diatomaceous earth
kieselguhr
 
Notes:
a form of silicon dioxide composed of skeletons of prehistoric aquatic plants which is used for its absorption quality, taking up 1.5-4 times its weight in water. the microscopic sharp edges are useful for insect control but can also be an inhalation hazard. it has been used in baked goods and animal feed. kieselguhr is german for flint + earthy sediment. tsca definition 2008: a soft siliceous solid composed of skeletons of small prehistoric aquatic plants. contains primarily silica. Occurs in food as a substance migrating from paper and paperboard products used in packaging A soft siliceous solid composed of skeletons of small prehistoric aquatic plants. Contains primarily silica. (SciFinder)
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CAS Number: 61790-53-2 
Other: 11139-66-5
FDA UNII: 2RF6EJ0M85
Nikkaji Web: J43.598H
MDL: MFCD00132803
Formula: unspecified
Category: multipurpose additives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
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EU Patents: Search
IBM Patents: Obtain
Pubchem Patents: Search
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NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
1979 Diatomaceous earth (filter aid) View-review
GRN 87 Composite filtration media (diatomaceous earth and perlite) View-notice PDF
JECFA Food Additive: Diatomaceous Earth
DG SANTE Food Contact Materials: diatomaceous earth
FDA Mainterm: DIATOMACEOUS EARTH
FDA Regulation:
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1680 Polyurethane resins.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2260 Filters, resin-bonded.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2410 Phenolic resins in molded articles.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart D--Certain Adjuvants and Production Aids
Sec. 178.3297 Colorants for polymers.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 182.90 Substances migrating to food from paper and paperboard products.


FDA PART 573 -- FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS
Subpart B--Food Additive Listing
Sec. 573.340 Diatomaceous earth.
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Physical Properties:
Appearance: white powder (est)
Food Chemicals Codex Listed: No
Insoluble in:
 paraffin oil
 water
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Organoleptic Properties:
Odor Description:
odorless
Taste Description:
tasteless
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: abrasives
anticaking agents
bulking agents
opacifying agents
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Suppliers:
Kraft Chemical
Diatomaceous Earth
Santa Cruz Biotechnology
For experimental / research use only.
Diatomaceous earth non-washed
Sigma-Aldrich
For experimental / research use only.
Diatomaceous earth non-washed ∼90% SiO2 basis, powder
Silver Fern Chemical
Diatomaceous Earth
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: multipurpose additives
Recommendation for diatomaceous earth usage levels up to:
 not for fragrance use.
 
Recommendation for diatomaceous earth flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Conclusion on the peer review of the pesticide risk assessment of the active substance kieselgur (diatomaceous earth)
View page or View pdf
Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf
Outcome of the consultation with Member States, the applicant and EFSA on the pesticide risk assessment for kieselgur (diatomaceous earth) in light of confirmatory data
View page or View pdf
NIOSH International Chemical Safety Cards: search
Cancer Citations: Search
Toxicology Citations: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 61790-53-2
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 24261
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 dioxosilane
Chemidplus: 0061790532
RTECS: 61790-53-2
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References:
 dioxosilane
Pubchem (cid): 24261
Pubchem (sid): 135290630
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Other Information:
FDA Everything Added to Food in the United States (EAFUS): View
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): D05839
HMDB (The Human Metabolome Database): HMDB35897
FooDB: FDB014819
Export Tariff Code: 2512.00.0000
Haz-Map: View
Household Products: Search
VCF-Online: VCF Volatile Compounds in Food
Wikipedia: View
RSC Learn Chemistry: View
Formulations/Preparations:
•usepaopp pesticide code 072605; 46 active products contain amorphous silicon dioxide, celite, diatomaceous earth, or silicon dioxide. many of these products contain other additional active pesticide ingredients. trade names: chemsico insecticide de; crop guard; diafil 610; diasource diatomaceous earth crawling insect killer; diasource diatomaceous earth grain storage insecticide; diatect d-20; diatect insecticide v; diatect multipurpose insecticide; diatect multipurpose insecticide ii; diatect pet powder; diatom dust insect powder; diatomic earth; dry pyrocide insecticide; dryacide; eaton's answer ii; eaton's k.i.o. (kills insects only) system; enforcer insecticide powder; flea away; flea scare; garden-ville diatomaceous earth; grapple flea powder; harper valley diatomaceous earth; hi-yield crawling insect control; insecolo; insect dust; insect-aside p.p.d. multipurpose insecticide; insectaside d. e.; insectigone; insecto; melocide de-200; melocide de-100; organic resources multipurpose insecticide; perma guard garden and plant insecticide d-21; perma-guard commercial insecticide d-20; perma-guard grain or seed storage insecticide d-10; perma-guard household insecticide d-20; perma-guard kleen bin d-20; perma-guard pet and animal insecticide d-20; powdered insecticide; protect-it; pyrocide insecticide ii; shellshock insecticide; southwest select diatomaceous earth; speer dry insecticide; the graden guy diatomaceous earth; whitmire pt-239 tri-die insecticide •perma-guard grain or seed storage insecticide dust d-10--80% active ingredient. •wettable powder •wessalon is spray-dried precipitated silica; 98-99.5% silicon dioxide, amorphous; particle sizes 1-100 microns. other name: sipernat. •cab-o-sil* is 99.8% silicon dioxide, amorphous. a white powder, ultrafine particle size (.014 microns). other names: colloidal silicon dioxide, amorphous silica. water dispersible. combinations: synergistic effect with other thickeners. •technical grade, fcc grade, fda grade, high-purity, 0.03 micron grade, ground and whole grain sand grades, powder, pellets, fumed silica (hydrophobic), aqueous slurries of colloidal fumed silica, ground silica, silica flour, silica gel. a range of grades and mesh sizes. •diatomaceous earth (88% silica) composed of skeletons of small prehistoric aquatic plants related to algae (diatoms).
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 found in nature
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Synonyms:
 aquafil N 81
 armsorb gkhi
 calofrig Fj
 celatom
 celite
 chromaton
 chromatron N super
 chromosorb G
 diatomite
 fossil flour
 kieselguhr
 silica diatomaceous
 siliceous earth
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Articles:
PubMed: The insecticidal effect of diatomaceous earth against adults and nymphs of Blattella germanica.
PubMed: Anionic surfactant micelle-mediated extraction coupled with dispersive magnetic microextraction for the determination of phthalate esters.
PubMed: Optimisation of a sample preparation method for the determination of fumonisin B(1) in rice.
PubMed: Production and characterization of crude and refined oils obtained from the co-products of Nile tilapia and hybrid sorubim processing.
PubMed: Horizontal transfer of diatomaceous earth and botanical insecticides in the common bed bug, Cimex lectularius L.; hemiptera: cimicidae.
PubMed: Simultaneous determination of total fatty acid esters of chloropropanols in edible oils by gas chromatography-mass spectrometry with solid-supported liquid-liquid extraction.
PubMed: Validation (in-house and collaboratory) of the quantification method for ethyl carbamate in alcoholic beverages and soy sauce by GC-MS.
PubMed: Micro-nanopores fabricated by high-energy electron beam irradiation: suitable structure for controlling pesticide loss.
PubMed: A rapid method to determine sterol, erythrodiol, and uvaol concentrations in olive oil.
PubMed: Purification of recombinant EGFP by fusion with L2 (252-273) from ribosomal protein L2 using magnetic particles.
PubMed: Characterization of the diatomite binding domain in the ribosomal protein L2 from E. coli and functions as an affinity tag.
PubMed: Determination of chlorophylls in Taraxacum formosanum by high-performance liquid chromatography-diode array detection-mass spectrometry and preparation by column chromatography.
PubMed: Determination of carotenoids in Taraxacum formosanum by HPLC-DAD-APCI-MS and preparation by column chromatography.
PubMed: Immobilization of glucosyltransferase from Erwinia sp. using two different techniques.
PubMed: Matrix solid phase dispersion extraction of ginsenosides in the leaves of Panax ginseng C.M. Mey.
PubMed: Determination of chloropropanols in foods by one-step extraction and derivatization using pressurized liquid extraction and gas chromatography-mass spectrometry.
PubMed: [Study on rapid analysis method of pesticide contamination in processed foods by GC-MS and GC-FPD].
PubMed: Determination of perfluorinated compounds in mollusks by matrix solid-phase dispersion and liquid chromatography-tandem mass spectrometry.
PubMed: Effect of diatomaceous earth on parasite load, egg production, and egg quality of free-range organic laying hens.
PubMed: Preparation of carotenoids and chlorophylls from Gynostemma pentaphyllum (Thunb.) Makino and their antiproliferation effect on hepatoma cell.
PubMed: Capillary liquid chromatography with diode array and mass spectrometry detection for heterocyclic aromatic amine determination in ready-to-eat food treated with electron-beam irradiation.
PubMed: [Analysis of acephate, methamidophos and omethoate in animal and fishery products, and honey by LC-MS].
PubMed: Multi-residue method for the determination of organochlorine pesticides in fish feed based on a cleanup approach followed by gas chromatography-triple quadrupole tandem mass spectrometry.
PubMed: Silicon in beer and brewing.
PubMed: Acaricidal effect of different diatomaceous earth formulations against Tyrophagus putrescentiae (Astigmata: Acaridae) on stored wheat.
PubMed: Determination of benzoylurea insecticides in food by pressurized liquid extraction and LC-MS.
PubMed: Short communication: Evaluation of supercritical fluid extraction aids for optimum extraction of nonpolar lipids from buttermilk powder.
PubMed: Detection and isolation of antiatherogenic and antioxidant substances present in olive mill wastes by a novel filtration system.
PubMed: Optimized HPLC method for analysis of polar and nonpolar heterocyclic amines in cooked meat products.
PubMed: Matrix solid-phase dispersion as a sample pretreatment for the speciation of arsenic in seafood products.
PubMed: Evaluation of natural diatomaceous earth deposits from south-eastern Europe for stored-grain protection: the effect of particle size.
PubMed: Development of an analytical scheme for the determination of pyrethroid pesticides in composite diet samples.
PubMed: [Factors affecting Diatomaceous earth effectiveness in the control of Alphitobius diaperinus (Panzer) (Coleoptera: Tenebrionidae) adults].
PubMed: Determination of neonicotinoid insecticides residues in bovine milk samples by solid-phase extraction clean-up and liquid chromatography with diode-array detection.
PubMed: Esterification and hydrolytic activities of Candida rugosa lipase isoform 1 (LIP1) immobilized on celite 545, duolite A7, and sephadex G-25.
PubMed: Removal of basic dye (methylene blue) from wastewaters utilizing beer brewery waste.
PubMed: Use of solid-supported liquid-liquid extraction in the analysis of polyphenols in wine.
PubMed: On-capillary sample cleanup method for the electrophoretic determination of carbohydrates in juice samples.
PubMed: Effect of fining and filtration on the haze formation in bayberry (Myrica rubra Sieb. et Zucc.) juice.
PubMed: Influence of instar and commodity on insecticidal effect of two diatomaceous earth formulations against larvae of Ephestia kuehniella (Lepidoptera: Pyralidae).
PubMed: Susceptibility of different European populations of Tribolium confusum (coleoptera: Tenebrionidae) to five diatomaceous earth formulations.
PubMed: Effect of temperature and humidity on insecticidal effect of SilicoSec against Ephestia kuehniella (Lepidoptera: Pyralidae) larvae.
PubMed: Effect of temperature, exposure interval, and depth of diatomaceous earth treatment on distribution, mortality, and progeny production of lesser grain borer (Coleoptera: Bostrichidae) in stored wheat.
PubMed: Automated method for measuring globin adducts of acrylamide and glycidamide at optimized Edman reaction conditions.
PubMed: Determination of carbendazim residues in fruit juices by liquid chromatography-tandem mass spectrometry.
PubMed: Application of accelerated solvent extraction followed by gel performance chromatography and high-performance liquid chromatography for the determination of polycyclic aromatic hydrocarbons in mussel tissue.
PubMed: Determination of pesticides and PCBs in virgin olive oil by multicolumn solid-phase extraction cleanup followed by GC-NPD/ECD and confirmation by ion-trap GC-MS.
PubMed: A cost-effective screening method for pesticide residue analysis in fruits, vegetables, and cereal grains.
PubMed: Determination of 266 pesticide residues in apple juice by matrix solid-phase dispersion and gas chromatography-mass selective detection.
PubMed: Application of tandem mass spectrometry combined with gas chromatography to the routine analysis of ethyl carbamate in stone-fruit spirits.
PubMed: Improved method to obtain pure alpha-galactosides from lupin seeds.
PubMed: Residues and half-lives of pyrethrins on field-grown pepper and tomato.
PubMed: Optimization of a clean-up procedure for the determination of heterocyclic aromatic amines in urine by field-amplified sample injection-capillary electrophoresis-mass spectrometry.
PubMed: Efficacy of diatomaceous earth to control internal infestations of rice weevil and maize weevil (Coleoptera: Curculionidae).
PubMed: Determination of total fat in milk- and soy-based infant formula powder by supercritical fluid extraction.
PubMed: Synthesis of antioxidant propyl gallate using tannase from Aspergillus niger van Teighem in nonaqueous media.
PubMed: Purification and characterization of molybdenum species from Medicago sativa (alfalfa) grown on mine tailings.
PubMed: Determination of pesticides in composite dietary samples by gas chromatography/mass spectrometry in the selected ion monitoring mode by using a temperature-programmable large volume injector with preseparation column.
PubMed: Immobilization and characterization of ficin.
PubMed: Determination of crude fat in meat by supercritical fluid extraction: direct method: PVM 3:2000.
PubMed: Action of amorphous diatomaceous earth against different stages of the stored product pests Tribolium confusum, Tenebrio molitor, Sitophilus granarius and Plodia interpunctella.
PubMed: Grain surface-layer treatment of diatomaceous earth for insect control.
PubMed: Classification of chili powders by thin-layer chromatography and principal component analysis.
PubMed: Impact of food source on survival of red flour beetles and confused flour beetles (Coleoptera: Tenebrionidae) exposed to diatomaceous earth.
PubMed: Simple method of isolation and purification of alpha-galactosides from legumes.
PubMed: Toxicity of diatomaceous earth to red flour beetles and confused flour beetles (Coleoptera: Tenebrionidae): effects of temperature and relative humidity.
PubMed: Automatic microgravimetric determination of fats in milk products by use of supercritical fluid extraction with on-line piezoelectric detection.
PubMed: Selectivity of celite-immobilized patatin (lipid acyl hydrolase) from potato (Solanum tuberosum L.) tubers in esterification reactions As influenced by water activity and glycerol analogues as alcohol acceptors.
PubMed: Polyphenolic content in five tuscany cultivars of Olea europaea L.
PubMed: Rapid determination of citrinin in corn by fluorescence liquid chromatography and enzyme immunoassay.
PubMed: trans-resveratrol content in commercial peanuts and peanut products.
PubMed: Experimental Induction of Morphological Deformities in Chironomus riparius Larvae by Chronic Exposure to Copper and Lead
PubMed: Comparison of inert markers [chromic oxide or insoluble ash (Celite)] for determining apparent metabolizable energy of wheat- or barley-based broiler diets with or without enzymes.
PubMed: Comparison of the properties of trypsin immobilized on 2 Celite derivatives.
PubMed: [Changes in the lymph nodes of rats under the influence of natural sorbents in damaging exposure to carbophos].
PubMed: Determination and survey of deoxynivalenol in white flour, whole wheat flour, and bran.
PubMed: Multicolumn solid-phase extraction cleanup of organophosphorus and organochlorine pesticide residues in vegetable oils and butterfat.
PubMed: Biogenic amorphous silica.
PubMed: Quantitative determination of heterocyclic amines in food products.
PubMed: Application of solid-phase partition cartridges in the determination of fungicide residues in vegetable samples.
PubMed: Characteristics of beta-lactoglobulin binding to the all-trans-retinal moiety covalently immobilized on Celite.
PubMed: Quantitation of mutagenic/carcinogenic heterocyclic aromatic amines in food products.
PubMed: Enhanced supercritical fluid carbon dioxide extraction of pesticides from foods using pelletized diatomaceous earth.
PubMed: The manipulation of DNA with restriction enzymes in low water systems.
PubMed: Rapid immunochemical screening method for aflatoxin B1 in human and animal urine.
PubMed: Migration testing of plastics and microwave-active materials for high-temperature food-use applications.
PubMed: Simple methods for quantifying mutagenic heterocyclic aromatic amines in food products.
PubMed: Liquid chromatographic-electrochemical determination of ethylenethiourea in foods by revised official method.
PubMed: Liquid chromatographic-atomic absorption spectrophotometric method for determination of methyl mercury in seafood: collaborative study.
PubMed: Improved method for partition of organophosphate pesticide residues on a solid phase partition column.
PubMed: The simultaneous determination of diacetoxyscirpenol and T-2 toxin in fungal cultures and grain samples by capillary gas chromatography.
PubMed: HPLC determination of N-nitrosomethylurea in biological fluids by reaction with 4-nitrothiophenol.
PubMed: Polyamide-kieselguhr thin-layer chromatography of yellow food dyes.
PubMed: [A view on the standard of diatomaceous earth as food additives].
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