EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dimethyl imidazolidinone
karbomos TsEM

Supplier Sponsors

CAS Number: 80-73-9Picture of molecule3D/inchi
Other(deleted CASRN):95263-95-9
ECHA EINECS - REACH Pre-Reg:201-304-8
FDA UNII: 5C1YQQ9M90
Nikkaji Web:J11.846J
Beilstein Number:0108808
MDL:MFCD00003188
XlogP3-AA:-0.50 (est)
Molecular Weight:114.14790000
Formula:C5 H10 N2 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:humectants, skin conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.04400 @ 25.00 °C.
Refractive Index:1.47200 @ 20.00 °C.
Melting Point: 8.20 °C. @ 760.00 mm Hg
Boiling Point: 221.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.100000 mmHg @ 25.00 °C. (est)
Flash Point: 176.00 °F. TCC ( 80.00 °C. )
logP (o/w): -0.030 (est)
Soluble in:
 water, 9554 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: hair conditioning
humectants
skin conditioning
 
Suppliers:
Glentham Life Sciences
1,3-Dimethyl-2-imidazolidinone
Santa Cruz Biotechnology
For experimental / research use only.
1,3-Dimethyl-2-imidazolidinone
Sigma-Aldrich: Aldrich
For experimental / research use only.
1,3-Dimethyl-2-imidazolidinone ≥99.0% (GC)
TCI AMERICA
For experimental / research use only.
1,3-Dimethyl-2-imidazolidinone >99.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 2840 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Medicinal Chemistry. Vol. 11, Pg. 214, 1968.

oral-rat LD50 1190 uL/kg
SKIN AND APPENDAGES (SKIN): HAIR: OTHER BEHAVIORAL: TREMOR SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 191, 1992.

Dermal Toxicity:
skin-rabbit LD50 930 uL/kg
GASTROINTESTINAL: OTHER CHANGES GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS BEHAVIORAL: TREMOR
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 191, 1992.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
humectants, skin conditioning
Recommendation for dimethyl imidazolidinone usage levels up to:
 not for fragrance use.
 
Recommendation for dimethyl imidazolidinone flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):80-73-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :6661
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
1,3-dimethylimidazolidin-2-one
Chemidplus:0000080739
RTECS:NJ0660000 for cas# 80-73-9
 
References:
 1,3-dimethylimidazolidin-2-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):6661
Pubchem (sid):134972330
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2933.29.9000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
1,3-dimethyl-2-imidazolidinone
1,3-dimethylethyleneurea
N,N'-dimethylethyleneurea
1,3-dimethylimidazolidin-2-one
N,N'-dimethylimidazolidinone
N,N'-dimethylimidazolidone
 karbomos TsEM
 rhonite 1
 

Articles:

PubMed:Full evaporation headspace gas chromatography for sensitive determination of high boiling point volatile organic compounds in low boiling matrices.
PubMed:Synthesis of 1,2-bis(trimethylsilyl)benzene derivatives from 1,2-dichlorobenzenes using a hybrid metal Mg/CuCl in the presence of LiCl in 1,3-dimethyl-2-imidazolidinone.
PubMed:Poly[bis-(1,3-dimethyl-imidazolidin-2-one)(μ2-2,5-dioxidoterephthalato)zirconium(IV)].
PubMed:L-Leucylglycine 0.67-hydrate and [(4S)-2,2-dimethyl-4-(2-methylpropyl)-5-oxoimidazolidin-3-ium-1-yl]acetate.
PubMed:Density functional theory study on the reaction mechanism of synthesizing 1,3-dimethyl-2-imidazolidinone by urea method.
PubMed:3-{[(4Z)-1,2-Dimethyl-5-oxoimidazol-4-yl-idene]meth-yl}-4-hy-droxy-benzonitrile.
PubMed:Zinc-mediated highly α-regioselective prenylation of imines with prenyl bromide.
PubMed:Inorganic-organic hybrid materials through post-synthesis modification: Impact of the treatment with azides on the mesopore structure.
PubMed:Light-scattering analysis of native wood holocelluloses totally dissolved in LiCl-DMI solutions: high probability of branched structures in inherent cellulose.
PubMed:Identification of a higher-order organozincate intermediate involved in Negishi cross-coupling reactions by mass spectrometry and NMR spectroscopy.
PubMed:Coefficients of evaporation and gas phase diffusion of low-volatility organic solvents in nitrogen from interferometric study of evaporating droplets.
PubMed:In situ diffuse reflectance infrared Fourier transform spectroscopy of MCM-41 mesoporous silica: mechanistic consideration on the chemical fixation of CO2 with N,N'-dimethylethylenediamine to 1,3-dimethyl-2-imidazolidinone.
PubMed:Amphiphilic paramagnetic neutral gold dithiolene complexes.
PubMed:Mesoporous silica-catalysed continuous chemical fixation of CO(2) with N,N'-dimethylethylenediamine in supercritical CO(2): the efficient synthesis of 1,3-dimethyl-2-imidazolidinone.
PubMed:(2R,5S)-5-Benzyl-2,3-dimethyl-4-oxo-2-phenyl-imidazolidin-1-ium chloride.
PubMed:Pentakis(trifluoromethyl)phenyl, a sterically crowded and electron-withdrawing group: synthesis and acidity of pentakis(trifluoromethyl)benzene, -toluene, -phenol, and -aniline.
PubMed:SEC-MALS-QELS study on the molecular conformation of cellulose in LiCl/amide solutions.
PubMed:Matrix media selection for the determination of residual solvents in pharmaceuticals by static headspace gas chromatography.
PubMed:Rheological properties and molecular structure of tunicate cellulose in LiCl/1,3-dimethyl-2-imidazolidinone.
PubMed:2,2,3-Trisubstituted Tetrahydrofurans and 2H-Tetrahydropyrans by Tandem Demethoxycarbonylation-Michael Addition Reactions.
PubMed:1,5-Dimethyl-4-phenylimidazolidin-2-one-derived iminic glycinimides: useful new reagents for practical asymmetric synthesis of alpha-amino acids.
PubMed:Synthesis and Physical Properties of Sterically Congested Cycloalkenes, 1,2-Di-tert-butyl-3,3,5,5-tetramethylcyclopentene and 1,2-Di-tert-butyl-3,3,6,6-tetramethylcyclohexene.
PubMed:Improved and efficient synthesis of 1alpha-hydroxy-[6-(2)H] and 1alpha-hydroxy-[6,19,19-(2)H]vitamin D3 derivatives.
PubMed:Reduced proconvulsant activity of caffeine in rats after a series of electroconvulsive seizures.
PubMed:Beta-adrenergic regulation of the eosinophil respiratory burst as detected by lucigenin-dependent luminescence.
PubMed:Selective, centrally acting serotonin 5-HT2 antagonists. 2. Substituted 3-(4-fluorophenyl)-1H-indoles.
PubMed:K(+)-evoked depolarization stimulates cyclic AMP accumulation in photoreceptor-enriched retinal cell cultures: role of calcium influx through dihydropyridine-sensitive calcium channels.
PubMed:Effect of organic N-halamines on selected membrane functions in intact Staphylococcus aureus cells.
PubMed:Replacement of carcinogenic solvent HMPA by DMI in insect sex pheromone synthesis.
PubMed:Combined halogen disinfectants in poultry processing.
PubMed:Potential uses of combined halogen disinfectants in poultry processing.
PubMed:The effects of 16,16-dimethyl PGE2 and phosphodiesterase inhibitors on Con A blastogenic responses and NK cytotoxic activity of mouse spleen cells.
PubMed:Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H2-receptors.
PubMed:Zetidoline metabolism by rat liver microsomes. Formation of metabolites with potential neuroleptic activity.
PubMed:Specificity in enzyme inhibition. 3. Synthesis of 5-substituted 2,2-dimethyl-4-imidazolidinones as inhibitors of tyrosine decarboxylase and histidine decarboxylase.
PubMed:Drug-induced alterations in morphology and level of cAMP in cultured human glioma cells.
PubMed:Correlation between the carcinogenicities of nitrofuran derivatives and their destructive actions on sebaceous glands of mouse skin.
PubMed:[Pharmaceutical studies of imidazolidinone derivatives. V. Stability of 1,2-dimethyl-3-phenyl-4-imidazolidinone and 3-phenyl-4-imidazolidinone in blood].
PubMed:[Pharmaceutical studies of imidazolidinone derivatives. I. Stability of 1,2-dimethyl-3-phenyl-4-imidazolidinone].
 
Notes:
None found
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