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1,2,3,4-tetrahydronaphthalene
naphthalene, 1,2,3,4-tetrahydro-

Supplier Sponsors

Name:1,2,3,4-tetrahydronaphthalene
CAS Number: 119-64-2Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:204-340-2
FDA UNII: FT6XMI58YQ
Nikkaji Web:J2.002H
Beilstein Number:1446407
MDL:MFCD00001733
XlogP3:3.50 (est)
Molecular Weight:132.20564000
Formula:C10 H12
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.97300 @ 25.00 °C.
Boiling Point: 207.60 °C. @ 760.00 mm Hg
Vapor Pressure:0.281000 mmHg @ 25.00 °C. (est)
Flash Point: 171.00 °F. TCC ( 77.22 °C. )
logP (o/w): 3.490
Soluble in:
 water, 94.26 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Tetralin
EMD Millipore
For experimental / research use only.
1,2,3,4-Tetrahydronaphthalene
Penta International
1,2,3,4-TETRAHYDRONAPHTHALENE
Santa Cruz Biotechnology
For experimental / research use only.
1,2,3,4-Tetrahydronaphthalene
Sigma-Aldrich
For experimental / research use only.
1,2,3,4-Tetrahydronaphthalene anhydrous, 99%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 1620 uL/kg
Union Carbide Data Sheet. Vol. 1/12/1972

Dermal Toxicity:
skin-rabbit LD50 17300 uL/kg
Union Carbide Data Sheet. Vol. 1/12/1972

Inhalation Toxicity:
inhalation-guinea pig LC50 275 ppm
"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 47, 1986.

 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for 1,2,3,4-tetrahydronaphthalene usage levels up to:
 not for fragrance use.
 
Recommendation for 1,2,3,4-tetrahydronaphthalene flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):119-64-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :8404
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
1,2,3,4-tetrahydronaphthalene
Chemidplus:0000119642
EPA/NOAA CAMEO:hazardous materials
RTECS:119-64-2
 
References:
 1,2,3,4-tetrahydronaphthalene
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:119-64-2
Pubchem (cid):8404
Pubchem (sid):134974555
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Metabolomics Database:Search
UM BBD:Search
KEGG (GenomeNet):C14114
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2902.90.9000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•"essence of tetralin" is commercial mixture of tetralin & hexalin, pale yellow liquid which is better solvent of resins than tetralin alone . •grades or purity: 90+% •the commercial product typically has a tetrahydronapthalene content of >97 wt%. •grade: technical
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 coffee
Search PMC Picture
 
Synonyms:
 benzocyclohexane
 d(sup 5,7,9)-naphthantriene
 naphthalene 1,2,3,4-tetrahydride
 naphthalene, 1,2,3,4-tetrahydro-
 tetralene
 tetralin
 

Articles:

PubMed:Alkaline pretreatment and the synergic effect of water and tetralin enhances the liquefaction efficiency of bagasse.
PubMed:The effects of serotonin1A receptor on female mice body weight and food intake are associated with the differential expression of hypothalamic neuropeptides and the GABAA receptor.
PubMed:Dopamine D3 receptors in the basolateral amygdala and the lateral habenula modulate cue-induced reinstatement of nicotine seeking.
PubMed:A well-refined in vitro model derived from human embryonic stem cell for screening phytochemicals with midbrain dopaminergic differentiation-boosting potential for improving Parkinson's disease.
PubMed:Activation of prelimbic 5-HT1A receptors produces antidepressant-like effects in a unilateral rat model of Parkinson's disease.
PubMed:Simultaneous detection and quantification of select nitromusks, antimicrobial agent, and antihistamine in fish of grocery stores by gas chromatography-mass spectrometry.
PubMed:Comprehensive monitoring of synthetic musk compounds from freshwater to coastal environments in Korea: with consideration of ecological concerns and bioaccumulation.
PubMed:The effect of serotonergic system on nociceptin/orphanin FQ induced food intake in chicken.
PubMed:Systemic administration of 8-OH-DPAT and eticlopride, but not SCH23390, alters loss-chasing behavior in the rat.
PubMed:Comparison of the conditioned reinforcing properties of a safety signal and appetitive stimulus: effects of d-amphetamine and anxiolytics.
PubMed:Electrophysiological and pharmacological properties of GABAergic cells in the dorsal raphe nucleus.
PubMed:Microarray analysis of gene expression in mouse (strain 129) embryonic stem cells after typical synthetic musk exposure.
PubMed:[Effect of the selective ligands 5-HT(1A) receptors administration on the impulsive and self-control behavior in rats].
PubMed:Serotonergic control of ingestive and post-ingestive behaviors in pigeons (Columba livia): the role of 5-HT1A receptor-mediated central mechanisms.
PubMed:Effect of ambient temperature on the thermoregulatory and locomotor stimulant effects of 4-methylmethcathinone in Wistar and Sprague-Dawley rats.
PubMed:Activation of dorsal raphe serotonin neurons is necessary for waiting for delayed rewards.
PubMed:Tissue concentrations, bioaccumulation, and biomagnification of synthetic musks in freshwater fish from Taihu Lake, China.
PubMed:Uptake of galaxolide, tonalide, and triclosan by carrot, barley, and meadow fescue plants.
PubMed:The role of central 5-HT(2C) and NMDA receptors on LPS-induced feeding behavior in chickens.
PubMed:Lignans from the root of Rhodiola crenulata.
PubMed:The occurrence of synthetic musks in human breast milk in Sichuan, China.
PubMed:Dopamine as an anorectic neuromodulator in the cockroach Rhyparobia maderae.
PubMed:A modified adjusting delay task to assess impulsive choice between isocaloric reinforcers in non-deprived male rats: effects of 5-HT₂A/C and 5-HT₁A receptor agonists.
PubMed:Eating high fat chow increases the sensitivity of rats to 8-OH-DPAT-induced lower lip retraction.
PubMed:Effects of fenfluramine, 8-OH-DPAT, and tryptophan-enriched diet on the high-ethanol intake by rats bred for susceptibility to stress.
PubMed:Effects of the polycyclic ketone tonalide (AHTN) on some cell viability parameters and transcription of P450 and immunoregulatory genes in rainbow trout RTG-2 cells.
PubMed:Fluoxetine prevents 8-OH-DPAT-induced hyperphagia in Fischer inbred rats.
PubMed:Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists.
PubMed:Effects of serotonin (5-HT)1A and 5-HT2A receptor agonists on schedule-controlled responding in rats: drug combination studies.
PubMed:Differential effects of serotonin 5-HT1A receptor agonists on the discriminative stimulus effects of the 5-HT2A receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rats and rhesus monkeys.
PubMed:Reduction of the number of new cells reaching olfactory bulbs impairs olfactory perception in the adult opossum.
PubMed:Attenuation of somatodendritic responses to 8-hydroxy-2-di-npropylamino tetralin following long-term dietary sugar consumption in rats.
PubMed:Behavioural and electroencephalographic effects of systemic injections of 8-OH-DPAT in the pigeon (Columba livia).
PubMed:Food restriction and streptozotocin differentially modify sensitivity to the hypothermic effects of direct- and indirect-acting serotonin receptor agonists in rats.
PubMed:WAY 100635 produces discriminative stimulus effects in rats mediated by dopamine D(4) receptor activation.
PubMed:Decline in serotonergic firing activity and desensitization of 5-HT1A autoreceptors after chronic unpredictable stress.
PubMed:Serotonin 5-HT(2) and 5-HT(1A)-like receptors differentially modulate aggressive behaviors in Drosophila melanogaster.
PubMed:Hypophagic and dipsogenic effect of the 5-HT1A receptor agonist 8-OH-DPAT in broiler chickens.
PubMed:Desensitization of pre and post synaptic 5-HT-1A receptor responses following long term consumption of sugar rich diet: implications for sugar-induced obesity.
PubMed:Exaggerated feedback control decreases brain serotonin concentration and elicits hyperactivity in a rat model of diet-restriction-induced anorexia nervosa.
PubMed:The effects of metergoline and 8-OH-DPAT injections into arcuate nucleus and lateral hypothalamic area on feeding in female rats during the estrous cycle.
PubMed:Effect of (-)-trans-PAT, a novel 5-HT2C receptor agonist, on intake of palatable food in mice.
PubMed:Food restriction and streptozotocin treatment decrease 5-HT1A and 5-HT2A receptor-mediated behavioral effects in rats.
PubMed:The role of prior stressor controllability and the dorsal raphé nucleus in sucrose preference and social exploration.
PubMed:Investigating the motivational mechanism of altered saline consumption following 5-HT(1A) manipulation.
PubMed:Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior.
PubMed:8-OH-DPAT inhibits both prandial and waterspray-induced grooming.
PubMed:8-Hydroxy-2-(di-n-propylamino)-tetralin inhibits food intake in fasted rats by an action at 5-HT1A receptors.
PubMed:Neurochemical and behavioral effects of 8-OH-DPAT following exposure to restraint stress in rats.
PubMed:Bioaccumulation, temporal trend, and geographical distribution of synthetic musks in the marine environment.
PubMed:Role of serotonin-1A receptors in restraint-induced behavioral deficits and adaptation to repeated restraint stress in rats.
PubMed:The effects of 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH-DPAT) on food intake in non-deprived C57BL6 mice.
PubMed:Effects of prenatal exposure to styrene trimers on genital organs and hormones in male rats.
PubMed:Discovery of tetralin ureas as potent melanin concentrating hormone 1 receptor antagonists.
PubMed:Effects of long term consumption of sugar as part of meal on serotonin 1-a receptor dependent responses.
PubMed:Treatment with 8-OH-DPAT attenuates the weight loss associated with activity-based anorexia in female rats.
PubMed:Influence of 5-HT1A agonist on the feeding behavior of Coturnix japonica (Galliformes: Aves).
PubMed:Prenatal ethanol exposure: sex differences in anxiety and anxiolytic response to a 5-HT1A agonist.
PubMed:Polycyclic musk compounds in higher trophic level aquatic organisms and humans from the United States.
PubMed:Effects of 5-HT1A and 5-HT2A receptor stimulation on temporal differentiation performance in the fixed-interval peak procedure.
PubMed:The 5-HT1A receptor and the stimulus effects of LSD in the rat.
PubMed:Occurrence of synthetic musk fragrances in marine mammals and sharks from Japanese coastal waters.
PubMed:Effects of the 5-HT(1A) agonist (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) on cocaine choice in cynomolgus monkeys.
PubMed:The influence of dehydroepiandrosterone and 8-OH-DPAT on the caloric intake and hypothalamic neurotransmitters of lean and obese Zucker rats.
PubMed:Evaluation of DOI, 8-OH-DPAT, eticlopride and amphetamine on impulsive responding in a reaction time task in rats.
PubMed:Behavioral effects of 8-OH-DPAT injections into pontine and mesencephalic areas containing 5-HT-immunoreactive perikarya in the pigeon.
PubMed:Complex discriminative stimulus properties of (+)lysergic acid diethylamide (LSD) in C57Bl/6J mice.
PubMed:Chronic mild stress induces behavioral and physiological changes, and may alter serotonin 1A receptor function, in male and cycling female rats.
PubMed:Differential effects of 8-OH-DPAT on two forms of appetitive pavlovian conditioning in the rat.
PubMed:Attenuation of nicotine's discriminative stimulus effects in rats and its locomotor activity effects in mice by serotonergic 5-HT2A/2C receptor agonists.
PubMed:Ingestive behaviors and metabolic fuels after central injections of 5-HT1A and 5-HT1D/1B receptors agonists in the pigeon.
PubMed:Y1 receptors regulate aggressive behavior by modulating serotonin pathways.
PubMed:Effect of 5-HT1A receptor activation on hypothalamic glucose.
PubMed:Short-term exposure to constant light promotes strong circadian phase-resetting responses to nonphotic stimuli in Syrian hamsters.
PubMed:Evaluation of the oral subchronic toxicity of AHTN (7-Acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthalene) in the rat.
PubMed:Chromogenic derivatives of AHTN (6-acetyl-1,1,2,4,4,7-hexamethyltetralin) react with amino acids and protein in vitro. Spectral characteristics of the colour products.
PubMed:Sex differences in the reversal of fluoxetine-induced anorexia following raphe injections of 8-OH-DPAT.
PubMed:Black cohosh acts as a mixed competitive ligand and partial agonist of the serotonin receptor.
PubMed:The effect of natural clinoptilolite on the serotonergic receptors in the brain of mice with mammary carcinoma.
PubMed:The differential effects of food restriction on 5-HT1A and 5-HT1B receptor mediated control of serotonergic transmission in the hippocampus and hypothalamus of rats.
PubMed:Effects of autoshaping procedures on 3H-8-OH-DPAT-labeled 5-HT1a binding and 125I-LSD-labeled 5-HT2a binding in rat brain.
PubMed:Effects of 8-OH-DPAT and WAY-100635 on performance on a time-constrained progressive-ratio schedule.
PubMed:Effects of triazolam, 8-OH-DPAT, and buspirone on repeated acquisition in squirrel monkeys.
PubMed:Antagonism by WAY-100635 of the effects of 8-OH-DPAT on performance on a free-operant timing schedule in intact and 5-HT-depleted rats.
PubMed:Serotonin and serotonin 1-A receptors in the failure of ethanol-treated rats to adapt to a repeated stress schedule.
PubMed:Role of 5-HT1A receptors in the control of food intake in obese Zucker rats of different ages.
PubMed:Effect of the 5-HT(1A) receptor agonist 8-OH-DPAT on food and water intake in chickens.
PubMed:Activation of 5-HT(1B) receptors in the nucleus accumbens reduces self-administration of amphetamine on a progressive ratio schedule.
PubMed:Investigations on possible serotonergic involvement in effects of OB-200G (polyherbal preparation) on food intake in female mice.
PubMed:Lesions of the posterior basolateral amygdala block feeding induced by systemic 8-OH-DPAT.
PubMed:The differential effects of intravenously administered 8-OH-DPAT on operant food intake in satiated and food-deprived pigs are mediated by central 5-HT(1A) receptors.
PubMed:A role for serotonin in lipopolysaccharide-induced anorexia in rats.
PubMed:Manipulation of operant responding for an ethanol-paired conditioned stimulus in the rat by pharmacological alteration of the serotonergic system.
PubMed:Posterodorsal amygdala lesions reduce feeding stimulated by 8-OH-DPAT.
PubMed:Behavioral effects Of 8-OH-DPAT in chronically stressed male and female rats.
PubMed:The 5-HT(1A) receptor agonist 8-OH-DPAT reduces rats' accuracy of attentional performance and enhances impulsive responding in a five-choice serial reaction time task: role of presynaptic 5-HT(1A) receptors.
PubMed:Effect of a serotonin 1-A agonist on food intake of Osborne-Mendel and S5B/P1 rats.
PubMed:Involvement of nitric oxide in the 5-HT1A autoreceptor-mediated hyperphagia in rats.
PubMed:Lack of evidence for a role of serotonin in interleukin-1-induced hypophagia.
PubMed:Feeding and 8-OH-DPAT-related release of serotonin in the rat lateral hypothalamus.
PubMed:The pharmacology of impulsive behaviour in rats VI: the effects of ethanol and selective serotonergic drugs on response choice with varying delays of reinforcement.
PubMed:Effects of various serotonin agonists, antagonists, and uptake inhibitors on the discriminative stimulus effects of methamphetamine in rats.
PubMed:Effects of the 5-HT1A receptor agonist 8-OH-DPAT on operant food intake in food-deprived pigs.
PubMed:A neuronal nitric oxide synthase inhibitor 7-nitroindazole reduces the 5-HT1A receptor against 8-OH-DPAT-elicited hyperphagia in rats.
PubMed:Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis.
PubMed:Antidepressant-like effects of 5-hydroxytryptamine1A receptor agonists on operant responding under a response duration differentiation schedule.
PubMed:Interaction of CCK and 8-OH-DPAT in the satiation of alcohol intake.
PubMed:Synergistic neurochemical and behavioral effects of fluoxetine and 5-HT1A receptor antagonists.
PubMed:Discriminative stimulus properties of the 5-HT1A receptor agonist BAY x 3702 in the rat.
PubMed:Reversal of fenfluramine and fluoxetine anorexia by 8-OH-DPAT is attenuated following raphe injection of 5,7-dihydroxytryptamine.
PubMed:Effects of adrenalectomy on hyperphagia induced by the 5-HT1A receptor agonist 8-OH-DPAT and 2-deoxy-D-glucose in rats.
PubMed:Dietary fat type influences protein consumption in rats given 8-hydroxy-2-(Di-n-propylamino)tetralin.
PubMed:Genotoxicity of polycyclic musk fragrances in the sister-chromatid exchange test.
PubMed:Differential effects of social stress on central serotonergic activity and emotional reactivity in Lewis and spontaneously hypertensive rats.
PubMed:Discriminative stimulus effects of 8-hydroxy-2-(di-n-propylamino)tetralin in pigeons and rats: species similarities and differences.
PubMed:Effects of 5-HT1A receptor ligands in a modified Geller-Seifter conflict model in the rat.
PubMed:Effects of food deprivation on midbrain 5-HT1A autoreceptors in Lewis and SHR rats.
PubMed:CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon.
PubMed:Role of CRH in the effects of 5-HT-receptor agonists on food intake and metabolic rate.
PubMed:Lack of interaction between devazepide and 8-OH-DPAT-induced hyperphagia in the rat.
PubMed:Evidence for a role for dopamine D3 receptors in the effects of dopamine agonists on operant behaviour in rats.
PubMed:Behavioural evidence that d-fenfluramine-induced anorexia in the rat is not mediated by the 5-HT1A receptor subtype.
PubMed:Selective effects of 8-OH-DPAT on social competition in the rat.
PubMed:Effect of the 5-HT1A agonist, 8-OH-DPAT on instrumental performance in rats.
PubMed:Behavioural effects in the rat of the putative dopamine D3 receptor agonist 7-OH-DPAT: comparison with quinpirole and apomorphine.
PubMed:The histaminergic, but not the serotoninergic, system mediates amylin's anorectic effect.
PubMed:Further selection of rat lines differing in 5-HT-1A receptor sensitivity: behavioral and functional correlates.
PubMed:Effects of systemic phenylpropanolamine and fenfluramine on serotonin activity within rat paraventricular hypothalamus.
PubMed:Discriminative stimulus effects of the 5HT1A agonist 8-OH-DPAT: attenuation by mu but not by kappa opioids.
PubMed:Multiple serotonin receptors: opportunities for new treatments for obesity?
PubMed:Effects of the 5-HT1A agonist 8-OH-DPAT on operant feeding in pigs.
PubMed:The effects of repeated treatment with 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) on the lever press responding of the rat under FI and DRL schedules of food reinforcement.
PubMed:Cholecystokinin attenuates incentive learning in rats.
PubMed:Distractibility and locomotor activity in rat following intra-collicular injection of a serotonin 1B-1D agonist.
PubMed:Alcohol drinking in rats injected ICV with 6-OHDA: effect of 8-OHDPAT and tropisetron (ICS 205930).
PubMed:Evidence for the involvement of the 5-HT1A receptor in CCK induced satiety in rats.
PubMed:Functional assessment of the 5-HT 1A-, 1B-, 2A/2C-, and 3-receptor subtypes on food intake and metabolic rate in rats.
PubMed:Mechanism of action of 8-OH-DPAT on learning and memory.
PubMed:Pretreatment with the 5-HT1A receptor agonists 8-OH-DPAT or gepirone does not attenuate the inhibitory effect of systemically administered cholecystokinin (CCK) on food intake in rats.
PubMed:Anticonflict and discriminative stimulus effects in the pigeon of a new methoxy-chroman 5-HT1A agonist, (+)S 20244 and its enantiomers (+)S 20499 and (-)S 20500.
PubMed:Effects of chlordiazepoxide, 8-OH-DPAT and ondansetron on radiation-induced decreases in food intake in rats.
PubMed:Effects of 8-OH-DPAT, 5-CT and muscimol on behaviour maintained by a DRL20 schedule of reinforcement, following microinjection into the dorsal or median raphe nuclei.
PubMed:Low doses of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)-tetralin (8-OH DPAT) increase ethanol intake.
PubMed:Indications of pre- and post-synaptic 5-HT1A receptor interactions in feeding behavior and neuroendocrine regulation.
PubMed:Administration of 8-OH-DPAT into the midbrain raphe nuclei: effects on medial hypothalamic NE-induced feeding.
PubMed:Effects of repeated 2-deoxy-D-glucose administration on ingestive, psychological, and 5-HT-related behaviours in the rat.
PubMed:Effects of 5-HT1A receptor ligands on a safety signal withdrawal procedure of conflict in the rat.
PubMed:8-OH-DPAT induces a selective increase in protein intake in ageing overweight animals.
PubMed:Sex difference in the feeding responses of non-deprived rats to the 5-HT1A agonists 8-OH-DPAT and gepirone.
PubMed:In vivo characterization of the putative 5-HT1A receptor antagonist SDZ 216,525 using two models of somatodendritic 5-HT1A receptor function.
PubMed:The effects of WAY-100135 and 8-hydroxy-2-(di-n-propylamino)tetralin on feeding in the rat.
PubMed:Modification of 8-OH-DPAT effects on learning by manipulation of the assay conditions.
PubMed:The 5-HT1A agonist 8-OH-DPAT increases attachment maintenance but decreases suckling-related intake in 17-18-day-old rat pups.
PubMed:Radiofrequency lesions of the PVN fail to modify the effects of serotonergic drugs on food intake.
PubMed:Attenuation of 8-OH-DPAT induced feeding after lesions of the area postrema/immediately adjacent nucleus of the solitary tract.
PubMed:Paraventricular nucleus injections of idazoxan block feeding induced by paraventricular nucleus norepinephrine but not intra-raphe 8-hydroxy-2-(di-n-propylamino)tetralin.
PubMed:Injecting 5-HT into the PVN does not prevent feeding induced by injecting 8-OH-DPAT into the raphe.
PubMed:The discriminative stimulus effects of cocaine in pigeons.
PubMed:Diurnal variations in the feeding response to 8-OH-DPAT injected into the dorsal or median raphe.
PubMed:Diurnal rhythms of 5-HT1A and 5-HT2 receptor binding in euthermic and torpor prone deermice, Peromyscus maniculatus.
PubMed:Evaluation of the reinforcing and discriminative stimulus effects of cocaine in combination with (+)-AJ76 or clozapine.
PubMed:Regional analysis of 5-HT1A receptors in two species of Peromyscus.
PubMed:A comparison of the effects of dorsal or median raphe injections of 8-OH-DPAT in three operant tasks measuring response inhibition.
PubMed:The hypophagic effect of restraint stress in rats can be mediated by 5-HT2 receptors in the paraventricular nucleus of the hypothalamus.
PubMed:Metabolism of tetralin (1,2,3,4-tetrahydronaphthalene) in Corynebacterium sp. strain C125.
PubMed:Identification of different mechanisms of action for increases of food intake and plasma ACTH concentration following 5-HT1a receptor subtype activation in rat brain.
PubMed:Effects of buspirone and ipsapirone on schedule induced polydipsia: comparison with 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) and raclopride.
PubMed:Ipsapirone and 8-OH-DPAT reduce ethanol preference in rats: involvement of presynaptic 5-HT1A receptors.
PubMed:The discriminative stimulus properties of buspirone involve dopamine-2 receptor antagonist activity.
PubMed:Effects of intracisternal vs. intrahypothalamic 5,7-DHT on feeding elicited by hypothalamic infusion of NE.
PubMed:Behavioral profile of the 5HT1A receptor antagonist (S)-UH-301 in rodents and monkeys.
PubMed:Effects of the 5-HT1A agonist 8-OH-DPAT on food intake in food-deprived rats.
PubMed:Are 5-HT receptors or beta-adrenoceptors involved in idazoxan-induced food and water intake?
PubMed:Effects of the putative 5-HT1A receptor antagonist NAN-190 on free feeding and on feeding induced by the 5-HT1A receptor agonist 8-OH-DPAT in the rat.
PubMed:The 5-HT1A agonist 8-OH-DPAT attenuates the satiating action of cholecystokinin.
PubMed:A comparison of the effects of the 5-HT1 agonists TFMPP and RU 24969 on feeding following peripheral or medial hypothalamic injection.
PubMed:Increased rates of punished responding produced by buspirone-like compounds in rats.
PubMed:Effects of the membrane action of tetralin on the functional and structural properties of artificial and bacterial membranes.
PubMed:Discriminative stimulus properties of the serotonergic compound eltoprazine.
PubMed:Effects of the 5HT1A agonist, 8-OH-DPAT, on operant food intake in non-deprived rats.
PubMed:Evidence for differential effects of 8-OH-DPAT on male and female rats in the Anxiety/Defense Test Battery.
PubMed:Effect of drugs influencing 5-HT function on ethanol drinking and feeding behaviour in rats: studies using a drinkometer system.
PubMed:Repeated corticosterone treatment attenuates behavioural and neuroendocrine responses to 8-hydroxy-2-(di-n-propylamino) tetralin in rats.
PubMed:Low doses of the 5-HT1A receptor agonist 8-OH-DPAT increase ingestive behavior in late preweanling and postweanling, but not neonatal rat pups.
PubMed:Spontaneous alternation behavior: an animal model for obsessive-compulsive disorder?
PubMed:Impairment of glucostatic, adrenergic and serotoninergic feeding parallels the lack of glucoprivic signals in the golden hamster.
PubMed:Dopamine receptor blockade in nucleus accumbens or caudate nucleus differentially affects feeding induced by 8-OH-DPAT injected into dorsal or median raphe.
PubMed:Hypothalamic monoamines and food intake in alcohol-preferring AA and alcohol-avoiding ANA rats.
PubMed:Peripheral 5-carboxamidotryptamine (5-CT) elicits drinking by stimulating 5-HT1-like serotonergic receptors in rats.
PubMed:Long-term administration of m-chlorophenylpiperazine to rats does not alter functional sensitivity of either pre-synaptic or postsynaptic 5-HT1A receptors.
PubMed:Effects of tryptophan and of 5-hydroxytryptamine receptor subtype agonists on feeding.
PubMed:Effects of 5-HT-1A receptor agonists on CRF-induced behavior.
PubMed:5-HT1A agonists and dopamine: the effects of 8-OH-DPAT and buspirone on brain-stimulation reward.
PubMed:Influence of taste and food texture on the feeding responses induced by 8-OH-DPAT and gepirone.
PubMed:Serotonin release in lateral and medial hypothalamus during feeding and its anticipation.
PubMed:Behavioral mechanisms for the anorectic action of the serotonin (5-HT) uptake inhibitor sertraline in rats: comparison with directly acting 5-HT agonists.
PubMed:Dorsal raphe microinjection of 5-HT and indirect 5-HT agonists induces feeding in rats.
PubMed:Effects of systemic 8-OH-DPAT on the feeding induced by hypothalamic NE infusion.
PubMed:Effects of buspirone and related compounds on suppressed operant responding in rats.
PubMed:Repeated treatment with imipramine, amitriptyline or electroconvulsive shock does not affect the 8-OH-DPAT-induced increase in food intake in free feeding rats.
PubMed:The involvement of 5-hydroxytryptaminergic and dopaminergic mechanisms in the eating induced by buspirone, gepirone and ipsapirone.
PubMed:Single and combined effects of desimipramine and lithium on serotonergic receptor number and second messenger function in rat brain.
PubMed:Effects of 8-OH-DPAT, buspirone and ICS 205-930 on feeding in a novel environment: comparisons with chlordiazepoxide and FG 7142.
PubMed:8-OH-DPAT specifically enhances feeding behaviour in mice: evidence from behavioural competition.
PubMed:Selective increase in carbohydrate intake by rats treated with 8-hydroxy-2-(di-n-propylamino)-tetraline or buspirone.
PubMed:A pharmacological analysis of the eating response induced by 8-OH-DPAT injected into the dorsal raphé nucleus reveals the involvement of a dopaminergic mechanism.
PubMed:Spiroxatrine augments fluoxetine-induced reduction of ethanol intake by the P line of rats.
PubMed:Long-term cortisol treatment impairs behavioral and neuroendocrine responses to 5-HT1 agonists in the rat.
PubMed:Dextrofenfluramine, but not 8-OH-DPAT affects the decrease in food consumed by rats submitted to physical exercise.
PubMed:Blockade of 8-OH-DPAT-induced feeding by dopamine antagonists.
PubMed:A comparison of feeding and locomotion responses to serotonin agonists in three rat strains.
PubMed:Feeding responses to a high dose of 8-OH-DPAT in young and adult rats: influence of food texture.
PubMed:Effects of buspirone differ from those of gepirone and 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) on unpunished responding of pigeons.
PubMed:Behavioral studies with anxiolytic drugs. V. Behavioral and in vivo neurochemical analyses in pigeons of drugs that increase punished responding.
PubMed:Evidence that the hyperphagic response to 8-OH-DPAT is mediated by 5-HT1A receptors.
PubMed:Hyperinsulinemia of the genetically obese (fa/fa) rat is decreased by a low dose of the 5-HT1A receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT).
PubMed:Food intake, neuroendocrine and temperature effects of 8-OHDPAT in the rat.
PubMed:8-OH-DPAT elicits feeding and not chewing: evidence from liquid diet studies and a diet choice test.
PubMed:Fawn hooded rats are subsensitive to the food intake suppressant effects of 5-HT agonists.
PubMed:The 5-HT1A agonist 8-OH-DPAT increases consumption of palatable wet mash and liquid diets in the rat.
PubMed:Behavioural specificity of 8-OH-DPAT-induced feeding.
PubMed:Relationship of increased food intake and plasma ACTH levels to 5-HT1A receptor activation in rats.
PubMed:Behavioral studies with anxiolytic drugs. IV. Serotonergic involvement in the effects of buspirone on punished behavior of pigeons.
PubMed:5-HT1A and alpha-2 adrenergic receptors mediate the hyperglycemic and hypoinsulinemic effects of 8-hydroxy-2-(di-n-propylamino)tetralin in the conscious rat.
PubMed:Serotonin and feeding responses of rats to amino acid imbalance: initial phase.
PubMed:The role of putative 5-HT1A and 5-HT1B receptors in the control of feeding in rats.
PubMed:The effects of 8-hydroxy-2-(di-n-propylamino)tetralin and other serotonergic agonists on performance in a radial maze: a possible role for 5-HT1A receptors in memory.
PubMed:Discriminative stimulus properties of buspirone in the pigeon.
PubMed:8-OH-DPAT elicits gnawing, and eating of solid but not liquid foods.
PubMed:Neurochemical and behavioural evidence for mediation of the hyperphagic action of 8-OH-DPAT by 5-HT cell body autoreceptors.
PubMed:Para-chlorophenylalanine prevents feeding induced by the serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT).
PubMed:Neurochemical mechanism of action of drugs which modify feeding via the serotoninergic system.
PubMed:Characteristics of feeding induced by the serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT).
PubMed:Low doses of the putative serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) elicit feeding in the rat.
PubMed:Modified flotation technique for quantitative determination of mite populations in feedstuffs.
PubMed:The pathogenesis of primary internodal demyelination produced by acetyl ethyl tetramethyl tetralin: evidence for preserved Schwann cell somal function.
PubMed:Flotation technique for quantitative determination of mite populations in powdered and compacted foodstuffs.
 
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