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Category:information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless solid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 251.31 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 0.003000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 248.00 °F. TCC ( 120.10 °C. ) (est)
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| logP (o/w): | 0.522 (est) |
| Soluble in: |
| | alcohol | | | water, 1.655e+005 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | information only not used for fragrances or flavors |
| Recommendation for (R)-leucic acid usage levels up to: | | | not for fragrance use.
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| Recommendation for (R)-leucic acid flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| dextro-2- | hydroxy-4-methyl pentanoic acid | | (R)-2- | hydroxy-4-methyl valeric acid | | (R)-2- | hydroxy-4-methyl-pentanoic acid | | (2R)-2- | hydroxy-4-methylpentanoic acid | | (R)-2- | hydroxy-4-methylpentanoic acid | | D-2- | hydroxy-4-methylpentanoic acid | | (R)-2- | hydroxy-4-methylpentanoicacid | | (R)-2- | hydroxy-4-methylvaleric acid | | D-2- | hydroxyisocaproate | | (-)-2- | hydroxyisocaproic acid | | (-)-a- | hydroxyisocaproic acid | | (-)-alpha- | hydroxyisocaproic acid | | (R)-alpha- | hydroxyisocaproic acid |
Articles:
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D-Leucic acid is an alpha-hydroxycarboxylic acid present in patients affected with Short-bowel syndrome (an Inborn errors of metabolism, OMIM 175200) (PMID 9766851), and in Maple Syrup Urine Disease (MSUD, an autosomal recessive inherited metabolic disorder of branched-chain amino acid) (PMID 9766851). [HMDB]
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3D/inchi