|
Category:pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless clear liquid (est) |
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.93700 @ 25.00 °C.
|
| Refractive Index: | 1.40800 @ 20.00 °C.
|
| Melting Point: | -68.00 °C. @ 760.00 mm Hg (est)
|
| Boiling Point: | 162.00 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 3.201000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 158.00 °F. TCC ( 70.00 °C. )
|
| logP (o/w): | -0.360 |
| Soluble in: |
| | water, 1.00E+06 mg/L @ 20 °C (exp) | | | water, 1.796e+005 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-mouse LD50 6000 mg/kg
BEHAVIORAL: ATAXIA
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Toksikologicheskii Vestnik. Vol. (1), Pg. 27, 1996.
oral-rat LD50 5400 mg/kg
BEHAVIORAL: ATAXIA
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Toksikologicheskii Vestnik. Vol. (1), Pg. 27, 1996.
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | pharmaceuticals / chemical synthisis |
| Recommendation for 2-methoxyethyl ether usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for 2-methoxyethyl ether flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | di(2-methoxyethyl) ether | | | diethylene glycol dimethyl ether | | | diglyme | | | dimethoxydiglycol | | | dimethyldiglycol | | | ethane, 1-methoxy-2-(2-methoxyethoxy)- | | | ethane, 2,2'-oxybis[1-methoxy- | | | ether, bis(2-methoxyethyl) | | 1- | methoxy-2-(2-methoxyethoxy)ethane | | 1,1'-oxybis(2- | methoxyethane) | | 2,2'-oxybis(1- | methoxyethane) | | bis(2- | methoxyethyl) ether | | 2- | methoxyethylether | | 2,2'-oxybis[1-( | methyloxy)ethane] | | 2,5,8- | trioxanonane |
Articles:
| PubMed:Amorphous Silicon: New Insights into an Old Material. |
| PubMed:Synergetic Role of Li(+) during Mg Electrodeposition/Dissolution in Borohydride Diglyme Electrolyte Solution: Voltammetric Stripping Behaviors on a Pt Microelectrode Indicative of Mg-Li Alloying and Facilitated Dissolution. |
| PubMed:Combinatorial discovery of cosolvent systems for production of narrow dispersion thiolate-protected gold nanoparticles. |
| PubMed:Effect of oxygenated fuels on physicochemical and toxicological characteristics of diesel particulate emissions. |
| PubMed:Characterization of a multicomponent lithium lithiate from a combined x-ray diffraction, NMR spectroscopy, and computational approach. |
| PubMed:Screening rat mesenchymal stem cell attachment and differentiation on surface chemistries using plasma polymer gradients. |
| PubMed:Solvation structure and energetics of electrolytes for multivalent energy storage. |
| PubMed:Bis{bis-[1-meth-oxy-2-(2-meth-oxy-eth-oxy)ethane-κ(3) O,O',O'']sodium} 1,1,2,2-tetra-phenyl-ethane-1,2-diide. |
| PubMed:Use of graphite as a highly reversible electrode with superior cycle life for sodium-ion batteries by making use of co-intercalation phenomena. |
| PubMed:Direct synthesis of hexagonal NaGdF₄ nanocrystals from a single-source precursor: upconverting NaGdF₄ :Yb³⁺ ,Tm³⁺ and its composites with TiO₂ for near-IR-driven photocatalysis. |
| PubMed:A facile and convenient sequential homobimetallic catalytic approach towards β-methylstyrenes. A one-pot Stille cross-coupling/isomerization strategy. |
| PubMed:Chelate effects in glyme/lithium bis(trifluoromethanesulfonyl)amide solvate ionic liquids. I. Stability of solvate cations and correlation with electrolyte properties. |
| PubMed:Source identification of high glyme concentrations in the Oder River. |
| PubMed:Magnesium(II) bis(trifluoromethane sulfonyl) imide-based electrolytes with wide electrochemical windows for rechargeable magnesium batteries. |
| PubMed:Synthesis and characterization of calcium N,N-dimethylaminodiboranates as possible chemical vapor deposition precursors. |
| PubMed:Coordination chemistry in magnesium battery electrolytes: how ligands affect their performance. |
| PubMed:Chemiluminescent 2,6-diphenylimidazo[1,2-a]pyrazin-3(7H)-ones: a new entry to Cypridina luciferin analogues. |
| PubMed:A molecular precursor approach to monodisperse scintillating CeF3 nanocrystals. |
| PubMed:Behavior of organophosphates and hydrophilic ethers during bank filtration and their potential application as organic tracers. A field study from the Oderbruch, Germany. |
| PubMed:A comprehensive study on the cell chemistry of the sodium superoxide (NaO2) battery. |
| PubMed:Dual mode single agent thermochemical ablation by simultaneous release of heat energy and acid: hydrolysis of electrophiles. |
| PubMed:Nickel-catalyzed carbon-carbon bond-forming reactions of unactivated tertiary alkyl halides: Suzuki arylations. |
| PubMed:Simultaneous determination of six hydrophilic ethers at trace levels using coconut charcoal adsorbent and gas chromatography/mass spectrometry. |
| PubMed:Molecular motion of the bis(maleonitriledithiolato)nickel trianion in solution. |
| PubMed:Nickel-catalyzed coupling reactions of alkyl electrophiles, including unactivated tertiary halides, to generate carbon-boron bonds. |
| PubMed:Synthesis and structural diversity of barium (N,N-dimethylamino)diboranates. |
| PubMed:Added-metal-free catalytic nucleophilic addition of Grignard reagents to ketones. |
| PubMed:On the control of secondary carbanion structure utilising ligand effects during directed metallation. |
| PubMed:Assessing embryonic stem cell response to surface chemistry using plasma polymer gradients. |
| PubMed:Ring-opening reactions of 1,4-diazabicyclo[2.2.2]octane (DABCO) derived quaternary ammonium salts with phenols and related nucleophiles. |
| PubMed:Ionic liquid mediated routes to polydentate oxygen-donor adducts of cerium(III) bromide. |
| PubMed:Effects of perfluorocarbon gases on the size and stability characteristics of phospholipid-coated microbubbles: osmotic effect versus interfacial film stabilization. |
| PubMed:Novel heterometal-organic complexes as first single source precursors for up-converting NaY(Ln)F4 (Ln = Yb, Er, Tm) nanomaterials. |
| PubMed:Strong fragmentation processes driven by low energy electron attachment to various small perfluoroether molecules. |
| PubMed:An X-ray and neutron reflectometry study of 'PEG-like' plasma polymer films. |
| PubMed:Acceptor (CF3)PCPH pincer reactivity with (PPh3)3Ir(CO)H. |
| PubMed:Optimizing sensitization processes in dinuclear luminescent lanthanide oligomers: selection of rigid aromatic spacers. |
| PubMed:Evaluation of different nonspecific binding blocking agents deposited inside poly(methyl methacrylate) microfluidic flow-cells. |
| PubMed:Ligand effects in the formation of tertiary carbanions from substituted tertiary aromatic amides. |
| PubMed:Eu-doped titania nanofibers: processing, thermal behaviour and luminescent properties. |
| PubMed:Dramatic thermal stability of virus-polymer conjugates in hydrophobic solvents. |
| PubMed:Synthesis and thermolytic behavior of tin(IV) formates: in search of recyclable metal-hydride systems. |
| PubMed:Structural and vibrational properties of diglyme and longer glymes. |
| PubMed:Racemization free protocol for the synthesis of N-tert-butanesulfinyl ketimines. |
| PubMed:One-step method for generating PEG-like plasma polymer gradients: chemical characterization and analysis of protein interactions. |
| PubMed:Highly volatile alkaline earth metal fluoroalkoxides. |
| PubMed:Searching for solvent cavities via electron photodetachment: the ultrafast charge-transfer-to-solvent dynamics of sodide in a series of ether solvents. |
| PubMed:Experimental investigation of engine emissions with marine gas oil-oxygenate blends. |
| PubMed:Development of a piezoelectric sensor for the detection of methamphetamine. |
| PubMed:Hydrolysis of tannic acid catalyzed by immobilized-stabilized derivatives of Tannase from Lactobacillus plantarum. |
| PubMed:Heterometallic Na-Y(Ln) trifluoroacetate diglyme complexes as novel single-source precursors for upconverting NaYF4 nanocrystals co-doped with Yb and Er/Tm ions. |
| PubMed:Fluorinated beta-diketonate diglyme lanthanide complexes as new second-order nonlinear optical chromophores: the role of f electrons in the dipolar and octupolar contribution to quadratic hyperpolarizability. |
| PubMed:Pd-catalyzed decarboxylative cross coupling of potassium polyfluorobenzoates with aryl bromides, chlorides, and triflates. |
| PubMed:Synthesis of aryl alkyl ethers by alkylation of phenols with quaternary ammonium salts. |
| PubMed:Electron spin resonance studies of the reorientational motion of Ni(mnt)2(-). |
| PubMed:Structures and unusual rearrangements of coordination adducts of MX(5) (M = Nb, Ta; X = F, Cl) with simple diethers. A crystallographic, spectroscopic, and computational study. |
| PubMed:Synthesis of the triply-bonded dimolybdenum anions [Mo(2)(eta(5)-C(5)H(5))(2)(mu-PA(2))(mu-CO)(2)](-) (A = Cy, Et, Ph, OEt): unsaturated hydride and carbyne derivatives. |
| PubMed:Plasma-assisted surface chemical patterning for single-cell culture. |
| PubMed:Synthesis and characterization of synthetically useful salts of the weakly-coordinating dianion [B12Cl12]2-. |
| PubMed:Unusual room temperature activation of 1,2-dialkoxyalkanes by niobium and tantalum pentachlorides. |
| PubMed:Molecular understanding of the UCST-type phase separation behavior of a stereocontrolled poly(N-isopropylacrylamide) in bis(2-methoxyethyl) ether. |
| PubMed:The effect of sterilization processes on the bioadhesive properties and surface chemistry of a plasma-polymerized polyethylene glycol film: XPS characterization and L929 cell proliferation tests. |
| PubMed:From 1,2-dialkoxyalkanes to 1,4-dioxanes. A transformation mediated by NbCl(5)via multiple C-O bond cleavage at room temperature. |
| PubMed:Unsaturated aldehydes as alkene equivalents in the Diels-Alder reaction. |
| PubMed:Theoretical studies on the electronic structure, charge distribution and vibrational spectra of diglyme-M(+)-AsF(6)(-) (M=Li, Na, K). |
| PubMed:Characterization of low-fouling ethylene glycol containing plasma polymer films. |
| PubMed:[Te(CN)4] versus [Te(CN)3(micro-CN)](n). |
| PubMed:The reaction mechanism for the high quantum yield of Cypridina (Vargula) bioluminescence supported by the chemiluminescence of 6-aryl-2-methylimidazo[1,2-a]pyrazin-3(7H)-ones (Cypridina luciferin analogues). |
| PubMed:Diaqua-tetra-chloridotin(IV)-diglyme (1/2). |
| PubMed:Rhodium-catalyzed decarbonylation of aldoses. |
| PubMed:Molecular motion of a nickel-bis(dithiolato) complex in solution. |
| PubMed:Structural characterization of nanocrystalline lanthanum oxyfluoride films obtained by chemical vapor deposition. |
| PubMed:Beyond the corey reaction: one-step diolefination of cyclic ketones. |
| PubMed:Cardiovascular effects of selected water-miscible solvents for pharmaceutical injections and embolization materials: a comparative hemodynamic study using a sheep model. |
| PubMed:Investigating the relationship between infrared spectra of shared protons in different chemical environments: a comparison of protonated diglyme and protonated water dimer. |
| PubMed:New structural features in heavy alkaline earth-metal chemistry--molecular heterobimetallic group 1, Ba complexes. |
| PubMed:Extraction and carrier-facilitated transport of amino acids using synthetic non-cyclic receptors through bulk liquid membrane. |
| PubMed:Synthesis, characterization, and electrocatalytic activity of PtPb nanoparticles prepared by two synthetic approaches. |
| PubMed:Investigation of fundamental transport properties and thermodynamics in diglyme-salt solutions. |
| PubMed:Electronic structure and normal vibrations of CH3(OCH2CH2)nOCH3-M+-CF3SO3- (n = 2-4, M = Li, Na, and K). |
| PubMed:Spectroscopic measurements of ionic association in solutions of LiPF6. |
| PubMed:Glyme-lithium salt phase behavior. |
| PubMed:Influence of the preparation method on the surface characteristics and activity of boron-nitride-supported noble metal catalysts. |
| PubMed:Fouling and non-fouling surfaces produced by plasma polymerization of ethylene oxide monomer. |
| PubMed:A regression spline model for developmental toxicity data. |
| PubMed:Dinuclear alkynyllanthanoid(II) dications with pentaphenylcyclopentadienyl or tri-tert-butyldiphosphacyclopentadienyl counter ions. |
| PubMed:Quantum chemical study of the interaction of the short-chain poly(oxyethylene)s CH3(OCH2CH2)mOCH3 (C1EmC1; m = 1 and 2) with a water molecule in the gas phase and in solutions. |
| PubMed:Theoretical studies on blue versus red shifts in diglyme-M+-X- (M=Li, Na, and K and X=CF3SO3, PF6, and (CF3SO2)2N)). |
| PubMed:Infrared spectra of homogeneous and heterogeneous proton-bound dimers in the gas phase. |
| PubMed:Surfactant-free synthesis and functionalization of gold nanoparticles. |
| PubMed:Direct identification and quantitative determination of costunolide and dehydrocostuslactone in the fixed oil of Laurus novocanariensis by 13C-NMR spectroscopy. |
| PubMed:Tetrasilacyclobutadiene ((t)Bu(2)MeSi)(4)Si(4): a new ligand for transition-metal complexes. |
| PubMed:Mono-N-methylation of functionalized anilines with alkyl methyl carbonates over NaY faujasites. 4. Kinetics and selectivity. |
| PubMed:Comparison of cellulose extraction methods for analysis of stable-isotope ratios of carbon and oxygen in plant material. |
| PubMed:Three 1,2,4-triazole derivatives containing substituted benzyl and benzylamino groups. |
| PubMed:Synthesis and characterisation of cyclopentadienyl complexes of barium: precursors for atomic layer deposition of BaTiO3. |
| PubMed:A new type of sample tube for reducing convection effects in PGSE-NMR measurements of self-diffusion coefficients of liquid samples. |
| PubMed:Thermodynamically controlled synthesis of amide bonds catalyzed by highly organic solvent-resistant penicillin acylase derivatives. |
| PubMed:Triamidotriazacyclononane complexes of group 3 metals. Synthesis and crystal structures. |
| PubMed:Multisite catalysis: a mechanistic study of beta-lactone synthesis from epoxides and CO--insights into a difficult case of homogeneous catalysis. |
| PubMed:Functionalized arylzinc compounds in ethereal solvent: direct synthesis from aryl iodides and zinc powder and application to Pd-catalyzed reaction with allylic halides. |
| PubMed:Comparison of vehicle exhaust emissions from modified diesel fuels. |
| PubMed:3,3-difluoro-1-iodocyclopropenes: a simple synthesis and their reactions. |
| PubMed:Li+ cation coordination in [Li2(CF3SO3)2(diglyme)] and [Li3(C2F3O2)3(diglyme)]. |
| PubMed:A new synthetic route to boron-10 enriched pentaborane(9) from boric acid and its conversion to anti-(10)B(18)H(22). |
| PubMed:Sequential photostimulated reactions of trimethylstannyl anions with aromatic compounds followed by palladium-catalyzed cross-coupling processes. |
| PubMed:Iodine-containing cellulose mixed esters as radiopaque polymers for direct embolization of cerebral aneurysms and arteriovenous malformations. |
| PubMed:Monitoring method for airborne glymes and its application in fuel exhaust emission measurement. |
| PubMed:Treatment of diglyme containing wastewater by advanced oxidation--process design and optimisation. |
| PubMed:Synthesis and Properties of Polyether Adducts of Hexafluoropentanedionatosilver(I). |
| PubMed:Synthesis and Characterization of Dimeric, Trimeric, and Tetrameric Gallophosphonates and Gallophosphates. |
| PubMed:Preparation of starch and other carbon fractions from higher plant leaves for stable carbon isotope analysis. |
| PubMed:The pi complexation of alkali and alkaline earth ions by the use of meso-octaalkylporphyrinogen and aromatic hydrocarbons. |
| PubMed:Dechlorination of polychlorobiphenyls using NaBH(4) and NaBH(4)/LiCl at 120-310 degrees C in glyme solvents. |
| PubMed:Comparative hemolytic activity of undiluted organic water-miscible solvents for intravenous and intra-arterial injection. |
| PubMed:Organic solvents for pharmaceutical parenterals and embolic liquids: a review of toxicity data. |
| PubMed:Transglycosylation by Streptococcus mutans GS-5 glucosyltransferase-D: acceptor specificity and engineering of reaction conditions. |
| PubMed:Effects of medium on decarboxylation kinetics: 3-carboxybenzisoxazoles and their potential use as environmental probes in biochemistry. |
| PubMed:A rapid and simple method for processing wood to crude cellulose for analysis of stable carbon isotopes in tree rings. |
| PubMed:Skin absorption in vitro of glycol ethers. |
| PubMed:Subchronic inhalation toxicity of diglyme. |
| PubMed:Developmental toxicity of diglyme by inhalation in the rat. |
| PubMed:Preparation and NMR Spectra of Difluoromethylated Silver(I) and Silver(III) Compounds. Structure of [PNP][Ag(CF(2)H)(4)]. |
| PubMed:Bivariate modelling of clustered continuous and ordered categorical outcomes. |
| PubMed:Preparation and NMR Spectra of the (Trifluoromethyl)argentates(III) [Ag(CF(3))(n)X(4-n)](-), with X = CN (n = 1-3), CH(3), C&tbd1;CC(6)H(11), Cl, Br (n = 2, 3), and I (n = 3), and of Related Silver(III) Compounds. Structures of [PPh(4)][trans-Ag(CF(3))(2)(CN)(2)] and [PPh(4)][Ag(CF(3))(3)(CH(3))]. |
| PubMed:Efficient Synthesis of 1-Amino-2-naphthalenecarboxylic Acid Derivatives via a Sequential Michael Addition/Enolate-Nitrile Coupling Route and Its Application to Facile Preparation of 9-Amino Analogues of Arylnaphthofuranone Lignans. |
| PubMed:Occupational dermatoses from exposure to epoxy resin compounds in a ski factory. |
| PubMed:Alkali Metal Bis(o-anisyl)phosphides: Characterization of MP(C(6)H(4)OMe-o)(2) (M = Li, Na) and Crystal Structure of a Sodium Secondary Organophosphide. |
| PubMed:The role of a liquid matrix in controlling FAB-induced fragmentation. |
| PubMed:Infrared multiple photon dissociation in the quadrupole ion trap via a multipass optical arrangement. |
| PubMed:Quantitation of formaldehyde, acetaldehyde, and acetone in sidestream cigarette smoke by high-performance liquid chromatography. |
| PubMed:Comparative metabolism of bis(2-methoxyethyl) ether by rat and human hepatic microsomes: formation of 2-methoxyethanol. |
| PubMed:Statistical model for fetal death, fetal weight, and malformation in developmental toxicity studies. |
| PubMed:Real-time measurement of sub-PPM concentrations of airborne chemicals in semiconductor manufacturing. |
| PubMed:Comparative metabolism of bis(2-methoxyethyl)ether in isolated rat hepatocytes and in the intact rat: effects of ethanol on in vitro metabolism. |
| PubMed:The developmental toxicity of diethylene and triethylene glycol dimethyl ethers in rabbits. |
| PubMed:Synthesis and characterization of highly substituted deoxyfluorocellulose acetate. |
| PubMed:Mortality of employees in plants manufacturing 4,4'-bipyridyl. |
| PubMed:[Toxicity of bis(2-methoxyethyl)ether of sebacic acid]. |
| PubMed:Bis(2-methoxyethyl) ether: metabolism and embryonic disposition of a developmental toxicant in the pregnant CD-1 mouse. |
| PubMed:Comparative testicular toxicity of bis(2-methoxyethyl) ether and 2-methoxyethanol in rats. |
| PubMed:Testicular effects of bis(2-methoxyethyl) ether in the adult male rat. |
| PubMed:The role of enzyme induction on metabolite formation of bis(2-methoxyethyl) ether in the rat. |
| PubMed:Characterization of a developmental toxicity dose-response model. |
| PubMed:Metabolism of bis(2-methoxyethyl) ether in the adult male rat: evaluation of the principal metabolite as a testicular toxicant. |
| PubMed:Relative potency of four ethylene glycol ethers for induction of paw malformations in the CD-1 mouse. |
| PubMed:The developmental toxicity of diethylene glycol dimethyl ether in mice. |
| PubMed:Evaluation of 60 chemicals in a preliminary developmental toxicity test. |
| PubMed:Developmental toxicity of nine selected compounds following prenatal exposure in the mouse: naphthalene, p-nitrophenol, sodium selenite, dimethyl phthalate, ethylenethiourea, and four glycol ether derivatives. |
| PubMed:Genotoxicity of glycol ethers. |
| PubMed:Experimental studies on toxicity of ethylene glycol alkyl ethers in Japan. |
| PubMed:Genetic effects of 2-methoxyethanol and bis(2-methoxyethyl)ether. |
| PubMed:Reproductive toxicity of the glycol ethers. |
| PubMed:Stability-indicating colorimetric assay for indicine N-oxide using TLC. |
|
3D/inchi