EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

(±)-tetrahydrofurfuryl methacrylate
methacrylic acid, tetrahydrofurfuryl ester (8CI)

Supplier Sponsors

Name:oxolan-2-ylmethyl 2-methylprop-2-enoate
CAS Number: 2455-24-5Picture of molecule3D/inchi
Other(deleted CASRN):125166-24-7
ECHA EINECS - REACH Pre-Reg:219-529-5
FDA UNII: 120GN9C472
Nikkaji Web:J208.715D
XlogP3-AA:1.50 (est)
Molecular Weight:170.20818000
Formula:C9 H14 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.04400 @ 25.00 °C.
Refractive Index:1.45800 @ 20.00 °C.
Boiling Point: 265.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.161000 mmHg
Flash Point: 195.00 °F. TCC ( 90.56 °C. )
logP (o/w): 1.380 (est)
Soluble in:
 water, 1792 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: film formers
Santa Cruz Biotechnology
For experimental / research use only.
(±)-Tetrahydrofurfuryl Methacrylate 97%
Sigma-Aldrich: Aldrich
For experimental / research use only.
(±)-Tetrahydrofurfuryl Methacrylate 97%
contains 75 ppm HQ as inhibitor, 900 ppm MEHQ as inhibitor
For experimental / research use only.
(±)-Tetrahydrofurfuryl Methacrylate (stabilized with MEHQ) >95.0%(GC)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic agents
Recommendation for (±)-tetrahydrofurfuryl methacrylate usage levels up to:
 not for fragrance use.
Recommendation for (±)-tetrahydrofurfuryl methacrylate flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):2455-24-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :17151
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
oxolan-2-ylmethyl 2-methylprop-2-enoate
 oxolan-2-ylmethyl 2-methylprop-2-enoate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:2455-24-5
Pubchem (cid):17151
Pubchem (sid):134982226
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2916.14.2050
EFSA Update of results on the monitoring of furan levels in food:Read Report
EFSA Previous report: Results on the monitoring of furan levels in food:Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food:Read Report
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
 methacrylic acid tetrahydrofurfuryl ester
 methacrylic acid, tetrahydrofurfuryl ester
 methacrylic acid, tetrahydrofurfuryl ester (8CI)
2-methyl-acrylic acid tetrahydro-furan-2-ylmethyl ester
 oxolan-2-ylmethyl 2-methylprop-2-enoate
2-propenoic acid, 2-methyl-, (tetrahydro-2-furanyl)methyl ester
 tetrahydro-2-furanylmethyl methacrylate
 tetrahydrofuran-2-ylmethyl 2-methylprop-2-enoate
 tetrahydrofuran-2-ylmethyl methacrylate
(±)-tetrahydrofurfuryl methacrylate


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PubMed:Chlorhexidine-impregnated PEM/THFM polymer exhibits superior activity to fluconazole-impregnated polymer against Candida albicans biofilm formation.
PubMed:Impregnation with antimicrobials challenge bonding properties and water sorption behaviour of an acrylic liner.
PubMed:Fungicidal amounts of antifungals are released from impregnated denture lining material for up to 28 days.
PubMed:Reactivity of Monovinyl (Meth)Acrylates Containing Cyclic Carbonates.
PubMed:Biomimetic potential of some methacrylate-based copolymers: a comparative study.
PubMed:Occupational methacrylate and acrylate allergy from glues.
PubMed:The biocompatibility and osteoconductivity of a cement containing beta-TCP for use in vertebroplasty.
PubMed:Final report of the safety assessment of methacrylate ester monomers used in nail enhancement products.
PubMed:Mass uptake study of the diffusion of water and SBF into poly(2-hydroxyethyl methacrylate-co-tetrahydrofurfuryl methacrylate) containing aspirin or vitamin B12.
PubMed:Water sorption behaviour of polymeric systems based on tetrahydrofurfuryl methacrylate.
PubMed:NMR imaging of the diffusion of water at 310 K into semi-IPNs of PEM and poly(HEMA-co-THFMA) with and without chlorhexidine diacetate.
PubMed:Porous methacrylate scaffolds: supercritical fluid fabrication and in vitro chondrocyte responses.
PubMed:(1)H NMR study of the states of water in equilibrium poly(HEMA-co-THFMA) hydrogels.
PubMed:PFG-NMR measurements of the self-diffusion coefficients of water in equilibrium poly(HEMA-co-THFMA) hydrogels.
PubMed:The role of protein adsorption on chondrocyte adhesion to a heterocyclic methacrylate polymer system.
PubMed:NMR imaging of water sorption into poly(hydroxyethyl methacrylate-co-tetrahydrofurfuryl methacrylate).
PubMed:Osteoblast cell death on methacrylate polymers involves apoptosis.
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PubMed:Release of recombinant human bone morphogenetic protein-2 from heterocyclic methacrylate polymer systems.
PubMed:Water absorption and surface properties of novel poly(ethylmethacrylate) polymer systems for use in bone and cartilage repair.
PubMed:The effect of two hydrophilic monomers on the water uptake of a heterocyclic methacrylate system.
PubMed:Chlorhexidine release from room temperature polymerising methacrylate systems.
PubMed:An in vitro investigation of the PEMA/THFMA polymer system as a biomaterial for cartilage repair.
PubMed:3He ion-beam analysis of water uptake and drug delivery.
PubMed:Attachment of cultured human bone cells to novel polymers.
PubMed:The water uptake of poly(tetrahydrofurfuryl methacrylate).
PubMed:Fluoride ion release from two methacrylate polymer systems.
PubMed:A methacrylate-based cement used as a root canal sealer.
PubMed:Monomethacrylate co-monomers for dental resins.
PubMed:THFMA in dental monomer systems.
PubMed:Modifications of the hydrophilicity of heterocyclic methacrylate copolymers for protein release.
PubMed:Occupational allergic contact dermatitis from 2-hydroxyethyl methacrylate and ethylene glycol dimethacrylate in a modified acrylic structural adhesive.
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PubMed:Study of polymeric systems based on 2,2 bis-4(2-hydroxy-3-methacryloyl-oxypropoxy) phenyl propane.
PubMed:Cross-linking and ring opening during polymerization of heterocyclic methacrylates and acrylates.
None found
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