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hydroxyethyl tromethamine
1,3-propanediol, 2-(bis(2-hydroxyethyl)amino)-2-(hydroxymethyl)-


Name: 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol
CAS Number: 6976-37-0Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 230-237-7
Nikkaji Web: J135.733F
Beilstein Number: 2205275
MDL: MFCD00002853
XlogP3-AA: -3.30 (est)
Molecular Weight: 209.24243000
Formula: C8 H19 N O5
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: buffering agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
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Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 466.20 °C. @ 760.00 mm Hg (est)
Flash Point: 550.00 °F. TCC ( 288.00 °C. ) (est)
logP (o/w): -0.670 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: buffering agents
Santa Cruz Biotechnology
For experimental / research use only.
BIS-Tris ≥98%
Sigma-Aldrich: Sigma
For experimental / research use only.
BIS-TRIS ≥98.0% (titration)
For experimental / research use only.
Bis(2-hydroxyethyl)aminotris(hydroxymethyl)methane [Good's buffer component for biological research] >99.0%(HPLC)(T)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
Category: buffering agents
Recommendation for hydroxyethyl tromethamine usage levels up to:
 not for fragrance use.
Recommendation for hydroxyethyl tromethamine flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 6976-37-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 81462
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
Chemidplus: 0006976370
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 81462
Pubchem (sid): 135038734
Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2922.19.5000
ChemSpider: View
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other): note
 not found in nature
1,3-propanediol, 2-(bis(2-hydroxyethyl)amino)-2-(hydroxymethyl)-
None found
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