EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

thiabendazole
2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole

Sponsors

Name:4-(1H-benzimidazol-2-yl)-1,3-thiazole
CAS Number: 148-79-8Picture of molecule3D/inchi
Other:1135441-27-8
ECHA EINECS - REACH Pre-Reg:205-725-8
FDA UNII:N1Q45E87DT
Nikkaji Web:J2.961K
Beilstein Number:0611403
MDL:MFCD00005587
XlogP3:2.50 (est)
Molecular Weight:201.25179000
Formula:C10 H7 N3 S
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:antimicrobial agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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NCBI:Search
 
Physical Properties:
Appearance:white or cream powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 300.00 °C. @ 760.00 mm Hg
Boiling Point: 446.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:4.000000 mm/Hg @ 25.00 °C. (est)
Flash Point: 439.00 °F. TCC ( 226.20 °C. ) (est)
logP (o/w): 2.470
Soluble in:
 water, 50 mg/L @ 25 °C (exp)
 water, 335.2 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antimicrobial agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
Thiabendazole >98%
Odor: characteristic
Use: Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.
Santa Cruz Biotechnology
For experimental / research use only.
Thiabendazole ≥98%
Sarchem Laboratories
For experimental / research use only.
Thiabendazole
Sigma-Aldrich: Sigma
For experimental / research use only.
Thiabendazole ≥99%, powder
TCI AMERICA
For experimental / research use only.
2-(4-Thiazolyl)benzimidazole >98.0%(GC)(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-chicken LD50 4000 mg/kg
Veterinarno-Meditsinski Nauki. Veterinary Science. Vol. 19(3), Pg. 99, 1982.

oral-man TDLo 47619 ug/kg/1D
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Pediatrics. Vol. 102, Pg. 317, 1983.

oral-mouse LD50 1300 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 55(10), Pg. 28, 1990.

oral-rabbit LD50 3850 mg/kg
"Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976Vol. -, Pg. -, 1971/1976.

oral-rat LD50 2080 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ATAXIA
Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. Vol. 36(1-4), Pg. 10, 1989.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: antimicrobial agents
Recommendation for thiabendazole usage levels up to:
 not for fragrance use.
 
Recommendation for thiabendazole flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Reasoned opinion on the review of the existing maximum residue levels (MRLs) for thiabendazole according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf

Conclusion on the peer review of the pesticide risk assessment of the active substance thiabendazole
View page or View pdf

Revision of the review of the existing maximum residue levels for thiabendazole
View page or View pdf

EPI System: View
Daily Med:search
NLM Hazardous Substances Data Bank:Search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
Env. Mutagen Info. Center:Search
EPA Substance Registry Services (TSCA):148-79-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5430
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
4-(1H-benzimidazol-2-yl)-1,3-thiazole
Chemidplus:0000148798
EPA/NOAA CAMEO:hazardous materials
RTECS:DE0700000 for cas# 148-79-8
 
References:
 4-(1H-benzimidazol-2-yl)-1,3-thiazole
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5430
Pubchem (sid):134975426
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C07131
HMDB (The Human Metabolome Database):HMDB14868
FooDB:FDB000906
Export Tariff Code:2934.10.2000
Haz-Map:View
Household Products:Search
MedlinePlusSupp:View
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
Formulations/Preparations:
•usepaopp pesticide code 060101; trade names: arbotect; mertect; tbz; apl-luster; bioguard; bovizole; eprofil; equizole; lombristop; mertect 160; metasol tk 100; mintesol; mycozol; mk 360; nemapan; omnizole; polival; tebuzate; tecto; thibenzole 200; thiprazole; top form wormer; agrosol, component of (with 081301); agrosol t, component of (with 079801). •the following thiabendazole formulation types are registered: a ready-to-use, dusts, flowable concentrates, emulsifiable concentrates, wettable powders, granules, and water dispersable granules. •oral: suspension: 500 mg5 ml mintezol (merck); tablets, chewable: 500 mg mintezol (scored) (merck). •40, 60 and 90% wettable powders; 45% wtvol flowable suspension; thermal fumigation tablet containing 7 g thiabendazole; 5 and 10% dusts and others. •formulations include wettable powders (400,000, and 900 g active ingredientkg), flowable suspensions (450 g active ingredientl), and fumigation tablets (7 g active ingredient). •combinations: captan t (captan + thiabendazole), rtu flowable fungicide (thiram + thiabendazole), rival (captan + pcnb + thiabendazole) •mertect (r) 340-f fungicide; active ingredient 42.30% thiabendazole •arbotect 20-s fungicide; active ingredient 26.60% thiabendazole •thiabendazole technical mf; active ingredient 99.50% thiabendazole •tecto mp 340; active ingredient 42.30% thiabendazole •tecto-shield mp 100; active ingredient 99.50% thiabendazole •azotech; active ingredients 19.50% thiabendazole and 15.00% azoxystrobin •sporgard; active ingredients 19.04% thiabendazole, 1.92% fludioxonil, and 19.04% azoxystrobin •gustafson lsp flowable fungicide; active ingredient 30.00% thiabendazole •decco salt no. 19; active ingredient 99.50% thiabendazole •freshgard 598; active ingredient 99.50% thiabendazole •ultra-fresh pf-1 fungicide; active ingredient 25.00% thiabendazole •ultra-fresh dw-30; active ingredients 15.00% thiabendazole and 15.00% zinc 2-pyridinethiol-1-oxide •metasol tk-100 dispersion w; active ingredient 50.00% thiabendazole •metasol tk-100; active ingredient 99.50% thiabendazole •thiabendazole dispersion w; active ingredient 50.00% thiabendazole •metasol tk-25 ad; active ingredient 25.00% thiabendazole •metasol tk-50 ad; active ingredient 50.00% thiabendazole •metasol tk-100 technical; active ingredient 99.50% thiabendazole •preventol a17-d; active ingredients 25.50% thiabendazole and 4.2% octhilinone •irgaguard f3000; active ingredient 99.50% thiabendazole •chem-tek 100; active ingredient 99.50% thiabendazole •stay-clean ie; active ingredient 50.00% thiabendazole •super mildex; active ingredient 50.00% thiabendazole •shield-brite tbz; active ingredient 99.50% thiabendazole •krud kutter mc-2; active ingredient 50.00% thiabendazole
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 antimicrobial agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 arbotect
4-benzimidazol-2-yl-1,3-thiazole
4-(1H-benzimidazol-2-yl)-1,3-thiazole
 benzimidazole, 2-(4-thiazolyl)-
1H-benzimidazole, 2-(4-thiazolyl)-
4-(2-benzimidazolyl)thiazole
 bioguard
 bovizole
 drawipas
 equivet TZ
 lombristop
 mertect 160
 mertect 340f
 nemacin
 omnizole
 tecto B
 thiabendazol
 thiabendole
 thiabenzazole
2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole
2-(1,3-thiazol-4-yl)-1H-benzimidazol
2-(1,3-thiazol-4-yl)benzimidazole
2-(4-thiazoly)benzimidazole
2-(4-thiazolyl) benzimidazole
2-(4-thiazolyl)-1H-benzimidazole
2-(4-thiazolyl)benzimidazole
2-(4'-thiazolyl)benzimidazole
 thiprazole
 tibimix 20
 tubazole
 

Articles:

PubMed:High-throughput screening of pesticide and veterinary drug residues in baby food by liquid chromatography coupled to quadrupole Orbitrap mass spectrometry.
PubMed:Thiabendazole uptake in shimeji, king oyster, and oyster mushrooms and its persistence in sterile and nonsterile substrates.
PubMed:Fate of thiabendazole through the treatment of a simulated agro-food industrial effluent by combined MBR/Fenton processes at μg/L scale.
PubMed:Simultaneous determination of azoles antifungal drugs in chicken tissues by ultra-performance liquid chromatography tandem mass spectrometry.
PubMed:Recovery and quantitative detection of thiabendazole on apples using a surface swab capture method followed by surface-enhanced Raman spectroscopy.
PubMed:Detection of thiabendazole applied on citrus fruits and bananas using surface enhanced Raman scattering.
PubMed:Processing factor for a selected group of pesticides in a wine-making process: distribution of pesticides during grape processing.
PubMed:Comparisons of metabolic and physiological changes in rats following short term oral dosing with pesticides commonly found in food.
PubMed:Combined effects of potassium sorbate, hot water and thiabendazole against green mould of citrus fruit and residue levels.
PubMed:Analysis of veterinary drug residues in cheese by ultra-high-performance LC coupled to triple quadrupole MS/MS.
PubMed:Molecular characterization, fitness and mycotoxin production of benzimidazole-resistant isolates of Penicillium expansum.
PubMed:Capillary electrophoresis coupled to mass spectrometry for the determination of anthelmintic benzimidazoles in eggs using a QuEChERS with preconcentration as sample treatment.
PubMed:Residue levels and efficacy of fludioxonil and thiabendazole in controlling postharvest green mold decay in citrus fruit when applied in combination with sodium bicarbonate.
PubMed:[Improved methodology for quantitative determination of thiabendazole].
PubMed:Simple multiresidue extraction method for the determination of fungicides and plant growth regulator in bean sprouts using low temperature partitioning and tandem mass spectrometry.
PubMed:Indirect competitive immunoassay for the detection of fungicide Thiabendazole in whole orange samples by Surface Plasmon Resonance.
PubMed:Determination of fungicide residues in baby food by liquid chromatography-ion trap tandem mass spectrometry.
PubMed:Protocol for an electrospray ionization tandem mass spectral product ion library: development and application for identification of 240 pesticides in foods.
PubMed:Development of an Evidence biochip array kit for the multiplex screening of more than 20 anthelmintic drugs.
PubMed:In vitro anthelmintic activity of the essential oils of Zanthoxylum zanthoxyloides and Newbouldia laevis against Strongyloides ratti.
PubMed:Mutations of β-tubulin codon 198 or 200 indicate thiabendazole resistance among isolates of Penicillium digitatum collected from citrus in Taiwan.
PubMed:Determination of sixteen pesticides in peppers using high-performance liquid chromatography/mass spectrometry.
PubMed:[Study on analytical method for thiabendazole in toasted and seasoned laver by LC-MS/MS].
PubMed:In vitro aneugenic effects of the fungicide thiabendazole evaluated in human lymphocytes by the micronucleus assay.
PubMed:A matrix solid-phase dispersion method for the extraction of seven pesticides from mango and papaya.
PubMed:Electrospray ionization matrix effect as an uncertainty source in HPLC/ESI-MS pesticide residue analysis.
PubMed:Strip-based immunoassay for rapid detection of thiabendazole.
PubMed:Development, validation and application of a methodology based on solid-phase micro extraction followed by gas chromatography coupled to mass spectrometry (SPME/GC-MS) for the determination of pesticide residues in mangoes.
PubMed:Profiling of compounds and degradation products from the postharvest treatment of pears and apples by ultra-high pressure liquid chromatography quadrupole-time-of-flight mass spectrometry.
PubMed:Simultaneous analysis of thiabendazole, carbendazim and 2-aminobenzimidazole in concentrated fruit juices by liquid chromatography after a single mix-mode solid-phase extraction cleanup.
PubMed:Hollow fiber-liquid-phase microextraction of fungicides from orange juices.
PubMed:Comparison of several extraction techniques for multiclass analysis of veterinary drugs in eggs using ultra-high pressure liquid chromatography-tandem mass spectrometry.
PubMed:[Transfer of pesticide residues to crops via cardboard boxes].
PubMed:Fate of vinclozolin, thiabendazole and dimethomorph during storage, handling and forcing of chicory.
PubMed:Determination of pesticide residues in fruit-based soft drinks.
PubMed:[Determination of benomyl, carbendazim and thiabendazole in apple juice concentrate using solid-phase extraction coupled with ion exchange chromatography].
PubMed:Desorption electrospray ionization mass spectrometry for trace analysis of agrochemicals in food.
PubMed:Factors affecting the synergy of thiabendazole, sodium bicarbonate, and heat to control postharvest green mold of citrus fruit.
PubMed:Effect of butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole on cytochrome P450 forms in cultured human hepatocytes.
PubMed:Evaluation of some parameters affecting troublesome pesticide analysis in gas chromatography-ion-trap mass spectrometry.
PubMed:Transcriptome analysis provides new insights into liver changes induced in the rat upon dietary administration of the food additives butylated hydroxytoluene, curcumin, propyl gallate and thiabendazole.
PubMed:A sensitive determination method for carbendazim and thiabendazole in apples by solid-phase microextraction-high performance liquid chromatography with fluorescence detection.
PubMed:Molecularly imprinted capillary electrochromatography for selective determination of thiabendazole in citrus samples.
PubMed:Determination of postharvest fungicides in fruit juices by solid-phase extraction followed by liquid chromatography electrospray time-of-flight mass spectrometry.
PubMed:Analyses of pesticide residues in fruit-based baby food by liquid chromatography/electrospray ionization time-of-flight mass spectrometry.
PubMed:Problems of positive list system revealed by survey of pesticide residue in food.
PubMed:Determination of pesticide residues in foods by acetonitrile extraction and partitioning with magnesium sulfate: collaborative study.
PubMed:Comprehensive multi-residue method for the target analysis of pesticides in crops using liquid chromatography-tandem mass spectrometry.
PubMed:Feasibility of LC/TOFMS and elemental database searching as a spectral library for pesticides in food.
PubMed:Antifungal characteristics of N,N'-hexamethylenebis (4-carbamoyl-1-decylpyridinium bromide).
PubMed:Development of a biological control method against postharvest diseases of citrus fruits.
PubMed:Determination of pesticides in soy-based infant formula using liquid chromatography with electrospray ionization tandem mass spectrometry.
PubMed:[Determination of carbendazim and thiabendazole in tomatoes by solid-phase microextraction coupled with high performance liquid chromatography and fluorescence detection].
PubMed:Genotoxic and aneugenic properties of an imidazole derivative.
PubMed:HPLC imprinted-stationary phase prepared by precipitation polymerisation for the determination of thiabendazole in fruit.
PubMed:Study on the supramolecular interaction of thiabendazole and beta-cyclodextrin by spectrophotometry and its analytical application.
PubMed:Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals.
PubMed:Pesticide residues survey in citrus fruits.
PubMed:Highly sensitive and selective room-temperature phosphorescence determination of thiabendazole by the supramolecular interaction of thiabendazole/beta-cyclodextrin/triton X-100.
PubMed:Evaluation of two fast and easy methods for pesticide residue analysis in fatty food matrixes.
PubMed:Determination of pesticides in apple-based infant foods using liquid chromatography electrospray ionization tandem mass spectrometry.
PubMed:Control of blue mold (Penicillium expansum) by fludioxonil in apples (cv Empire) under controlled atmosphere and cold storage conditions.
PubMed:Application of micellar electrokinetic capillary chromatography to the analysis of uncharged pesticides of environmental impact.
PubMed:Effect of thiabendazole on some rat hepatic xenobiotic metabolising enzymes.
PubMed:Development of a single fluorescence-based optosensor for rapid simultaneous determination of fungicides benomyl and thiabendazole in waters and commercial formulations.
PubMed:Benzimidazole drugs and modulation of biotransformation enzymes.
PubMed:Comparison of the activity of antifungal hexapeptides and the fungicides thiabendazole and imazalil against postharvest fungal pathogens.
PubMed:Release of protein-bound residues of thiabendazole from liver.
PubMed:Fast and easy multiresidue method employing acetonitrile extraction/partitioning and "dispersive solid-phase extraction" for the determination of pesticide residues in produce.
PubMed:Non-conventional methods for the control of post-harvest pear diseases.
PubMed:Simple and rapid determination of thiabendazole, imazalil, and o-phenylphenol in citrus fruit using flow-injection electrospray ionization tandem mass spectrometry.
PubMed:Pesticide residues in biological waste.
PubMed:The comet assay with 8 mouse organs: results with 39 currently used food additives.
PubMed:Estimation of concentrations of antifungal agents allowed as food additives in foods and their daily intake based on official inspection results in Japan in fiscal year 1998.
PubMed:Residue uptake and storage responses of Tarocco blood oranges after preharvest thiabendazole spray and postharvest heat treatment.
PubMed:Thiabendazole uptake and storage performance of cactus pear [Opuntia ficus-indica (L.) Mill. Cv Gialla] fruit following postharvest treatments with reduced doses of fungicide at 52 degrees C.
PubMed:Complexation of several benzimidazole-type fungicides with alpha- and beta-cyclodextrins.
PubMed:Determination of levamisole in animal tissues using liquid chromatography with ultraviolet detection.
PubMed:Optimization and evaluation of low-pressure gas chromatography-mass spectrometry for the fast analysis of multiple pesticide residues in a food commodity.
PubMed:Pesticide residues in oranges from Valencia (Spain).
PubMed:Fungitoxic activity of 12 essential oils against four postharvest citrus pathogens: chemical analysis of thymus capitatus oil and its effect in subatmospheric pressure conditions.
PubMed:Reproductive and neurobehavioural effects of thiabendazole administered to mice in the diet.
PubMed:Developmental toxicity of orally administered thiabendazole in ICR mice.
PubMed:[Anisakiasis of the stomach--a case report from Germany].
PubMed:Comparative Metabolism of Thiabendazole in Cultured Hepatocytes from Rats, Rabbits, Calves, Pigs, and Sheep, Including the Formation of Protein-Bound Residues.
PubMed:Determination of imidacloprid and benzimidazole residues in fruits and vegetables by liquid chromatography-mass spectrometry after ethyl acetate multiresidue extraction.
PubMed:Relationship of (known) control values to (unknown) test values in proficiency studies of pesticide residues.
PubMed:A comparative assessment of potential conditioned taste aversion agents for vertebrate management.
PubMed:An analysis of the possibility for health implications of joint actions and interactions between food additives.
PubMed:Factors affecting imazalil and thiabendazole uptake and persistence in citrus fruits following dip treatments.
PubMed:Determination of benomyl, diphenyl, o-phenylphenol, thiabendazole, chlorpyrifos, methidathion, and methyl parathion in oranges by solid-phase extraction, liquid chromatography, and gas chromatography.
PubMed:Kuwait's total diet study: dietary intake of organochlorine, carbamate, benzimidazole and phenylurea pesticide residues.
PubMed:Bioassays for the detection of growth-promoting agents, veterinary drugs and environmental contaminants in food.
PubMed:Effects of thiabendazole (TBZ) on mitochondrial function in renal cortex of ICR mice.
PubMed:Automated method for cleanup and determination of benomyl and thiabendazole in table-ready foods.
PubMed:Application of ion-exchange cartridge clean-up in food analysis. I. Simultaneous determination of thiabendazole and imazalil in citrus fruit and banana using high-performance liquid chromatography with ultraviolet detection.
PubMed:Cytotoxicity of food preservatives in cultured rat hepatocytes loaded with linolenic acid.
PubMed:Oxidative liver DNA damage in rats treated with pesticide mixtures.
PubMed:Complementation of direct-injection high-performance liquid chromatography and enzyme-linked immunosorbent assay for the analysis of thiabendazole in fruit juices and concentrates.
PubMed:Nephrotoxicity of thioformamide, a proximate toxicant of nephrotoxic thiazoles, in mice depleted of glutathione.
PubMed:Subchronic toxicity of thiabendazole (TBZ) in ICR mice.
PubMed:Major involvement of rabbit liver cytochrome P4501A in thiabendazole 5-hydroxylation.
PubMed:The role of toxicology in the evaluation of new agrochemicals.
PubMed:The carry-through of residues of thiabendazole, tecnazene and chlorpropham from potatoes following manufacture into potato crisps and jacket potato crisps.
PubMed:Determination of thiabendazole residues in white and sweet potatoes by liquid chromatography with fluorescence detection.
PubMed:Induction of chromosome loss in Saccharomyces cerevisiae strain D61.M by selected benzimidazole compounds.
PubMed:U.S. Food and Drug Administration pesticide program: incidence/level monitoring of domestic and imported pears and tomatoes.
PubMed:Determination of thiabendazole in potatoes, fruits, and their processed products by liquid chromatography.
PubMed:Laboratory evaluation of chemical control of aflatoxin production in unshelled peanuts (Arachis hypogaea L.).
PubMed:Mycological evaluation of chemically-treated unshelled peanuts.
PubMed:Capillary gas chromatographic determination of thiabendazole in citrus and apple juices.
PubMed:Determination of thiabendazole in fruits and vegetables by competitive-inhibition enzyme immunoassay.
PubMed:Formation of toxic metabolites from thiabendazole and other thiazoles in mice. Identification of thioamides as ring cleavage products.
PubMed:Cytogenetic effects on human lymphocytes of a mixture of fifteen pesticides commonly used in Italy.
PubMed:Dietary two-generation reproduction study of thiabendazole in Sprague-Dawley rats.
PubMed:The effect of home processing on postharvest fungicide residues in citrus fruit: residues of imazalil, 2-phenylphenol and thiabendazole in 'home-made' marmalade, prepared from late Valencia oranges.
PubMed:Genetic toxicity of a mixture of fifteen pesticides commonly found in the Italian diet.
PubMed:Possible role of thioformamide as a proximate toxicant in the nephrotoxicity of thiabendazole and related thiazoles in glutathione-depleted mice: structure-toxicity and metabolic studies.
PubMed:Developmental toxicity of orally administered thiabendazole in Sprague-Dawley rats and New Zealand white rabbits.
PubMed:Secondary urticaria due to toxocariasis: possibly caused by ingesting raw cattle meat?
PubMed:Prenatal risks deriving from environmental chemicals.
PubMed:Acute renal toxicity of thiabendazole (TBZ) in ICR mice.
PubMed:Comparison of HPTLC and HPLC procedures for the determination of certain xenobiotic residues in apples and pears.
PubMed:Sex difference in the nephrotoxicity of thiabendazole in mice depleted of glutathione by treatment with DL-buthionine sulphoximine.
PubMed:Antiparasitic agents.
PubMed:Nephrotoxicity of thiazoles structurally related to thiabendazole in mice depleted of glutathione by treatment with buthionine sulfoximine.
PubMed:Chronic oral toxicity and carcinogenicity study of thiabendazole in rats.
PubMed:The effects of microwave-baking and oven-baking on thiabendazole residues in potatoes.
PubMed:Comparison of an HPTLC and an HPLC procedure for the determination of chlorpropham, propham and thiabendazole residues in potatoes.
PubMed:New metabolites of thiabendazole and the metabolism of thiabendazole by mouse embryo in vivo and in vitro.
PubMed:Matrix solid phase dispersion isolation and liquid chromatographic determination of five benzimidazole anthelmintics in fortified beef liver.
PubMed:Ion-pairing liquid chromatographic determination of benzimidazole fungicides in foods.
PubMed:Nephrotoxicity of thiabendazole in mice depleted of glutathione by treatment with DL-buthionine sulphoximine.
PubMed:[Trichinosis: new epidemic outbreak caused by the ingestion of wild-boar sausage].
PubMed:Effects of thiabendazole on the kidneys of ICR mice.
PubMed:Glutathione and cysteine enhance and diethylmaleate reduces thiabendazole teratogenicity in mice.
PubMed:Angiostrongylus (Parastrongylus) eosinophilic meningitis.
PubMed:Synergistic effect of fungicides on resistant strains of Penicillium italicum and Penicillium digitatum.
PubMed:Improved antifungal effect of thiabendazole against Penicillium digitatum by its application to post-harvest citrus fruit in combination with carbohydrate esters of fatty acids.
PubMed:A field evaluation of benzimidazole and nonbenzimidazole drugs in a herd of dairy goats.
PubMed:Larval development test for detection of anthelmintic resistant nematodes.
PubMed:[Acute trichinosis. 193 cases in an epidemic].
PubMed:Enzyme-linked immunosorbent assay of benomyl and thiabendazole in some foods.
PubMed:Preliminary study on the use of thiabendazole in the control of common toxigenic fungi in grain feed.
PubMed:Effects of pretreatment with SKF-525A or sodium phenobarbital on thiabendazole-induced teratogenicity in ICR mice.
PubMed:Irreversible in vivo and in vitro binding of thiabendazole to tissue protein of pregnant mice.
PubMed:Anthelmintics for cattle.
PubMed:Anthelmintics for swine.
PubMed:Anthelmintics for small ruminants.
PubMed:Enhancing effect of thiabendazole on urinary bladder carcinogenesis induced by sodium o-phenylphenate in F344 rats.
PubMed:Trichinosis in Thailand during 1962-1983.
PubMed:Irreversible in vivo binding of thiabendazole to macromolecules in pregnant mice and its relation to teratogenicity.
PubMed:The maternal-foetal distribution of thiabendazole administered in two different vehicles to pregnant mice.
PubMed:Teratogenicity of thiabendazole in ICR mice.
PubMed:Determination of thiabendazole residues in marmalades by high-performance liquid chromatography.
PubMed:The microbiology of apples and apple products.
PubMed:Determination of thiabendazole residues in fruits by high-performance liquid chromatography and their confirmation after p-nitrobenzyl derivative formation.
PubMed:The fungal and bacterial flora of stored white cabbage.
PubMed:A new concentration of human intestinal capillariasis on western Luzon.
PubMed:Contents of diphenyl (DP), o-phenylphenol (OPP) and thiabendazole (TB) in imported citrus fruits and citrus fruit products.
PubMed:Non-drug-related residues in tracer studies.
PubMed:Gas-liquid chromatographic/mass spectrometric confirmatory assay for thiabendazole and 5-hydroxythiabendazole.
PubMed:Effects of a series of infections of Ostertagia circumcincta on gastric secretion of sheep.
PubMed:[Analysis of thiabendazole in citrus fruits and bananas].
PubMed:Photolysis of thiabendazole.
PubMed:Adsorption, mobility, and persistence of thiabendazole and methyl 2-benzimidazolecarbamate in soils.
PubMed:Adsorption of benzimidazole fungicides on montmorillonite and kaolinite clay surfaces.
PubMed:Bear meat trichinosis with a concomitant serologic response to Toxoplasma gondii.
PubMed:Estimation of thiabendazole in the milligram and submilligram ranges.
PubMed:Treatment of common enteric parasites.
PubMed:Metal coordination compounds of thiabendazole.
PubMed:[Trichinosis--with special reference to its occurrence and control].
PubMed:Trichinosis from bear meat and adulterated pork products: a major outbreak in British Columiba, 1971.
PubMed:Thiabendazole residues on and in citrus.
PubMed:[Human cysticercosis].
 
Notes:
2-substituted benzimidazole first introduced in 1962. it is active against a variety of nematodes and is the drug of choice for strongyloidiasis. it has central nervous system side effects and hepatototoxic potential. (from smith and reynard, textbook of pharmacology, 1992, p919) Anthelmintic, pre- and postharvest fungicide, also freq. for vet. use. Used as a postharvest treatment for bananas, plantains and oranges. Registered in Canada for control of silver scurf in stored potatoes Thiabendazole is a fungicide and parasiticide. Thiabendazole is also a chelating agent, which means that it is used medicinally to bind metals in cases of metal poisoning, such as lead poisoning, mercury poisoning or antimony poisoning. Thiabendazole is vermicidal and/or vermifugal against Ascaris lumbricoides ("common roundworm"), Strongyloides stercoralis (threadworm), Necator americanus, Ancylostoma duodenale (hookworm), Trichuris trichiura (whipworm), Ancylostoma braziliense (dog and cat hookworm), Toxocara canis, Toxocara cati (ascarids), and Enterobius vermicularis (pinworm). Thiabendazole also suppresses egg and/or larval production and may inhibit the subsequent development of those eggs or larvae which are passed in the feces.
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