EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

1-propanethiol, 3-(trimethoxysilyl)-

Supplier Sponsors

CAS Number: 4420-74-0Picture of molecule3D/inchi
Other(deleted CASRN):161756-15-6
ECHA EINECS - REACH Pre-Reg:224-588-5
Nikkaji Web:J8.721A
Beilstein Number:2038119
Molecular Weight:196.34142000
Formula:C6 H16 O3 S Si
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:nail conditioning agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.03900 @ 25.00 °C.
Boiling Point: 198.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.500000 mmHg @ 25.00 °C. (est)
Flash Point: 120.00 °F. TCC ( 48.89 °C. )
logP (o/w): 1.090 (est)
Soluble in:
 water, 2.77e+004 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: nail conditioning
For experimental / research use only.
Santa Cruz Biotechnology
For experimental / research use only.
(3-Mercaptopropyl)trimethoxysilane 95%
Sigma-Aldrich: Aldrich
For experimental / research use only.
(3-Mercaptopropyl)trimethoxysilane 95%
For experimental / research use only.
(3-Mercaptopropyl)trimethoxysilane >96.0%(GC)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 633 mg/kg
Doklady Akademii Nauk SSSR. Proceedings of the Academy of Sciences of the USSR. For English translation, see DBIOAM and DKBSAS. Vol. 229, Pg. 1011, 1976.

oral-rat LD50 730 uL/kg
Journal of Toxicology, Cutaneous and Ocular Toxicology. Vol. 15, Pg. 261, 1996.

Dermal Toxicity:
skin-rabbit LD50 2140 uL/kg
Journal of Toxicology, Cutaneous and Ocular Toxicology. Vol. 15, Pg. 261, 1996.

Inhalation Toxicity:
Not determined
Safety in Use Information:
nail conditioning agents
Recommendation for mercaptopropyltrimethoxysilane usage levels up to:
 not for fragrance use.
Recommendation for mercaptopropyltrimethoxysilane flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):4420-74-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :20473
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
RTECS:TZ7800000 for cas# 4420-74-0
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:4420-74-0
Pubchem (cid):20473
Pubchem (sid):134984788
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2931.90.9010
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
 GF 70
 KBE 803
 KBM 803
 M 8500
(3-mercaptopropyl) trimethoxysilane
 NUCA 189
1-propanethiol, 3-(trimethoxysilyl)-
 prosil 196
 SH 6062
 sila-ace S 810
 silane A 189
 silane, 3-mercaptopropyltrimethoxy-
 silquest A 189
3-(trimethoxysilyl)propyl mercaptan
 union carbide A-189


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None found
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