EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

12-hydroxydodecanoic acid
sabinic acid

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Name:12-hydroxydodecanoic acid
CAS Number: 505-95-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:208-025-0
Nikkaji Web:J182.260H
Beilstein Number:1238370
XlogP3:3.60 (est)
Molecular Weight:216.32088000
Formula:C12 H24 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Appearance:white powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 85.00 to 88.00 °C. @ 760.00 mm Hg
Boiling Point: 359.00 to 360.00 °C. @ 760.00 mm Hg (est)
Flash Point: 365.00 °F. TCC ( 185.20 °C. ) (est)
logP (o/w): 2.866 (est)
Soluble in:
 water, 278 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
BOC Sciences
For experimental / research use only.
Matrix Scientific
For experimental / research use only.
12-Hydroxydodecanoic acid, 95+%
Santa Cruz Biotechnology
For experimental / research use only.
12-Hydroxydodecanoic Acid ≥96%
Sigma-Aldrich: Aldrich
For experimental / research use only.
12-Hydroxydodecanoic Acid 97%
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
natural substances and extractives
Recommendation for 12-hydroxydodecanoic acid usage levels up to:
 not for fragrance use.
Recommendation for 12-hydroxydodecanoic acid flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :79034
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
12-hydroxydodecanoic acid
 12-hydroxydodecanoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):79034
Pubchem (sid):135036098
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C08317
HMDB (The Human Metabolome Database):HMDB02059
Export Tariff Code:2918.19.9000
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
Search Picture
 dodecanoic acid, 12-hydroxy-
12-hydroxy lauric acid
12-hydroxy-dodecanoic acid
12-hydroxylauric acid
 lauric acid, 12-hydroxy-
 sabinic acid


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12-hydroxydodecanoic acid is the substrate of the human glutathione-dependent formaldehyde dehydrogenase (EC1.1.1.1) . The enzyme that catalyzes the conversion of alcohols to aldehydes is a zinc-containing dimeric enzyme responsible for the oxidation of long-chain alcohols and omega-hydroxy fatty acids. (OMIM) The human glutathione-dependent formaldehyde dehydrogenase is unique among the structurally studied members of the alcohol dehydrogenase family in that it follows a random bi kinetic mechanism forming a binary complex, and a ternary complex with NAD+. (PMID 12196016) [HMDB]
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