EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

apigenin
5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone

Supplier Sponsors

CAS Number: 520-36-5Picture of molecule3D/inchi
Other(deleted CASRN):461015-54-3
ECHA EINECS - REACH Pre-Reg:208-292-3
FDA UNII: 7V515PI7F6
Beilstein Number:262620
MDL:MFCD00006831
XlogP3:1.70 (est)
Molecular Weight:270.24070000
Formula:C15 H10 O5
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:antioxidants, hair conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 303.00 °C. @ 760.00 mm Hg
Boiling Point: 555.50 °C. @ 760.00 mm Hg (est)
Vapor Pressure:1.010000 mmHg @ 25.00 °C. (est)
Flash Point: 423.00 °F. TCC ( 217.10 °C. ) (est)
logP (o/w): 3.020
Soluble in:
 water, 182.5 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antioxidants
hair conditioning
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Apigenin 98%
BOC Sciences
For experimental / research use only.
Apigenin >98%
Odor: characteristic
Use: Apigenin (4?,5,7-trihydroxyflavone), found in many plants, is a natural product belonging to the flavone class that is the aglycone of several naturally occurring glycosides. Apigenin is a potent P450 inhibitor for CYP2C9 with Ki of 2 mM.
Carbosynth
For experimental / research use only.
Apigenin
Changzhou Longo Chemical
Apigenin
Coompo
For experimental / research use only.
Apigenin from Plants ≥96%
ExtraSynthese
For experimental / research use only.
Apigenin (HPLC) ≥99%
Glentham Life Sciences
Apigenin
Indis NV
For experimental / research use only.
Apigenin
Qingdao Dacon Trading
Apigenin
Santa Cruz Biotechnology
For experimental / research use only.
Apigenin ≥98%
Shaanxi Y-Herb Biotechnology
Bulk Apigenin Monomer Powder Celery Seed Extract Chamomile Supplement
Sigma-Aldrich: Sigma
For experimental / research use only.
Apigenin ≥97% (TLC), from parsley, powder
Skyherb Technologies
Apigenin 98%
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
antioxidants, hair conditioning
Recommendation for apigenin usage levels up to:
 not for fragrance use.
 
Recommendation for apigenin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5280443
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
Chemidplus:0000520365
RTECS:LK9276000 for cas# 520-36-5
 
References:
 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5280443
Pubchem (sid):134976844
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
KEGG (GenomeNet):C01477
HMDB (The Human Metabolome Database):HMDB02124
FooDB:FDB002798
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 anise seed
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 apple heart wood
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 apple wood
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 ashitaba
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 basil plant
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 bean black bean plant
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 bean field bean plant
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 buckwheat
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 cabbage
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 cabbage savoy cabbage
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 carrot fruit
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 carrot seed
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 celery plant
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 celery seed
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 chamomile garden chamomile plant
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 chamomile german chamomile
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 chamomile sweet false chamomile flower
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 cherry sour cherry plant
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 chicory shoot
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 coriander fruit
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 coriander seed
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 date palm stem
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 dill leaf
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 fenugreek plant
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 flax plant
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 garlic bulb
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 ginkgo biloba leaf
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 ginkgo biloba pollen
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 lettuce
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 lippia nodiflora
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 marjoram wild marjoram
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 olive leaf
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 oregano leaf
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 oregano plant
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 parsley plant
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 parsley seed
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 parsley tissue culture
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 peppermint
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 pomegranate leaf
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 rosemary plant
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 sage plant
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 sage shoot
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 savory winter savory plant
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 savory winter savory shoot
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 spearmint leaf
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 tarragon plant
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 tea leaf
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 thyme plant
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 water mint plant
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 wheat seed
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Synonyms:
4H-1-benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)-
4H-1-benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenyl)- (9CI)
5,7-dihydroxy-2-(4-hydroxy-phenyl)-chromen-4-one
5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
2-(p-hydroxyphenyl)-5,7-dihydroxychromone
4',5,7-trihydroxyflavone
 

Articles:

PubMed:Isolation of a flavonoid, apigenin 7-O-glucoside, from Mentha longifolia (L.) Hudson subspecies longifolia and its genotoxic potency.
PubMed:Investigation of testosterone, androstenone, and estradiol metabolism in HepG2 cells and primary culture pig hepatocytes and their effects on 17βHSD7 gene expression.
PubMed:Dietary flavonoids: bioavailability, metabolic effects, and safety.
PubMed:Structural characterisation and antioxidant activity evaluation of phenolic compounds from cold-pressed Perilla frutescens var. arguta seed flour.
PubMed:Effects of the strawberry (Fragaria ananassa) purée elaboration process on non-anthocyanin phenolic composition and antioxidant activity.
PubMed:Protective effects of apigenin against furan-induced toxicity in mice.
PubMed:Phenolic compounds and antioxidant capacity of virgin olive oil.
PubMed:Phenolic Compounds in Fresh and Dried Figs from Cilento (Italy), by Considering Breba Crop and Full Crop, in Comparison to Turkish and Greek Dried Figs.
PubMed:Three-Year Comparative Study of Polyphenol Contents and Antioxidant Capacities in Fruits of Tomato (Lycopersicon esculentum Mill.) Cultivars Grown under Organic and Conventional Conditions.
PubMed:Effects of antioxidants of bamboo leaves and flavonoids on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) formation in chemical model systems.
PubMed:Effects of chemopreventive natural products on non-homologous end-joining DNA double-strand break repair.
PubMed:Stimulation of Osteogenic Activity in Human Osteoblast Cells by Edible Uraria crinita.
PubMed:Protective effect of apigenin against N-nitrosodiethylamine (NDEA)-induced hepatotoxicity in albino rats.
PubMed:Identification and Quantitation of Phenolic Compounds from the Seed and Pomace of Perilla frutescens Using HPLC/PDA and HPLC-ESI/QTOF/MS/MS.
PubMed:Piper betle Leaves: Profiling Phenolic Compounds by HPLC/DAD-ESI/MS(n) and Anti-cholinesterase Activity.
PubMed:Vicenin 2 isolated from Artemisia capillaris exhibited potent anti-glycation properties.
PubMed:Some phenolic compounds of extracts obtained from Origanum species growing in Turkey.
PubMed:Essential Structural Requirements and Additive Effects for Flavonoids to Scavenge Methylglyoxal.
PubMed:HPLC-DAD-ESI/MS(n) analysis of phenolic compounds for quality control of Grindelia robusta Nutt. and bioactivities.
PubMed:Apigenin isolated from Daphne genkwa Siebold et Zucc. inhibits 3T3-L1 preadipocyte differentiation through a modulation of mitotic clonal expansion.
PubMed:The estrogenic effects of apigenin, phloretin and myricetin based on uterotrophic assay in immature Wistar albino rats.
PubMed:Activity-guided isolation of antioxidants from the leaves of Terminalia arjuna.
PubMed:Identification and quantification of phenolic and flavonoid components in straw and seed husk of some rice varieties (Oryza sativa L.) and their antioxidant properties.
PubMed:Minor polar compounds in extra virgin olive oil: correlation between HPLC-DAD-MS and the Folin-Ciocalteu spectrophotometric method.
PubMed:Apigenin has anti-atrophic gastritis and anti-gastric cancer progression effects in Helicobacter pylori-infected Mongolian gerbils.
PubMed:Investigating flavonoids as molecular templates for the design of small-molecule inhibitors of cell signaling.
PubMed:Effects of C-glycosylation on anti-diabetic, anti-Alzheimer's disease and anti-inflammatory potential of apigenin.
PubMed:Absorption, metabolism, and excretion of fermented orange juice (poly)phenols in rats.
PubMed:Structure and function of the peanut panallergen Ara h 8.
PubMed:Characterisation of honeys according to their content of phenolic compounds using high performance liquid chromatography/tandem mass spectrometry.
PubMed:Valorization of artichoke wastewaters by integrated membrane process.
PubMed:Plant polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer chemopreventive action.
PubMed:Flavonoid inhibitory pharmacodynamics on platelet function in physiological environments.
PubMed:Efficacy of PLGA-loaded apigenin nanoparticles in Benzo[a]pyrene and ultraviolet-B induced skin cancer of mice: mitochondria mediated apoptotic signalling cascades.
PubMed:Towards an integrated in vitro strategy for estrogenicity testing.
PubMed:Assay of urinary excretion of polyphenols after ingestion of a cup of mountain tea (Sideritis scardica) measured by HPLC-DAD-ESI-MS/MS.
PubMed:Antioxidant activity of phenolics in leaves of three red pepper (Capsicum annuum) cultivars.
PubMed:Variation in contents of main active components and antioxidant activity in leaves of different pigeon pea cultivars during growth.
PubMed:Altitudinal variation of antioxidant components and capability in Indocalamus latifolius (Keng) McClure leaf.
PubMed:Relationship analysis between flavonoids structure and subcritical water extraction (SWE).
PubMed:Identification of bioactive candidate compounds responsible for oxidative challenge from hydro-ethanolic extract of Moringa oleifera leaves.
PubMed:Antioxidant properties and quantitative UPLC-MS analysis of phenolic compounds from extracts of fenugreek (Trigonella foenum-graecum) seeds and bitter melon (Momordica charantia) fruit.
PubMed:Ethanol extract of the Prunus mume fruits stimulates glucose uptake by regulating PPAR-γ in C2C12 myotubes and ameliorates glucose intolerance and fat accumulation in mice fed a high-fat diet.
PubMed:A new iced tea base herbal beverage with Spergularia rubra extract: metabolic profile stability and in vitro enzyme inhibition.
PubMed:Flavonoid apigenin modified gene expression associated with inflammation and cancer and induced apoptosis in human pancreatic cancer cells through inhibition of GSK-3β/NF-κB signaling cascade.
PubMed:Passiflora manicata (Juss.) aqueous leaf extract protects against reactive oxygen species and protein glycation in vitro and ex vivo models.
PubMed:Interactions between dietary flavonoids apigenin or luteolin and chemotherapeutic drugs to potentiate anti-proliferative effect on human pancreatic cancer cells, in vitro.
PubMed:Metabolic profile and biological activities of Lavandula pedunculata subsp. lusitanica (Chaytor) Franco: studies on the essential oil and polar extracts.
PubMed:Dietary flavonoids fisetin, luteolin and their derived compounds inhibit arginase, a central enzyme in Leishmania (Leishmania) amazonensis infection.
PubMed:Effects of yam peel extract against carbon tetrachloride-induced hepatotoxicity in rats.
PubMed:Chemical quantification and antioxidant assay of four active components in Ficus hirta root using UPLC-PAD-MS fingerprinting combined with cluster analysis.
PubMed:Caecal absorption of vitexin-2-O-xyloside and its aglycone apigenin, in the rat.
PubMed:[Biologically active substances of plant origin. Flavonols and flavones: prevalence, dietary sourses and consumption].
PubMed:Effects of food formulation and thermal processing on flavones in celery and chamomile.
PubMed:Genotoxicity and acute and subchronic toxicity studies of a standardized methanolic extract of Ficus deltoidea leaves.
PubMed:Identification and quantification of leaf surface flavonoids in wild-growing populations of Dracocephalum kotschyi by LC-DAD-ESI-MS.
PubMed:Nutritional and functional potential of Beta vulgaris cicla and rubra.
PubMed:Protective effect of apigenin on mouse acute liver injury induced by acetaminophen is associated with increment of hepatic glutathione reductase activity.
PubMed:An enzyme-linked immunosorbent assay for the measurement of plasma flavonoids in mice fed apigenin-C-glycoside.
PubMed:Effects of blanching on polyphenol stability of innovative paste-like parsley (Petroselinum crispum (Mill.) Nym ex A. W. Hill) and marjoram (Origanum majorana L.) products.
PubMed:Vitexin-2-O-xyloside, raphasatin and (-)-epigallocatechin-3-gallate synergistically affect cell growth and apoptosis of colon cancer cells.
PubMed:Quercetin induces apoptosis via the mitochondrial pathway in KB and KBv200 cells.
PubMed:Compositional characterization of native Peruvian chili peppers (Capsicum spp.).
PubMed:Biological clues to potent DNA-damaging activities in food and flavoring.
PubMed:Isolation of a flavonoid, apigenin 7-O-glucoside, from Mentha longifolia (L.) Hudson subspecies longifolia and its genotoxic potency.
PubMed:Characterization of phenolic compounds, carotenoids, vitamins and antioxidant activities of selected Malaysian wild edible plants.
PubMed:Identification of flavone glucuronide isomers by metal complexation and tandem mass spectrometry: regioselectivity of uridine 5'-diphosphate-glucuronosyltransferase isozymes in the biotransformation of flavones.
PubMed:Flavonoids profiles, antioxidant, acetylcholinesterase inhibition activities of extract from Dryoathyrium boryanum (Willd.) Ching.
PubMed:Influence of drying and cooking process on the phytochemical content, antioxidant and hypoglycaemic properties of two bell Capsicum annum L. cultivars.
PubMed:In vitro anti-inflammatory effect of apigenin in the Helicobacter pylori-infected gastric adenocarcinoma cells.
PubMed:The determination of phenolic profiles of Serbian unifloral honeys using ultra-high-performance liquid chromatography/high resolution accurate mass spectrometry.
PubMed:Estrogen-like activity of aqueous extract from Agrimonia pilosa Ledeb. in MCF-7 cells.
PubMed:Effect of luteolin and apigenin on rosmarinic acid bioavailability in Caco-2 cell monolayers.
PubMed:Apigenin and its impact on gastrointestinal cancers.
PubMed:Influences of glucose on the dietary hydroxyflavonoid-plasma protein interaction.
PubMed:[Determination of plasma protein binding rate of vitexin].
PubMed:Identification, characterisation, and quantification of phenolic compounds in the antioxidant activity-containing fraction from the seeds of Korean perilla (Perilla frutescens) cultivars.
PubMed:Nutrients, phytochemicals and bioactivity of wild Roman chamomile: a comparison between the herb and its preparations.
PubMed:Characterization of apigenin and luteolin derivatives from oil palm (Elaeis guineensis Jacq.) leaf using LC-ESI-MS/MS.
PubMed:Apigenin induces apoptosis through mitochondrial dysfunction in U-2 OS human osteosarcoma cells and inhibits osteosarcoma xenograft tumor growth in vivo.
PubMed:Enzymatic acylation of isoorientin and isovitexin from bamboo-leaf extracts with fatty acids and antiradical activity of the acylated derivatives.
PubMed:C-dideoxyhexosyl flavones from the stems and leaves of Passiflora edulis Sims.
PubMed:Phenolics profiles of olive fruits (Olea europaea L.) and oils from Ayvalık, Domat and Gemlik varieties at different ripening stages.
PubMed:Pharmacokinetic study of luteolin, apigenin, chrysoeriol and diosmetin after oral administration of Flos Chrysanthemi extract in rats.
PubMed:Antioxidant profile of Trifolium pratense L.
PubMed:Measurement of the influence of flavonoids on DNA repair kinetics using the comet assay.
PubMed:Identification of the flavonoids in mungbean (Phaseolus radiatus L.) soup and their antioxidant activities.
PubMed:Influence of harvest year, cultivar and geographical origin on Greek extra virgin olive oils composition: a study by NMR spectroscopy and biometric analysis.
PubMed:Modification of fatty acid, essential oil and phenolic contents of salt-treated sweet marjoram (Origanum majorana L.) according to developmental stage.
PubMed:Influences of four different light-emitting diode lights on flowering and polyphenol variations in the leaves of chrysanthemum (Chrysanthemum morifolium).
PubMed:Isolation and identification of phenolic compounds from the seeds of Perilla frutescens (L.) and their inhibitory activities against α-glucosidase and aldose reductase.
PubMed:A critical evaluation on the reliability of two aluminum chloride chelation methods for quantification of flavonoids.
PubMed:Thymus lotocephalus wild plants and in vitro cultures produce different profiles of phenolic compounds with antioxidant activity.
PubMed:Effects of saline stress on mineral composition, phenolic acids and flavonoids in leaves of artichoke and cardoon genotypes grown in floating system.
PubMed:Flavonoid deactivation of excited state flavins: reaction monitoring by mass spectrometry.
PubMed:Antiallergic effect of Picholine olive oil-in-water emulsions through β-hexosaminidase release inhibition and characterization of their physicochemical properties.
PubMed:Selenium increases chlorogenic acid, chlorophyll and carotenoids of Lycium chinense leaves.
PubMed:Inhibition of proinflammatory biomarkers in THP1 macrophages by polyphenols derived from chamomile, meadowsweet and willow bark.
PubMed:Catechin protects against ketoprofen-induced oxidative damage of the gastric mucosa by up-regulating Nrf2 in vitro and in vivo.
PubMed:Differential suppression of intracellular reactive oxygen species-mediated signaling pathway in vascular endothelial cells by several subclasses of flavonoids.
PubMed:Aqueous extract of Anisomeles indica and its purified compound exerts anti-metastatic activity through inhibition of NF-κB/AP-1-dependent MMP-9 activation in human breast cancer MCF-7 cells.
PubMed:Apigenin decreases cell viability and telomerase activity in human leukemia cell lines.
PubMed:Evaluation of Citrus aurantifolia peel and leaves extracts for their chemical composition, antioxidant and anti-cholinesterase activities.
PubMed:Neuroprotective effects of vitexin, a flavonoid, on pentylenetetrazole-induced seizure in rats.
PubMed:Short photoirradiation induces flavonoid synthesis and increases its production in postharvest vegetables.
PubMed:New highly stable dimeric 3-deoxyanthocyanidin pigments from sorghum bicolor leaf sheath.
PubMed:Evaluation of flavonoids and enterolactone in overnight urine as intake biomarkers of fruits, vegetables and beverages in the Inter99 cohort study using the method of triads.
PubMed:A profile of bioactive compounds of Rumex vesicarius L.
PubMed:Phenolic acid composition and antioxidant properties of Malaysian honeys.
PubMed:Optimization of ultrasonic-assisted enzymatic hydrolysis for the extraction of luteolin and apigenin from celery.
PubMed:Isolation of 3 flavonoids from Mentha longifolia (L.) Hudson subsp. longifolia and determination of their genotoxic potentials by using the E. coli WP2 test system.
PubMed:Inhibition of hepatic uptake transporters by flavonoids.
PubMed:Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities.
PubMed:(-)-Epigallocatechin gallate induces Fas/CD95-mediated apoptosis through inhibiting constitutive and IL-6-induced JAK/STAT3 signaling in head and neck squamous cell carcinoma cells.
PubMed:Release of flavonoids from lupin globulin proteins during digestion in a model system.
PubMed:Optimization of ultrasound assisted extraction of antioxidant compounds from marjoram (Origanum majorana L.) using response surface methodology.
PubMed:Apigenin-induced suicidal erythrocyte death.
PubMed:Antiadipogenic effect of dietary apigenin through activation of AMPK in 3T3-L1 cells.
PubMed:Phenolic compounds in wheat grain cultivars.
PubMed:Comparative evaluation of the antioxidant potential of infant cereals produced from purple wheat and red rice grains and LC-MS analysis of their anthocyanins.
PubMed:Food components with anticaries activity.
PubMed:Chemical Structures of 4-Oxo-Flavonoids in Relation to Inhibition of Oxidized Low-Density Lipoprotein (LDL)-Induced Vascular Endothelial Dysfunction.
PubMed:Vitexin protects against myocardial ischemia/reperfusion injury in Langendorff-perfused rat hearts by attenuating inflammatory response and apoptosis.
PubMed:Flavonoids in tropical citrus species.
PubMed:Antioxidant and antigenotoxic properties of compounds isolated from Marrubium deserti de Noé.
PubMed:[Endothelium-dependent vasorelaxation effects induced by apigenin on the thoracic aorta of rats and its possible mechanism].
PubMed:Dietary apigenin regulates high glucose and hypoxic reoxygenation-induced reductions in apelin expression in human endothelial cells.
PubMed:Liquid chromatography-tandem mass spectrometry analysis allows the simultaneous characterization of C-glycosyl and O-glycosyl flavonoids in stingless bee honeys.
PubMed:Potential interaction of natural dietary bioactive compounds with COX-2.
PubMed:Contribution of Miscanthus x giganteus root exudates to the biostimulation of PAH degradation: an in vitro study.
PubMed:Determination of luteolin and apigenin in celery using ultrasonic-assisted extraction based on aqueous solution of ionic liquid coupled with HPLC quantification.
PubMed:Cytoprotective activity against peroxide-induced oxidative damage and cytotoxicity of flavonoids in C6 rat glioma cells.
PubMed:Effects of genistein, apigenin, quercetin, rutin and astilbin on serum uric acid levels and xanthine oxidase activities in normal and hyperuricemic mice.
PubMed:Evaluation of the effects of the flavonoid apigenin on apoptotic pathway gene expression on the colon cancer cell line (HT29).
PubMed:Evaluation of antioxidant and inhibitory activities for different subclasses flavonoids on enzymes for rheumatoid arthritis.
PubMed:A mechanism of apigenin-induced apoptosis is potentially related to anti-angiogenesis and anti-migration in human hepatocellular carcinoma cells.
PubMed:Antioxidant potential of two red seaweeds from the Brazilian coasts.
PubMed:Apigetrin induces erythroid differentiation of human leukemia cells K562: proteomics approach.
PubMed:Citrus flavonoids luteolin, apigenin, and quercetin inhibit glycogen synthase kinase-3β enzymatic activity by lowering the interaction energy within the binding cavity.
PubMed:[Effects of apigenin on the expression of angiotensin-converting enzyme 2 in kidney in spontaneously hypertensive rats].
PubMed:Approach to the study of C-glycosyl flavones acylated with aliphatic and aromatic acids from Spergularia rubra by high-performance liquid chromatography-photodiode array detection/electrospray ionization multi-stage mass spectrometry.
PubMed:Uncommonly high levels of 3-deoxyanthocyanidins and antioxidant capacity in the leaf sheaths of dye sorghum.
PubMed:Anti-mutagenic and pro-apoptotic effects of apigenin on human chronic lymphocytic leukemia cells.
PubMed:Use of multivariate statistical techniques to optimize the simultaneous separation of 13 phenolic compounds from extra-virgin olive oil by capillary electrophoresis.
PubMed:Antigenotoxicity, cytotoxicity, and apoptosis induction by apigenin, bisabolol, and protocatechuic acid.
PubMed:Apigenin isolated from the seeds of Perilla frutescens britton var crispa (Benth.) inhibits food intake in C57BL/6J mice.
PubMed:Habitual intake of flavonoid subclasses and incident hypertension in adults.
PubMed:[High-performance liquid chromatography for determination of psoralene, bergapten and apigenin in Ficus hirta Vahl].
PubMed:Extraction and identification of three major aldose reductase inhibitors from Artemisia montana.
PubMed:Comparative study of virgin olive oil quality from single varieties cultivated in Chile and Spain.
PubMed:Comparison of the content of bioactive substances and the inhibitory effects against rat plasma oxidation of conventional and organic hot peppers (Capsicum annuum L.).
PubMed:Apigenin inhibits tumor necrosis factor alpha plus high glucose-induced LOX-1 expression in human endothelial cells.
PubMed:Potent modification of inducible CYP1A1 expression by flavonoids.
PubMed:Simultaneous quantification of flavonoids and phenolic acids in plant materials by a newly developed isocratic high-performance liquid chromatography approach.
PubMed:Relative contribution of small and large intestine to deglycosylation and absorption of flavonoids from Chrysanthemun morifolium extract.
PubMed:Influence of the flavonoids apigenin, kaempferol, and quercetin on the function of organic anion transporting polypeptides 1A2 and 2B1.
PubMed:Antioxidant and angiotensin converting enzyme (ACE) inhibitory activities of ethanol extract and pure flavonoids from Adinandra nitida leaves.
PubMed:Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals.
PubMed:Mixture effects of dietary flavonoids on steroid hormone synthesis in the human adrenocortical H295R cell line.
PubMed:Toxicity study of ethanolic extract of Chrysanthemum morifolium in rats.
PubMed:Stroke status evoked adhesion molecule genetic alterations in astrocytes isolated from stroke-prone spontaneously hypertensive rats and the apigenin inhibition of their expression.
PubMed:The dietary flavonoid apigenin blocks phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in breast cell lines.
PubMed:Sap phytochemical compositions of some bananas in Thailand.
PubMed:Chemical composition of Solanum nigrum linn extract and induction of autophagy by leaf water extract and its major flavonoids in AU565 breast cancer cells.
PubMed:Stability of apigeninidin and its methoxylated derivatives in the presence of sulfites.
PubMed:Green, yellow and red emitting CdTe QDs decreased the affinities of apigenin and luteolin for human serum albumin in vitro.
PubMed:Effect of flavonoids on 2'-deoxyguanosine and DNA oxidation caused by singlet molecular oxygen.
PubMed:Effects of plant-derived polyphenols on TNF-alpha and nitric oxide production induced by advanced glycation endproducts.
PubMed:Potential of phenolic antioxidants.
PubMed:Phenolic composition and antioxidant activities of 11 celery cultivars.
PubMed:Total phenolic compounds, flavonoids, and radical scavenging activity of 21 selected tropical plants.
PubMed:Flavone C-glycosides from seeds of fenugreek, Trigonella foenum-graecum L.
PubMed:Depsides and other polar constituents from Origanum dictamnus L. and their in vitro antimicrobial activity in clinical strains.
PubMed:Antioxidant activity and phenolic profile of pistachio (Pistacia vera L., variety Bronte) seeds and skins.
PubMed:Secondary plant substances in various extracts of the leaves, fruits, stem and bark of Caraipa densifolia Mart.
PubMed:The natural flavonoid apigenin suppresses Th1- and Th2-related chemokine production by human monocyte THP-1 cells through mitogen-activated protein kinase pathways.
PubMed:[Studies on the lowering blood sugar substances from agrimony].
PubMed:Lipid-lowering and antioxidant effects of an ethyl acetate extract of fenugreek seeds in high-cholesterol-fed rats.
PubMed:Influence of the target molecule on the oxygen radical absorbance capacity index: a comparison between alizarin red- and fluorescein-based methodologies.
PubMed:Cytotoxicity of apigenin on leukemia cell lines: implications for prevention and therapy.
PubMed:Caffeoylquinic acids and flavonoids in the immature inflorescence of globe artichoke, wild cardoon, and cultivated cardoon.
PubMed:Anticancer effects of Alpinia pricei Hayata roots.
PubMed:Metabolomics analysis reveals the compositional differences of shade grown tea (Camellia sinensis L.).
PubMed:Greater apparent absorption of flavonoids is associated with lesser human fecal flavonoid disappearance rates.
PubMed:Improved method for identifying and quantifying olive oil phenolic compounds and their metabolites in human plasma by microelution solid-phase extraction plate and liquid chromatography-tandem mass spectrometry.
PubMed:Tentative characterization of novel phenolic compounds in extra virgin olive oils by rapid-resolution liquid chromatography coupled with mass spectrometry.
PubMed:Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity.
PubMed:Inhibitory effect of flavonoids on 26S proteasome activity.
PubMed:Plantain (Plantago L.) species as novel sources of flavonoid antioxidants.
PubMed:The relationship between fasting plasma concentrations of selected flavonoids and their ordinary dietary intake.
PubMed:Flavonoid composition and antioxidant activity of tree peony (Paeonia section moutan) yellow flowers.
PubMed:Purification and characterization of an olive fruit beta-glucosidase involved in the biosynthesis of virgin olive oil phenolics.
PubMed:Anti-inflammatory effects of the roots of Alpinia pricei Hayata and its phenolic compounds.
PubMed:Antiproliferative effects of honey and of its polyphenols: a review.
PubMed:Antioxidant activity of commercial wild rice and identification of flavonoid compounds in active fractions.
PubMed:Effect of processing on the flavonoid content and antioxidant capacity of Citrus hystrix leaf.
PubMed:Bioavailability of C-linked dihydrochalcone and flavanone glucosides in humans following ingestion of unfermented and fermented rooibos teas.
PubMed:Apigenin and related compounds stimulate adult neurogenesis. Mars, Inc., the Salk Institute for Biological Studies: WO2008147483.
PubMed:Linalool decreases HepG2 viability by inhibiting mitochondrial complexes I and II, increasing reactive oxygen species and decreasing ATP and GSH levels.
PubMed:Cytotoxicity of flavones and flavonols to a human esophageal squamous cell carcinoma cell line (KYSE-510) by induction of G2/M arrest and apoptosis.
PubMed:Antioxidant activities of extracts and main components of Pigeonpea [Cajanus cajan (L.) Millsp.] leaves.
PubMed:Comparison of flavonoids and isoflavonoids as antioxidants.
PubMed:[Effect of high dose apigenin on antioxidase activity and DNA damage in rats].
PubMed:Dietary flavonoid apigenin inhibits high glucose and tumor necrosis factor alpha-induced adhesion molecule expression in human endothelial cells.
PubMed:Dietary intake of selected flavonols, flavones, and flavonoid-rich foods and risk of cancer in middle-aged and older women.
PubMed:Antigenotoxic effect of apigenin against mitomycin C induced genotoxic damage in mice bone marrow cells.
PubMed:Correlation between antiangiogenic activity and antioxidant activity of various components from propolis.
PubMed:Oregano: a source for peroxisome proliferator-activated receptor gamma antagonists.
PubMed:Analysis of flavonoids in propolis and Ginkgo biloba by micellar electrokinetic capillary chromatography.
PubMed:Dietary apigenin attenuates the development of atopic dermatitis-like skin lesions in NC/Nga mice.
PubMed:Phenolic compounds and chromatographic profiles of pear skins (Pyrus spp.).
PubMed:Accurate assessment of the bioactivities of redox-active polyphenolics in cell culture.
PubMed:Solid-liquid transfer of biophenols from olive leaves for the enrichment of edible oils by a dynamic ultrasound-assisted approach.
PubMed:[Studies on chemical constituents of Saussurea laniceps].
PubMed:Mediterranean diet and cardioprotection: wild artichoke inhibits metalloproteinase 9.
PubMed:Update on uses and properties of citrus flavonoids: new findings in anticancer, cardiovascular, and anti-inflammatory activity.
PubMed:Dietary flavonoid sources in Australian adults.
PubMed:Determination of total soy isoflavones in dietary supplements, supplement ingredients, and soy foods by high-performance liquid chromatography with ultraviolet detection: collaborative study.
PubMed:Apigenin inhibits platelet adhesion and thrombus formation and synergizes with aspirin in the suppression of the arachidonic acid pathway.
PubMed:Antioxidative activity of the flower of Torenia fournieri.
PubMed:Flavones and flavonols exert cytotoxic effects on a human oesophageal adenocarcinoma cell line (OE33) by causing G2/M arrest and inducing apoptosis.
PubMed:Liquid-liquid extraction for the enrichment of edible oils with phenols from olive leaf extracts.
PubMed:Deconjugation and degradation of flavonol glycosides by pig cecal microbiota characterized by Fluorescence in situ hybridization (FISH).
PubMed:HPLC-PDA-MS and NMR characterization of C-glycosyl flavones in a hydroalcoholic extract of Citrus aurantifolia leaves with antiplatelet activity.
PubMed:Comparative antioxidant activity and HPLC profiles of some selected Korean thistles.
PubMed:Differential effects of dietary flavonoids on reactive oxygen and nitrogen species generation and changes in antioxidant enzyme expression induced by proinflammatory cytokines in Chang Liver cells.
PubMed:Effects of apigenin, lycopene and astaxanthin on 7 beta-hydroxycholesterol-induced apoptosis and Akt phosphorylation in U937 cells.
PubMed:Plant-derived polyphenols attenuate lipopolysaccharide-induced nitric oxide and tumour necrosis factor production in murine microglia and macrophages.
PubMed:HPLC-DAD-ESI-MS analysis of the constituents of aqueous preparations of verbena and lemon verbena and evaluation of the antioxidant activity.
PubMed:Estrogenic activities of isoflavones and flavones and their structure-activity relationships.
PubMed:[Effects of flavonoids with different structures on proliferation of leukemia cell line HL-60].
PubMed:Oxidative DNA damage preventive activity and antioxidant potential of Stevia rebaudiana (Bertoni) Bertoni, a natural sweetener.
PubMed:New C-deoxyhexosyl flavones and antioxidant properties of Passiflora edulis leaf extract.
PubMed:Cell cycle control as a basis for cancer chemoprevention through dietary agents.
PubMed:Antiproliferative and apoptotic effects of chamomile extract in various human cancer cells.
PubMed:Effects of flavonoid mixtures on the transport of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) through Caco-2 monolayers: an in vitro and kinetic modeling approach to predict the combined effects on transporter inhibition.
PubMed:Phytochemical profiling and phase II enzyme-inducing properties of Thunbergia laurifolia Lindl. (RC) extracts.
PubMed:Application of capillary electrophoresis to study phenolic profiles of honeybee-collected pollen.
PubMed:[Thyroid diseases in sub-Saharan Africa].
PubMed:Dietary flavonoid apigenin is a potential inducer of intracellular oxidative stress: the role in the interruptive apoptotic signal.
PubMed:Influence of food polyphenols on aryl hydrocarbon receptor-signaling pathway estimated by in vitro bioassay.
PubMed:Identification and quantification of flavonoids of Mexican oregano (Lippia graveolens) by LC-DAD-ESI/MS analysis.
PubMed:[Studies on chemical constituent and quantitative determination of Mallotus apelta].
PubMed:Determination of flavonoid aglycones in several food samples by mixed micellar electrokinetic chromatography.
PubMed:Ultrasensitive cell-based bioassay for the measurement of global estrogenic activity of flavonoid mixtures revealing additive, restrictive, and enhanced actions in binary and higher order combinations.
PubMed:Impact of adenomatous polyposis coli (APC) tumor supressor gene in human colon cancer cell lines on cell cycle arrest by apigenin.
PubMed:Antihyperglycemic effect of Cephalotaxus sinensis leaves and GLUT-4 translocation facilitating activity of its flavonoid constituents.
PubMed:Dietary flavones suppresses IgE and Th2 cytokines in OVA-immunized BALB/c mice.
PubMed:Flavonoid glycosides are not transported by the human Na+/glucose transporter when expressed in Xenopus laevis oocytes, but effectively inhibit electrogenic glucose uptake.
PubMed:Keratinocyte proliferation, differentiation, and apoptosis--differential mechanisms of regulation by curcumin, EGCG and apigenin.
PubMed:(Anti)estrogenic effects of phytochemicals on human primary mammary fibroblasts, MCF-7 cells and their co-culture.
PubMed:The effects of essential oils and aqueous tea infusions of oregano (Origanum vulgare L. spp. hirtum), thyme (Thymus vulgaris L.) and wild thyme (Thymus serpyllum L.) on the copper-induced oxidation of human low-density lipoproteins.
PubMed:Apigenin increases osteoblastic differentiation and inhibits tumor necrosis factor-alpha-induced production of interleukin-6 and nitric oxide in osteoblastic MC3T3-E1 cells.
PubMed:Static-dynamic superheated liquid extraction of hydroxytyrosol and other biophenols from alperujo (a semisolid residue of the olive oil industry).
PubMed:Flavonoids from barrel medic (Medicago truncatula) aerial parts.
PubMed:Attenuation of monocyte adhesion and oxidised LDL uptake in luteolin-treated human endothelial cells exposed to oxidised LDL.
PubMed:Flavonoids alter P-gp expression in intestinal epithelial cells in vitro and in vivo.
PubMed:Polyphenol content and antioxidative activity in some species of freshly consumed salads.
PubMed:Comparison of analytical methodologies based on 1h and 31p NMR spectroscopy with conventional methods of analysis for the determination of some olive oil constituents.
PubMed:Detection and quantification of glycosylated flavonoid malonates in celery, Chinese celery, and celery seed by LC-DAD-ESI/MS.
PubMed:Absorption and excretion of luteolin and apigenin in rats after oral administration of Chrysanthemum morifolium extract.
PubMed:Quantitative analysis of anticancer 3-deoxyanthocyanidins in infected sorghum seedlings.
PubMed:Estrogenic activity of the chlorinated derivatives of estrogens and flavonoids using a GFP expression system.
PubMed:Flavonoid content of U.S. fruits, vegetables, and nuts.
PubMed:Age-related variations in flavonoid intake and sources in the Australian population.
PubMed:Flavonoids modulate monocarboxylate transporter-1-mediated transport of gamma-hydroxybutyrate in vitro and in vivo.
PubMed:Quantitative determination of phenolic compounds in artichoke-based dietary supplements and pharmaceuticals by high-performance liquid chromatography.
PubMed:Gas-phase ligation of Fe+ and Cu+ ions with some flavonoids.
PubMed:Prenylation enhances cytotoxicity of apigenin and liquiritigenin in rat H4IIE hepatoma and C6 glioma cells.
PubMed:Pistachio skin phenolics are destroyed by bleaching resulting in reduced antioxidative capacities.
PubMed:An accurate and reproducible method for the quantitative analysis of isoflavones and their metabolites in rat plasma using liquid chromatography/mass spectrometry combined with photodiode array detection.
PubMed:Effect of dietary apigenin on colonic ornithine decarboxylase activity, aberrant crypt foci formation, and tumorigenesis in different experimental models.
PubMed:Rumex induratus leaves: interesting dietary source of potential bioactive compounds.
PubMed:Polar constituents from the aerial parts of Origanum vulgare L. Ssp. hirtum growing wild in Greece.
PubMed:Dietary apigenin suppresses IgE and inflammatory cytokines production in C57BL/6N mice.
PubMed:Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1.
PubMed:Antioxidant constituents in the fruits of Luffa cylindrica (L.) Roem.
PubMed:Antiproliferative activities of parthenolide and golden feverfew extract against three human cancer cell lines.
PubMed:The flavonoid glycosides and procyanidin composition of Deglet Noor dates (Phoenix dactylifera).
PubMed:Determination of flavonoids in Portulaca oleracea L. by capillary electrophoresis with electrochemical detection.
PubMed:Bioavailability of apigenin from apiin-rich parsley in humans.
PubMed:Wild artichoke prevents the age-associated loss of vasomotor function.
PubMed:Flavone C-glycosides from leaves of Oxalis triangularis.
PubMed:Use of the pig caecum model to mimic the human intestinal metabolism of hispidulin and related compounds.
PubMed:Phytochemical phenolics in organically grown vegetables.
PubMed:Apigenin induces apoptosis in Hep G2 cells: possible role of TNF-alpha and IFN-gamma.
PubMed:Up-regulation of insulin-like growth factor binding protein-3 by apigenin leads to growth inhibition and apoptosis of 22Rv1 xenograft in athymic nude mice.
PubMed:Determination of phenolic compounds in Perilla frutescens L. by capillary electrophoresis with electrochemical detection.
PubMed:Structural characterization of a flavonoid-inducible Pseudomonas aeruginosa A-band-like O antigen of Rhizobium sp. strain NGR234, required for the formation of nitrogen-fixing nodules.
PubMed:Isovitexin suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kappa B in mouse macrophages.
PubMed:Formation and inhibition of genotoxic malonaldehyde from DNA oxidation controlled with EDTA.
PubMed:Phytotoxic activity of bibenzyl derivatives from the orchid Epidendrum rigidum.
PubMed:Inhibitory effects of apigenin on the growth of gastric carcinoma SGC-7901 cells.
PubMed:Isolation and structure elucidation of phenolic antioxidants from Tamarind (Tamarindus indica L.) seeds and pericarp.
PubMed:Sensory-guided decomposition of roasted cocoa nibs (Theobroma cacao) and structure determination of taste-active polyphenols.
PubMed:Oral flavonoids delay recovery from experimental autoimmune encephalomyelitis in SJL mice.
PubMed:Effect of the conservation procedure on the contents of phenolic compounds and organic acids in chanterelle (Cantharellus cibarius) mushroom.
PubMed:Separation and identification of phenolic compounds in olive oil by coupling high-performance liquid chromatography with postcolumn solid-phase extraction to nuclear magnetic resonance spectroscopy (LC-SPE-NMR).
PubMed:Human gut microbial degradation of flavonoids: structure-function relationships.
PubMed:Phenylpropanoid glycosides from Tynanthus panurensis: characterization and LC-MS quantitative analysis.
PubMed:Evaluation of the effect of germination on phenolic compounds and antioxidant activities in sorghum varieties.
PubMed:Antioxidant activity of citrus limonoids, flavonoids, and coumarins.
PubMed:Flavones suppress the expression of the high-affinity IgE receptor FcepsilonRI in human basophilic KU812 cells.
PubMed:Antioxidant activity of the main phenolic compounds isolated from hot pepper fruit (Capsicum annuum L).
PubMed:RP-HPLC analysis of the phenolic compounds of plant extracts. investigation of their antioxidant capacity and antimicrobial activity.
PubMed:Phenolic compounds from the leaf extract of artichoke (Cynara scolymus L.) and their antimicrobial activities.
PubMed:Analysis of minor components in olive oil.
PubMed:Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity.
PubMed:Study of flavonoids of Sechium edule (Jacq) Swartz (Cucurbitaceae) different edible organs by liquid chromatography photodiode array mass spectrometry.
PubMed:Inhibition of malonaldehyde formation in oxidized calf thymus DNA with synthetic and natural antioxidants.
PubMed:The effect of two dietary and a synthetic phytoestrogen on transepithelial calcium transport in human intestinal-like Caco-2 cells.
PubMed:Combined effects of multiple flavonoids on breast cancer resistance protein (ABCG2)-mediated transport.
PubMed:The flavone hispidulin, a benzodiazepine receptor ligand with positive allosteric properties, traverses the blood-brain barrier and exhibits anticonvulsive effects.
PubMed:Flavonoids promote cell migration in nontumorigenic colon epithelial cells differing in Apc genotype: implications of matrix metalloproteinase activity.
PubMed:Effect of flavonoids and vitamin E on cyclooxygenase-2 (COX-2) transcription.
PubMed:Antioxidant properties of raw and processed cabbages.
PubMed:Identification and quantification of caffeoylquinic acids and flavonoids from artichoke (Cynara scolymus L.) heads, juice, and pomace by HPLC-DAD-ESI/MS(n).
PubMed:Individual and interactive effects of apigenin analogs on G2/M cell-cycle arrest in human colon carcinoma cell lines.
PubMed:Identification of the astringent taste compounds in black tea infusions by combining instrumental analysis and human bioresponse.
PubMed:Flavonoids from Argentine Tagetes (Asteraceae) with antimicrobial activity.
PubMed:Kinetic study of flavonoid reactions with stable radicals.
PubMed:Flavones mitigate tumor necrosis factor-alpha-induced adhesion molecule upregulation in cultured human endothelial cells: role of nuclear factor-kappa B.
PubMed:Steroid activities comparison of natural and food wrap compounds in human breast cancer cell lines.
PubMed:Dietary compounds prevent oxidative damage and nitric oxide production by cells involved in demyelinating disease.
PubMed:Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cells.
PubMed:Effect of the rootstock and interstock grafted in lemon tree (Citrus limon (L.) Burm.) on the flavonoid content of lemon juice.
PubMed:Effects of plant flavonoids on fecundity, survival, and feeding of the Formosan subterranean termite.
PubMed:Inhibitory effects of several flavonoids on E-selectin expression on human umbilical vein endothelial cells stimulated by tumor necrosis factor-alpha.
PubMed:Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context.
PubMed:Antioxidant effect of phenolic compounds, alpha-tocopherol, and other minor components in virgin olive oil.
PubMed:Phenolic constituents and antioxidant properties of Xanthosoma violaceum leaves.
PubMed:Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb(1) (ginseng) and parthenolide (feverfew).
PubMed:Estrogenic effects of food wrap packaging xenoestrogens and flavonoids in female Wistar rats: a comparative study.
PubMed:Herbivore-induced responses in alfalfa (Medicago sativa).
PubMed:Isolation, structure elucidation and antioxidant potential of the major phenolic and flavonoid compounds in brined olive drupes.
PubMed:Constituents of sage (Salvia officinalis) with in vitro affinity to human brain benzodiazepine receptor.
PubMed:Kinetic and stoichiometric assessment of the antioxidant activity of flavonoids by electron spin resonance spectroscopy.
PubMed:Analysis of antioxidative phenolic compounds in artichoke (Cynara scolymus L.).
PubMed:Flavonol and flavone intakes in US health professionals.
PubMed:Antioxidant activities and phenolic composition of extracts from Greek oregano, Greek sage, and summer savory.
PubMed:Effect of processing techniques at industrial scale on orange juice antioxidant and beneficial health compounds.
PubMed:Antioxidative flavonoids from leaves of Carthamus tinctorius.
PubMed:Oxidation of quercetin by salivary components. Quercetin-dependent reduction of salivary nitrite under acidic conditions producing nitric oxide.
PubMed:In vitro investigation of cytochrome P450-mediated metabolism of dietary flavonoids.
PubMed:Flavonoid (myricetin, quercetin, kaempferol, luteolin, and apigenin) content of edible tropical plants.
PubMed:In vitro availability of flavonoids and other phenolics in orange juice.
PubMed:Alfalfa (Medicago sativa L.) flavonoids. 1. Apigenin and luteolin glycosides from aerial parts.
PubMed:Suppressive effects of flavonoids on dioxin toxicity.
PubMed:Flavonoids and phenolic acids of sage: influence of some agricultural factors.
PubMed:Antimutagens in gaiyou (Artemisia argyi levl. et vant.).
PubMed:Estrogenic activity of flavonoids in mice. The importance of estrogen receptor distribution, metabolism and bioavailability.
PubMed:Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines.
PubMed:Thyroid ultrasound is the best prevalence indicator for assessment of iodine deficiency disorders: a study in rural/tribal schoolchildren from Gujarat (Western India).
PubMed:Antioxidant and cyclooxygenase inhibitory phenolic compounds from Ocimum sanctum Linn.
PubMed:Differential effects of dietary flavonoids on drug metabolizing and antioxidant enzymes in female rat.
PubMed:Effect of parsley (Petroselinum crispum) intake on urinary apigenin excretion, blood antioxidant enzymes and biomarkers for oxidative stress in human subjects.
PubMed:Phenolic compounds in Spanish olive oils.
PubMed:Purification of cytosolic beta-glucosidase from pig liver and its reactivity towards flavonoid glycosides.
PubMed:Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity.
PubMed:Effects of phytoestrogens on DNA synthesis in MCF-7 cells in the presence of estradiol or growth factors.
PubMed:Column-switching high-performance liquid chromatographic assay for determination of apigenin and acacetin in human urine with ultraviolet absorbance detection.
PubMed:In vitro attenuation of nitric oxide production in C6 astrocyte cell culture by various dietary compounds.
PubMed:Flavonoid deactivation of ferrylmyoglobin in relation to ease of oxidation as determined by cyclic voltammetry.
PubMed:Detection of weak estrogenic flavonoids using a recombinant yeast strain and a modified MCF7 cell proliferation assay.
PubMed:In vitro biotransformation of flavonoids by rat liver microsomes.
PubMed:Phytoestrogen concentration determines effects on DNA synthesis in human breast cancer cells.
PubMed:Antimutagenic effect of plant flavonoids in the Salmonella assay system.
PubMed:Determination of flavone C-glycosides in tea.
PubMed:Antimutagenic effects of flavonoids, chalcones and structurally related compounds on the activity of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and other heterocyclic amine mutagens from cooked food.
PubMed:Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands.
PubMed:Antithyroid and goitrogenic effects of millet: role of C-glycosylflavones.
 
Notes:
5,7,4'-trihydroxy-flavone, one of the flavones. Flavone found in a wide variety of foodstuffs; buckwheat, cabbage, celeriac, celery, lettuce, oregano, parsley, peppermint, perilla, pummelo juice, thyme, sweet potatoes, green tea and wild carrot [DFC]
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