EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes


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CAS Number: 149-30-4Picture of molecule3D/inchi
Other(deleted CASRN):112242-83-8
ECHA EINECS - REACH Pre-Reg:205-736-8
Nikkaji Web:J2.552F
Beilstein Number:119484
XlogP3:2.40 (est)
Molecular Weight:167.25385000
Formula:C7 H5 N S2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
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Physical Properties:
Appearance:pale yellow to tan crystalline powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 120 mg/L @ 24C (exp)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
BOC Sciences
For experimental / research use only.
2-Mercaptobenzothiazole 98%
Charkit Chemical
Glentham Life Sciences
Santa Cruz Biotechnology
For experimental / research use only.
Shiva Chemicals and Pharmaceuticals
Sigma-Aldrich: Aldrich
For experimental / research use only.
2-Mercaptobenzothiazole 97%
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 100 mg/kg
National Technical Information Service. Vol. AD277-689

oral-mouse LD50 1158 mg/kg
Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. Vol. 36(1-4), Pg. 10, 1989.

oral-quail LD50 > 2150 mg/kg
National Technical Information Service. Vol. OTS0535428

intraperitoneal-rat LD50 300 mg/kg
Medycyna Pracy. Industrial Medicine. Vol. 16, Pg. 35, 1965.

oral-rat LD50 100 mg/kg
International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.

Dermal Toxicity:
skin-rabbit LD50 > 7940 mg/kg
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 62, 1990.

Inhalation Toxicity:
inhalation-rat LC50 > 1270 mg/m3
United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-1190-0987S

Safety in Use Information:
information only not used for fragrances or flavors
Recommendation for 2-mercaptobenzothiazole usage levels up to:
 not for fragrance use.
Recommendation for 2-mercaptobenzothiazole flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
Daily Med:search
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA Substance Registry Services (TSCA):149-30-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :697993
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
EPA/NOAA CAMEO:hazardous materials
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:149-30-4
Pubchem (cid):697993
Pubchem (cas):149-30-4
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
UM BBD:Search
KEGG (GenomeNet):C14437
HMDB (The Human Metabolome Database):HMDB30524
Export Tariff Code:2934.20.1500
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
 accelerator M
 benzothiazole, mercapto-
 vulkacit M


PubMed:Electrochemical characterization of in situ functionalized gold organosulfur self-assembled monolayer with conducting polymer and carbon nanotubes for determination of rutin.
PubMed:Structural and inhibition analysis of novel sulfur-rich 2-mercaptobenzothiazole and 1,2,3-triazole ligands against Mycobacterium tuberculosis DprE1 enzyme.
PubMed:Two-shell structured PMAA@CeO2 nanocontainers loaded with 2-mercaptobenzothiazole for corrosion protection of damaged epoxy coated AA 2024-T3.
PubMed:Quaternized and Thiazole-Functionalized Free Radical-Generating Organometallic Dendrimers as Antimicrobial Platform against Multidrug-Resistant Microorganisms.
PubMed:Solid phase extraction of trace amounts of cadmium(II) ions in water and food samples using iron magnetite nanoparticles modified by sodium dodecyl sulfate and 2-mercaptobenzothiazole.
PubMed:Antimicrobial activity of 2-mercaptobenzothiazole released from environmentally friendly nanostructured layered double hydroxides.
PubMed:A simultaneous disulfide bond cleavage, N,S-bialkylation/N-protonation and self-assembly reaction: syntheses, structures and properties of two hybrid iodoargentates with thiazolyl-based heterocycles.
PubMed:Extract from Maize (Zea mays L.): Antibacterial Activity of DIMBOA and Its Derivatives against Ralstonia solanacearum.
PubMed:A survey on the effects of ultrasonic irradiation, reaction time and concentration of initial reagents on formation of kinetically or thermodynamically stable copper(I) metal-organic nanomaterials.
PubMed:Triplet state formation and quenching dynamics of 2-mercaptobenzothiazole in solution.
PubMed:Microaerobic degradation of 2-Mercaptobenzothiazole present in industrial wastewater.
PubMed:New specific and sensitive biomonitoring methods for chemicals of emerging health relevance.
PubMed:The quality of sildenafil active substance of illegal source.
PubMed:Gamma irradiation of 2-mercaptobenzothiazole aqueous solution in the presence of persulfate.
PubMed:Adsorption of Heavy Metal Ions from Aqueous Solutions by Bentonite Nanocomposites.
PubMed:Tailoring nanoarchitectonics to control the release profile of payloads.
PubMed:Synergetic enhancement of gold nanoparticles and 2-mercaptobenzothiazole as highly-sensitive sensing strategy for tetrabromobisphenol A.
PubMed:Evaluating the toxic potential of benzothiazoles with the rainbow trout cell lines, RTgill-W1 and RTL-W1.
PubMed:Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling.
PubMed:Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part I: Fathead minnow.
PubMed:Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part II: Zebrafish.
PubMed:Plant Assimilation Kinetics and Metabolism of 2-Mercaptobenzothiazole Tire Rubber Vulcanizers by Arabidopsis.
PubMed:[A Study of 2-Mercaptobenzothiazole (2-MBT) and HBM values for 2-MBT in the urine of adults and children: Opinion of the "Human Biomonitoring" Commission of the German Federal Environment Agency].
PubMed:Synthesis and anticandidal evaluation of new benzothiazole derivatives with hydrazone moiety.
PubMed:Tautomeric conversion, vibrational spectra, and density functional studies on peripheral sulfur derivatives of benzothiazole and benzothiazoline isomers.
PubMed:Green in-situ synthesized silver nanoparticles embedded in bacterial cellulose nanopaper as a bionanocomposite plasmonic sensor.
PubMed:Resonance Rayleigh scattering method for determination of 2-mercaptobenzothiazole using gold nanoparticles probe.
PubMed:Hydroboration of Alkynes with Zwitterionic Ruthenium-Borate Complexes: Novel Vinylborane Complexes.
PubMed:In Vitro, Ex Vivo, and In Vivo Determination of Thyroid Hormone Modulating Activity of Benzothiazoles.
PubMed:Imaging mass spectrometry increased resolution using 2-mercaptobenzothiazole and 2,5-diaminonaphtalene matrices: application to lipid distribution in human colon.
PubMed:Development of laser desorption imaging mass spectrometry methods to investigate the molecular composition of latent fingermarks.
PubMed:Synthesis and antimicrobial activity of novel structural hybrids of benzofuroxan and benzothiazole derivatives.
PubMed:Rapid and sensitive LC-MS-MS determination of 2-mercaptobenzothiazole, a rubber additive, in human urine.
PubMed:Chemical allergens stimulate human epidermal keratinocytes to produce lymphangiogenic vascular endothelial growth factor.
PubMed:Matrix coating assisted by an electric field (MCAEF) for enhanced tissue imaging by MALDI-MS.
PubMed:Chemistry of diruthenium and dirhodium analogues of pentaborane(9): synthesis and characterization of metal n,s-heterocyclic carbene and B-agostic complexes.
PubMed:Hydride generation atomic absorption spectrometric determination of bismuth after separation and preconcentration with modified alumina.
PubMed:Reply to comments on "Adsorption of 2-mercaptobenzothiazole from aqueous solution by organo-bentonite" by Yuhshan Ho.
PubMed:Comments on "Adsorption of 2-mercaptobenzothiazole from aqueous solution by organo-bentonite" by P. Jing, M.H. Hou, P. Zhao, X.Y. Tang, H.F. Wan.
PubMed:Assessment of the allergEAZE(®) patch test compared to other conventional allergens.
PubMed:A series of cobalt and nickel clusters based on thiol-containing ligands accompanied by in situ ligand formation.
PubMed:Photodegradation of 2-mercaptobenzothiazole and 1,2,3-benzotriazole corrosion inhibitors in aqueous solutions and organic solvents.
PubMed:Tire tread wear particles in ambient air--a previously unknown source of human exposure to the biocide 2-mercaptobenzothiazole.
PubMed:Novel Ru(III) Complexes with Some Benzothiazole Derivatives: Synthesis, Physicochemical and Pharmacological Investigations.
PubMed:Extremely sensitive sandwich assay of kanamycin using surface-enhanced Raman scattering of 2-mercaptobenzothiazole labeled gold@silver nanoparticles.
PubMed:Sulfur rich 2-mercaptobenzothiazole and 1,2,3-triazole conjugates as novel antitubercular agents.
PubMed:Removal of the 2-mercaptobenotiazole from model wastewater by ozonation.
PubMed:Application of the SOS/umu test and high-content in vitro micronucleus test to determine genotoxicity and cytotoxicity of nine benzothiazoles.
PubMed:Synthesis, characterization, and binding properties towards CT-DNA and lipoxygenase of mixed-ligand silver(I) complexes with 2-mercaptothiazole and its derivatives and triphenylphosphine.
PubMed:Development of a thyroperoxidase inhibition assay for high-throughput screening.
PubMed:Concomitant patch test reactions to mercapto mix and mercaptobenzothiazole: retrospective analysis from the North American Contact Dermatitis Group, 1994-2008.
PubMed:Adsorption of 2-mercaptobenzothiazole from aqueous solution by organo-bentonite.
PubMed:Synthesis and Biological Evaluation of Some Novel 3,5-Disubstituted-1,2,4-triazole Incorporated 2-Mercaptobenzothiazoles.
PubMed:Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat.
PubMed:Solid phase extraction-preconcentration and high performance liquid chromatographic determination of 2-mercapto-(benzothiazole, benzoxazole and benzimidazole) using copper oxide nanoparticles.
PubMed:Hydroxyflavones as a new family of matrices for MALDI tissue imaging.
PubMed:An epidermal equivalent assay for identification and ranking potency of contact sensitizers.
PubMed:Using 2-mercaptobenzothiazole as a nitrogen and sulfur precursor to synthesize highly active Co-N-S/C electrocatalysts for oxygen reduction.
PubMed:Self-healing coatings based on halloysite clay polymer composites for protection of copper alloys.
PubMed:Electrochemical method for the synthesis of disulfides of 2-(benzo[d]thiazol(or oxazol)-2-ylamino)-5-morpholinobenzenethiol.
PubMed:Surface analysis of lipids by mass spectrometry: more than just imaging.
PubMed:Biological activities of 2-mercaptobenzothiazole derivatives: a review.
PubMed:Influence of embedded nanocontainers on the efficiency of active anticorrosive coatings for aluminum alloys part II: influence of nanocontainer position.
PubMed:Electrochemical synthesis based on the oxidation of 1-(4-(4-hydroxyphenyl)piperazin-1-yl)ethanone in the presence of nucleophiles.
PubMed:Inhibition of the thyroid hormone pathway in Xenopus laevis by 2-mercaptobenzothiazole.
PubMed:NCTC 2544 and IL-18 production: a tool for the identification of contact allergens.
PubMed:Cytotoxic and anticancer effects of the triorganotin compound [(C₆H₅)₃Sn(cmbzt)]: an in vitro, ex vivo and in vivo study.
PubMed:Synthesis and structural characterization of new divanada- and diniobaboranes containing chalcogen atoms.
PubMed:Influence of embedded nanocontainers on the efficiency of active anticorrosive coatings for aluminum alloys part I: influence of nanocontainer concentration.
PubMed:Allergic contact dermatitis probably caused by mercaptobenzothiazole in thermal undergarments.
PubMed:Electropolymerized surface ion imprinting films on a gold nanoparticles/single-wall carbon nanotube nanohybrids modified glassy carbon electrode for electrochemical detection of trace mercury(II) in water.
PubMed:Synthesis of novel 2-mercapto benzothiazole and 1,2,3-triazole based bis-heterocycles: their anti-inflammatory and anti-nociceptive activities.
PubMed:Rapid characterization of N-linked glycosylation site using non-specific protease digestion of gel-separated glycoproteins and matrix-assisted laser desorption/ionization tandem time-of-flight mass spectrometry.
PubMed:Silica nanocontainers for active corrosion protection.
PubMed:Fast and efficient removal of mercury from water samples using magnetic iron oxide nanoparticles modified with 2-mercaptobenzothiazole.
PubMed:Sublimation of new matrix candidates for high spatial resolution imaging mass spectrometry of lipids: enhanced information in both positive and negative polarities after 1,5-diaminonapthalene deposition.
PubMed:Simultaneous determination of ultra trace amounts of lead and cadmium in food samples by adsorptive stripping voltammetry.
PubMed:Benzothiazole toxicity assessment in support of synthetic turf field human health risk assessment.
PubMed:A comparative study on toxicity identification of industrial effluents using Daphnia magna.
PubMed:Imaging mass spectrometry detection of gangliosides species in the mouse brain following transient focal cerebral ischemia and long-term recovery.
PubMed:Experience with local lymph node assay performance standards using standard radioactivity and nonradioactive cell count measurements.
PubMed:In situ STM evidence for the adsorption geometry of three N-heteroaromatic thiols on Au(111).
PubMed:Synthesis of 2-mercaptobenzothiazoles via DBU-promoted tandem reaction of o-haloanilines and carbon disulfide.
PubMed:Identification of benzothiazole derivatives and polycyclic aromatic hydrocarbons as aryl hydrocarbon receptor agonists present in tire extracts.
PubMed:Electrochemical sensing of acyclovir at a gold electrode modified with 2-mercaptobenzothiazole-[5,10,15,20-tetrakis-(3-methoxy-4-hydroxyphenyl)porphyrinato]copper(II).
PubMed:Stripping voltammetric detection of mercury(II) based on a surface ion imprinting strategy in electropolymerized microporous poly(2-mercaptobenzothiazole) films modified glassy carbon electrode.
PubMed:Soybean peroxidase-catalyzed removal of an aromatic thiol, 2-mercaptobenzothiazole, from water.
PubMed:Allergic contact dermatitis to synthetic rubber gloves: changing trends in patch test reactions to accelerators.
PubMed:Biotransformation of benzothiazole derivatives by the Pseudomonas putida strain HKT554.
PubMed:Preparation of 2-mercaptobenzothiazole-labeled immuno-Au aggregates for SERS-based immunoassay.
PubMed:A case of severe psoriasis with an apparent incomplete response to anti-tumour necrosis factor alpha treatment.
PubMed:Leachables from saline-containing IV bags can alter therapeutic protein properties.
PubMed:[Total analysis of organic rubber additives].
PubMed:Cytotoxicity, apoptosis and study of the DNA-binding properties of bi- and tetranuclear gallium(III) complexes with heterocyclic thiolato ligands.
PubMed:The European baseline series in Lithuania: results of patch testing in consecutive adult patients.
PubMed:A vapor sensor array using multiple localized surface plasmon resonance bands in a single UV-vis spectrum.
PubMed:Significant sensitivity improvements by matrix optimization: a MALDI-TOF mass spectrometric study of lipids from hen egg yolk.
PubMed:A novel hydrophobic task specific ionic liquid for the extraction of Cd(II) from water and food samples as applied to AAS determination.
PubMed:Study of matrix additives for sensitive analysis of lipid A by matrix-assisted laser desorption ionization mass spectrometry.
PubMed:Structural properties, cytotoxicity, and anti-inflammatory activity of silver(I) complexes with tris(p-tolyl)phosphine and 5-chloro-2-mercaptobenzothiazole.
PubMed:Solid phase extraction of cadmium on 2-mercaptobenzothiazole loaded on sulfur powder in the medium of ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate and cold vapor generation-atomic absorption spectrometric determination.
PubMed:N-nitrosamines as "special case" leachables in a metered dose inhaler drug product.
PubMed:Structural motifs and biological studies of new antimony(III) iodide complexes with thiones.
PubMed:Synthesis and biological evaluation of 2-mercapto-1,3-benzothiazole derivatives with potential antimicrobial activity.
PubMed:Modification of chloromethylated polystyrene with 2-mercabtobenzothiazole for application as a new sorbent for preconcentration and determination of Ag+ from different matrices.
PubMed:Elimination of sludge odor by oxidizing sulfur-containing compounds with ferrate(VI).
PubMed:Molecular structure, IR spectra of 2-mercaptobenzothiazole and 2-mercaptobenzoxazole by density functional theory and ab initio Hartree-Fock calculations.
PubMed:Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens.
PubMed:Appraisal of the sensitising potential of orally and dermally administered mercaptobenzothiazole by a biphasic protocol of the local lymph node assay.
PubMed:Rhenium(I) tricarbonyl complexes with poly(azolyl)borates generated in situ from an organometallic precursor containing the B-H...Re coordination motif.
PubMed:Expression of surface markers on the human monocytic leukaemia cell line, THP-1, as indicators for the sensitizing potential of chemicals.
PubMed:New antimony(III) bromide complexes with thioamides: synthesis, characterization, and cytostatic properties.
PubMed:Cancer risks in chemical production workers exposed to 2-mercaptobenzothiazole.
PubMed:Alternative procedures for analysis of lipid A modification with phosphoethanolamine or aminoarabinose.
PubMed:Application of 2-mercaptobenzothiazole self-assembled monolayer on polycrystalline gold electrode as a nanosensor for determination of Ag(I).
PubMed:Indirect extraction-spectrophotometric determination of 2-(thiocyanomethylthiol)benzothiazole in chrome tanning liquors after its breakdown to 2-mercaptobenzothiazole.
PubMed:Chelating 2-mercaptobenzothiazole loaded resin. Application to the separation of inorganic and alkylmercury species for their atomic absorption spectrometry determination in natural waters.
PubMed:Profiling and imaging of lipids on brain and liver tissue by matrix-assisted laser desorption/ ionization mass spectrometry using 2-mercaptobenzothiazole as a matrix.
PubMed:Structural motifs of diiodine complexes with amides and thioamides.
PubMed:Bladder cancer risks in workers manufacturing chemicals for the rubber industry.
PubMed:Mercaptobenzothiazole allergenicity-role of the thiol group.
PubMed:The oxidative degradation of 2-mercaptobenzothiazole at the interface of beta-MnO2 and water.
PubMed:Photodegradation of 2-mercaptobenzothiazole in the gamma-Fe(2)O(3)/oxalate suspension under UVA light irradiation.
PubMed:Simultaneous square wave voltammetric determination of 2-mercaptobenzothiazole and 2-mercaptobenzoxazole by partial least squares method in water samples.
PubMed:Oxidation of 2-mercaptobenzothiazole in latex gloves and its possible haptenation pathway.
PubMed:Pressure-tuning Raman spectra of diiodine thioamide compounds: models for antithyroid drug activity.
PubMed:Comparison of the adsorption orientation for 2-mercaptobenzothiazole and 2-mercaptobenzoxazole by SERS spectroscopy.
PubMed:Fmoc-2-mercaptobenzothiazole, for the introduction of the Fmoc moiety free of side-reactions.
PubMed:Zebrafish as a new model for phenotype-based screening of melanogenic regulatory compounds.
PubMed:Synthesis, structural characterization, and biological studies of six- and five-coordinate organotin(IV) complexes with the thioamides 2-mercaptobenzothiazole, 5-chloro-2-mercaptobenzothiazole, and 2-mercaptobenzoxazole.
PubMed:Matrix-assisted laser desorption/ionization-mass spectrometry of hydrophobic proteins in mixtures using formic acid, perfluorooctanoic acid, and sorbitol.
PubMed:High-performance liquid chromatography analysis of rubber allergens in protective gloves used in health care.
PubMed:Structural identification and characterization of impurities in ceftizoxime sodium.
PubMed:Predicting the efficiencies of 2-mercaptobenzothiazole collectors used as chelating agents in flotation processes: a density-functional study.
PubMed:Preparation of 2-mercaptobenzothiazole-derivatized mesoporous silica and removal of Hg(ii) from aqueous solution.
PubMed:MIP-1beta, a novel biomarker for in vitro sensitization test using human monocytic cell line.
PubMed:Rubber additives induce oxidative stress in rainbow trout.
PubMed:FTIR, Raman spectra and ab initio calculations of 2-mercaptobenzothiazole.
PubMed:In vitro induction of polyploidy and chromatid exchanges by culture medium extracts of natural rubbers compounded with 2-mercaptobenzothiazole as a positive control candidate for genotoxicity tests.
PubMed:Survey of sulfur-containing rubber accelerator levels in latex and nitrile exam gloves.
PubMed:Human health risk assessment of 2-mercaptobenzothiazole in drinking water.
PubMed:A wood preservative metabolite in river water.
PubMed:Comparative aquatic toxicity evaluation of 2-(thiocyanomethylthio)benzothiazole and selected degradation products using Ceriodaphnia dubia.
PubMed:Determination of 2-mercaptobenzothiazole (MBT) in tannery wastewater by high performance liquid chromatography with amperometric detection.
PubMed:Determination of benzothiazoles from complex aqueous samples by liquid chromatography-mass spectrometry following solid-phase extraction.
PubMed:Occurrence of benzothiazoles in municipal wastewater and their fate in biological treatment.
PubMed:Metabolism of 2-mercaptobenzothiazole by Rhodococcus rhodochrous.
PubMed:Homolytic cleavage and aggregation processes in cyclopentadienylchromium chemistry.
PubMed:Common shoe allergens undetected by commercial patch-testing kits: dithiodimorpholine and isocyanates.
PubMed:Migration of N-nitrosamines, N-nitrosatable substances and 2-mercaptobenzthiazol from baby bottle teats and soothers: a Dutch retail survey.
PubMed:Synthesis, structural characterization and in vitro cytotoxicity of organotin(IV) derivatives of heterocyclic thioamides, 2-mercaptobenzothiazole, 5-chloro-2-mercaptobenzothiazole, 3-methyl-2-mercaptobenzothiazole and 2-mercaptonicotinic acid.
PubMed:Wire-coated silver(I) ion-selective electrode based on 2-mercaptobenzothiazole (MBT) ionophore: application to the determination of silver in real samples.
PubMed:Development and application of an LC-MS method to determine possible migration of mercaptobenzothiazole, benzothiazole and related vulcanization residues from rubber used in contact with food and drink.
PubMed:Studies in polyphenol chemistry and bioactivity. 4.(1) Synthesis of trimeric, tetrameric, pentameric, and higher oligomeric epicatechin-derived procyanidins having all-4beta,8-interflavan connectivity and their inhibition of cancer cell growth through cell cycle arrest.
PubMed:Evaluation of CD86 expression and MHC class II molecule internalization in THP-1 human monocyte cells as predictive endpoints for contact sensitizers.
PubMed:Determination of the sensitising activity of the rubber contact sensitisers TMTD, ZDMC, MBT and DEA in a modified local lymph node assay and the effect of sodium dodecyl sulfate pretreatment on local lymph node responses.
PubMed:Optimization of the simultaneous batch determinations of Bi(III), Hg(II) and Cu(II) at an epoxy-graphite electrode bulk modified with 2-mercaptobenzothiazole.
PubMed:Microbial transformations of 2-substituted benzothiazoles.
PubMed:[Residual chemicals in natural rubber products for food contact use].
PubMed:Modified short-term guinea pig sensitization tests for detecting contact allergens as an alternative to the conventional test.
PubMed:Synthesis and biological studies of some benzopyran.
PubMed:Exploring the limits of bacterial identification by intact cell-mass spectrometry.
PubMed:A rapid procedure to prepare cefotaxime.
PubMed:A quantitative method for assessing the sensitizing potency of low molecular weight chemicals using a local lymph node assay: employment of a regression method that includes determination of the uncertainty margins.
PubMed:A further cohort study of workers employed at a factory manufacturing chemicals for the rubber industry, with special reference to the chemicals 2-mercaptobenzothiazole (MBT), aniline, phenyl-beta-naphthylamine and o-toluidine.
PubMed:Mortalities of workers at the Nitro plant with exposure to 2-mercaptobenzothialzole.
PubMed:Assessment of in vivo chromosomal aberrations--potency of zinc mercapto benzo thiazole.
PubMed:Ion/Surface Reactions at Monolayers in Solution: A Combined Surface Enhanced Raman-X-Ray Photoelectron Spectroscopic Investigation of the Chemical Modification of a 2-Mercaptobenzothiazole Monolayer on Polycrystalline Au Films.
PubMed:Contact allergy to mercaptobenzothiazole in a bank clerk from a wet sponge.
PubMed:Role of glutamate 144 and glutamate 164 in the catalytic mechanism of enoyl-CoA hydratase.
PubMed:Triorganotin compounds as antimicrobial agents.
PubMed:The effect of solvent and matrix combinations on the analysis of bacteria by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry.
PubMed:Matrix optimization for matrix-assisted laser desorption/ionization mass spectrometry of oligosaccharides from human milk.
PubMed:Derivative spectrophotometric determination of the triethylammonium salt of cefotaxime in presence of related compounds from the synthesis.
PubMed:A Combined Surface-Enhanced Raman-X-Ray Photoelectron Spectroscopic Study of 2-mercaptobenzothiazole Monolayers on Polycrystalline Au and Ag Films.
PubMed:Initial transformations in the biodegradation of benzothiazoles by Rhodococcus isolates.
PubMed:Elimination reactions in the medium-chain acyl-CoA dehydrogenase: bioactivation of cytotoxic 4-thiaalkanoic acids.
PubMed:Structural characterization of peptidoglycan muropeptides by matrix-assisted laser desorption ionization mass spectrometry and postsource decay analysis.
PubMed:Extraction of mercaptobenzothiazole compounds from rubber products.
PubMed:Cathodic stripping voltammetric determination of 2-mercaptobenzothiazole using the catalytic cobalt peak.
PubMed:Determination of urinary 2-mercaptobenzothiazole (2-MBT), the main metabolite of 2-(thiocyanomethylthio)benzothiazole (TCMTB) in humans and rats.
PubMed:The guinea pig maximization test--with a multiple dose design.
PubMed:[2-mercaptobenzothiazole in baby pacifiers].
PubMed:Sorption and preconcentration of some heavy metals by 2-mercaptobenzothiazole-clay.
PubMed:Efficacy of 6-amino-2-n-pentylthiobenzothiazole on Trichophyton in vitro and in vivo.
PubMed:Metabolism of 2-thiobenzothiazoles in the rat. Urinary, fecal and biliary metabolites of 2-benzothiazyl sulfenamides.
PubMed:[The toxic hygiene problems of workers in the Dinamik automobile tire plant in Sofia].
PubMed:Toxicity of 2-mercaptobenzothiazole towards bacterial growth and respiration.
PubMed:2-Mercaptobenzothiazole degradation in laboratory fed-batch systems.
PubMed:Allergic contact dermatitis in HIV-positive patients.
PubMed:Controversy over ionic and nonionic radiopaque contrast media.
PubMed:Skin elicitation threshold of ethylbutyl thiourea and mercaptobenzothiazole with relative leaching from sensitizing products.
PubMed:Identification of causative chemicals of allergic contact dermatitis using a combination of patch testing in patients and chemical analysis. Application to cases from rubber footwear.
PubMed:A laser Raman spectroscopic study on the interaction of alkylmercury with thiol and sulfur-containing compounds.
PubMed:Mortality study of workers employed at a plant manufacturing chemicals for the rubber industry: 1955-86.
PubMed:Mortality experience of employees exposed to 2-mercaptobenzothiazole at a chemical plant in Nitro, West Virginia.
PubMed:Anti-Candida activity of four antifungal benzothiazoles.
PubMed:Parameters affecting the degradation of benzothiazoles and benzimidazoles in activated sludge systems.
PubMed:Footwear dermatitis.
PubMed:Carcinogenicity of azathioprine: an S-AR investigation.
PubMed:Evaluation of contact sensitivity of rubber chemicals using the murine local lymph node assay.
PubMed:Results with OECD recommended positive control sensitizers in the maximization, Buehler and local lymph node assays.
PubMed:HPLC determination of rubber septum contaminants in the iodinated intravenous contrast agent (sodium iothalamate).
PubMed:Stability of the mercaptobenzothiazole compounds.
PubMed:High-performance liquid chromatography-fluorescence assay of pyruvic acid to determine cysteine conjugate beta-lyase activity: application to S-1,2-dichlorovinyl-L-cysteine and S-2-benzothiazolyl-L-cysteine.
PubMed:A new catalytic polarographic system for determination of trace amounts of tungsten.
PubMed:[The use of the sauna for disease prevention in the workers of enterprises with chemical and physical occupational hazards].
PubMed:[Pharmacokinetics of 2-mercaptobenzothiazole in animals].
PubMed:Medical rubber anaphylaxis.
PubMed:Allergic contact dermatitis from mercaptobenzothiazole in a releasing fluid.
PubMed:In vivo metabolites of S-(2-benzothiazolyl)-L-cysteine as markers of in vivo cysteine conjugate beta-lyase and thiol glucuronosyl transferase activities.
PubMed:[The clinico-laboratory evaluation of the efficacy of the external treatment of microsporosis using a 5% mebetizol ointment].
PubMed:Leaching of antioxidants and vulcanization accelerators from rubber closures into drug preparations.
PubMed:Contact urticaria caused by rubber. Analysis of seven cases.
PubMed:Chromosome aberration and sister chromatid exchange test results with 42 chemicals.
PubMed:Lack of in vivo DNA binding of mercaptobenzothiazole to selected tissues of the rat.
PubMed:Allergic contact dermatitis from shoes: "angry back" without "angry thigh".
PubMed:[Antifungal activity of 6-acetamido-2-alkylthiobenzothiasoles in vitro].
PubMed:[Absorption, distribution, metabolism and excretion of N-cyclohexyl-2-benzothiazyl sulfenamide (CBS), a vulcanizing accelerator, in rats].
PubMed:[Inhibition of Candida albicans transformation from the yeast form to the mycelial form by 2-alkylthio-6-amino- and 2-alkylthio-6-formamido- benzothiazoles].
PubMed:Disposition of 2-mercaptobenzothiazole and 2-mercaptobenzothiazole disulfide in rats dosed intravenously, orally, and topically and in guinea pigs dosed topically.
PubMed:[Toxicity of 2-mercaptobenzothiazole in mice].
PubMed:Inhibition of yeast-mycelium transformation by 2-alkylthio-6-amino- and 2-alkylthio-6-formamidobenzothiazoles and their in vitro antifungal activity.
PubMed:[A QSAR study of synthetic stimulators of growth of domestic animals on the basis of 6-amino-2-mercaptobenzothiazole].
PubMed:Allergic contact dermatitis from a suction socket prosthesis.
PubMed:Isolation, via activity-directed fractionation, of mercaptobenzothiazole and dibenzothiazyl disulfide as 2 allergens responsible for tennis shoe dermatitis.
PubMed:Liquid chromatographic determination of morphine sulfate and some contaminants in injections and bulk drug material: collaborative study.
PubMed:Studies of the reactivity of morpholine, 2-mercaptobenzothiazole and 2 of their derivatives with selected amino acids.
PubMed:Comparative studies of the sensitization potential of morpholine, 2-mercaptobenzothiazole and 2 of their derivatives in guinea pigs.
PubMed:NTP Toxicology and Carcinogenesis Studies of 2-Mercaptobenzothiazole (CAS No. 149-30-4) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
PubMed:Thioacylating intermediates as metabolites of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2,2-trichlorovinyl)-L-cysteine formed by cysteine conjugate beta-lyase.
PubMed:In vitro metabolism of the methylthio group of 2-methylthiobenzothiazole by rat liver.
PubMed:The metabolic origin of the sulfur atom in the sulfhydryl group of 2-thiobenzothiazole metabolites derived from benzothiazyl sulfenamide in the rat.
PubMed:Allergic contact dermatitis mimicking mycosis fungoides.
PubMed:Contamination of contrast agent by MBT in rubber seals.
PubMed:Alpha-ketoacids stimulate rat renal cysteine conjugate beta-lyase activity and potentiate the cytotoxicity of S-(1,2-dichlorovinyl)-L-cysteine.
PubMed:[Experimental evaluation of fungicidal activity of 5% mebethizole ointment in topical therapy of Microsporum infection].
PubMed:Metabolic activation and detoxication of nephrotoxic cysteine and homocysteine S-conjugates.
PubMed:[Characterization by thin layer chromatography of benzothiazole derivatives and beta-sitosterol leached by disposable syringes].
PubMed:Cysteine conjugate beta-lyase in the gastrointestinal bacterium Eubacterium limosum.
PubMed:[Study of the gentoxocity of pharmaceutic preparations using rapid methods].
PubMed:Dermatitis from mercaptobenzothiazole in a Foley catheter.
PubMed:Determination of bismuth by flame atomic-absorption spectrophotometry after separation by adsorption of its 2-mercaptobenzothiazole complex on microcrystalline naphthalene.
PubMed:Mass spectral identification of benzothiazole derivatives leached into injections by disposable syringes.
PubMed:[The use of short-term tests for oxidation studies of drugs. 2. Kinetics of 2-mercaptobenzthiazole oxidation].
PubMed:Role of socks in shoe dermatitis.
PubMed:Allergy to MBT and its derivatives.
PubMed:Contamination of injectable solutions with 2-mercaptobenzothiazole leached from rubber closures.
PubMed:[Hypersensitivity to mercaptobenzothiazole].
PubMed:Patch testing with mercaptobenzothiazole and mercapto-mixes.
PubMed:Chemical leaching from Terumo syringe seals.
PubMed:Assay of cysteine conjugate beta-lyase activity with S-(2-benzothiazolyl)cysteine as the substrate.
PubMed:[Effect of vulcanizing accelerants on embryolethality in rats].
PubMed:Determination of 2-mercaptobenzothiazole, tolyltriazole and benzotriazole in coolant formulations by liquid chromatography.
PubMed:Leaching of 2-(2-hydroxyethylmercapto) benzothiazole into contents of disposable syringes.
PubMed:False positive reaction to mercaptobenzthiazole from rubber in eyedrop bottle.
PubMed:Dermatitis from shoes and an amputation prosthesis due to mercaptobenzthiazole and paratertiary butyl formaldehyde resin.
PubMed:A comparison of three guinea-pig sensitization procedures for the detection of 19 reported human contact sensitizers.
PubMed:Patch testing with mixes. Note on mercaptobenzothiazole mix.
PubMed:Testing of selected workplace chemicals for teratogenic potential.
PubMed:Dermatitis from 2-mercaptobenzothiazole in photographic films.
PubMed:Antiviral activity of benzothiazole and benzothiazolinethione derivatives in cell cultures.
PubMed:[Qualitative determination of captax in rubber products, coming in contact with food products, by a spectrophotometric method].
PubMed:[2-mercaptobenzothiazole in the topical treatment of senile warts].
PubMed:[Development of the optimal technology for 2-mercaptobenzothiazole tablets].
PubMed:Synergistic influence of Zn(II) in the extraction-atomic-absorption determination of trace cadmium in waters.
PubMed:2-mercaptobenzothiazole, an inhibitor of dopamine beta-hydroxylase.
PubMed:[Antibacterial effect of 2-mercaptobenzothiazole and its derivatives].
PubMed:[The status of health of workers engaged in the production of the rubber accelerators Captax and Altax].
PubMed:The occurrence of nitrate reductase in apple leaves.
PubMed:Inhibition of banana polyphenoloxidase by 2-mercaptobenzothiazole.
PubMed:[2-mercaptobenzothiazole in the clinical experiment].
PubMed:The enzymic oxidation of chlorogenic acid and some reactions of the quinone produced.
Constit. of cranberries
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