disodium EDTA
sodium N,N'-ethane-1,2-diylbis(N-(carboxymethyl)glycinate)
 
Notes:
Preservative and sequestrant in foods Ethylenediaminetetraacetic acid, widely abbreviated as EDTA, is a polyamino carboxylic acid and a colourless, water-soluble solid. Its conjugate base is named ethylenediaminetetraacetate. It is widely used to dissolve limescale. Its usefulness arises because of its role as a hexadentate ("six-toothed") ligand and chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+. After being bound by EDTA, metal ions remain in solution but exhibit diminished reactivity. EDTA is produced as several salts, notably disodium EDTA and calcium disodium EDTA. (Wikipedia) Chelating agent used in food processing Ethylenediaminetetraacetic acid, widely abbreviated as EDTA, is a polyamino carboxylic acid and a colourless, water-soluble solid. Its conjugate base is named ethylenediaminetetraacetate. It is widely used to dissolve limescale. Its usefulness arises because of its role as a hexadentate ("six-toothed") ligand and chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+. After being bound by EDTA, metal ions remain in solution but exhibit diminished reactivity. EDTA is produced as several salts, notably disodium EDTA and calcium disodium EDTA. (Wikipedia) Sequestrant, preservative and discolouration inhibitor for foods Ethylenediaminetetraacetic acid, widely abbreviated as EDTA, is a polyamino carboxylic acid and a colourless, water-soluble solid. Its conjugate base is named ethylenediaminetetraacetate. It is widely used to dissolve limescale. Its usefulness arises because of its role as a hexadentate ("six-toothed") ligand and chelating agent, i.e. its ability to "sequester" metal ions such as Ca2+ and Fe3+. After being bound by EDTA, metal ions remain in solution but exhibit diminished reactivity. EDTA is produced as several salts, notably disodium EDTA and calcium disodium EDTA. (Wikipedia)
  • Charkit Chemical
    • Charkit Chemical Corporation
      The Specialty Chemical Specialists
      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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      Product(s):
      DISODIUM EDTA, USP
       
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    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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      Product(s):
      05-00205 EDETATE DISODIUM DIHYDRATE, Kosher
       
Synonyms   Articles   Notes   Search
disodium 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)amino]ethyl]amino]acetate (Click)
CAS Number: 139-33-3Picture of molecule
ECHA EINECS - REACH Pre-Reg: 205-358-3
FDA UNII: 8NLQ36F6MM
Beilstein Number: 3822669
MDL: MFCD00070672
Molecular Weight: 336.20871856
Formula: C10 H14 N2 Na2 O8
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: sequestrant, antioxidant synergist, preservative
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 363 Calcium disodium ethylenediaminetetraacetic acid (EDTA) and disodium EDTA View-notice PDF
JECFA Food Additive: Disodium Ethylenediaminetetraacetate
GSFA Codex: Disodium ethylenediaminetetraacetate (386)
FDA Mainterm: EDTA, DISODIUM
FDA Regulation:
FDA PART 155 -- CANNED VEGETABLES
Subpart B--Requirements for Specific Standardized Canned Vegetables
Sec. 155.200 Certain other canned vegetables.


FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS
Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings
Sec. 169.115 French dressing.


FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS
Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings
Sec. 169.140 Mayonnaise.


FDA PART 169 -- FOOD DRESSINGS AND FLAVORINGS
Subpart B--Requirements for Specific Standardized Food Dressings and Flavorings
Sec. 169.150 Salad dressing.


FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart B--Food Preservatives
Sec. 172.120 Calcium disodium EDTA.


FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart B--Food Preservatives
Sec. 172.135 Disodium EDTA.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.150 Chelating agents used in the manufacture of paper and paperboard.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1200 Cellophane.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart B--Substances Utilized To Control the Growth of Microorganisms
Sec. 178.1010 Sanitizing solutions.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart D--Certain Adjuvants and Production Aids
Sec. 178.3570 Lubricants with incidental food contact.


FDA PART 573 -- FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS
Subpart B--Food Additive Listing
Sec. 573.360 Disodium EDTA.


FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION
Subpart A--Foods
Sec. 73.1 Diluents in color additive mixtures for food use exempt from certification.
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: white crystalline powder (est)
Assay: 99.00 to 100.00 % 
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Insoluble in:
 alcohol
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Organoleptic Properties:
Odor Description:
at 100.00 %. 
odorless
  
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: chelating agents
viscosity controlling agents
Synonyms   Articles   Notes   Search   Top
Suppliers:
American Elements
Disodium Dihydrogen Ethylenediaminetetraacetate Solution 99%
Odor: characteristic
Use: Disodium Dihydrogen Ethylenediaminetetraacetate Solution is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
BOC Sciences
For experimental / research use only.
Ethylenediaminetetraacetic acid disodium salt
Charkit Chemical
DISODIUM EDTA, USP
Connect Chemicals
Ethylenediaminetetraacetic acid disodium salt (EDTA 2Na)
Odor: characteristic
Use: Ethylenediaminetetraacetic acid disodium salt (EDTA 2Na) is used in detergents, liquid soap, shampoo, agricultural chemicals, fixer solution for development of color film, water cleaner, pH modifier. When stating the redox reaction for the polymerization of butyl benzene rubber, it is used as part of activator for the control of polymerization speed.
Galaxy Surfactants North America
DISSOLVINE NA2-P
Galaxy Surfactants North America
DISSOLVINE NA2-S
Graham Chemical
Disodium Ethylenediamine, Tetraacetate Dihydrate
Kraft Chemical
Disodium EDTA
Penta International
EDETATE DISODIUM DIHYDRATE, Kosher
Prinova
Edta Na2p Disodium
Santa Cruz Biotechnology
For experimental / research use only.
Ethylenediaminetetraacetic acid disodium salt solution
Sigma-Aldrich
For experimental / research use only.
Ethylenediaminetetraacetic acid disodium salt solution
for molecular biology, 0.5 M in H2O, DNase, RNase, NICKase and protease, none detected
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  2000 mg/kg
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 27, Pg. 465, 1968.

oral-rabbit LD50  2300 mg/kg
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 113, 1956.

intravenous-rabbit LD50  47 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 113, 1956.

oral-mouse LD50  2050 mg/kg
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 126S, 1956.

intravenous-mouse LD50  56 mg/kg
U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03781

intraperitoneal-mouse LD50  260 mg/kg
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 52, Pg. 126S, 1956.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: sequestrant, antioxidant synergist, preservative
Recommendation for disodium EDTA usage levels up to:
 not for fragrance use.
 
Recommendation for disodium EDTA flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
ClinicalTrials.gov: search
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
EPA GENetic TOXicology: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 139-33-3
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 8759
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 disodium 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)amino]ethyl]amino]acetate
Chemidplus: 0000139333
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References:
 disodium 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)amino]ethyl]amino]acetate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 139-33-3
Pubchem (cid): 8759
Pubchem (sid): 134974234
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
CHEMBL: View
KEGG (GenomeNet): D03945
HMDB (The Human Metabolome Database): Search
FooDB: FDB015445
Household Products: Search
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Formulations/Preparations:
•the cosmetic-grade material contains a minimum of 99.0% tetrasodium edta as na4edta.2h2o •anhydrous or dihydrate.
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
None Found
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 not found in nature
Synonyms   Articles   Notes   Search   Top
Synonyms:
 disodium 2-[carboxymethyl-[2-[carboxymethyl-(2-oxido-2-oxoethyl)amino]ethyl]amino]acetate
 disodium 2,2'-({2-[bis(carboxymethyl)amino]ethyl}imino)diacetate
 disodium 2,2'-{ethane-1,2-diylbis[(carboxymethyl)imino]}diacetate
 disodium dihydrogen ethylene diamine tetraacetate
 disodium edetate
 disodium EDTA, anhydrous
 disodium ethylenediaminetetraacetate
 edetate disodium
 edetate sodium
 sodium N,N'-ethane-1,2-diylbis(N-(carboxymethyl)glycinate)
Synonyms   Articles   Notes   Search   Top
Synonyms   Articles   Notes   Search   Top
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