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1,4-cyclohexadiene
cyclohexa-1,4-diene

Supplier Sponsors

Name:cyclohexa-1,4-diene
CAS Number: 628-41-1Picture of molecule3D/inchi
Other(deleted CASRN):33004-08-9
ECHA EINECS - REACH Pre-Reg:211-043-1
FDA UNII: 0F8Z5909QZ
Nikkaji Web:J95.801H
Beilstein Number:1900733
MDL:MFCD00001535
XlogP3:2.30 (est)
Molecular Weight:80.12976000
Formula:C6 H8
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.85500 to 0.85800 @ 20.00 °C.
Pounds per Gallon - (est).: 7.123 to 7.148
Refractive Index:1.47100 to 1.47300 @ 20.00 °C.
Boiling Point: 85.50 °C. @ 760.00 mm Hg
Vapor Pressure:77.400000 mmHg @ 25.00 °C. (est)
Flash Point: 20.00 °F. TCC ( -6.67 °C. )
logP (o/w): 2.300
Soluble in:
 water, 700 mg/L @ 25 °C (exp)
 water, 412.3 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Santa Cruz Biotechnology
For experimental / research use only.
1,4-Cyclohexadiene
Sigma-Aldrich: Aldrich
For experimental / research use only.
1,4-Cyclohexadiene 97%
TCI AMERICA
For experimental / research use only.
1,4-Cyclohexadiene (stabilized with BHT) >98.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for 1,4-cyclohexadiene usage levels up to:
 not for fragrance use.
 
Recommendation for 1,4-cyclohexadiene flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):628-41-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :12343
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
cyclohexa-1,4-diene
Chemidplus:0000628411
 
References:
 cyclohexa-1,4-diene
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:628-41-1
Pubchem (cid):12343
Pubchem (sid):134975830
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2902.19.0050
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
 cyclohexa-1,4-diene
 

Articles:

PubMed:1,4-Cyclohexadienes-Easy Access to a Versatile Building Block via Transition-Metal-Catalysed Diels-Alder Reactions.
PubMed:Substrate dependent reaction channels of the Wolff-Kishner reduction reaction: A theoretical study.
PubMed:1,4-Bis(trimethylsilyl)-1,4-diaza-2,5-cyclohexadienes as strong salt-free reductants for generating low-valent early transition metals with electron-donating ligands.
PubMed:Kinetic and mechanistic studies of carbon-to-metal hydrogen atom transfer involving Os-centered radicals: evidence for tunneling.
PubMed:H2O2-dependent substrate oxidation by an engineered diiron site in a bacterial hemerythrin.
PubMed:Dichotomous hydrogen atom transfer vs proton-coupled electron transfer during activation of X-H bonds (X = C, N, O) by nonheme iron-oxo complexes of variable basicity.
PubMed:C-H activation by a diselenido dinickel(II) complex.
PubMed:Signatures in vibrational and UV-visible absorption spectra for identifying cyclic hydrocarbons by graphene fragments.
PubMed:Organocatalytic asymmetric desymmetrization: efficient construction of spirocyclic oxindoles bearing a unique all-carbon quaternary stereogenic center via sulfa-Michael addition.
PubMed:Zero-point corrections for isotropic coupling constants for cyclohexadienyl radical, C₆H₇ and C₆H₆Mu: beyond the bond length change approximation.
PubMed:Matrix isolation study of the ozonolysis of 1,3- and 1,4-cyclohexadiene: identification of novel reaction pathways.
PubMed:Noninteracting, vicinal frustrated P/B-Lewis pair at the norbornane framework: synthesis, characterization, and reactions.
PubMed:Salt-free reducing reagent of bis(trimethylsilyl)cyclohexadiene mediates multielectron reduction of chloride complexes of W(VI) and W(IV).
PubMed:An aerobic oxidation/homolytic substitution-cascade for stereoselective methylsulfanyl-cyclization of 4-pentenols.
PubMed:Utilizing redox-mediated Bergman cyclization toward the development of dual-action metalloenediyne therapeutics.
PubMed:Stereoselective syntheses of racemic quercitols and bromoquercitols starting from cyclohexa-1,4-diene: gala-, epi-, muco-, and neo-quercitol.
PubMed:A mononuclear non-heme manganese(IV)-oxo complex binding redox-inactive metal ions.
PubMed:Effect of metal ions on the reactions of the cumyloxyl radical with hydrogen atom donors. Fine control on hydrogen abstraction reactivity determined by Lewis acid-base interactions.
PubMed:Copper complexes of the non-innocent β-diketiminate ligand containing phenol groups.
PubMed:Crystal structure of the hexachlorocyclohexane dehydrochlorinase (LinA-type2): mutational analysis, thermostability and enantioselectivity.
PubMed:Catalytic desymmetrization of cyclohexadienes by asymmetric bromolactonization.
PubMed:Biodegradation of lindane using a novel yeast strain, Rhodotorula sp. VITJzN03 isolated from agricultural soil.
PubMed:Syntheses, thermal reactivities, and computational studies of aryl-fused quinoxalenediynes: effect of extended benzannelation on Bergman cyclization energetics.
PubMed:Transient X-ray fragmentation: probing a prototypical photoinduced ring opening.
PubMed:Valuable new cyclohexadiene building blocks from cationic η5-iron-carbonyl complexes derived from a microbial arene oxidation product.
PubMed:The role of group 14 element hydrides in the activation of C-H bonds in cyclic olefins.
PubMed:Ligand effects on hydrogen atom transfer from hydrocarbons to three-coordinate iron imides.
PubMed:Correlating DFT-calculated energy barriers to experiments in nonheme octahedral Fe(IV)O species.
PubMed:N,N-addition of frustrated Lewis pairs to nitric oxide: an easy entry to a unique family of aminoxyl radicals.
PubMed:A new method for investigating infrared spectra of protonated benzene (C6H7+) and cyclohexadienyl radical (c-C6H7) using para-hydrogen.
PubMed:Hyaladione, an S-methyl cyclohexadiene-dione from Hyalangium minutum.
PubMed:Reactions of neutral gas-phase yttrium atoms with two cyclohexadiene isomers.
PubMed:Shapeshifting: ligation by 1,4-cyclohexadiene induces a structural change in Ag5(+).
PubMed:Nonheme iron-oxo and -superoxo reactivities: O2 binding and spin inversion probability matter.
PubMed:Comparison of metabolomic profiles obtained using chemical ionization and electron ionization MS in exhaled breath.
PubMed:Modulation of volatile organic compound formation in the Mycodiesel-producing endophyte Hypoxylon sp. CI-4.
PubMed:Selective molecular sequestration with concurrent natural product functionalization and derivatization: from crude natural product extracts to a single natural product derivative in one step.
PubMed:Unravelling the details of vitamin D photosynthesis by non-adiabatic molecular dynamics simulations.
PubMed:Enzymes involved in the biodegradation of hexachlorocyclohexane: a mini review.
PubMed:Carbon radical generation by d0 tantalum complexes with α-diimine ligands through ligand-centered redox processes.
PubMed:Shifting from Ziegler-Natta to Philips-type catalyst? A simple and safe access to reduced titanium systems for ethylene polymerization.
PubMed:A mechanistic analysis of the Birch Reduction.
PubMed:Oxidative properties of a nonheme Ni(II)(O2) complex: Reactivity patterns for C-H activation, aromatic hydroxylation and heteroatom oxidation.
PubMed:Heterogeneous reaction of suspended phosmet particles with NO3 radicals.
PubMed:Through-bond interactions and the localization of excited-state dynamics.
PubMed:Reactivity of copper(II)-alkylperoxo complexes.
PubMed:Fine-tuning alkyne cycloadditions: Insights into photochemistry responsible for the double-strand DNA cleavage via structural perturbations in diaryl alkyne conjugates.
PubMed:Probing lipid peroxidation by using linoleic acid and benzophenone.
PubMed:Photobehavior of mixed nπ*/ππ* triplets: simultaneous detection of the two transients, solvent-dependent hydrogen abstraction, and reequilibration upon protein binding.
PubMed:C-H activation of cycloalkenes by dimetallynes (M = Ge, Sn) under ambient conditions.
PubMed:Cytotoxic 1,2-dialkynylimidazole-based aza-enediynes: aza-Bergman rearrangement rates do not predict cytotoxicity.
PubMed:Synthesis and Polymerization of Renewable 1,3-Cyclohexadiene Using Metathesis, Isomerization, and Cascade Reactions with Late-metal Catalysts.
PubMed:Opportunistic use of tetrachloroaurate photolysis in the generation of reductive species for the production of gold nanostructures.
PubMed:Kinetic solvent effects on hydrogen abstraction reactions from carbon by the cumyloxyl radical. The importance of solvent hydrogen-bond interactions with the substrate and the abstracting radical.
PubMed:Surface-initiated ring-opening metathesis polymerization in the vapor phase: an efficient method for grafting cyclic olefins with low strain energies.
PubMed:Functionalized tetrahydrofurans from alkenols and olefins/alkynes via aerobic oxidation-radical addition cascades.
PubMed:Breathing and twisting: an investigation of framework deformation and guest packing in single crystals of a microporous vanadium benzenedicarboxylate.
PubMed:Clean photodecomposition of 1-methyl-4-phenyl-1H-tetrazole-5(4H)-thiones to carbodiimides proceeds via a biradical.
PubMed:Diffusion controlled hydrogen atom abstraction from tertiary amines by the benzyloxyl radical. The importance of C-H/N hydrogen bonding.
PubMed:Hyperaromatic stabilization of arenium ions.
PubMed:Hypoxylon sp., an endophyte of Persea indica, producing 1,8-cineole and other bioactive volatiles with fuel potential.
PubMed:Synthesis of enantiopure trans-N-Boc-3-aminobicyclo[2.2.2]octane-2-carboxylic acids and their bicyclic 1,3-amino alcohol derivatives via the [4+2] cycloaddition of 1,3-cyclohexadiene to a chiral β-nitroacrylate.
PubMed:Dual reactivity of hydroxy- and methoxy- substituted o-quinone methides in aqueous solutions: hydration versus tautomerization.
PubMed:Transforming terpene feedstock into polyketide architecture.
PubMed:Crystal structure of γ-hexachlorocyclohexane Dehydrochlorinase LinA from Sphingobium japonicum UT26.
PubMed:Accessing the antipodal series in microbial arene oxidation: a novel diene rearrangement induced by tricarbonyliron(0) complexation.
PubMed:Kinetic solvent effects on hydrogen abstraction reactions from carbon by the cumyloxyl radical. The role of hydrogen bonding.
PubMed:A laser flash photolysis and theoretical study of hydrogen abstraction from phenols by triplet alpha-naphthoflavone.
PubMed:The crystal structure of a high-spin oxoiron(IV) complex and characterization of its self-decay pathway.
PubMed:Regioselective synthesis of aniline-derived 1,3- and Ci-symmetric 1,4-diols from trans-1,4-cyclohexadiene dioxide.
PubMed:Conformationally gated fragmentations and rearrangements promoted by interception of the Bergman cyclization through intramolecular H-abstraction: a possible mechanism of auto-resistance to natural enediyne antibiotics?
PubMed:Reaction of a (Salen)ruthenium(VI) nitrido complex with thiols. C-H bond activation by (Salen)ruthenium(IV) sulfilamido species.
PubMed:A functional genomics approach to tanshinone biosynthesis provides stereochemical insights.
PubMed:Aromatic compounds as synthons for 1,3-dicarbonyl derivatives.
PubMed:Iridium(III) catalyzed diastereo- and enantioselective C-H bond functionalization.
PubMed:Reductive and brominative termination of alkenol cyclization in aerobic cobalt-catalyzed reactions.
PubMed:Studies towards the total synthesis of lycoposerramine A. Synthesis of a model for the tetracyclic core.
PubMed:Crystallization and preliminary X-ray analysis of gamma-hexachlorocyclohexane dehydrochlorinase LinA from Sphingobium japonicum UT26.
PubMed:Mechanistic insight into the palladium-catalyzed 1,4-oxidation of 1,3-dienes to 1,4-dicarboxy-alk-2-enes.
PubMed:Aliphatic C-H bond activation initiated by a (mu-eta2:eta2-peroxo)dicopper(II) complex in comparison with cumylperoxyl radical.
PubMed:Enthalpy of formation of the cyclohexadienyl radical and the C-H bond enthalpy of 1,4-cyclohexadiene: an experimental and computational re-evaluation.
PubMed:Desymmetrization of hydrazinocyclohexadienes: a new approach for the synthesis of polyhydroxylated aminocyclohexanes.
PubMed:Effect of imidazole and phenolate axial ligands on the electronic structure and reactivity of oxoiron(IV) porphyrin pi-cation radical complexes: drastic increase in oxo-transfer and hydrogen abstraction reactivities.
PubMed:Enantioselective reactions of donor/acceptor carbenoids derived from alpha-aryl-alpha-diazoketones.
PubMed:Photochemical strategies for the synthesis of gold nanoparticles from Au(III) and Au(I) using photoinduced free radical generation.
PubMed:Enol formation and ring-opening in OH-initiated oxidation of cycloalkenes.
PubMed:Directed epoxidation of cyclohexa-1,4-dienes-stereoselective formation of up to six contiguous stereogenic centres.
PubMed:Combined experimental and theoretical approach to understand the reactivity of a mononuclear Cu(II)-hydroperoxo complex in oxygenation reactions.
PubMed:Reaction of phenols with the 2,2-diphenyl-1-picrylhydrazyl radical. Kinetics and DFT calculations applied to determine ArO-H bond dissociation enthalpies and reaction mechanism.
PubMed:Characterization, reactivity and photosensitizing properties of the triplet excited state of alpha-lapachone.
PubMed:Expansion by contraction: diversifying the photochemical reactivity scope of diazo-oxochlorins toward development of in situ alkylating agents.
PubMed:Simultaneous determination of trace uranium(VI) and zinc(II) by adsorptive cathodic stripping voltammetry with aluminon ligand.
PubMed:Thermal C1-C5 diradical cyclization of enediynes.
PubMed:Catalytic tuning of a phosphinoethane ligand for enhanced C-H activation.
PubMed:Transition states for the dimerization of 1,3-cyclohexadiene: a DFT, CASPT2, and CBS-QB3 quantum mechanical investigation.
PubMed:Energetic differences between the five- and six-membered ring hydrocarbons: strain energies in the parent and radical molecules.
PubMed:Theoretical study of multiphoton ionization of cyclohexadienes and unimolecular decomposition of their mono- and dications.
PubMed:Laser flash photolysis study of the triplet reactivity of beta-lapachones.
PubMed:A new 18F-labeled fluoroacetylmorpholino derivative of vesamicol for neuroimaging of the vesicular acetylcholine transporter.
PubMed:Chiral version of the Burgess reagent and its reactions with oxiranes: application to the formal enantiodivergent synthesis of balanol.
PubMed:A two-state reactivity rationale for counterintuitive axial ligand effects on the C-H activation reactivity of nonheme FeIV=O oxidants.
PubMed:Chemical synthesis and biological evaluation of a NAD(P)H:quinone oxidoreductase-1 targeted tripartite quinone drug delivery system.
PubMed:On the mechanism and kinetics of radical reactions of epoxyketones and epoxynitriles induced by titanocene chloride.
PubMed:Fluorescent and affinity-based tools to detect cysteine sulfenic acid formation in proteins.
PubMed:An efficient one-pot synthesis of tethered cyclohexadiene enaminonitriles from methyl-ketones: an effective route to quinazolines.
PubMed:Aqueous Ti(IV)-catalyzed Diels-Alder reaction.
PubMed:Vibrational characterization of different benzene phases on flat and vicinal Si(100) surfaces.
PubMed:Energetics of the allyl group.
PubMed:Concise asymmetric total synthesis of scyphostatin, a potent inhibitor of neutral sphingomyelinase.
PubMed:Analysis of the role of LinA and LinB in biodegradation of delta-hexachlorocyclohexane.
PubMed:Iodocyclization reactions for the desymmetrization of cyclohexa-1,4-dienes.
PubMed:(N-heterocyclic carbene)gold(I)-catalyzed cycloisomerization of cyclohexadienyl alkynes to Tetracyclo[3.3.0.0(2,8).0(4,6)]octanes.
PubMed:N,N-Di(4-halophenyl)nitrenium ions: nucleophilic trapping, aromatic substitution, and hydrogen atom transfer.
PubMed:Synthesis of multiply substituted alkylidene silacyclohexadiene derivatives via palladium-catalyzed insertion of alkynes into alkylidene silacyclobutenes.
PubMed:Total synthesis of the chlorinated marine natural product dysamide B.
PubMed:Dynamics of surface catalyzed reactions; the roles of surface defects, surface diffusion, and hot electrons.
PubMed:Probing weak molecular orbital interactions in non-conjugated diene molecules by means of near-edge X-ray absorption spectroscopy.
PubMed:Hydrogen atom abstraction by a high-valent manganese(V)-oxo corrolazine.
PubMed:Synthesis of 1,4-cyclohexadiene-based acetylenic macrocycles with Cadiot-Chodkiewicz coupling. Structure of a tub-shaped tetrameric container.
PubMed:Ionizing radiation-induced destruction of benzene and dienes in aqueous media.
PubMed:Tandem photocycloaddition-retro-mannich fragmentation of enaminones. A route to spiropyrrolines and the tetracyclic core of koumine.
PubMed:Intramolecular bromo-amination of 1,4-cyclohexadiene aminal: one-pot discrimination of two olefins and concise asymmetric synthesis of (-)-gamma-lycorane.
PubMed:A new approach to promoting sluggish Diels-Alder reactions: dihapto-coordination of the diene.
PubMed:Spectroscopic analysis of small organic molecules: a comprehensive near-edge x-ray-absorption fine-structure study of C6-ring-containing molecules.
PubMed:Ortho effect in the Bergman cyclization: comparison of experimental approaches and dissection of cycloaromatization kinetics.
PubMed:Doubly protonated benzene in the gas phase.
PubMed:A transition-metal-catalyzed enediyne cycloaromatization.
PubMed:Carbon-to-metal hydrogen atom transfer: direct observation using time-resolved infrared spectroscopy.
PubMed:Anharmonic compression of the glitter lattice.
PubMed:Photosensitized conversion of 9,10-deoxytridachione to photodeoxytridachione.
PubMed:Evolution of functional cyclohexadiene-based synthetic reagents: the importance of becoming aromatic.
PubMed:A terminal Ni(III)-imide with diverse reactivity pathways.
PubMed:Bergman cyclization of sterically hindered substrates and observation of phenyl-shifted products.
PubMed:Triplet acetylenes as synthetic equivalents of 1,2-bicarbenes: phantom n,pi state controls reactivity in triplet photocycloaddition.
PubMed:A kinetics and mechanistic study of the OH and NO2 initiated oxidation of cyclohexa-1,3-diene in the gas phase.
PubMed:Dienophile twisting and substituent effects influence reaction rates of intramolecular Diels-Alder cycloadditions: a DFT study.
PubMed:1,4-Addition of benzene to a dihydrocyclopent[a]indene diradical: synthesis and DFT study.
PubMed:Controlling both ground- and excited-state thermal barriers to Bergman cyclization with alkyne termini substitution.
PubMed:IKCa-channel blockers. Part 2: discovery of cyclohexadienes.
PubMed:Benzene formation during aquasonolysis of selected cyclic C6Hx hydrocarbons.
PubMed:Sonochemical reaction of selected cyclic C6Hx hydrocarbons in organic solvents.
PubMed:Laser-induced fluorescence of cyclohexadienyl (c-C6H7) radical in the gas phase.
PubMed:Stereoselective synthesis of (+)-nephrosteranic acid, (+)-trans-cognac lactone, and (+)-trans-whisky lactone using a chiral cyclohexadienyl Ti compound.
PubMed:Triterpenoid total synthesis. Synthesis and absolute configuration of mispyric acid.
PubMed:A new synthesis of pentafluorosulfanylbenzene.
PubMed:Ring synthesis by stereoselective, methylene-free enyne cross metathesis.
PubMed:Ozonolysis of 1,4-cyclohexadienes in the presence of methanol and acid. Mechanism and intermediates in the conversion of 1,4-cyclohexadiene derivatives to beta-keto esters.
PubMed:alpha,5-didehydro-3-picoline diradicals from skipped azaenediynes: computational and trapping studies of an aza-Myers-Saito cyclization.
PubMed:Reaction of tetramethylpiperidine N-oxides with persistent triplet diphenylcarbenes.
PubMed:Aquasonolysis of selected cyclic C(6)H(x) hydrocarbons.
PubMed:Insertion of alkynes into the Pt-Si bond of silylplatinum complexes leading to the formation of 4-sila-3-platinacyclobutenes and 5-sila-2-platina-1,4-cyclohexadienes.
PubMed:Palladium-catalyzed equilibrium addition of acidic OH groups across dienes.
PubMed:Synthesis and cycloaromatization of a cyclic enyne-allene prodrug.
PubMed:Monomeric MnIII/II and FeIII/II complexes with terminal hydroxo and oxo ligands: probing reactivity via O-H bond dissociation energies.
PubMed:A mechanistic dichotomy in ruthenium-catalyzed propargyl alcohol reactivity: a novel hydrative diyne cyclization.
PubMed:Ambient temperature activation of haloporphyrinic-enediynes: electronic contributions to bergman cycloaromatization.
PubMed:A novel and short synthesis of (1,4/2)-cyclohex-5-ene-triol and its conversion to (+/-)-proto-quercitol.
PubMed:Octahedral Ru(II) amido complexes TpRu(L)(L')(NHR) (Tp = hydridotris(pyrazolyl)borate; L = L' = P(OMe)3 or PMe3 or L = CO and L' = PPh3; R = H, Ph, or tBu): synthesis, characterization, and reactions with weakly acidic C-H bonds.
PubMed:Photochemistry of diethynyl sulfides: a cycloaromatization for the formation of five-membered rings.
PubMed:Synthesis of functionalized 1,4-cyclohexadienes through intramolecular anionic dearomatization of N-alkyl-N-benzyldiphenylphosphinamides. Insight into the reaction mechanism.
PubMed:Inversion of 4-methoxybenzophenone triplet in aqueous solutions.
PubMed:Fluorescent quenching of the 2-naphthoxide anion by aliphatic and aromatic halides. Mechanism and consequences of electron transfer reactions.
PubMed:Synthesis of the 5-7-6 core of guanacastepenes. Construction of C8 quaternary carbon via the inversion of stereochemistry.
PubMed:1,2-dithiin annelated with bicyclo[2.2.2]octene frameworks. One-electron and two-electron oxidations and formation of a novel 2,3,5,6-tetrathiabicyclo[2.2.2]oct-7-ene radical cation with remarkable stability owing to a strong transannular interaction.
PubMed:Cyclohexadiene-trans-diols as versatile starting material in natural product synthesis: short and efficient synthesis of iso-crotepoxide and ent-senepoxide.
PubMed:Regio- and diastereoselective preparation of tetrahydrobenzo[c]-1-aza-2lambda(5)-phospholes through dearomatization cyclization of lithiated N-benzyl-N-alkyl(diphenyl)phosphinamides. Synthesis of gamma-(N-alkylamino)phosphinic acids.
PubMed:Oxidations of hydrocarbons by manganese(III) tris(hexafluoroacetylacetonate).
PubMed:Evidence for facile atropisomerism and simple (non-nucleophilic) biradical-forming cycloaromatization within kedarcidin chromophore aglycon.
PubMed:Spin surface crossing in chromium-mediated olefin epoxidation with O(2).
PubMed:Synthesis of a novel, highly symmetric bis-oxa-bridged compound.
PubMed:Regiochemistry of the photostimulated reaction of the phthalimide anion with 1-iodoadamantane and tert-butylmercury chloride by the S(RN)1 mechanism.
PubMed:A highly enantioselective intramolecular Heck reaction with a monodentate ligand.
PubMed:C-H bond activation by a ferric methoxide complex: modeling the rate-determining step in the mechanism of lipoxygenase.
PubMed:Preparation of the octahedral d(6) amido complex TpRu(CO)(PPh(3))(NHPh) (Tp = Hydridotris(pyrazolyl)borate): solid-state structural characterization and reactivity.
PubMed:Formation, characterization, and reactivity of bis(mu-oxo)dinickel(III) complexes supported by a series of bis[2-(2-pyridyl)ethyl]amine ligands.
PubMed:Desaturation reactions catalyzed by soluble methane monooxygenase.
PubMed:Thermolysis of Benzoenyne-Allenes To Form Biradicals and Subsequent Intramolecular Trapping with a Tetraarylallene To Generate Two Triarylmethyl Radical Centers.
PubMed:Photoreduction of Azoalkanes by Direct Hydrogen Abstraction from 1,4-Cyclohexadiene, Alcohols, Stannanes, and Silanes.
PubMed:Generation and reactivity of the 4-aminophenyl cation by photolysis of 4-chloroaniline.
PubMed:Product studies and laser flash photolysis on alkyl radicals containing two different beta-leaving groups are consonant with the formation of an olefin cation radical.
PubMed:Diels-Alder reaction of 1,3-butadiene derivatives with 1-methyl-2(1H)-quinolones having an electron-withdrawing group at the 4-position.
PubMed:Mechanism of lipid peroxidation photosensitized by tiaprofenic acid: product studies using linoleic acid and 1,4-cyclohexadienes as model substrates.
PubMed:A nonheme iron(II) complex that models the redox cycle of lipoxygenase.
PubMed:A solvolytic C-C cleavage reaction of 6-acetoxycyclohexa-2,4-dienones: mechanistic implications for the intradiol catechol dioxygenases.
PubMed:A molecular logic gate.
PubMed:cis,cis,cis-tetramethyl 1,2,4,5-cyclohexanetetracarboxylate
PubMed:Reductions with lithium in low molecular weight amines and ethylenediamine
PubMed:2,3-Dioxabicyclo
PubMed:Iodophosphoryloxylation of carbon-carbon multibonds and its application to glycals
PubMed:Diels-alder adducts of 5-alkynylcyclopentadienols with tetracyanoethylene and dimethyl acetylenedicarboxylate: An X-ray crystallographic study of unexpected rearrangement products
PubMed:Hydrogen atom abstraction by Cu(II)- and Zn(II)-phenoxyl radical complexes, models for the active form of galactose oxidase.
PubMed:Mode of substrate interaction and energetics of carbon-oxygen bond formation of the dopamine beta-monooxygenase reaction.
PubMed:Two different types of dehalogenases, LinA and LinB, involved in gamma-hexachlorocyclohexane degradation in Sphingomonas paucimobilis UT26 are localized in the periplasmic space without molecular processing.
PubMed:Novel hydrophilic cyclic monomers in hydrogel synthesis.
PubMed:Purification and characterization of a haloalkane dehalogenase of a new substrate class from a gamma-hexachlorocyclohexane-degrading bacterium, Sphingomonas paucimobilis UT26.
PubMed:A Concise and Convenient Synthesis of DL-proto-Quercitol and DL-gala-Quercitol via Ene Reaction of Singlet Oxygen Combined with [2 + 4] Cycloaddition to Cyclohexadiene.
PubMed:Reactions of Alkynyldihaloboranes with 1,3-Dienes. 1,4-Alkynylborations and Stepwise Diels-Alder Reactions.
PubMed:Acceleration of a Diels-Alder reaction by a self-assembled molecular capsule.
PubMed:Stereoselective Epoxidation of Cyclohexa-Anellated Triquinacenes with Iodine/Silver(I) Oxide As Compared to m-Chloroperbenzoic Acid(1).
PubMed:Influence of combined AC-DC magnetic fields on free radicals in organized and biological systems. Development of a model and application of the radical pair mechanism to radicals in micelles.
PubMed:Iron(II)/reductant(DH2)-induced activation of dioxygen for the hydroxylation and ketonization of hydrocarbons; mimics for the cytochrome P-450 hydroxylase/reductase system.
PubMed:The oxidation of tetrasubstituted alkenes by cytochrome P450.
PubMed:Determination of ion frequencies in a quadrupole ion trap by using a fast direct current pulse as pump and a laser probe.
PubMed:Application of the radical pair mechanism to free radicals in organized systems: can the effects of 60 Hz be predicted from studies under static fields?
PubMed:Cloning and sequencing of a dehalogenase gene encoding an enzyme with hydrolase activity involved in the degradation of gamma-hexachlorocyclohexane in Pseudomonas paucimobilis.
PubMed:Increased NAD(P)H:(quinone-acceptor)oxidoreductase activity is associated with density-dependent growth inhibition of normal but not transformed cells.
PubMed:Effect of alpha-tocopherol on the volatile thermal decomposition products of methyl linoleate hydroperoxides.
PubMed:Role of Ethylene Metabolism in Amaranthus retroflexus.
PubMed:A phase II clinical trial of diaziquone in the treatment of patients with recurrent endometrial carcinoma. A Gynecologic Oncology Group study.
PubMed:Ab initio molecular electrostatic potentials of perillartine analogues: implications for sweet-taste receptor recognition.
PubMed:Reactivity of perhydroxyl (HOO.) with 1,4-cyclohexadiene (model for allylic groups in biomembranes).
PubMed:Tris(picolinato)manganese(II): a chemical model for the mechanism and function of mitochondrial superoxide dismutase.
PubMed:Reactivity and activation of dioxygen-derived species in aprotic media (a model matrix for biomembranes).
PubMed:Effect of AZQ (1,4-cyclohexadiene-1,4-diacarbamic acid-2,5-bis(1-aziridinyl)-3,6 -dioxodiethylester) in recurring supratentorial malignant brain gliomas--a Phase II study. EORTC Brain Tumour Cooperative Group.
PubMed:Base (O.-2, e-, or OH-)-induced autoxygenation of organic substrates: a model chemical system for cytochrome P-450-catalyzed monoxygenation and dehydrogenation by dioxygen.
PubMed:In vitro versus in vivo correlations of chemosensitivity of human medulloblastoma.
PubMed:Activation and inactivation of cancer chemotherapeutic agents by rat hepatocytes cocultured with human tumor cell lines.
PubMed:Chemotherapy and radiation therapy of human medulloblastoma in athymic nude mice.
PubMed:Survival and cell cycle kinetics responses of Chinese hamster ovary cells, and clones of human adenocarcinoma of the stomach and astrocytoma to diaziquone (AZQ) in vitro.
PubMed:Phase II clinical evaluation of AZQ in colorectal cancer.
PubMed:L-1,4-cyclohexadiene-1-alanine, an antimetabolite of l-phenylalanine produced by a Pseudomonas.
PubMed:Combined modality treatment using radiation and/or chemotherapy in an athymic nude mouse-human medulloblastoma and glioblastoma xenograft model.
PubMed:Potential CNS antitumor agents VI: aziridinylbenzoquinones III.
PubMed:Potential new artificial sweetener from study of structure-taste relationships.
PubMed:Letter: The effect of crystal packing and defects on desolvation of hydrate crystals of caffeine and L-(--)-1,4-cyclohexadiene-1-alanine.
PubMed:Use of L-1,4-cyclohexadiene-1-alanine in peptide synthesis as a phenylalanine analog.
PubMed:The solid-state dehydrogenation of L-1,4-cyclohexadiene-1-alanine hydrate to L-phenylalanine.
PubMed:L-1,4-cyclohexadiene-1-alanine, an antagonist of phenylalanine from Streptomyces.
PubMed:1,4-cyclohexadiene-1-alanine (2,5-dihydrophenylalanine) a new inhibitor of phenylalanine for the rat and Leuconostoc dextranicum 8086.
 
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