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2,4-D
acetic acid, (2,4-dichlorophenoxy)-

Supplier Sponsors

CAS Number: 94-75-7Picture of molecule3D/inchi
Other(deleted CASRN):15183-39-8
ECHA EINECS - REACH Pre-Reg:202-361-1
FDA UNII: 2577AQ9262
Nikkaji Web:J3.947K
Beilstein Number:1214242
MDL:MFCD00004300
Molecular Weight:221.03742000
Formula:C8 H6 Cl2 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
Melting Point: 140.50 °C. @ 760.00 mm Hg
Boiling Point: 345.60 °C. @ 760.00 mm Hg (est)
Flash Point: 325.00 °F. TCC ( 162.80 °C. ) (est)
logP (o/w): 2.810
Soluble in:
 water, 677 mg/L @ 25 °C (exp)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
2,4-Dichlorophenoxyacetic acid
Odor: characteristic
Use: A synthetic auxin, a class of plant growth regulators; almost insoluble in water, but soluble in organic solvents; considered a dangerous good
Glentham Life Sciences
2,4-Dichlorophenoxyacetic acid
Sigma-Aldrich
For experimental / research use only.
2,4-D PESTANAL®, analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-chicken LD50 541 mg/kg
GASTROINTESTINAL: GASTRITIS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LIVER: FATTY LIVER DEGERATION
American Journal of Veterinary Research. Vol. 15, Pg. 622, 1954.

oral-dog LD50 100 mg/kg
BEHAVIORAL: STIFFNESS BEHAVIORAL: COMA
Archives of Environmental Health. Vol. 7, Pg. 202, 1963.

intraperitoneal-guinea pig LD50 666 mg/kg
BEHAVIORAL: MUSCLE WEAKNESS PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: COMA
Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 85, 1947.

oral-guinea pig LD50 469 mg/kg
American Journal of Veterinary Research. Vol. 15, Pg. 622, 1954.

oral-hamster LD50 500 mg/kg
Toxicology and Applied Pharmacology. Vol. 48, Pg. A192, 1979.

oral-human LDLo 80 mg/kg
BEHAVIORAL: COMA GASTROINTESTINAL: NAUSEA OR VOMITING BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Archives of Pathology. Vol. 94, Pg. 270, 1972.

oral-mammal (species unspecified) LD50 375 mg/kg
Science. Vol. 165, Pg. 465, 1969.

oral-man LDLo 93 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Pharmacological Reviews. Vol. 14, Pg. 225, 1962.

oral-man TDLo 2000 mg/kg
BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Archives of Toxicology. Vol. 66, Pg. 518, 1992.

oral-man TDLo 5714 mg/kg
BEHAVIORAL: COMA CARDIAC: CHANGE IN RATE LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Archives of Toxicology. Vol. 66, Pg. 518, 1992.

oral-mouse LD50 347 mg/kg
Roczniki Panstwowego Zakladu Higieny. Vol. 31, Pg. 373, 1980.

intraperitoneal-mouse LDLo 125 mg/kg
Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972.

intraperitoneal-rabbit LD50 400 mg/kg
PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: COMA
Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 85, 1947.

intravenous-rabbit LD50 400 mg/kg
BEHAVIORAL: MUSCLE WEAKNESS PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: COMA
Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 85, 1947.

oral-rabbit LDLo 800 mg/kg
Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. Vol. 12, Pg. 26, 1951.

intraperitoneal-rat LD50 666 mg/kg
PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: COMA
Journal of Industrial Hygiene and Toxicology. Vol. 29, Pg. 85, 1947.

oral-rat LD50 375 mg/kg
Farm Chemicals Handbook. Vol. -, Pg. C174, 1991.

Dermal Toxicity:
skin-rabbit LD50 1400 mg/kg
BEHAVIORAL: ATAXIA SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE
Quarterly Bulletin--Association of Food and Drug Officials of the United States. Vol. 16, Pg. 3, 1952.

skin-rat LD50 1500 mg/kg
World Review of Pest Control. Vol. 9, Pg. 119, 1970.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
herbicides / pesticides
Recommendation for 2,4-D usage levels up to:
 not for fragrance use.
 
Recommendation for 2,4-D flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Conclusion on the peer review of the pesticide risk assessment of the active substance 2,4-D
View page or View pdf

Protocol for the evaluation of data concerning the necessity of the application of herbicide active substances to control a serious danger to plant health which cannot be contained by other available means, including non-chemical methods
View page or View pdf

EPI System: View
EPA-Iris:IRIS
NIOSH International Chemical Safety Cards:search
NIOSH Pocket Guide:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):94-75-7
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :1486
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
2-(2,4-dichlorophenoxy)acetic acid
Chemidplus:0000094757
EPA/NOAA CAMEO:hazardous materials
RTECS:94-75-7
 
References:
 2-(2,4-dichlorophenoxy)acetic acid
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:94-75-7
Pubchem (cid):1486
Pubchem (sid):134971448
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
UM BBD:Search
KEGG (GenomeNet):C03664
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2918.90.4500
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 acetic acid, (2,4-dichlorophenoxy)-
 acme LV 4
 acme LV 6
 agricorn D
 agrotect
 amoxone
 brush-rhap
 butoxy-D 3: 1 Liquid emulsifiable Brushkiller LV96
 chipco turf herbicide "D"
 chloroxone
 croprider
2,4-D acid
 debroussaillant 600
 ded-weed LV-69
2-(2,4-dichlorophenoxy)acetic acid
2,4-dichlorophenoxyacetic acid
(2,4-dichlorophenyloxy)acetic acid
 dicopur
 dormone
 emulsamine BK
 emulsamine E-3
 envert DT
 fernesta
 ferxone
 foredex 75
 green cross weed-no-more "80"
 herbidal
 ipaner
 moxone
 netagrone 600
 pennamine D
 phenoxyacetic acid, 2,4-dichloro-
 planotox
 plantgard
 red devil dry weed killer
 scott's 4-XD weed control
 silvaprop 1
 tributon
 vergemaster
 verton 2D
 verton 38
 vidon 638
 weed TOX
 weed-ag-bar
 weed-B-gon
 weedone 100 emulsifiable
 weedone LV4
 
 
Notes:
an herbicide with irritant effects on the eye and the gastrointestinal system.
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