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trimellitic acid
1,2,4-benzenetricarboxylic acid

Supplier Sponsors

Name:benzene-1,2,4-tricarboxylic acid
CAS Number: 528-44-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:208-432-3
FDA UNII: 7NVY29MQ5F
Nikkaji Web:J6.674E
Beilstein Number:2214815
MDL:MFCD00002470
XlogP3:0.30 (est)
Molecular Weight:210.14202000
Formula:C9 H6 O6
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:monomer in epoxy resins for coatings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
DG SANTE Food Contact Materials:trimellitic acid
FDA Mainterm (IAUFC):528-44-9 ; TRIMELLITIC ACID
 
Physical Properties:
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 219.00 °C. @ 760.00 mm Hg
Boiling Point: 505.51 °C. @ 760.00 mm Hg (est)
Flash Point: 525.00 °F. TCC ( 273.60 °C. ) (est)
logP (o/w): 1.240 (est)
Soluble in:
 water, 21000 mg/L @ 25 °C (exp)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
1,2,4-Benzenetricarboxylic acid 95%
EMD Millipore
For experimental / research use only.
1,2,4-Benzenetricarboxylic acid
Santa Cruz Biotechnology
For experimental / research use only.
1,2,4-Benzenetricarboxylic acid
Sigma-Aldrich: Aldrich
For experimental / research use only.
1,2,4-Benzenetricarboxylic acid ≥99%
TCI AMERICA
For experimental / research use only.
Trimellitic Acid >98.0%(HPLC)(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 2500 mg/kg
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(7), Pg. 57, 1974.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
monomer in epoxy resins for coatings
Recommendation for trimellitic acid usage levels up to:
 not for fragrance use.
 
Recommendation for trimellitic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on Food Additives a 4th list of substances for food contact materials
View page or View pdf

Report of ESCO WG on non-plastic Food Contact Materials
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):528-44-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :10708
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
benzene-1,2,4-tricarboxylic acid
Chemidplus:0000528449
RTECS:DC1980000 for cas# 528-44-9
 
References:
 benzene-1,2,4-tricarboxylic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):10708
Pubchem (sid):134978797
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2917.39.7000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
1,2,4-benzene tricarboxylic acid
 benzene-1,2,4-tricarboxylic acid
1,2,4-benzenetricarboxylic acid
1,2,4-benzenetricarboxylicacid
 

Articles:

PubMed:Semiconductor Behavior of a Three-Dimensional Strontium-Based Metal-Organic Framework.
PubMed:Separation of the isomers of benzene poly(carboxylic acid)s by quaternary ammonium salt via formation of deep eutectic solvents.
PubMed:Biotechnological production of muconic acid: current status and future prospects.
PubMed:Role of 2-hydroxyethyl methacrylate in the interaction of dental monomers with collagen studied by saturation transfer difference NMR.
PubMed:Bismuth tri- and tetraarylcarboxylates: crystal structures, in situ X-ray diffraction, intermediates and luminescence.
PubMed:Assembly and properties of transition-metal coordination polymers based on semi-rigid bis-pyridyl-bis-amide ligand: effect of polycarboxylates on the dimensionality.
PubMed:Chronic administration of the selective P2X3, P2X2/3 receptor antagonist, A-317491, transiently attenuates cancer-induced bone pain in mice.
PubMed:Simultaneous analysis of acidulants and preservatives in food samples by using capillary zone electrophoresis with indirect UV detection.
PubMed:P2 receptor antagonists prevent synaptic failure and extracellular signal-regulated kinase 1/2 activation induced by oxygen and glucose deprivation in rat CA1 hippocampus in vitro.
PubMed:CoMn2O4 spinel from a MOF: synthesis, structure and magnetic studies.
PubMed:Effect of self-adhesive resin cement and tribochemical treatment on bond strength to zirconia.
PubMed:Perfluorosulfonic acid membrane catalysts for optical sensing of anhydrides in the gas phase.
PubMed:Design of a new dental adhesive--effect of a water-soluble sodium acylphosphine oxide with crown ether on adhesion to dental hard tissues.
PubMed:Determining organic impurities in mother liquors from oxidative terephthalic acid synthesis by microemulsion electrokinetic chromatography.
PubMed:Sample stacking for determination of aromatic acid impurities by microemulsion electrokinetic chromatography.
PubMed:Complexation and determination of palladium (II) ion with para-Cl-phenylazo-R-acid spectrophotometrically.
PubMed:Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naive THp-1 cells.
PubMed:Determination of common inorganic anions and cations by non-suppressed ion chromatography with column switching.
PubMed:Effect of solvent type on the degradation of 4-MET.
PubMed:CCR4 and CCR10 ligands play additive roles in mouse contact hypersensitivity.
PubMed:Activation of urothelial transient receptor potential vanilloid 4 by 4alpha-phorbol 12,13-didecanoate contributes to altered bladder reflexes in the rat.
PubMed:Analysis of chemical interaction of 4-MET with hydroxyapatite using XPS.
PubMed:Biocompatibility and drug release behavior of spontaneously formed phospholipid polymer hydrogels.
PubMed:Asymmetry induction by cooperative intermolecular hydrogen bonds in surface-anchored layers of achiral molecules.
PubMed:Critical design features of phenyl carboxylate-containing polymer microbicides.
PubMed:Simultaneous determination of inorganic anions and organic acids in amine solutions for sour gas treatment by capillary electrophoresis with indirect UV detection.
PubMed:Design of extended surface-supported chiral metal-organic arrays comprising mononuclear iron centers.
PubMed:Spontaneously forming hydrogel from water-soluble random- and block-type phospholipid polymers.
PubMed:A-317491, a selective P2X3/P2X2/3 receptor antagonist, reverses inflammatory mechanical hyperalgesia through action at peripheral receptors in rats.
PubMed:Effects of carboxyl groups on the adsorption behavior of low-molecular-weight substances on a stainless steel surface.
PubMed:Migration of trimellitic acid from epoxy anhydride can coatings into foods.
PubMed:Comparative study on adhesive performance of functional monomers.
PubMed:Synthesis and antimicrobial activity of new adamantane derivatives III.
PubMed:Application of capillary electrophoresis for organic acid analysis in herbal studies.
PubMed:Conformational and quantum analysis of dental adhesive carboxylic acid and carboxylic acid anhydride monomers.
PubMed:Analysis of low molecular weight organic acids in water with capillary zone electrophoresis employing indirect photometric detection.
PubMed:Photoinduced electron-transfer reactions with quinolinic and trimellitic acid imides: experiments and spin density calculations(1)
PubMed:Development of cellulose derivatives as novel enteric coating agents soluble at pH 3.5-4.5 and higher.
PubMed:Acute autoimmune response in a case of pyromellitic acid dianhydride-induced hemorrhagic alveolitis.
PubMed:[Dosimetry using pyromellitic acid and trimellitic acid. Part 1].
PubMed:Laser-Raman spectroscopic study of the adhesive interface; analysis between 4-META/MMA-TBB resin and bovine or human dentin.
PubMed:Laser-Raman Spectroscopic study of the adhesive interface between 4-MET/MMA-TBB resin and hydroxyapatite or bovine enamel.
PubMed:Construction, characteristics and application of a benzene-1,2,4-tricarboxylic acid selective electrode.
PubMed:Specificity of the human IgE response to inhaled acid anhydrides.
PubMed:Simultaneous determination of trimellitic anhydride and its trimellitic acid impurity by GC/FID.
PubMed:Human antibodies against trimellityl proteins: comparison of specificities of IgG, IgA and IgE classes.
PubMed:Asthma due to inhaled chemical agents--epoxy resin systems containing phthalic acid anhydride, trimellitic acid anhydride and triethylene tetramine.
PubMed:Hydrolysis study of organic acid anhydrides by differential thermal analysis--II. Maleic anhydride and trimellitic anhydride.
 
Notes:
None found
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