menadione
Notes :
a synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin k2, menaquinone, after alkylation in vivo.
  • Lansdowne Chemicals
    • Lansdowne Chemicals
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      Headquarters are in Carterton, Oxfordshire encompassing all of Lansdowne's Business Units. Our Regulatory Team and Quality Control Departments are based out of Carterton. Lansdowne Aromatic's state of the art warehouse facilities are located in Cricklade, covering 12,000 square ft. We are able to offer just-in-time deliveries for our full range of products, in a variety of pack sizes. Bonded facilities are available for goods going outside of the EU.
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      Fax:+44 1993 841261
      US Voice:+1 973 886 3778
      US Fax:+1 973 346 1106
      Product(s):
      2-Methyl-1,4 Napthoquinone
       
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    • Penta International Corporation
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      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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      Product(s):
      22-90275 VITAMIN K3, Kosher
       
 
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      • Organoleptic Properties
          
  • Properties
      • Physical Properties
        Assay : 95.00 to 100.00 % 
        Food Chemicals Codex Listed :No
        Melting Point : 107.00 °C. @ 760.00 mm Hg
        Boiling Point : 304.50 °C. @ 760.00 mm Hg (est)
        Vapor Pressure :0.001000 mm/Hg @ 25.00 °C. (est)
        Flash Point : 237.00 °F. TCC ( 113.80 °C. ) (est)
        logP (o/w) : 2.200
  • Safety
      • Safety Information
        Oral/Parenteral Toxicity : 
          intraperitoneal-chicken LDLo  100 mg/kg
        Proceedings of the Society for Experimental Biology and Medicine. Vol. 43, Pg. 125, 1940.

        intraperitoneal-mouse LD50  50 mg/kg
        National Technical Information Service. Vol. AD691-490

        oral-mouse LD50  500 mg/kg
        Proceedings of the Society for Experimental Biology and Medicine. Vol. 43, Pg. 125, 1940.

        oral-rabbit LDLo  230 mg/kg
        VASCULAR: OTHER CHANGES
        Journal of Pharmacology and Experimental Therapeutics. Vol. 75, Pg. 111, 1942.

        intraperitoneal-rat LD50  75 mg/kg
        Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.

        Dermal Toxicity : 
          subcutaneous-mouse LD50 138 mg/kg
        Journal of Pharmacology and Experimental Therapeutics. Vol. 75, Pg. 111, 1942.

        Inhalation Toxicity : 
          Not determined
  • Safety in Use
      • Safety in Use Information
        Category :masking agents
        Recommendation for menadione fragrance usage levels up to :
         not for fragrance use.
        Recommendation for menadione flavor usage levels up to :
         not for flavor use.
  • Safety References
2-methylnaphthalene-1,4-dione (Click)
CAS Number : 58-27-5
ECHA EC Number :200-372-6
FDA UNII:723JX6CXY5
Beilstein Number :1908453
MDL :MFCD00001681
XlogP3 :2.20 (est)
Molecular Weight :172.18316000
Formula :C11 H8 O2
BioActivity Summary :listing
NMR Predictor :Predict
Category :masking agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information :
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2-methylnaphthalene-1,4-dione
Synonyms :
aquakay
aquinone
1,4-dhydro-1,4-dioxo-2-methylnaphthalene
1,4-dihydro-1,4-dioxo-2-methylnaphthalene
1,4-dihydro-2-methylnaphthalene-1,4-dione
hykinone
juva-K
K-vitan
kaergona
kanone
kappaxan
kappaxin
karcon
kareon
kativ-G
kayklot
kaykot
kaynone
kayquinone
koaxin
kolklot
menadion
menaphthene
menaphtone
menaquinone O
2-methyl-1,4-naphthalendione
2-methyl-1,4-naphthochinone
2-methyl-1,4-naphthodione
2-methyl-1,4-naphthoquinone
2-methylnaphthalene-1,4-dione
1,4-naphthalenedione, 2-methyl-
1,4-naphthoquinone, 2-methyl-
panosine
synkay
vitamin K3
vitamin-K3
Soluble in :
 water, 160 mg/L @ 30 °C (exp)
 water, 793.8 mg/L @ 25 °C (est)
Stability :
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