D-mevalonolactone, 19115-49-2

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CODE113605 CODE113605
Product(s):
19115-49-2 (R)-Mevalonolactone >90.0%(GC)

Name:	(4R)-4-hydroxy-4-methyloxan-2-one
CAS Number:	19115-49-2	3D/inchi
FDA UNII:	661X270Z3L
Nikkaji Web:	J37.661B
MDL:	MFCD01074894
XlogP3:	-0.30 (est)
Molecular Weight:	130.14330000
Formula:	C6 H10 O3
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:information only not used for fragrances or flavors

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Soluble in:
	water, 1e+006 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

BOC Sciences

For experimental / research use only.

(R)-Mevalonolactone >90.0%(GC)

Santa Cruz Biotechnology

For experimental / research use only.

(R)-Mevalonolactone ≥90%

Sigma-Aldrich: Sigma

For experimental / research use only.

(R)-(-)-Mevalonolactone ≥90.0% (GC)

sds

Safety Information:

Preferred SDS: View

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
information only not used for fragrances or flavors
Recommendation for D-mevalonolactone usage levels up to:
	not for fragrance use.

Recommendation for D-mevalonolactone flavor usage levels up to:
	not for flavor use.

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :6419891

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

(4R)-4-hydroxy-4-methyloxan-2-one

Chemidplus:0019115492

References:

	(4R)-4-hydroxy-4-methyloxan-2-one
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	6419891
Pubchem (sid):	163639800

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEBI:	View
CHEMBL:	View
HMDB (The Human Metabolome Database):	Search
ChemSpider:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

not found in nature

Synonyms:

(4R)-4-	hydroxy-4-methyloxan-2-one
(4R)-4-	hydroxy-4-methyltetrahydro-2H-pyran-2-one
b-	hydroxy-b-methyl-d-valerolactone
(-)-(R)-	mevalonic acid lactone
D-	mevalonic Acid Lactone
(-)-	mevalonolactone
(-)-(R)-	mevalonolactone
(3R)-	mevalonolactone
(R)-	mevalonolactone
	mevalonolactone, (-)-
	mevalonolactone, (R)-isomer
2H-	pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (4R)-
2H-	pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (R)-

Articles:

PubMed:(-)-R-mevalonolactone studied by ROA and SERS spectroscopy.

PubMed:Polyketides from the littoral plant associated fungus Pseudallescheria boydii.

PubMed:A mild, palladium-catalyzed method for the dehydrohalogenation of alkyl bromides: synthetic and mechanistic studies.

PubMed:Cytotoxic pentacyclic and tetracyclic aromatic sesquiterpenes from Phomopsis archeri.

PubMed:Cytotoxic cardenolides from the leaves of Calotropis gigantea.

PubMed:Cloning and characterization of a novel gene that encodes (S)-beta-bisabolene synthase from ginger, Zingiber officinale.

PubMed:Cytotoxic substances produced by a fungal strain from a sponge: physico-chemical properties and structures.

PubMed:Feasibility of an immunoassay for mevalonolactone.

PubMed:Chloroperoxidase as Enantioselective Epoxidation Catalyst: An Efficient Synthesis of (R)-(-)-Mevalonolactone.

PubMed:Regulation of cholesterol synthesis in primary rat hepatocyte culture cells. Possible regulatory site at sterol demethylation.

Notes:

None found

D-mevalonolactone 2H-pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (4R)-

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Articles:

D-mevalonolactone
2H-pyran-2-one, tetrahydro-4-hydroxy-4-methyl-, (4R)-