EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

chromium nicotinate
3-pyridinecarboxylic acid, chromium(2+) salt (2:1)

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Name:chromium(2+); pyridine-3-carboxylate
CAS Number: 148485-19-9Picture of molecule3D/inchi
FDA UNII: Search
Nikkaji Web:J2.877.404D
Molecular Weight:296.20266000
Formula:C12 H8 Cr N2 O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:nutrient supplements, EFSA concludes: use is of safety concern.
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
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Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:grey-purple powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 292.00 to 293.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000836 mmHg @ 25.00 °C. (est)
Flash Point: 267.00 °F. TCC ( 130.70 °C. ) (est)
logP (o/w): 0.147 (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Global Calcium
Chromium Poly Nicotinate -DCP (0.5%)
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
nutrient supplements, EFSA concludes: use is of safety concern.
Recommendation for chromium nicotinate usage levels up to:
 not for fragrance use.
 
Recommendation for chromium nicotinate flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the risks to public health related to the presence of chromium in food and drinking water
View page or View pdf

AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :10334717
National Institute of Allergy and Infectious Diseases:Data
chromium(2+); pyridine-3-carboxylate
 
References:
 chromium(2+); pyridine-3-carboxylate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):10334717
Pubchem (sid):79340411
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 chromium dinicotinate
 chromium polynicotinate
 chromium(2+) dinicotinate
 chromium(2+); pyridine-3-carboxylate
3-pyridinecarboxylic acid, chromium(2+) salt (2:1)
 

Articles:

PubMed:Organoselenium Small Molecules and Chromium(III) Complexes for Intervention in Chronic Low-grade Inflammation and Type 2 Diabetes.
PubMed:Hypoglycemic activity and acute oral toxicity of chromium methionine complexes in mice.
PubMed:Chromium nicotinate has no effect on insulin sensitivity, glycemic control, and lipid profile in subjects with type 2 diabetes.
PubMed:In patients with HIV-infection, chromium supplementation improves insulin resistance and other metabolic abnormalities: a randomized, double-blind, placebo controlled trial.
PubMed:Mass spectrometric and spectroscopic studies of the nutritional supplement chromium(III) nicotinate.
PubMed:Nutrigenomic basis of beneficial effects of chromium(III) on obesity and diabetes.
PubMed:HUM5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate of overweight adults.
PubMed:Alteration of body composition in rats: effect of organic chromium and L-carnitine.
PubMed:Effects of chromium nicotinate on performance, carcase characteristics and blood chemistry of growing turkeys.
PubMed:Comparative induction of oxidative stress in cultured J774A.1 macrophage cells by chromium picolinate and chromium nicotinate.
PubMed:Chromium and exercise training: effect on obese women.
PubMed:Effects of different chromium compounds on blood pressure and lipid peroxidation in spontaneously hypertensive rats.
PubMed:Chromium(III) picolinate produces chromosome damage in Chinese hamster ovary cells.
PubMed:Effects of chromium and guar on sugar-induced hypertension in rats.
PubMed:Chromium picolinate increases membrane fluidity and rate of insulin internalization.
 
Notes:
None found
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