zinc orotate, 68399-76-8

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CODE110022 CODE110022
Product(s):
26-32000 ZINC OROTATE

Name:	zinc 2,4-dioxo-1H-pyrimidine-6-carboxylate
CAS Number:	68399-76-8	3D/inchi
ECHA EINECS - REACH Pre-Reg:	269-988-0
FDA UNII:	Z722242H10
MDL:	MFCD00167357
Molecular Weight:	375.55942000
Formula:	C10 H6 N4 O8 Zn
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:nutrient supplements, EFSA concludes: use is of safety concern.

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Perfumer and Flavorist:	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Flash Point:	32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w):	-0.928 (est)
Soluble in:
	water, 2.114e+005 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

Santa Cruz Biotechnology

For experimental / research use only.

Orotic acid zinc salt dihydrate

Sigma-Aldrich: Aldrich

For experimental / research use only.

Orotic acid zinc salt dihydrate ≥98.0%

sds

Safety Information:

Preferred SDS: View

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
nutrient supplements, EFSA concludes: use is of safety concern.
Recommendation for zinc orotate usage levels up to:
	not for fragrance use.

Recommendation for zinc orotate flavor usage levels up to:
	not for flavor use.

Safety References:

European Food Safety Authority (EFSA) reference(s):

Orotic acid salts as sources of orotic acid and various minerals added for nutritional purposes to food supplements
View page or View pdf

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):68399-76-8

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :108934

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

zinc 2,4-dioxo-1H-pyrimidine-6-carboxylate

Chemidplus:0068399768

References:

	zinc 2,4-dioxo-1H-pyrimidine-6-carboxylate
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	108934
Pubchem (sid):	135065433

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
FDA Listing of Food Additive Status:	View
ChemSpider:	View
Wikipedia:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

not found in nature

Synonyms:

	orotic acid zinc salt dihydrate
bis(1,2,3,6-	tetrahydro-2,6-dioxopyrimidine-4-carboxylato-N3,O4)zinc
	zinc 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylate (1:2)
	zinc 2,4-dioxo-1H-pyrimidine-6-carboxylate
	zinc, bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-N3,O4)-, (T-4)-

Articles:

PubMed:Comparative in vitro toxicity of seven zinc-salts towards neuronal PC12 cells.

PubMed:Ineffectiveness of zinc gluconate nasal spray and zinc orotate lozenges in common-cold treatment: a double-blind, placebo-controlled clinical trial.

PubMed:The progression of aging in klotho mutant mice can be modified by dietary phosphorus and zinc.

PubMed:Further studies on selective radioprotection by organic zinc salts and synergism of zinc aspartate with WR 2721.

PubMed:Synergism of organic zinc salts and sulfhydryl compounds (thiols) in the protection of mice against acute ethanol toxicity, and protective effects of various metal salts.

PubMed:Some aspects of a non-linear effect of zinc ions on the histamine release from rat peritoneal mast cells.

PubMed:The bioavailability and pharmacokinetics of three zinc salts: zinc pantothenate, zinc sulfate and zinc orotate.

Notes:

None found

zinc orotate zinc, bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-N3,O4)-, (T-4)-

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Articles:

zinc orotate
zinc, bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylato-N3,O4)-, (T-4)-