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dextro-2-deoxyribose
D-2-deoxyribose

Supplier Sponsors

Name:(3S,4R)-3,4,5-trihydroxypentanal
CAS Number: 533-67-5Picture of molecule3D/inchi
Other(deleted CASRN):14050-34-1
ECHA EINECS - REACH Pre-Reg:208-573-0
FDA UNII: LSW4H01241
Nikkaji Web:J6.332K
Beilstein Number:1721978
MDL:MFCD00135904
XlogP3-AA:-2.30 (est)
Molecular Weight:134.13150000
Formula:C5 H10 O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 91.00 °C. @ 760.00 mm Hg
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Cladribine Impurity E
Carbosynth
For experimental / research use only.
2-Deoxy-D-ribose
Changzhou Longo Chemical
2-Deoxy-D-ribose
ExtraSynthese
For experimental / research use only.
2-Deoxy-D-ribose
Glentham Life Sciences
2-Deoxy-D-ribose
Santa Cruz Biotechnology
For experimental / research use only.
2-Deoxy-D-ribose
Sigma-Aldrich: Sigma
For experimental / research use only.
2-Deoxy-D-ribose ≥99.0% (TLC)
TCI AMERICA
For experimental / research use only.
2-Deoxy-D-ribose >98.0%(HPLC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for dextro-2-deoxyribose usage levels up to:
 not for fragrance use.
 
Recommendation for dextro-2-deoxyribose flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):533-67-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5460005
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(3S,4R)-3,4,5-trihydroxypentanal
Chemidplus:0000533675
RTECS:SB7230000 for cas# 533-67-5
 
References:
 (3S,4R)-3,4,5-trihydroxypentanal
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:533-67-5
Pubchem (cid):5460005
Pubchem (sid):134977041
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
Golm Metabolome Database:Search
KEGG (GenomeNet):C01801
HMDB (The Human Metabolome Database):HMDB03224
FooDB:FDB023126
YMDB (Yeast Metabolome Database):YMDB00661
Export Tariff Code:2940.00.6000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
2-deoxy-D-ribose
2-deoxy-dextro-ribose
D-2-deoxyribose
D-erythro-pentose, 2-deoxy-
 thyminose
(3S,4R)-3,4,5-trihydroxypentanal
 

Articles:

PubMed:Phormidolides B and C, Cytotoxic Agents from the Sea: Enantioselective Synthesis of the Macrocyclic Core.
PubMed:DERA is the human deoxyribose phosphate aldolase and is involved in stress response.
PubMed:Evaluation of antioxidant and antiproliferative activity of Flueggea leucopyrus Willd (katupila).
PubMed:The kinetic analysis of the substrate specificity of motif 5 in a HAD hydrolase-type phosphosugar phosphatase of Arabidopsis thaliana.
PubMed:Carbohydrate radicals: from ethylene glycol to DNA strand breakage.
PubMed:Modeling proton-induced damage on 2-deoxy-D-ribose. Conformational analysis.
PubMed:Antioxidant and DNA damage protective properties of anthocyanin-rich extracts from Hibiscus and Ocimum: a comparative study.
PubMed:Thymidine phosphorylase influences [(18)F]fluorothymidine uptake in cancer cells and patients with non-small cell lung cancer.
PubMed:In situ generation of a hydroxyl radical by nanoporous activated carbon derived from rice husk for environmental applications: kinetic and thermodynamic constants.
PubMed:Conformational studies of gas-phase ribose and 2-deoxyribose by density functional, second order PT and multi-level method calculations: the pyranoses, furanoses, and open-chain structures.
PubMed:Looking at radiation damage on prebiotic building blocks.
PubMed:Conformational preference and chiroptical response of carbohydrates D-ribose and 2-deoxy-D-ribose in aqueous and solid phases.
PubMed:Six pyranoside forms of free 2-deoxy-D-ribose.
PubMed:Ab initio treatment of ion-induced charge transfer dynamics of isolated 2-deoxy-D-ribose.
PubMed:Asymmetric Formal Total Synthesis of the Stemofoline Alkaloids: The Evolution, Development and Application of a Catalytic Dipolar Cycloaddition Cascade.
PubMed:Alpha-lipoic acid treatment reverses 2-deoxy-D-ribose-induced oxidative damage and suppression of insulin expression in pancreatic beta-cells.
PubMed:Molecular basis for the regulation of hypoxia-inducible factor-1α levels by 2-deoxy-D-ribose.
PubMed:Elevated citrate levels in non-alcoholic fatty liver disease: the potential of citrate to promote radical production.
PubMed:Glycation of glutamate cysteine ligase by 2-deoxy-d-ribose and its potential impact on chemoresistance in glioblastoma.
PubMed:Chrysanthemum zawadskii extract protects osteoblastic cells from highly reducing sugar-induced oxidative damage.
PubMed:Pentose oxidation by acetic acid bacteria led to a finding of membrane-bound purine nucleosidase.
PubMed:In vitro antioxidant activities of three red wine polyphenols and their mixtures: an interaction study.
PubMed:HAD hydrolase function unveiled by substrate screening: enzymatic characterization of Arabidopsis thaliana subclass I phosphosugar phosphatase AtSgpp.
PubMed:The flavonoid glabridin attenuates 2-deoxy-D-ribose-induced oxidative damage and cellular dysfunction in MC3T3-E1 osteoblastic cells.
PubMed:Enantioselective formal total syntheses of didehydrostemofoline and isodidehydrostemofoline through a catalytic dipolar cycloaddition cascade.
PubMed:Cerebrolysin administration reduces oxidative stress-induced apoptosis in lymphocytes from healthy individuals.
PubMed:Effects of cerebrolysin administration on oxidative stress-induced apoptosis in lymphocytes from CADASIL patients.
PubMed:[Metabolite changes in the greasy tongue coating of patients with chronic gastritis].
PubMed:Synthetic approaches to a chiral 4-amino-3-hydroxy piperidine with pharmaceutical relevance.
PubMed:Bridging QTAIM with vibrational spectroscopy: the energy of intramolecular hydrogen bonds in DNA-related biomolecules.
PubMed:Inhibition of pyrimidine and purine nucleoside phosphorylases by a 3,5-dichlorobenzoyl-substituted 2-deoxy-D-ribose-1-phosphate derivative.
PubMed:Amino acid-mediated aldolase immobilisation for enhanced catalysis and thermostability.
PubMed:Gliclazide does not fully prevent 2-deoxy-D-ribose-induced oxidative damage because it does not restore glutathione content in a pancreatic β-cell line.
PubMed:Apigenin attenuates 2-deoxy-D-ribose-induced oxidative cell damage in HIT-T15 pancreatic β-cells.
PubMed:Cloning and characterisation of a new 2-deoxy-D-ribose-5-phosphate aldolase from Rhodococcus erythropolis.
PubMed:Platelet-derived endothelial cell growth factor/thymidine phosphorylase inhibitor augments radiotherapeutic efficacy in experimental colorectal cancer.
PubMed:Altered apoptosis regulation in Kufor-Rakeb syndrome patients with mutations in the ATP13A2 gene.
PubMed:Lewis acid catalyzed cyclization of glycals/2-deoxy-D-ribose with arylamines: additional findings on product structure and reaction diastereoselectivity.
PubMed:Phenylboronic acid esters of the common 2-deoxy-aldoses.
PubMed:Oxidative stress-induced apoptosis in two patients with Alagille syndrome.
PubMed:The crystal structure of the CeNA:RNA hybrid ce(GCGTAGCG):r(CGCUACGC).
PubMed:Ribose sugars generate internal glycation cross-links in horse heart myoglobin.
PubMed:Platelet derived endothelial cell growth factor/thymidine phosphorylase enhanced human IgE production.
PubMed:Separation of oligonucleotide phosphorothioate diastereoisomers by pellicular anion-exchange chromatography.
PubMed:Synthesis of the WXYZA' domain of maitotoxin.
PubMed:Stable and efficient immobilization technique of aldolase under consecutive microwave irradiation at low temperature.
PubMed:2-deoxyribose deprives cultured astrocytes of their glutathione.
PubMed:Synthesis of the QRSTU domain of maitotoxin and its 85-epi- and 86-epi-diastereoisomers.
PubMed:A greener enantioselective synthesis of the antiviral agent North-methanocarbathymidine (N-MCT) from 2-deoxy-d-ribose.
PubMed:Microspherules from sugars in the absence of nitrogen.
PubMed:Specificity and mutational analysis of the metal-dependent 3-deoxy-D-manno-octulosonate 8-phosphate synthase from Acidithiobacillus ferrooxidans.
PubMed:A new DNA building block, 4'-selenothymidine: synthesis and modification to 4'-seleno-AZT as a potential anti-HIV agent.
PubMed:Simultaneous detection of pro- and antioxidative effects in the variants of the deoxyribose degradation assay.
PubMed:Protecting-group-free synthesis of 2-deoxy-aza-sugars.
PubMed:Kaempferol protects HIT-T15 pancreatic beta cells from 2-deoxy-D-ribose-induced oxidative damage.
PubMed:2-Deoxy-D-ribose induces cellular damage by increasing oxidative stress and protein glycation in a pancreatic beta-cell line.
PubMed:X-ray structure of 1,3,4-tri-O-acetyl-2-deoxy-beta-d-erythro-pentopyranose.
PubMed:Kaempferol attenuates 2-deoxy-d-ribose-induced oxidative cell damage in MC3T3-E1 osteoblastic cells.
PubMed:2-Deoxy-D-ribose, a downstream mediator of thymidine phosphorylase, regulates tumor angiogenesis and progression.
PubMed:Apoptosis in CADASIL: an in vitro study of lymphocytes and fibroblasts from a cohort of Italian patients.
PubMed:Induction of single strand breaks, and base lesions in plasmid DNA films induced by carbon, nitrogen, and oxygen KLL Auger process.
PubMed:Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of colony-forming units and endothelial progenitor cell cultures.
PubMed:Evaluation of antioxidant activity of some common mosses.
PubMed:Myricetin, a naturally occurring flavonoid, prevents 2-deoxy-D-ribose induced dysfunction and oxidative damage in osteoblastic MC3T3-E1 cells.
PubMed:Precise determination of 2-deoxy-D-ribose internal energies after keV proton collisions.
PubMed:Protective effect of caffeic acid phenethyl ester on tert-butyl hydroperoxide-induced oxidative hepatotoxicity and DNA damage.
PubMed:2-deoxy-d-ribose induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.
PubMed:Total synthesis of (-)-brevenal: a concise synthetic entry to the pentacyclic polyether core.
PubMed:2-Deoxy-D-ribose-induced oxidative stress causes apoptosis in human monocytic cells: prevention by pyridoxal-5'-phosphate.
PubMed:Thymidine phosphorylase inhibits the expression of proapoptotic protein BNIP3.
PubMed:Photofragmentation of 2-deoxy-D-ribose molecules in the gas phase.
PubMed:Double-strand DNA cleavage induced by oxindole-Schiff base copper(II) complexes with potential antitumor activity.
PubMed:Synthesis of (+)-obtusenyne.
PubMed:Oxidative-stress-induced apoptosis in PBLs of two patients with Parkinson disease secondary to alpha-synuclein mutation.
PubMed:Synthesis of an enantiomeric DNA oligomer and its T-HgII-T base-pair formation.
PubMed:Hyperthermal (1-100 eV) nitrogen ion scattering damage to D-ribose and 2-deoxy-D-ribose films.
PubMed:Sequential aldol condensation catalyzed by hyperthermophilic 2-deoxy-d-ribose-5-phosphate aldolase.
PubMed:Hesperetin attenuates the highly reducing sugar-triggered inhibition of osteoblast differentiation.
PubMed:Enantiospecific synthesis of the heparanase inhibitor (+)-trachyspic acid and stereoisomers from a common precursor.
PubMed:Protective effects of kahweol and cafestol against hydrogen peroxide-induced oxidative stress and DNA damage.
PubMed:The antimicrobial peptide PR-39 has a protective effect against HeLa cell apoptosis.
PubMed:[Molecular basis for the inhibition of anticancer agents-induced apoptosis by thymidine phosphorylase].
PubMed:Evaluation of 5'-deoxy-5'-[F-18]fluorothymidine as a tracer of intracellular thymidine phosphorylase activity.
PubMed:Hydroxyl radical scavenging activity of a new ophthalmic viscosurgical device.
PubMed:Oxidative stress response in telomerase-immortalized fibroblasts from a centenarian.
PubMed:In vitro evidence for an antioxidant role of 3-hydroxykynurenine and 3-hydroxyanthranilic acid in the brain.
PubMed:Directed evolution of an industrial biocatalyst: 2-deoxy-D-ribose 5-phosphate aldolase.
PubMed:Ribokinase from E. coli: expression, purification, and substrate specificity.
PubMed:Chemical composition and in vitro antioxidant evaluation of commercial water-soluble willow herb (Epilobium angustifolium L.) extracts.
PubMed:Human fibroblasts undergo oxidative stress-induced apoptosis without internucleosomal DNA fragmentation.
PubMed:2-Deoxy-L-ribose inhibits the invasion of thymidine phosphorylase-overexpressing tumors by suppressing matrix metalloproteinase-9.
PubMed:Quantification of ion-induced molecular fragmentation of isolated 2-deoxy-D-ribose molecules.
PubMed:10-100 eV Ar+ ion induced damage to D-ribose and 2-deoxy-D-ribose molecules in condensed phase.
PubMed:Di-imine copper(II) complexes as redox mediator and modulator in 2-deoxy-D-ribose oxidative damage.
PubMed:Oligonucleotides with cyclohexene-nucleoside building blocks: crystallization and preliminary X-ray studies of a left-handed sequence GTGTACAC.
PubMed:2-Deoxy-D-ribose inhibits hypoxia-induced apoptosis by suppressing the phosphorylation of p38 MAPK.
PubMed:Phenotypic characteristics and tendency to apoptosis of peripheral blood mononuclear cells from HIV+ long term non progressors.
PubMed:Enhanced ROS-generation in lymphocytes from Alzheimer's patients.
PubMed:[Effect of some nonsteroid antiinflammatory drugs on Fenton-reaction initiated degradation of 2-deoxy-D-ribose].
PubMed:Substrate ambiguity and crystal structure of Pyrococcus furiosus 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase: an ancestral 3-deoxyald-2-ulosonate-phosphate synthase?
PubMed:Elevated cAMP level attenuates 2-deoxy-d-ribose-induced oxidative damage in pancreatic beta-cells.
PubMed:Resistance of human astrocytoma cells to apoptosis induced by mitochondria-damaging agents: possible implications for anticancer therapy.
PubMed:Synergistic effects of flavonoids and ascorbate on enhancement in DNA degradation induced by a bleomycin-Fe complex.
PubMed:Cell-death mechanisms in the IPLB-LdFB insect cell line: a nuclear located Bcl-2-like molecule as a possible controller of 2-deoxy-D-ribose-mediated DNA fragmentation.
PubMed:Decomposition of 2-deoxy-D-ribose by irradiation with 0.6 keV electrons and by 0.5 keV ultrasoft X-rays.
PubMed:Cell response to oxidative stress induced apoptosis in patients with Leber's hereditary optic neuropathy.
PubMed:The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression.
PubMed:In vitro exposure of human lymphocytes to 900 MHz CW and GSM modulated radiofrequency: studies of proliferation, apoptosis and mitochondrial membrane potential.
PubMed:1800 MHz radiofrequency (mobile phones, different Global System for Mobile communication modulations) does not affect apoptosis and heat shock protein 70 level in peripheral blood mononuclear cells from young and old donors.
PubMed:Lymphoblastoid cell lines of Rett syndrome patients exposed to oxidative-stress-induced apoptosis.
PubMed:Thermodynamic properties of nucleotide reductase reactions.
PubMed:Facile route for the synthesis of the iminosugar nucleoside (3R,4R)-1-(pyren-1-yl)-4-(hydroxymethyl)pyrrolidin-3-ol.
PubMed:The nucleoside derivative 5'-O-trityl-inosine (KIN59) suppresses thymidine phosphorylase-triggered angiogenesis via a noncompetitive mechanism of action.
PubMed:Polyamine depletion switches the form of 2-deoxy-D-ribose-induced cell death from apoptosis to necrosis in HL-60 cells.
PubMed:Ion desorption from DNA components irradiated with 0.5 keV ultrasoft X-ray photons.
PubMed:Blockage of 2-deoxy-D-ribose-induced angiogenesis with rapamycin counteracts a thymidine phosphorylase-based escape mechanism available for colon cancer under 5-fluorouracil therapy.
PubMed:Inhibition of metastasis of tumor cells overexpressing thymidine phosphorylase by 2-deoxy-L-ribose.
PubMed:Experimental evidence for the existence of the passive antitumor defense system formed by the synergistic action of certain small substances of the circulatory system.
PubMed:Antioxidant properties of aqueous extracts from selected lamiaceae species grown in Turkey.
PubMed:[Thymidine phosphorylase inhibits apoptosis induced by anticancer agents].
PubMed:Analysis of reducing carbohydrates by reductive tryptamine derivatization prior to micellar electrokinetic capillary chromatography.
PubMed:Antioxidant effect of phenelzine on MPP+-induced cell viability loss in differentiated PC12 cells.
PubMed:Thiamine protects against paraquat-induced damage: scavenging activity of reactive oxygen species.
PubMed:Conversion of 2-deoxy-D-ribose into 2-amino-5-(2-deoxy-beta-D-ribofuranosyl)pyridine, 2'-deoxypseudouridine, and other C-(2'-deoxyribonucleosides).
PubMed:Regulation of expression of the 2-deoxy-D-ribose utilization regulon, deoQKPX, from Salmonella enterica serovar typhimurium.
PubMed:Resveratrol modulates apoptosis and oxidation in human blood mononuclear cells.
PubMed:Thymidine phosphorylase induces angiogenesis in vivo and in vitro: an evaluation of possible mechanisms.
PubMed:PDGF and TGF-beta partially prevent 2-deoxy-D-ribose-induced apoptosis in the fat body cell line IPLB-LdFB from the insect Lymantria dispar.
PubMed:Age-dependent changes in the susceptibility to apoptosis of peripheral blood CD4+ and CD8+ T lymphocytes with virgin or memory phenotype.
PubMed:Thymidine phosphorylase inhibits apoptosis induced by cisplatin.
PubMed:Comparison of the antioxidant properties of wound dressing materials--carboxymethylcellulose, hyaluronan benzyl ester and hyaluronan, towards polymorphonuclear leukocyte-derived reactive oxygen species.
PubMed:The first crystal structure of archaeal aldolase. Unique tetrameric structure of 2-deoxy-d-ribose-5-phosphate aldolase from the hyperthermophilic archaea Aeropyrum pernix.
PubMed:Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase.
PubMed:A porphyrin C-nucleoside incorporated into DNA.
PubMed:Ambroxol inhibits peroxynitrite-induced damage of alpha1-antiproteinase and free radical production in activated phagocytic cells.
PubMed:BCL-2 does not control programmed cell death in the IPLB-LdFB cell line from the insect Lymantria dispar.
PubMed:Thymidine phosphorylase suppresses Fas-induced apoptotic signal transduction independent of its enzymatic activity.
PubMed:Detection of 2-deoxy-D-ribose radicals generated by the reaction with the hydroxyl radical using a rapid flow-ESR method.
PubMed:L-tryptophan as an antioxidant in human placenta extract.
PubMed:Suppression of thymidine phosphorylase-mediated angiogenesis and tumor growth by 2-deoxy-L-ribose.
PubMed:Comparison of the antioxidant properties of HYAFF-11p75, AQUACEL and hyaluronan towards reactive oxygen species in vitro.
PubMed:One-pot two-step enzymatic coupling of pyrimidine bases to 2-deoxy-D-ribose-5-phosphate. A new strategy in the synthesis of stable isotope labeled deoxynucleosides.
PubMed:Molecular basis for the inhibition of hypoxia-induced apoptosis by 2-deoxy-D-ribose.
PubMed:Antiradical activity of water soluble components in common diet vegetables.
PubMed:Pathways for alpha-D-ribose utilization for nucleobase salvage and 5-fluorouracil activation in rat brain.
PubMed:Aqueous infusions of Mediterranean herbs exhibit antioxidant activity towards iron promoted oxidation of phospholipids, linoleic acid, and deoxyribose.
PubMed:Altered thymidine metabolism due to defects of thymidine phosphorylase.
PubMed:Protective effect of serotonin on 6-hydroxydopamine- and dopamine-induced oxidative damage of brain mitochondria and synaptosomes and PC12 cells.
PubMed:Age-related increase of oxidative stress-induced apoptosis in mice prevention by Ginkgo biloba extract (EGb761).
PubMed:Applications of 5-Endo-trigonal Cyclization: Construction of Compounds Relevant to the Synthesis of Prostaglandins and Methyl epi-Jasmonate.
PubMed:Synthesis of the Chiral CD Rings of Paclitaxel from 2-Deoxy-D-ribose: Novel 1,2-Addition of a Dienolate to a Chiral Ketone.
PubMed:Observation of covalent intermediates in an enzyme mechanism at atomic resolution.
PubMed:X-ray absorption near-edge structure (XANES) spectral changes of 2-deoxy-D-ribose by irradiation within the energy region around the oxygen K-shell absorption edge.
PubMed:Thiyl radicals abstract hydrogen atoms from carbohydrates: reactivity and selectivity.
PubMed:An anti-Bcl-2 antibody prevents 2-deoxy-D-ribose-induced apoptosis in the IPLB-LdFB insect cell line.
PubMed:Involvement of PI 3-kinase, PKA and PKC in PDGF- and TGF-beta-mediated prevention of 2-deoxy-D-ribose-induced apoptosis in the insect cell line, IPLB-LdFB.
PubMed:X-ray absorption near edge structures of DNA or its components around the oxygen K-shell edge.
PubMed:Decreased susceptibility to oxidative stress-induced apoptosis of peripheral blood mononuclear cells from healthy elderly and centenarians.
PubMed:New Melanoidin-like Maillard Polymers from 2-Deoxypentoses.
PubMed:Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors.
PubMed:C60 carboxyfullerene exerts a protective activity against oxidative stress-induced apoptosis in human peripheral blood mononuclear cells.
PubMed:Age-related changes of apoptotic cell death in human lymphocytes.
PubMed:Probing the stereochemistry of E. coli 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (phenylalanine-sensitive)-catalyzed synthesis of KDO 8-P analogues.
PubMed:Enhanced 2-deoxy-D-ribose-induced-apoptosis, a phenotype of lymphocytes from old donors, is not observed in the Werner syndrome.
PubMed:Protective effect of harmalol and harmaline on MPTP neurotoxicity in the mouse and dopamine-induced damage of brain mitochondria and PC12 cells.
PubMed:Apoptotic response and cell cycle transition in ataxia telangiectasia cells exposed to oxidative stress.
PubMed:Formation of malonaldehyde and acetaldehyde from the oxidation of 2'-deoxyribonucleosides.
PubMed:DNA damage by copper(II) complexes: coordination-structural dependence of reactivities.
PubMed:2-deoxy-d-ribose-induced apoptosis in HL-60 cells is associated with the cell cycle progression by spermidine.
PubMed:An improved route to 1,2-dideoxy-beta-1-phenyl-D-ribofuranose.
PubMed:Prevention of hypoxia-induced apoptosis by the angiogenic factor thymidine phosphorylase.
PubMed:Prevention of Oxidation and Apoptosis in Human Peripheral Blood Mononuclear Cells Exposed to Calcium Dobesilate.
PubMed:Inhibitors of glycogen phosphorylase b: synthesis, biochemical screening, and molecular modeling studies of novel analogues of hydantocidin.
PubMed:Thymidine phosphorylase, 2-deoxy-D-ribose and angiogenesis.
PubMed:Effects of platelet-derived endothelial cell growth factor/thymidine phosphorylase, substrate, and products in a three-dimensional model of angiogenesis.
PubMed:Polyamine depletion protects HL-60 cells from 2-deoxy-D-ribose-induced apoptosis.
PubMed:The highly reducing sugar 2-deoxy-D-ribose induces apoptosis in human fibroblasts by reduced glutathione depletion and cytoskeletal disruption.
PubMed:Inhibitory potency of R-region specific antisense oligonucleotides against in vitro DNA polymerization and template-switching reactions catalysed by HIV-1 reverse transcriptase.
PubMed:D-2-deoxyribose and D-arabinose, but not D-ribose, stabilize the cytosine tetrad (i-DNA) structure.
PubMed:Resistance to apoptosis in Fanconi's anaemia. An ex vivo study in peripheral blood mononuclear cells.
PubMed:Quantitation of hydroxyl radicals produced by radiation and copper-linked oxidation of ascorbate by 2-deoxy-D-ribose method.
PubMed:Increased apoptotic response to 2-deoxy-D-ribose in ataxia-telangiectasia.
PubMed:Influence of titanium oxide and titanium peroxy gel on the breakdown of hyaluronan by reactive oxygen species.
PubMed:Efficient and beta-Stereoselective Synthesis of 4(5)-(beta-D-Ribofuranosyl)- and 4(5)-(2-Deoxyribofuranosyl)imidazoles(1).
PubMed:meso-DNAs with homopurine sequences: analysis of their interaction with natural DNAs.
PubMed:Biotyping of Escherichia coli in microwell plates.
PubMed:A novel action for adenosine: apoptosis of astroglial cells in rat brain primary cultures.
PubMed:Inhibition of the growth of a murine and various human tumor cell lines in culture and in mice by mixture of certain substances of the circulatory system.
PubMed:Preparation and heteronuclear 2D NMR spectroscopy of a DNA dodecamer containing a thymidine residue with a uniformly 13C-labeled deoxyribose ring.
PubMed:D-ribose and deoxy-D-ribose induce apoptosis in human quiescent peripheral blood mononuclear cells.
PubMed:A miniaturized biotyping system for strain discrimination in Escherichia coli.
PubMed:Nucleic acids induce the formation of a carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in a model system.
PubMed:Synthesis of 3'-alkylthio-2',3'-dideoxy nucleosides with potential anti-HIV activity from 2-deoxy-D-ribose, using a phosphorus pentoxide reagent.
PubMed:Synthesis and antiviral activity of acyclic nucleosides with a 3(S),5-dihydroxypentyl or 4(R)-methoxy-3(S),5-dihydroxypentyl side chain.
PubMed:Structural and stereospecific requirements for the nucleoside-triggered germination of Bacillus cereus spores.
PubMed:Molecular mechanisms of radiation induced DNA damage: H-abstraction and beta-cleavage.
PubMed:Pyrolysis radicals formed by ultrasound in aqueous solutions of nucleotides: a spin trapping study.
PubMed:Sonolysis of concentrated aqueous solutions of nonvolatile solutes: spin-trapping evidence for free radicals formed by pyrolysis.
PubMed:Molecular mechanisms for the hypoxia-dependent activation of 3-amino-1,2,4-benzotriazine-1,4-dioxide (SR 4233).
PubMed:Inhibition by 2-deoxy-D-ribose of DNA synthesis and growth in Raji cells.
PubMed:Effects of carbohydrates on insulin release from the isolated islets.
PubMed:Carbohydrate radicals: from ethylene glycol to DNA strand breakage.
PubMed:Automation of a fluorometric method for the determination of 2-deoxy-D-glucose.
PubMed:Induction of deoxyribose-5-phosphate aldolase of Bacillus cereus by deoxyribonucleosides.
PubMed:Specificity and sodium dependence of the active nucleoside transport system in choroid plexus.
PubMed:Quantitation of xylose from plasma and urine by capillary column gas chromatography.
PubMed:Inhibition by specific monosaccharides of interleukin 2-induced thymocyte proliferation.
PubMed:[Comparison of the neutron- and gamma-radiation-induced transformations of 2-deoxy-D-ribose in aqueous solutions].
PubMed:On the significance of the cytochrome P-450-dependent hydroxyl radical-mediated oxygenation mechanism.
PubMed:13C NMR relaxation and conformational flexibility of the deoxyribose ring.
PubMed:Oxygen uptake in the radiolysis of aqueous solutions of nucleic acids and their constituents.
PubMed:Mutagenicity of gamma-irradiated oxygenated and deoxygenated solutions of 2-deoxy-D-ribose and D-ribose in Salmonella typhimurium.
PubMed:Mutagenicity of irradiated solutions of nucleic acid bases and nucleosides in Salmonella typhimurium.
PubMed:Induction of sister-chromatid exchanges and chromosome aberrations by gamma-irradiated nucleic acid constituents in CHO cells.
PubMed:Mutagenicity of irradiated solutions of 2-deoxy-D-ribose.
PubMed:[Radiation damage to 2-deoxy-D-ribose in aqueous solutions. The effect of the irradiation conditions on the formation of carbon-carbon bond breakages].
PubMed:The permeability of rat liver lysosomes to sugars. Evidence for carrier-mediated facilitated diffusion.
PubMed:Synthesis of episilon-rhodomycinone glycosides.
PubMed:An apparent lack of stereospecificity in the reaction catalysed by deoxyribose 5-phosphate aldolase due to methyl-group rotation and enolization before product release.
PubMed:The membrane transport of ascorbic acid.
PubMed:Radiation chemistry of DNA model compounds. III. Gamma-radiolysis of 2-deoxy-D-ribose in the crystalline state. Conversion of 2-deoxy-D-ribose into 2,5-dideoxy-D-erythro-pentonic acid via a chain reaction.
PubMed:The mutarotation of 2-deoxy- -D-erythro-pentose ("2-deoxy- -D-ribose"). Conformations, kinetics, and equilibria.
PubMed:Carbohydrate metabolism in Cheddar cheese. I. N-acetylneuraminic acid, 2-deoxy-D-ribose, and phosphorylated sugars.
PubMed:Formation of 2-amino-2-deoxy-D-ribose 5-phosphate and 2-amino-2-deoxy-D-lyxose 5-phosphate by extracts of Streptomyces alboniger.
PubMed:Free radicals in gamma-irradiated 2-deoxy-D-ribose: electron spin resonance of single crystals and polycrystalline material.
PubMed:[Electron spin resonance on gamma-irradiated monocrystals of 2-deoxy-D-ribose].
PubMed:Spectrophotometric analysis of ribose and 2-deoxy-D-ribose alone and in mixtures.
PubMed:5-methyl-3(2H)-furanone from acid-catalyzed solvolysis of 2-deoxy-D-ribose.
PubMed:Anomeric purine nucleosides of the furanose form of 2-amino-2-deoxy-D-ribose.
PubMed:D-arabinose and 2-deoxy-D-ribose derivatives.
PubMed:2-Amino-2-deoxy-D-xylose and 2-amino-2-deoxy-D-ribose and their 1-thioglycofuranosides.
PubMed:SPECTROPHOTOMETRIC ANALYSES OF 2-DEOXY-D-RIBOSE IN PRESENCE OF NUCLEOSIDES.
PubMed:Degradation of deoxyribose by E. coli; studies with cell-free extract and isolation of 2-deoxy-D-ribose 5-phosphate.
PubMed:Adaptation of E. coli to 2-deoxy D-ribose.
PubMed:2-Deoxy-D-ribose. I. A simplified preparation of 2-deoxy-D-ribose based on treatment of alpha-D-glucose monohydrate with solid calcium hydroxide.
PubMed:Pentose fermentation by Lactobacillus plantarum. V. Fermentation of 2-deoxy-D-ribose.
PubMed:A new synthesis of 2-deoxy-D-ribose.
PubMed:Conversion of D-arabinose into 2-deoxy-D-ribose and 3-deoxy D-xylose.
 
Notes:
Deoxyribose is an aldopentose, a monosaccharide containing five carbon atoms, and including an aldehyde functional group. It is derived from the pentose sugar ribose by the replacement of the hydroxyl group at the 2 position with hydrogen, leading to the net loss of an oxygen atom, and has chemical formula C5H10O4. In deoxyribose, the carbon furthest from the attached carbon is stripped of the oxygen atom in what would be a hydroxyl group in ribose. The common base adenine (a purine derivative) coupled to deoxyribose is called deoxyadenosine. The 5-triphosphate derivative of adenosine, commonly called adenosine triphosphate (ATP) is an important energy transport molecule in cells. -- Wikipedia [HMDB]
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