EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

coumaran
2,3-dihydrobenzo(b)furan

Supplier Sponsors

Name:2,3-dihydro-1-benzofuran
CAS Number: 496-16-2Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:207-817-3
FDA UNII:99E861415L
Nikkaji Web:J6.091G
Beilstein Number:0111928
MDL:MFCD00005855
XlogP3:2.10 (est)
Molecular Weight:120.15096000
Formula:C8 H8 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.08100 to 1.08500 @ 20.00 °C.
Pounds per Gallon - (est).: 9.005 to 9.039
Refractive Index:1.54700 to 1.55100 @ 20.00 °C.
Boiling Point: 188.00 to 189.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.748000 mm/Hg (est)
Flash Point: 152.00 °F. TCC ( 66.70 °C. ) (est)
logP (o/w): 2.140
Soluble in:
 alcohol
 water, 1491 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Santa Cruz Biotechnology
For experimental / research use only.
2,3-Dihydrobenzofuran
Sigma-Aldrich: Aldrich
For experimental / research use only.
2,3-Dihydrobenzofuran 99%
TCI AMERICA
For experimental / research use only.
2,3-Dihydrobenzofuran >98.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: natural substances and extractives
Recommendation for coumaran usage levels up to:
 not for fragrance use.
 
Recommendation for coumaran flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Cancer Citations:Search
Toxicology Citations:Search
Env. Mutagen Info. Center:Search
EPA Substance Registry Services (TSCA):496-16-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :10329
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
2,3-dihydro-1-benzofuran
Chemidplus:0000496162
 
References:
 2,3-dihydro-1-benzofuran
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):10329
Pubchem (sid):134977384
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB13815
Export Tariff Code:2932.99.7000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
EFSA Update of results on the monitoring of furan levels in food:Read Report
EFSA Previous report: Results on the monitoring of furan levels in food:Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food:Read Report
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 tea green tea
Search Trop Picture
 
Synonyms:
 benzofuran, 2,3-dihydro-
2,3-dihydro-1-benzofuran
2,3-dihydro-1-benzofurane
2,3-dihydrobenzo(b)furan
 dihydrobenzo[b]furan
2,3-dihydrobenzo[b]furan
2,3-dihydrobenzofuran
 

Articles:

PubMed:Additives initiate selective production of chemicals from biomass pyrolysis.
PubMed:A new diphenyl ether from the endophytic fungus Verticillium sp. isolated from Rehmannia glutinosa.
PubMed:Five new compounds from Rhododendron mariae Hance.
PubMed:Larvicidal activity and GC-MS analysis of flavonoids of Vitex negundo and Andrographis paniculata against two vector mosquitoes Anopheles stephensi and Aedes aegypti.
PubMed:Evidence supporting a 1,2-dioxetanone as an intermediate in the benzofuran-2(3H)-one chemiluminescence.
PubMed:The volatile profiles of a rare apple (Malus domestica Borkh.) honey: shikimic acid-pathway derivatives, terpenes, and others.
PubMed:A recyclable palladium-catalyzed synthesis of 2-methylene-2,3-dihydrobenzofuran-3-ols by cycloisomerization of 2-(1-hydroxyprop-2-ynyl)phenols in ionic liquids.
PubMed:Palladium-catalyzed hydrobenzylation of ortho-tolyl alkynyl ethers by benzylic C-H activation: remarkable alkynoxy-directing effect.
PubMed:Anti-allergic effects of mapracorat, a novel selective glucocorticoid receptor agonist, in human conjunctival fibroblasts and epithelial cells.
PubMed:Iron-catalyzed oxidative cross-coupling of phenols and alkenes.
PubMed:Melanin is crucial for growth of the black yeast Hortaea werneckii in its natural hypersaline environment.
PubMed:Reactions of o-quinone methides with pyridinium methylides: a diastereoselective synthesis of 1,2-dihydronaphtho[2,1-b]furans and 2,3-dihydrobenzofurans.
PubMed:Sequential C-H functionalization reactions for the enantioselective synthesis of highly functionalized 2,3-dihydrobenzofurans.
PubMed:An efficient and expeditious synthesis of novel 2,2-dialkyl-2,3-dihydrobenzofurans from phenols and 2,2-dialkylacetaldehydes.
PubMed:Stereocontrolled organocatalytic strategy for the synthesis of optically active 2,3-disubstituted cis-2,3-dihydrobenzofurans.
PubMed:Anti-inflammatory effects of mapracorat, a novel selective glucocorticoid receptor agonist, is partially mediated by MAP kinase phosphatase-1 (MKP-1).
PubMed:Two new compounds isolated from Liriope muscari.
PubMed:Identification and structural elucidation of two process impurities and stress degradants in darifenacin hydrobromide active pharmaceutical ingredient by LC-ESI/MS(n).
PubMed:Chemical constituents from the aerial parts of Aster koraiensis with protein glycation and aldose reductase inhibitory activities.
PubMed:Selective glucocorticoid receptor agonists for the treatment of inflammatory bowel disease: studies in mice with acute trinitrobenzene sulfonic acid colitis.
PubMed:Antimicrobial prenylated acetophenones from berries of Harrisonia abyssinica.
PubMed:Eosinophil as a cellular target of the ocular anti-allergic action of mapracorat, a novel selective glucocorticoid receptor agonist.
PubMed:Taming the Friedel-Crafts reaction: organocatalytic approach to optically active 2,3-dihydrobenzofurans.
PubMed:Bioactive phenolics from the fruits of Livistona chinensis.
PubMed:Domino reaction for the chemo- and stereoselective synthesis of trans-2,3-dihydrobenzofurans from N-thiophosphinyl imines and sulfur ylides.
PubMed:Anti-inflammatory effects of selective glucocorticoid receptor modulators are partially dependent on up-regulation of dual specificity phosphatase 1.
PubMed:Benzyl derivatives with in vitro binding affinity for human opioid and cannabinoid receptors from the fungus Eurotium repens.
PubMed:Ocular pharmacokinetics of mapracorat, a novel, selective glucocorticoid receptor agonist, in rabbits and monkeys.
PubMed:Minor new constituents from Heteroplexis micocephala.
PubMed:Thermodynamic analysis of strain in the five-membered oxygen and nitrogen heterocyclic compounds.
PubMed:Intramolecular hydroxycarbene C-H-insertion: The curious case of (o-methoxyphenyl)hydroxycarbene.
PubMed:In vivo ocular efficacy profile of mapracorat, a novel selective glucocorticoid receptor agonist, in rabbit models of ocular disease.
PubMed:Mapracorat, a novel selective glucocorticoid receptor agonist, inhibits hyperosmolar-induced cytokine release and MAPK pathways in human corneal epithelial cells.
PubMed:Phosphine-catalyzed domino reaction: highly stereoselective synthesis of trans-2,3-dihydrobenzofurans from salicyl N-thiophosphinyl imines and allylic carbonates.
PubMed:Specificity of calreticulin transacetylase to acetoxy derivatives of benzofurans: effect on the activation of platelet nitric oxide synthase.
PubMed:Quaternary ammonium (hypo)iodite catalysis for enantioselective oxidative cycloetherification.
PubMed:The first diastereoselective synthesis of cinerins A-C, PAF-antagonistic macrophyllin-type bicyclo[3.2.1]octane neolignans, using a novel Pd-catalysed oxyarylation.
PubMed:New metabolites in dibenzofuran cometabolic degradation by a biphenyl-cultivated Pseudomonas putida strain B6-2.
PubMed:BOL-303242-X, a novel selective glucocorticoid receptor agonist, with full anti-inflammatory properties in human ocular cells.
PubMed:Application of Huisgen (3+2) cycloaddition reaction: synthesis of 1-(2,3-dihydrobenzofuran-2-yl-methyl [1,2,3]-triazoles and their antitubercular evaluations.
PubMed:Reduced myocilin expression in cultured monkey trabecular meshwork cells induced by a selective glucocorticoid receptor agonist: comparison with steroids.
PubMed:Inhibitors of aldose reductase and formation of advanced glycation end-products in moutan cortex (Paeonia suffruticosa).
PubMed:2,3-Dihydro-1-benzofuran derivatives as a series of potent selective cannabinoid receptor 2 agonists: design, synthesis, and binding mode prediction through ligand-steered modeling.
PubMed:Four new compounds from Paeonia albiflora.
PubMed:Characterization of ZK 245186, a novel, selective glucocorticoid receptor agonist for the topical treatment of inflammatory skin diseases.
PubMed:Asymmetric synthesis of neolignans (-)-epi-conocarpan and (+)-conocarpan via Rh(II)-catalyzed C-H insertion process and revision of the absolute configuration of (-)-epi-conocarpan.
PubMed:Water-triggered, counter-anion-controlled, and silver-phosphines complex-catalyzed stereoselective cascade alkynylation/cyclization of terminal alkynes with salicylaldehydes.
PubMed:Leishmanicidal active constituents from Nepalese medicinal plant Tulsi (Ocimum sanctum L.).
PubMed:Synthesis and insecticidal activities and SAR studies of novel benzoheterocyclic diacylhydrazine derivatives.
PubMed:Bifunctional phosphine-catalyzed domino reaction: highly stereoselective synthesis of cis-2,3-dihydrobenzofurans from salicyl N-thiophosphinyl imines and allenes.
PubMed:Potential usefulness of D2R reporter gene imaging by IBF as gene therapy monitoring for cerebellar neurodegenerative diseases.
PubMed:Oxidation of ferulic acid by laccase: identification of the products and inhibitory effects of some dipeptides.
PubMed:A new cytotoxic prenylated dihydrobenzofuran derivative and other chemical constituents from the rhizomes of Atractylodes lancea DC.
PubMed:A Novel synthesis of 2-functionalized benzofurans by palladium-catalyzed cycloisomerization of 2-(1-hydroxyprop-2-ynyl)phenols followed by acid-catalyzed allylic isomerization or allylic nucleophilic substitution.
PubMed:Benzofuran derivatives from Eupatorium fortunei.
PubMed:Copper complexes of anionic nitrogen ligands in the amidation and imidation of aryl halides.
PubMed:Lewis acid-mediated reactions of 1-cyclopropyl-2-arylethanone derivatives with allenic ester, ethyl acetoacetate, and methyl acrylate.
PubMed:Microbial hydroxylation of o-bromophenylacetic acid: synthesis of 4-substituted-2,3-dihydrobenzofurans.
PubMed:Two new lignans from Mentha spicata L.
PubMed:Total synthesis of (-)-conocarpan and assignment of the absolute configuration by chemical methods.
PubMed:Stereoselective syntheses of the 2-Isopropenyl-2,3-dihydrobenzofuran nucleus: potential chiral building blocks for the syntheses of tremetone, hydroxytremetone, and rotenone.
PubMed:Mixed lignan-neolignans from Tarenna attenuata.
PubMed:Towards a new generation of potential antipsychotic agents combining D2 and 5-HT1A receptor activities.
PubMed:A variety of volatile compounds as markers in unifloral honey from dalmatian sage (Salvia officinalis L.).
PubMed:Six new constituents from the roots of Erythrina variegata.
PubMed:Chalcone epoxide intermediates in the syntheses of lignin-related phenylcoumarans.
PubMed:Silver-catalyzed asymmetric synthesis of 2,3-dihydrobenzofurans: a new chiral synthesis of pterocarpans.
PubMed:Fluorescence and ultraviolet absorption spectra and structure of coumaran and its ring-puckering potential energy function in the S1(pi,pi*) excited state.
PubMed:S0 ring-puckering potential energy function for coumaran.
PubMed:Evaluation of volatile low molecular weight insecticides using Drosophila melanogaster as a model.
PubMed:JNJ-10280205 and JNJ-10287069: Novel PDE5 inhibitors as clinical candidates for erectile dysfunction.
PubMed:Lignans from the bark extract of Pinus sylvestris L.
PubMed:Potent and highly selective kappa opioid receptor agonists incorporating chroman- and 2,3-dihydrobenzofuran-based constraints.
PubMed:Benzodioxole derivatives as negative effectors of plant proteases.
PubMed:Novel 2,3-dihydrobenzofuran-2-carboxylic acids: highly potent and subtype-selective PPARalpha agonists with potent hypolipidemic activity.
PubMed:Intramolecular carbolithiation of allyl o-lithioaryl ethers: a new enantioselective synthesis of functionalized 2,3-dihydrobenzofurans.
PubMed:New prenylated benzoic acid derivatives of Piper hispidum.
PubMed:Characterization of carbofuran photodegradation by-products by liquid chromatography/hybrid quadrupole time-of-flight mass spectrometry.
PubMed:Pyrroloquinolone PDE5 inhibitors with improved pharmaceutical profiles for clinical studies on erectile dysfunction.
PubMed:Phenolic compounds from Baseonema acuminatum leaves: isolation and antimicrobial activity.
PubMed:Electrochemical partial fluorination of organic compounds. 74. Efficient anodic synthesis of 2-fluoro- and 2,3-difluoro-2,3-dihydrobenzofuran derivatives.
PubMed:Application of ionic liquid halide nucleophilicity for the cleavage of ethers: a green protocol for the regeneration of phenols from ethers.
PubMed:Regioselective oxidative coupling of 4-hydroxystilbenes: synthesis of resveratrol and epsilon-viniferin (E)-dehydrodimers.
PubMed:The imidazoline NNC77-0020 affects glucose-dependent insulin, glucagon and somatostatin secretion in mouse pancreatic islets.
PubMed:Acylation of aromatic ethers over solid acid catalysts: scope of the reaction with more complex acylating agents.
PubMed:Furanonaphthoquinones, atraric acid and a benzofuran from the stem barks of Newbouldia laevis.
PubMed:Absolute structures of some naturally occurring isopropenyldihydrobenzofurans, remirol, remiridiol, angenomalin, and isoangenomalin.
PubMed:Selective alterations of the first NREM sleep cycle in humans by a dopamine D1 receptor antagonist (NNC-687).
PubMed:Synthesis and activities of oxidative metabolites of the anti-arthritic drug candidate S-2474.
PubMed:New dihydrobenzofurans and triterpenoids from roots of Microglossa pyrifolia.
PubMed:Dissimilar pharmacological responses by a new series of imidazoline derivatives at precoupled and ligand-activated alpha 2A-adrenoceptor states: evidence for effector pathway-dependent differential antagonism.
PubMed:Occupancy of dopamine D2 receptors in the mouse brain measured using ultra-high-resolution single-photon emission tomography and [123]IBF.
PubMed:Chemical and anti-platelet constituents from Formosan Zanthoxylum simulans.
PubMed:2,3,4-Trimethyl-5,7-dihydroxy-2,3-dihydrobenzofuran, a novel antioxidant, from Penicillium citrinum F5.
PubMed:CEE-03-310 CeNeS pharmaceuticals.
PubMed:Bowdenol, a new 2,3-dihydrobenzofuran constituent from Bowdichia virgilioides.
PubMed:Pyrrolidine-3-carboxylic acids as endothelin antagonists. 5. Highly selective, potent, and orally active ET(A) antagonists.
PubMed:Photoreactions of trans-1-o-Hydroxyphenyl-2-phenylcyclopropane.
PubMed:Design and Preparation of 3,3'-Disubstituted 2,2'-Bis(oxazolyl)-1,1'-binaphthyls (boxax): New Chiral Bis(oxazoline) Ligands for Catalytic Asymmetric Wacker-Type Cyclization.
PubMed:Practical asymmetric synthesis of a selective endothelin A receptor (ETA) antagonist.
PubMed:Effects of HSP-117, a novel tachykinin NK1-receptor antagonist, on cisplatin-induced pica as a new evaluation of delayed emesis in rats.
PubMed:The antioxidant profile of 2,3-dihydrobenzo[b]furan-5-ol and its 1-thio, 1-seleno, and 1-telluro analogues.
PubMed:Chiroptical properties of 2,3-dihydrobenzo[b]furan and chromane chromophores in naturally occurring O-heterocycles.
PubMed:Regioselective dimerization of ferulic acid in a micellar solution.
PubMed:Cytotoxicity and radical intensity of eugenol, isoeugenol or related dimers.
PubMed:ESR study on the antioxidant activity of TAK-218 in biological model membranes.
PubMed:[Phase 2 clinical study of 123I-IBF, a dopamine D2 receptor imaging agent, to evaluate clinical efficacy and safety in Parkinson's disease and Parkinson syndromes].
PubMed:Clozapine: dopamine D1 receptor agonism in the prefrontal cortex as the code to decipher a Rosetta stone of antipsychotic drugs.
PubMed:PET studies of binding competition between endogenous dopamine and the D1 radiotracer [11C]NNC 756.
PubMed:Reactivity of Cl-P(+)-Cl toward cyclic organic ethers.
PubMed:[Phase 1 clinical study of 123I-IBF, a new radioligand for evaluating dopamine D2 receptor with SPECT (I); biodistribution and dosimetry].
PubMed:Ferulic acid dehydrodimers from wheat bran: isolation, purification and antioxidant properties of 8-O-4-diferulic acid.
PubMed:Stereoisomers of 3-(2,3-dihydrobenzofuran-2-yl)quinuclidine: preparation and muscarinic receptor affinities.
PubMed:Prenylated benzoic acids from rapanea myricoides
PubMed:Comparison of the in vitro and in vivo profiles of tolterodine with those of subtype-selective muscarinic receptor antagonists.
PubMed:Lack of effect of the dopamine D1 antagonist, NNC 01-0687, on unstimulated and stimulated release of anterior pituitary hormones in males.
PubMed:Stereoselective uptake of an organic anion across the renal basolateral membrane in isolated perfused rat kidney.
PubMed:Dihydrexidine produces hypothermia in rats via activation of dopamine D1 receptors.
PubMed:Dihydrobenzofuran analogues of hallucinogens. 4. Mescaline derivatives.
PubMed:Applications of High-Temperature Aqueous Media for Synthetic Organic Reactions.
PubMed:5-aminocoumarans: dual inhibitors of lipid peroxidation and dopamine release with protective effects against central nervous system trauma and ischemia.
PubMed:Characterisation of [3H]-darifenacin as a novel radioligand for the study of muscarinic M3 receptors.
PubMed:An Aspergillus niger esterase (ferulic acid esterase III) and a recombinant Pseudomonas fluorescens subsp. cellulosa esterase (Xy1D) release a 5-5' ferulic dehydrodimer (diferulic acid) from barley and wheat cell walls.
PubMed:Reactions of Allyl Phenyl Ether in High-Temperature Water with Conventional and Microwave Heating.
PubMed:Stereoselective syntheses of substituted pterocarpans with anti-HIV activity, and 5-aza-/5-thia-pterocarpan and 2-aryl-2,3-dihydrobenzofuran analogues.
PubMed:Further evidence for clozapine as a dopamine D1 receptor agonist.
PubMed:Potent inhibitors of acyl-CoA:cholesterol acyltransferase. 2. Structure-activity relationships of novel N-(2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)amides.
PubMed:[Synthesis of certain derivatives of 5-methoxy-3-[(benzazole-2-yl) thioacetylamino]-2,3-dihydrobenzofuran and research on their antihypertensive activities].
PubMed:NNC 01-0687, a selective dopamine D1 receptor antagonist, in the treatment of schizophrenia.
PubMed:Tolerability, safety and pharmacokinetics of single dose and multiple dosing of the selective D1 antagonist NNC 01-0687 in healthy subjects.
PubMed:Desaturation, dioxygenation, and monooxygenation reactions catalyzed by naphthalene dioxygenase from Pseudomonas sp. strain 9816-4.
PubMed:Stereoselective renal tubular secretion of an organic anion in the isolated perfused rat kidney.
PubMed:[Synthesis of certain derivatives of methoxy-5-[(benzazole-2-yl)thioacetylamino]-3-dihydro-2,3-benzofuran and research on their antihypertensive activity].
PubMed:Synthesis and structure-activity relationships of 2,3-dihydrobenzofuran-7-carboxamide derivatives as potent serotonin-3 (5-HT3) receptor antagonists.
PubMed:Localization of IBF as a D-2 dopamine receptor imaging agent in nonhuman primates.
PubMed:Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogues of 3,4-(methylenedioxy)amphetamine.
PubMed:[11C]NNC 687 and [11C]NNC 756, dopamine D-1 receptor ligands. Preparation, autoradiography and PET investigation in monkey.
PubMed:Enantiomer-enantiomer interaction of a uricosuric antihypertensive diuretic (DBCA) in renal tubular secretion and stereoselective inhibition by probenecid in the cynomolgus monkey.
PubMed:New fluorinated dopamine D2 ligands with benzofuran skeleton. The synthesis and in vitro evaluation.
PubMed:PET examination of [11C]NNC 687 and [11C]NNC 756 as new radioligands for the D1-dopamine receptor.
PubMed:Stereoselective pharmacokinetics of a novel uricosuric antihypertensive diuretic in rats: pharmacokinetic interaction between enantiomers.
PubMed:NNC-112, NNC-687 and NNC-756, new selective and highly potent dopamine D1 receptor antagonists.
PubMed:Dopamine receptor occupancy in vivo: behavioral correlates using NNC-112, NNC-687 and NNC-756, new selective dopamine D1 receptor antagonists.
PubMed:Determination of (+)-5-(2,3-dihydrobenzofuran-7-yl)-3-methyl-8-nitro-2,3,4,5- tetrahydro-1H-3-benzazepin-7-ol (NNC 01-0687), a novel dopamine D-1 receptor antagonist, in plasma by solid-phase extraction and high-performance liquid chromatography.
PubMed:Stereoselective disposition of S-8666, a novel uricosuric antihypertensive diuretic, and its N-monodemethylated metabolite in a perfused rat liver preparation. Effect of protein binding on the kinetics of S-8666.
PubMed:Stereoselective conjugation of a uricosuric diuretic with glutathione by glutathione transferase 3-3.
PubMed:Identification of the major metabolites of [3H]-(+)-8-chloro-5-(2,3- dihydrobenzofuran-7-yl)-7-methoxymethyloxy-3-methyl-2,3,4,5-tetrahydro- 1H-3- benzazepine in rats.
PubMed:Glucuronidation of the dopamine D-1 receptor antagonists NNC 0756 and NNC 0772 in liver microsomes.
PubMed:Protective action of a new benzofuran derivative on lipid peroxidation and sulphydryl groups oxidation.
PubMed:High-performance liquid chromatographic method for simultaneous determination of enantiomers of 5-dimethylsulphamoyl-6,7-dichloro-2-dihydrobenzofuran-2, carboxylic acid and its N-monodemethyl metabolite in monkey plasma and urine after chiral derivatization.
PubMed:Pseudoperoxidase activity of 5-lipoxygenase stimulated by potent benzofuranol and N-hydroxyurea inhibitors of the lipoxygenase reaction.
PubMed:Structure determination of a diuretic-glutathione conjugate by mass and n.m.r. spectrometry.
PubMed:2,3-Dihydrobenzofuran analogues of hallucinogenic phenethylamines.
PubMed:Antidopaminergic effects of the stereoisomers of N-[(1-alkyl-2- pyrrolidinyl)methyl]-5-sulfamoylbenzamides and -2,3-dihydrobenzofuran-7-carboxamides.
PubMed:Comparative pharmacokinetics of sulpiride and N-[(1-butyl-2-pyrrolidinyl)methyl]-2-methyl-5-sulfamoyl-2,3- dihydrobenzofuran-7-carboxamide hydrochloride, a new lipophilic substituted benzamide in rats.
PubMed:Potential antipsychotic agents. 7. Synthesis and antidopaminergic properties of the atypical highly potent (S)-5-bromo-2,3-dimethoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]benzamide and related compounds. A comparative study.
PubMed:Potential neuroleptic agents, N-[(2-pyrrolidinyl)methyl]-2,3-dihydrobenzofuran-7-carboxamide derivatives.
PubMed:The characterization of IBF as a new selective dopamine D-2 receptor imaging agent.
PubMed:[Neuroleptic properties of Y-20024, a new benzofurancarboxamide derivative].
PubMed:Studies on uricosuric diuretics. II. 6,7-Dichloro-4-nitro-, 6,7-dichloro-4-sulfamoyl- and 6,7-dichloro-4-acyl-2,3-dihydrobenzofuran-2-carboxylic acids.
PubMed:Studies on uricosuric diuretics. I. 6,7-Dichloro-5-sulfamoyl-2,3-dihydrobenzofuran-2-carboxylic acids.
PubMed:A new uricosuric diuretic, S-8666, in rats and chimpanzees.
PubMed:Comparative antiaggregatory activity in human platelets of a benzopyranone aci-reductone, clofibric acid, and a 2,3-dihydrobenzofuran analogue.
PubMed:Enhancement of epoxide hydrolase activity in hepatic microsomes of mice given heterocyclic compounds.
PubMed:A comparative study of the locomotor activity effects of apomorphine and the "atypical dopamine agonists" (piribedil and S3608).
PubMed:Synthesis and evaluation of 2,3-dihydrobenzofuran analogues of the hallucinogen 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane: drug discrimination studies in rats.
PubMed:[(Aminomethyl)aryloxy]acetic acid esters. A new class of high-ceiling diuretics. 4. Substituted 6,7-dichloro-2,3-dihydrobenzofurans derived by ring annelation.
PubMed:Efforts toward combined analgesic/antidepressants: synthesis and evaluation of (3-aryl-2,3-dihydrobenzofuran-3-yl)alkanamines.
PubMed:[Chemotherapeutic studies on schistosomiasis. XIV. Synthesis of coumaran derivatives and its analogs].
PubMed:Differential labelling of dopamine receptors in rat brain in vivo: comparison of [3H]piribedil, [3H]S 3608 and [3H]N,n-propylnorapomorphine.
PubMed:2,3-Dihydrobenzofuran-2-ones: a new class of highly potent antiinflammatory agents.
PubMed:Urinary metabolites of 3,5-di-(1-[13C]methyl-1-methylethyl)4-hydroxytoluene (BHT-13C) in man.
PubMed:Role of Phenolic Inhibitors in Peroxidase-mediated Degradation of Indole-3-acetic Acid.
PubMed:Comparative antilipidemic effects of various ethyl 5-substituted benzofuran-, 2,3-dihydrobenzofuran-, and 3(2H)-benzofuranone-2-carboxylate analogs of clofibrate in a triton hyperlipidemic rat model.
PubMed:Antiinflammatory activity of some 2,3-dihydrobenzofuran-5-acetic acids and related compounds.
PubMed:A new central direct dopaminergic stimulant: 1-(Coumaran-5-yl methyl)-4-(2-thiazolyl) piperazine hydrochloride (S 3608).
PubMed:Studies on the central action of 2-methylamino-methyl 2,3-dihydrobenzofuran (EPS-4032). l. EEG studies in rabbits.
PubMed:The peroxidase-catalysed oxidation of a chalcone and its possible physiological significance.
PubMed:MOde of action of analgesic effect of 2-methylaminomethyl-2,3-dihydrobenzofuran (EPS-4032).
PubMed:[Analgesic effect of 2-methylaminoethyl 2,3-dihydrobenzofuran (EPS-4032); mode of action in mice].
PubMed:Studies on benzoheterocyclic derivatives (IX). Structure-activity relations hips of 5 or 7 substituted 2-(3'-alkoxypropylaminomethyl) 2,3-dihydrobenzofuran analogues on analgesic, spinal reflex depressing and adrenergic -blocking effects.
PubMed:Synthesis and structure studies on benzofuran and coumaran derivatives with choleretic activity.
PubMed:[Studies on chemotherapeutic drugs. IV. Synthesis of nitrofuran derivatives. (3). Preparation of 2-(5-nitro-2-furfurylidene)-3-oxo-2,3-dihydrobenzofuran (or thiophene) derivatives and their antibacterial activities].
PubMed:Synthesis of grisan and coumaran-3-one derivatives with potential insect-repellent properties.
PubMed:[Research in the 1,4-benzodyoxane and 2,3-dihydrobenzofuran series. Synthesis of 1,2-ethandiol monocarbamates].
PubMed:THE ADRENERGIC-NEURONE BLOCKING ACTION OF SOME COUMARAN COMPOUNDS.
PubMed:Morphine studies; 2-keto-7-methoxy-2,3-dihydrobenzofuran derivatives.
PubMed:Vitamin E; the coumaran isomer of alpha-tocopherol.
 
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