hexamethyldisilazane
bis(trimethylsilyl)amine

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  Product(s):
  HEXAMETHYLDISILAZANE

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  Product(s):
  H0089 1,1,1,3,3,3-Hexamethyldisilazane >96.0%(GC)
  SDS

CAS Number: 999-97-3 3D/inchi Other(deleted CASRN): 103737-28-6 ECHA EINECS - REACH Pre-Reg: 213-668-5 FDA UNII: H36C68P1BH Nikkaji Web: J7.217F Beilstein Number: 635752 MDL: MFCD00008259 Molecular Weight: 161.39503000 Formula: C6 H19 N Si2 NMR Predictor: Predict (works with chrome, Edge or firefox) Category:indirect food additives: adhesives and components of coatings   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search DG SANTE Food Contact Materials: hexamethyldisilazane   Physical Properties: Appearance: colorless to pale yellow clear liquid (est) Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Specific Gravity: 0.77400 to 0.77800 @ 20.00 °C. Pounds per Gallon - (est).: 6.448 to 6.481 Refractive Index: 1.40600 to 1.41000 @ 20.00 °C. Boiling Point: 125.00 °C. @ 760.00 mm Hg Vapor Pressure: 13.800000 mmHg @ 25.00 °C. Flash Point: 48.00 °F. TCC ( 8.89 °C. ) Soluble in:   water, 392.3 mg/L @ 25 °C (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: Charkit Chemical HEXAMETHYLDISILAZANE Sigma-Aldrich: Aldrich For experimental / research use only. Hexamethyldisilazane ReagentPlus®, 99.9% sds TCI AMERICA For experimental / research use only. 1,1,1,3,3,3-Hexamethyldisilazane >96.0%(GC) sds   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: intravenous-mouse LD50 > 100 mg/kg Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974 oral-mouse LD50 850 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION CARDIAC: PULSE RATE BEHAVIORAL: GENERAL ANESTHETIC Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986. intraperitoneal-mouse LDLo 650 mg/kg IMMUNOLOGICAL INCLUDING ALLERGIC: DECREASED IMMUNE RESPONSE Personal Communication from G.D. Stoner, Dept. of Community Medicine, School of Medicine, Univ. of California, La Jolla, CA 92037, May 25, 1975Vol. 27MAY1975 oral-rabbit LD50 1100 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION CARDIAC: PULSE RATE BEHAVIORAL: GENERAL ANESTHETIC Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986. intraperitoneal-rat LD50 800 mg/kg SKIN AND APPENDAGES (SKIN): HAIR: OTHER BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: TREMOR National Technical Information Service. Vol. OTS0537734 oral-rat LD50 850 mg/kg LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION CARDIAC: PULSE RATE BEHAVIORAL: GENERAL ANESTHETIC Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986. Dermal Toxicity: skin-guinea pig LD50 1 mL/kg BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: TREMOR SKIN AND APPENDAGES (SKIN): HAIR: OTHER National Technical Information Service. Vol. OTS0537734 skin-rabbit LD50 710 uL/kg GASTROINTESTINAL: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 12, Pg. 576, 1993. Inhalation Toxicity: inhalation-mouse LC50 12000 mg/m3/2H BEHAVIORAL: GENERAL ANESTHETIC LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION CARDIAC: PULSE RATE Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986. inhalation-rat LC50 8700 mg/m3/4H CARDIAC: PULSE RATE BEHAVIORAL: GENERAL ANESTHETIC LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 30(5), Pg. 52, 1986.   Safety in Use Information: Category: indirect food additives: adhesives and components of coatings Recommendation for hexamethyldisilazane usage levels up to:   not for fragrance use.   Recommendation for hexamethyldisilazane flavor usage levels up to:   not for flavor use.   Safety References: European Food Safety Authority (EFSA) reference(s): Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to the 14th list of substances for food contact materials View page or View pdf Scientific Opinion on the safety assessment of the substances tetraethyl orthosilicate, CAS No. 78-10-4, and hexamethyldisilazane, CAS No. 999 97 3, for use in food contact materials View page or View pdf EPI System: View Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA Substance Registry Services (TSCA):999-97-3 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :13838 National Institute of Allergy and Infectious Diseases:Data WGK Germany:2 [dimethyl-(trimethylsilylamino)silyl]methane Chemidplus:0000999973 EPA/NOAA CAMEO:hazardous materials RTECS:JM9230000 for cas# 999-97-3   References:   [dimethyl-(trimethylsilylamino)silyl]methane NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 999-97-3 Pubchem (cid): 13838 Pubchem (sid): 134979420   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Indirect Additives used in Food Contact Substances: View CHEBI: View CHEMBL: View HMDB (The Human Metabolome Database): Search Export Tariff Code: 2931.90.9010 ChemSpider: View Wikipedia: View   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms: [ dimethyl-(trimethylsilylamino)silyl]methane   disilazane, hexamethyl- 1,1,1,3,3,3- hexamethyl disilazane 1,1,1,3,3,3- hexamethyldisilazane bis(t rimethylsilyl)amine   Articles:   None found yet. Try the PubMed Search.

Notes: None found