed:Homotaurine (3 aminopropanesulfonic acid; 3APS) protects from the convulsant and cytotoxic effect of systemically administered kainic acid.
PubMed:Effect of 3-aminopropanesulfonic acid and allylglycine on prolactin release in male rats.
PubMed:Competitive inhibition by 3-aminopropanesulfonic acid and gamma-aminobutyric acid of carnitine transport in rat brain slices.
PubMed:[Effect of 3-aminopropanesulfonic acid of the electric activity of the cerebral cortex].
PubMed:An efficient approach for recombinant expression and purification of the viral capsid protein from beak and feather disease virus (BFDV) in Escherichia coli.
PubMed:A role for glutamate-333 of Saccharomyces cerevisiae cystathionine γ-lyase as a determinant of specificity.
PubMed:Baclofen selectively inhibits transmission at synapses made by axons of CA3 pyramidal cells in the hippocampal slice.
PubMed:GABAB receptor-mediated mechanisms in human intestine in vitro.
PubMed:Interactions of taurine and structurally related analogues with the GABAergic system and taurine binding sites of rabbit brain.
PubMed:Separation using planar chromatography with electroosmotic flow.
PubMed:Role of cerebellar granule cell-specific GABAA receptor subtype in the differential sensitivity of [3H]ethynylbicycloorthobenzoate binding to GABA mimetics.
PubMed:Characterization of bicuculline/baclofen-insensitive (rho-like) gamma-aminobutyric acid receptors expressed in Xenopus oocytes. II. Pharmacology of gamma-aminobutyric acidA and gamma-aminobutyric acidB receptor agonists and antagonists.
PubMed:GABAergic drugs and lordosis behavior in the female rat.
PubMed:Effect of taurine and homotaurine on bile acid metabolism in dietary hyperlipidemic rats.
PubMed:Identification of extrasynaptic binding sites for [3H]GABA in peripheral nerve.
PubMed:omega-Aminosulfonic acids as depressant or excitant compounds: their effect on the behavior and electroencephalogram of young chickens.
PubMed:Effects of omega-aminosulfonic acids on lipid metabolism in dietary hyperlipidemic rats.
PubMed:Dose-conductance relationships for GABA agonists and the effect of uptake inhibitors in crayfish stretch receptor neurons.
PubMed:Detection of prion protein using a capillary electrophoresis-based competitive immunoassay with laser-induced fluorescence detection and cyclodextrin-aided separation.
PubMed:Transient isotachophoresis of highly saline trace metals under strong electroosmotic flow conditions.
PubMed:On-line coupling of capillary isotachophoresis and capillary zone electrophoresis for the determination of flavonoids in methanolic extracts of Hypericum perforatum leaves or flowers.
PubMed:Effect of glycerol-induced DNA conformational change on the separation of DNA fragments by capillary electrophoresis.
PubMed:In Situ Glutamine Synthetase Activity in a Marine Unicellular Alga (Development of a Sensitive Colorimetric Assay and the Effects of Nitrogen Status on Enzyme Activity).
PubMed:Characterization of GABAA receptor-mediated 36chloride uptake in rat brain synaptoneurosomes.
PubMed:Central receptor binding and cardiovascular effects of GABA analogues in the cat.
PubMed:Opposite effects of 2-aminoethanesulfonic acid (taurine) and aminomethanesulfonic acid on calcium ion uptake in rat retinal preparations.
PubMed:gamma-Aminobutyric acid activation of 36Cl- flux in rat hippocampal slices and its potentiation by barbiturates.
PubMed:Depolarizing action of GABA (gamma-aminobutyric acid) on myelinated fibers of peripheral nerves.
PubMed:Biphasic effects of baclofen on phrenic motoneurons: possible involvement of two types of gamma-aminobutyric acid (GABA) receptors.
PubMed:Excitability of primary afferents in feline spinal cord: taurine, homotaurine, and gamma-aminobutyric acid compared.
PubMed:An analysis of [3H]gamma-aminobutyric acid (GABA) binding in the human brain.
PubMed:Suppression of conditioned drinking by taurine and related compounds.
gaba receptor agonist; a sulfonate analog of gaba.
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