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sodium ascorbyl phosphate
sodium L-ascorbic acid 2-phosphate


Name:[(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2H-furan-4-yl] dihydrogen phosphate; sodium
CAS Number: 66170-10-3Picture of molecule3D/inchi
Molecular Weight:325.07359984
Formula:C6 H9 Na3 O9 P
NMR Predictor:Predict (works with chrome or firefox)
Category:food additive and cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Appearance:white to slightly beige powder (est)
Assay: 95.00 to 10.00
Food Chemicals Codex Listed: No
Organoleptic Properties:
Odor Strength:none
Odor Description:at 100.00 %. bland
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antioxidants
Sodium Ascorbyl Phosphate (SAP)
BOC Sciences
For experimental / research use only.
Sodium L-ascorbyl-2-phosphate 98%
Odor: characteristic
Use: Sodium L-ascorbyl-2-phosphate is a stable and a long-lasting vitamin C derivative. It may be used in cell differentiation and tissue engineering applications, such as the repression of dihydrotestosterone-induced dickkopf-1 expression. Sodium L-ascorbyl-2-phosphate may be used in cell differentiation and tissue engineering applications.
Santa Cruz Biotechnology
For experimental / research use only.
vPhospho-L-ascorbic acid trisodium salt ≥95%
Sigma-Aldrich: Sigma
For experimental / research use only.
2-Phospho-L-ascorbic acid trisodium salt ≥95.0% (HPLC)
Spec-Chem Industry
SpecWhite ® SAP(Sodium Ascorbyl Phophate)
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
Category: food additive and cosmetic agents
Recommendation for sodium ascorbyl phosphate usage levels up to:
 not for fragrance use.
Recommendation for sodium ascorbyl phosphate flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the safety and efficacy of vitamin C (ascorbic acid, sodium ascorbate, calcium ascorbate, ascorbyl palmitate, sodium calcium ascorbyl phosphate and sodium ascorbyl phosphate) as a feed additive for all animal species based on a dossier submitted by DSM Nutritional Products Ltd
View page or View pdf
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :54731234
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
[(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2H-furan-4-yl] dihydrogen phosphate; sodium
 [(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2H-furan-4-yl] dihydrogen phosphate; sodium
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):54731234
Pubchem (sid):135325044
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C18341
HMDB (The Human Metabolome Database):Search
EFSA Update of results on the monitoring of furan levels in food:Read Report
EFSA Previous report: Results on the monitoring of furan levels in food:Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food:Read Report
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
[(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2H-furan-4-yl] dihydrogen phosphate; sodium
 sodium L-ascorbic acid 2-phosphate
 sodium L-ascorbyl-2-phosphate
 sodium laevo-ascorbyl-2-phosphate
 trisodium ascorbate-2-phosphate


PubMed:Zinc ascorbate has superoxide dismutase-like activity and in vitro antimicrobial activity against Staphylococcus aureus and Escherichia coli.
PubMed:Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects.
PubMed:Effects of 3% sodium ascorbyl phosphate on the hardness and bond strength of human enamel bleached with 10% carbamide peroxide.
PubMed:Specific effects of single antioxidants in the lipid peroxidation caused by nano-titania used in sunscreen lotions.
PubMed:Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment.
PubMed:Stability of vitamin C derivatives in topical formulations containing lipoic acid, vitamins A and E.
PubMed:Sodium ascorbyl phosphate shows in vitro and in vivo efficacy in the prevention and treatment of acne vulgaris.
PubMed:In vitro evaluation of the effect of electrotreatment on skin permeability.
PubMed:Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics.
PubMed:In vitro antioxidant activities of antioxidant-enriched toothpastes.
PubMed:Investigation of liposomes as carriers of sodium ascorbyl phosphate for cutaneous photoprotection.
PubMed:Bioconvertible vitamin antioxidants improve sunscreen photoprotection against UV-induced reactive oxygen species.
PubMed:Sodium ascorbyl phosphate in topical microemulsions.
PubMed:Stability of ascorbyl palmitate in topical microemulsions.
None found
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