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3-(1-((3,5-dimethyl isoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)-5,5-dimethylimidazolidine-2,4-dione
3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)-5,5-dimethylimidazolidine-2,4-dione

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CAS Number: 1217341-48-4Picture of molecule3D/inchi
FDA UNII: 7S06P17S1V
XlogP3-AA:1.80 (est)
Molecular Weight:409.44611000
Formula:C21 H23 N5 O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:flavor enhancers, bitter taste blockers
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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JECFA Food Flavoring:2162 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)-5,5-dimethylimidazolidine-2,4-dione
FEMA Number:4726 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)-5,5-dimethylimidazolidine-2,4-dione
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):1217341-48-4 ; 3-(1-((3,5-DIMETHYLISOXAZOL-4-YL)METHYL)-1H-PYRAZOL-4-YL)-1-(3- HYDROXYBENZYL)-5,5-DIMETHYLIMIDAZOLIDINE-2,4-DIONE
 
Physical Properties:
Appearance:white solid (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 164.00 to 165.00 °C. @ 760.00 mm Hg
Boiling Point: 626.00 to 627.00 °C. @ 760.00 mm Hg (est)
Flash Point: 631.00 °F. TCC ( 332.90 °C. ) (est)
logP (o/w): 0.570 (est)
Soluble in:
 alcohol
 water, 287.8 mg/L @ 25 °C (est)
Insoluble in:
 water
 
Organoleptic Properties:
Odor Strength:none
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Parchem
3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)-5,5-dimethylimidazolid
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor enhancers, bitter taste blockers
Recommendation for 3-(1-((3,5-dimethyl isoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)-5,5-dimethylimidazolidine-2,4-dione usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 25
Click here to view publication 25
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): 2.0000010.00000
beverages(alcoholic): --
breakfast cereal: 20.0000060.00000
cheese: --
chewing gum: 300.000001200.00000
condiments / relishes: 20.0000060.00000
confectionery froastings: 20.0000060.00000
egg products: --
fats / oils: --
fish products: --
frozen dairy: 20.0000060.00000
fruit ices: 20.0000060.00000
gelatins / puddings: 20.0000060.00000
granulated sugar: --
gravies: --
hard candy: 75.00000300.00000
imitation dairy: 2.0000010.00000
instant coffee / tea: 2.0000010.00000
jams / jellies: --
meat products: --
milk products: 2.0000010.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: 20.0000060.00000
seasonings / flavors: 25.00000100.00000
snack foods: 20.0000060.00000
soft candy: 75.00000300.00000
soups: 2.0000010.00000
sugar substitutes: 2.0000020.00000
sweet sauces: --
 
Safety References:
EPI System: View
AIDS Citations:Search
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Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :53374958
National Institute of Allergy and Infectious Diseases:Data
3-[1-[(3,5-dimethylisoxazol-4-yl)methyl]pyrazol-4-yl]-1-[(3-hydroxyphenyl)methyl]-5,5-dimethyl-imidazolidine-2,4-dione
Chemidplus:1217341484
 
References:
 3-[1-[(3,5-dimethylisoxazol-4-yl)methyl]pyrazol-4-yl]-1-[(3-hydroxyphenyl)methyl]-5,5-dimethyl-imidazolidine-2,4-dione
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):53374958
Pubchem (sid):252300191
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
3-[1-[(3,5-dimethyl-4-isoxazolyl)methyl]-1H-pyrazol-4-yl]-1-[(3-hydroxyphenyl)methyl]-5,5-dimethyl-2,4-imidazolidinedione
3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)-5,5-dimethylimidazolidine-2,4-dione
3-{1-[(3,5-dimethylisoxazol-4-yl)methyl]-1H-pyrazol-4-yl}-1-(3-hydroxybenzyl)-5,5-dimethylimidazolidine-2,4-dione
3-[1-[(3,5-dimethylisoxazol-4-yl)methyl]pyrazol-4-yl]-1-[(3-hydroxyphenyl)methyl]-5,5-dimethyl-imidazolidine-2,4-dione
2,4-imidazolidinedione, 3-[1-[(3,5-dimethyl-4-isoxazolyl)methyl]-1H-pyrazol-4-yl]-1-[(3-hydroxyphenyl)methyl]-5,5-dimethyl-
 
 
Notes:
Chemical Nomenclature provided by BARK Information Services.
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