EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

amaranth (c.i. 16185 (Na))
3-hydroxy-4-[(4-sulfo-1-naphthalenyl)azo]-2,7-naphthalenedisulfonic acid trisodium salt

Supplier Sponsors

CAS Number: 915-67-3Picture of molecule3D/inchi
Other(deleted CASRN):11139-84-7
ECHA EINECS - REACH Pre-Reg:213-022-2
FDA UNII: 37RBV3X49K
Beilstein Number:4122311
MDL:MFCD00004076
Molecular Weight:604.47797784
Formula:C20 H11 N2 Na3 O10 S3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:coloring agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
EU SANCO Amaranth View - review
JECFA Food Additive: Amaranth
GSFA Codex: Amaranth (123)
DG SANTE Food Additives:amaranth (c.i. 16185 (Na))
FDA Mainterm (SATF):915-67-3 ; FD&C RED NO. 2--DELISTED
FDA Regulation:
FDA PART 81 -- GENERAL SPECIFICATIONS AND GENERAL RESTRICTIONS FOR PROVISIONAL COLOR ADDITIVES FOR USE IN FOODS, DRUGS,
AND COSMETICS
Sec. 81.10 Termination of provisional listings of color additives


FDA PART 81 -- GENERAL SPECIFICATIONS AND GENERAL RESTRICTIONS FOR PROVISIONAL COLOR ADDITIVES FOR USE IN FOODS, DRUGS,
AND COSMETICS
Sec. 81.30 Cancellation of certificates.
 
Physical Properties:
Appearance:reddish brown to dark reddish brown powder (est)
Assay: 85.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 6.00E+04 mg/L @ 25 °C (exp)
Insoluble in:
 alcohol, slightly
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: cosmetic colorants
 
Suppliers:
BOC Sciences
For experimental / research use only.
Amaranth > 95%
Odor: characteristic
Use: Azo Rubine is an synthetic red food dye and is used for the purposes where food is heat-treated after fermentation.
Glentham Life Sciences
Azorubine S (C.I. 16185)
Kishi Kasei
Red No.2
Rung International
Amaranth
Rung International
Lake Amaranth
Santa Cruz Biotechnology
For experimental / research use only.
Amaranth
Sigma-Aldrich: Sigma
For experimental / research use only.
Amaranth Dye content 85-95 %
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-rat LD50 1000 mg/kg
Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979.

intraperitoneal-rat LD50 1000 mg/kg
Scientia Pharmaceutica. Vol. 47, Pg. 39, 1979.

intraperitoneal-mouse LD50 1000 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Food and Cosmetics Toxicology. Vol. 14, Pg. 163, 1976.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
coloring agents
Recommendation for amaranth (c.i. 16185 (Na)) usage levels up to:
 not for fragrance use.
 
Recommendation for amaranth (c.i. 16185 (Na)) flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the re-evaluation of Amaranth (E 123) as a food additive
View page or View pdf

Statement on Allura Red AC and other sulphonated mono azo dyes authorised as food and feed additives
View page or View pdf

Refined exposure assessment for amaranth (E 123)
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):915-67-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :6093196
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
trisodium (4E)-3-oxo-4-[(4-sulfonatonaphthalen-1-yl)hydrazinylidene]naphthalene-2,7-disulfonate
Chemidplus:0000915673
EPA/NOAA CAMEO:hazardous materials
RTECS:QJ6550000 for cas# 915-67-3
 
References:
 trisodium (4E)-3-oxo-4-[(4-sulfonatonaphthalen-1-yl)hydrazinylidene]naphthalene-2,7-disulfonate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:915-67-3
Pubchem (cid):6093196
Pubchem (sid):134980072
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:3204.12.5000
FDA Listing of Food Additive Status:View
FDA Color Additive Status ListView
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 cosmetic colorants
 hair dyeing agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 1302 red
 1508 red
 acid amaranth I
 acid amaranth J
 acid amaranth N
 acid leather red I 2BW
 acid leather rubine S
 acid red 27
 acid red 27 (c.i. 16185 (Na))
 acid red 27 trisodium salt
 aizen amaranth
 amacid amaranth
 amaranth 85
 amaranth A
 amaranth B
 amaranth lake
 amaranth R
 amaranth S
 amaranth WD
 azo red R
 azo rubine S-FQ
 azo rubine SF
 azo ruby S
 azorubin S
 azorubin s (c.i. 16185 (Na))
 bordeaux S
 c.i. 16185 (Na)
 C.I. acid red 27
 C.I. food red 9
 certicol amaranth S
 ci 16185 (Na)
 colour index, food red 9
 cranberry red
 D&C Red No. 2
 daishiki amaranth
 dolkwal amaranth
 dye red raspberry
 edicol amaranth
 edicol supra amaranth A
 eurocert amaranth
 food red 9
 hexacert red no. 2
 hexacol amaranth B extra
 hidacid amaranth
 hispacid red AM
3-hydroxy-4-((4-sulfo-1-naphthalenyl)azo)-2,7-naphthalenedisulfonic acid trisodium salt
3-hydroxy-4-[(4-sulfo-1-naphthalenyl)azo]-2,7-naphthalenedisulfonic acid trisodium salt
 japan food red no. 2
 japan red 2
 japan red no. 2
 java amaranth
 kayaku amaranth
 kayaku food colour red no. 2
 kca foodcol amaranth A
 kiton rubine S
 lissamine amaranth AC
 maple amaranth
2,7-naphthalenedisulfonic acid, 3-hydroxy-4-((4-sulfo-1-naphthalenyl)azo)-, trisodium salt
2,7-naphthalenedisulfonic acid, 3-hydroxy-4-((4-sulfo-1-naphthyl)azo)-, trisodium salt
2,7-naphthalenedisulfonic acid, 3-hydroxy-4-[(4-sulfo-1-naphthyl)azo]-, trisodium salt
2,7-naphthalenedisulfonic acid, 3-hydroxy-4-[(E)-2-(4-sulfo-1-naphthalenyl)diazenyl]-, sodium salt (1:3)
 naphthol red LZS
 naphthol red S
 neklacid red A
 rakuto amaranth
 rouge solid E
 san-ei amaranth
 shikiso amaranth
 solar red O
1-(4-sulfo-1-naphthylazo)-2-naphthol-3,6-disulfonic acid trisodium salt
 takaoka amaranth
 tertracid red A
 toyo amaranth
 trisodium (4E)-3-oxo-4-[(4-sulfonatonaphthalen-1-yl)hydrazinylidene]naphthalene-2,7-disulfonate
 trisodium 3-hydroxy-4-(4'-sulfonatonaphthyl azo) naphthalene-2,7-disulfonate
 trisodium 3-hydroxy-4-[(E)-(4-sulfonato-1-naphthyl)diazenyl]-2,7-naphthalenedisulfonate
 trisodium 3-hydroxy-4-[(E)-(4-sulfonato-1-naphthyl)diazenyl]naphthalene-2,7-disulfonate
 trisodium 3-hydroxy-4-[(E)-(4-sulfonatonaphthalen-1-yl)diazenyl]naphthalene-2,7-disulfonate
 trisodium salt of 1-(4-sulfo-1-naphthylazo)-2-naphthol-3,6-disulfonic acid
 
 
Notes:
a sulfonic acid-based naphthylazo dye used as a coloring agent for foodstuffs and medicines and as a dye and chemical indicator. it was banned by the fda in 1976 for use in foods, drugs, and cosmetics. (from merck index, 11th ed)
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