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dihydrocaffeic acid
hydrocinnamic acid, 3,4-dihydroxy-

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CAS Number: 1078-61-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:214-083-8
FDA UNII: PUH669YNEK
Nikkaji Web:J1.551.212A
Beilstein Number:2213449
MDL:MFCD00002776
XlogP3-AA:1.00 (est)
Molecular Weight:182.17550000
Formula:C9 H10 O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
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PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 399.78 °C. @ 760.00 mm Hg (est)
Flash Point: 410.00 °F. TCC ( 209.70 °C. ) (est)
logP (o/w): 0.115 (est)
Soluble in:
 water, 3.745e+004 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Dihydrocaffeic acid 98%
Odor: characteristic
Use: Dihydrocaffeic acid is a phenylpropanoid with antioxidant potential and anti-inflammatory activity.
ExtraSynthese
For experimental / research use only.
Dihydrocaffeic acid (HPLC) ≥95%
Santa Cruz Biotechnology
For experimental / research use only.
3,4-Dihydroxyhydrocinnamic acid ≥98%
Sigma-Aldrich: Aldrich
For experimental / research use only.
3,4-Dihydroxyhydrocinnamic acid 98%
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for dihydrocaffeic acid usage levels up to:
 not for fragrance use.
 
Recommendation for dihydrocaffeic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :20
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
3-(2,3-dihydroxyphenyl)propanoic acid
Chemidplus:0001078611
RTECS:MW5143500 for cas# 1078-61-1
 
References:
 3-(2,3-dihydroxyphenyl)propanoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):20
Pubchem (sid):134980449
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
Metabolomics Database:Search
KEGG (GenomeNet):C04044
HMDB (The Human Metabolome Database):HMDB00423
FooDB:FDB008857
Export Tariff Code:2918.90.4000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 beet plant
Search Trop Picture
 beet root
Search Trop Picture
 
Synonyms:
 benzenepropanoic acid, 2,3-dihydroxy-
 benzenepropanoic acid, 3,4-dihydroxy- (9CI)
2,3-dihydroxy-b-phenylproprionic acid
3,4-dihydroxyhydrocinnamic acid
3-(3,4-dihydroxyphenyl) propionic acid
3-(2,3-dihydroxyphenyl)propanoic acid
3-(2,3-dihydroxyphenyl)propionic acid
2,3-dihydroxyphenylpropionic acid
2,3-dihyrroxybenzenepropanoic acid
 hydrocaffeic acid
 hydrocinnamic acid, 3,4-dihydroxy-
 
 
Notes:
metabolite of caffeic acid. 3,4-Dihydroxyhydrocinnamic acid (or Dihydrocaffeic acid, DHCA) is a metabolite product of the hydrogenation of caffeoylquinic acids, occurring in normal human biofluids, with potent antioxidant properties. DHCA has been detected in human plasma following coffee ingestion (PMID 15607645), and is increased with some dietary sources, such as after ingestion of phenolic constituents of artichoke leaf extract. (PMID 15693705) Polyphenol-rich foods such as vegetables and fruits have been shown to significantly improve platelet function in ex vivo studies in humans. (PMID 16038718) Its antioxidant activity has been tested to reduce ferric iron in the ferric reducing antioxidant power (FRAP) assay, and it has been suggested that its catechol structure convey the antioxidant effect in plasma and in erythrocytes. (PMID 11768243) [HMDB]
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