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Category:information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.86100 to 0.86400 @ 20.00 °C.
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| Pounds per Gallon - (est).: | 7.173 to 7.198
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| Refractive Index: | 1.42000 to 1.42300 @ 20.00 °C.
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| Melting Point: | 2.00 to 4.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 102.00 to 105.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 17.184000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 77.00 °F. TCC ( 25.00 °C. )
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| logP (o/w): | 0.280 |
| Soluble in: |
| | alcohol | | | water, 1000000 mg/L @ 25 °C (exp) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 1950 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 115, Pg. 230, 1955.
oral-mouse LD50 500 mg/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BEHAVIORAL: ATAXIA
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(4), Pg. 55, 1987.
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| Dermal Toxicity: |
subcutaneous-mouse LD50 1161 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Yakugaku Zasshi. Journal of Pharmacy. Vol. 76, Pg. 181, 1956.
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| Inhalation Toxicity: |
inhalation-mouse LC50 2000 mg/m3
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BEHAVIORAL: ATAXIA
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(4), Pg. 55, 1987.
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Safety in Use Information:
| Category: | | information only not used for fragrances or flavors |
| Recommendation for 2-methyl-3-butyn-2-ol usage levels up to: | | | not for fragrance use.
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| Recommendation for 2-methyl-3-butyn-2-ol flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | but-3-yn-2-ol, 2-methyl- | | 3- | butyn-2-ol, 2-methyl- | | | dimethyl acetylenyl carbinol | | | dimethyl ethynyl carbinol | | 1,1- | dimethyl propargyl alcohol | | | dimethylacetylenylcarbinol | | | dimethylethynylcarbinol | | 1,1- | dimethylpropargyl alcohol | | 2,2- | dimethylpropargyl alcohol | | 2- | hydroxy-2-methyl-3-butyne | | 3- | methyl butynol | | 3- | methyl-1-butyn-3-ol | | 2- | methyl-2-butynol | | 3- | methyl-3-hydroxy-1-butyne | | 2- | methyl-but-3-yn-2-ol | | 2- | methylbut-3-yn-2-ol | | 3- | methylbutynol |
Articles:
| PubMed:Novel synthesis of thick wall coatings of titania supported Bi poisoned Pd catalysts and application in selective hydrogenation of acetylene alcohols in capillary microreactors. |
| PubMed:Fabrication of magnetically recoverable catalysts based on mixtures of Pd and iron oxide nanoparticles for hydrogenation of alkyne alcohols. |
| PubMed:Reactivity of Cl atom with triple-bonded molecules. An experimental and theoretical study with alcohols. |
| PubMed:Practical synthesis of aryl-2-methyl-3-butyn-2-ols from aryl bromides via conventional and decarboxylative copper-free Sonogashira coupling reactions. |
| PubMed:Influence of natural adsorbates of magnesium oxide on its reactivity in basic catalysis. |
| PubMed:An easily removable stereo-dictating group for enantioselective synthesis of propargylic amines. |
| PubMed:Detection of estrus in Indian blackbuck: behavioural, hormonal and urinary volatiles evaluation. |
| PubMed:4,4'-(4,5-dimethyl-1,2-phenylene)bis(2-methylbut-3-yn-2-ol): structural variation in vicinal dialkynols. |
| PubMed:A computational study on the role of chiral N-oxides in enantioselective Pauson-Khand reactions. |
| PubMed:Structure sensitivity of alkynol hydrogenation on shape- and size-controlled palladium nanocrystals: which sites are most active and selective? |
| PubMed:A rapid and efficient synthetic route to terminal arylacetylenes by tetrabutylammonium hydroxide- and methanol-catalyzed cleavage of 4-aryl-2-methyl-3-butyn-2-ols. |
| PubMed:Synthesis of a novel restricted access chiral stationary phase based on atom transfer radical polymerization and click chemistry for the analysis of chiral drugs in biological matrices. |
| PubMed:Basic reactivity of CaO: investigating active sites under operating conditions. |
| PubMed:Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase. |
| PubMed:Ligand accelerated indium(III)-catalyzed asymmetric alkynylation of aldehydes with 2-methyl-3-butyn-2-ol as an ethyne equivalent donor. |
| PubMed:Synthesis and cytotoxic activity of benzo[a]pyrano[3,2-h] and [2,3-i]xanthone analogues of psorospermine, acronycine, and benzo[a]acronycine. |
| PubMed:Hydride-alkenylcarbyne to alkenylcarbene transformation in bisphosphine-osmium complexes. |
| PubMed:Tandem Sonogashira coupling: an efficient tool for the synthesis of diarylalkynes. |
| PubMed:Regioselective synthesis of 6-alkyl- and 6-prenylpolyhydroxyisoflavones and 6-alkylcoumaronochromone derivatives. |
| PubMed:One step Pd(0)-catalyzed synthesis, X-ray analysis, and photophysical properties of cyclopent[hi]aceanthrylene: fullerene-like properties in a nonalternant cyclopentafused aromatic hydrocarbon. |
| PubMed:Synthesis and cytotoxic activity of benzopyranoxanthone analogues of benz. |
| PubMed:Enantioselective addition of 2-methyl-3-butyn-2-ol to aldehydes: preparation of 3-hydroxy-1-butynes |
| PubMed:Methylbutynol effectively replaces methylbutenol, a pheromone component ofIps typographus (L.) (Coleoptera: Scolytidae). |
| PubMed:2-Methyl-3-butyn-2-ol as an acetylene precursor in the Mannich reaction. A new synthesis of suicide inactivators of monoamine oxidase. |
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3D/inchi