EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

sodium propionate
propanoic acid, sodium salt (1:1)

Supplier Sponsors

Name:sodium propanoate
CAS Number: 137-40-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:205-290-4
FDA UNII:391O0PO49R
Nikkaji Web:J4.430J
Beilstein Number:3566934
MDL:MFCD00002759
Molecular Weight:97.06898928
Formula:C3 H6 O2 Na
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:preservatives, antimould and antirope agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1784 Sodium propionate View - review
EU SANCO Sodium propionate View - review
EU SANCO Sodium propionate View - review
JECFA Food Additive: Sodium Propionate
GSFA Codex: Sodium propionate (281)
DG SANTE Food Additives:sodium propionate
FDA Mainterm (SATF):137-40-6 ; SODIUM PROPIONATE
FDA Regulation:
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.123 Cold-pack and club cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.124 Cold-pack cheese food.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.169 Pasteurized process cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.173 Pasteurized process cheese food.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.179 Pasteurized process cheese spread.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.141 Artificially sweetened fruit jelly.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.161 Artificially sweetened fruit preserves and jams.


FDA PART 179 -- IRRADIATION IN THE PRODUCTION, PROCESSING AND HANDLING OF FOOD
Subpart C--Packaging Materials for Irradiated Foods
Sec. 179.45 Packaging materials for use during the irradiation of prepackaged foods.


FDA PART 180 -- FOOD ADDITIVES PERMITTED IN FOOD OR IN CONTACT WITH FOOD ON AN INTERIM BASIS PENDING ADDITIONAL STUDY


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: Yes
Melting Point: 285.00 to 286.00 °C. @ 760.00 mm Hg
Boiling Point: 141.70 °C. @ 760.00 mm Hg (est)
Vapor Pressure:4.230000 mmHg @ 25.00 °C. (est)
Flash Point: 136.00 °F. TCC ( 57.70 °C. ) (est)
logP (o/w): 0.246 (est)
Soluble in:
 alcohol
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor Strength:none
Odor Description:at 100.00 %. bland
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: preservatives
 
Suppliers:
Amecan
Sodium Propionate
BOC Sciences
For experimental / research use only.
Sodium Propionate 99%
ECSA Chemicals
Sodium Propionate
Company Profile
Foodchem International
Sodium Propionate
Graham Chemical
Sodium Propionate
Jarchem Industries
Jarace™ SP
Odor: characteristic
Use: Is used as a food preservative primarily as a mold inhibitor in bakery products.
Kraft Chemical
Sodium Propionate
Penta International
SODIUM PROPIONATE ANHYDROUS FCC GRADE
Penta International
SODIUM PROPIONATE ANHYDROUS NF GRADE
Qingdao Dacon Trading
Sodium Propionate
Santa Cruz Biotechnology
For experimental / research use only.
Sodium Propionate
Sigma-Aldrich
Sodium propionate, FCC
Certified Food Grade Products
Sinofi Food Ingredients
Sodium Propionate
Odor: characteristic
Use: Preservative, Cosmetics, Feed, Antimicrobial, Fungicide, Mold Inhibitor, Flavoring Agent, Baking Food, Beer, Nonalcoholic Beverages, Beverage Powder, Fruit Juice, Cheese, Confections, Frostings, Gelatins, Puddings, Jams, Jellies, Meat Products, Sauces, Sauage, Soft Candy, Tobacco.
TCI AMERICA
For experimental / research use only.
Sodium Propionate >98.0%(T)
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xn - Harmful.
R 21 - Harmful in contact with skin.
R 36/37/38 - Irritating to eyes, respiratory system, and skin.
S 02 - Keep out of the reach of children.
S 22 - Do not breath dust.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 6332 mg/kg
Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. Vol. 28, Pg. 463, 1973.

unreported-mouse LD50 7800 mg/kg
BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(3), Pg. 96, 1970.

unreported-rabbit LD50 6750 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: EXCITEMENT
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(3), Pg. 96, 1970.

unreported-rat LD50 8150 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: EXCITEMENT
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(3), Pg. 96, 1970.

Dermal Toxicity:
skin-rabbit LD50 1640 mg/kg
Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 60, 1949.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: preservatives, antimould and antirope agents
Recommendation for sodium propionate usage levels up to:
 not for fragrance use.
 
Recommendation for sodium propionate flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the safety and efficacy of propionic acid, sodium propionate, calcium propionate and ammonium propionate for all animal species
View page or View pdf

Scientific Opinion on safety and efficacy of sodium benzoate, propionic acid and sodium propionate for pigs, poultry, bovines, sheep, goats, rabbits, horses
View page or View pdf

Scientific Opinion on the re-evaluation of propionic acid (E 280), sodium propionate (E 281), calcium propionate (E 282) and potassium propionate (E 283) as food additives
View page or View pdf

Safety of the extension of use of sodium propionate (E 281) as a food additive
View page or View pdf

EPI System: View
NIOSH International Chemical Safety Cards:search
NLM Hazardous Substances Data Bank:Search
Chemical Carcinogenesis Research Information System:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):137-40-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :2723816
National Institute of Allergy and Infectious Diseases:Data
SCCNFP:opinion
WGK Germany:1
sodium propanoate
Chemidplus:0000137406
RTECS:137-40-6
 
References:
 sodium propanoate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:137-40-6
Pubchem (cid):2723816
Pubchem (sid):134973581
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):D08440
HMDB (The Human Metabolome Database):Search
FooDB:FDB015271
Export Tariff Code:2915.50.5000
FDA Listing of Food Additive Status:View
Haz-Map:View
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
FAO:Sodium propionate
Formulations/Preparations:
•sodium propionate nf; propanoic acid, sodium salt, hydrate •sodium propionate is often compounded with antibiotics or antiseptics. •grades: national formulary; food chemical codex •propionic acid and sodium propionate may be compounded together or with sodium caprulate sodium propionate is used in proprietary preparations in concentrations of 1 to 5%.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 preservatives
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 jarace SP
 propanoic acid sodium salt
 propanoic acid sodium salt (1:1)
 propanoic acid, sodium salt
 propanoic acid, sodium salt (1:1)
 propanoic acid, sodium salt (2:1)
 propionic acid sodium salt
 propionic acid, sodium salt
 sodium propanoate
 sodium propionate anhydrous
 sodium propionate FCC agglomerate
 sodiumpropionate
 

Articles:

PubMed:Influence of the antimicrobial compound allyl isothiocyanate against the Aspergillus parasiticus growth and its aflatoxins production in pizza crust.
PubMed:Effect of food preservatives on the hydration properties and taste behavior of amino acids: a volumetric and viscometric approach.
PubMed:Potassium sorbate reduces production of ethanol and 2 esters in corn silage.
PubMed:High-grain diets suppress ruminal tissue abundance of angiopoietin-like protein 4 in cattle.
PubMed:Development of an alternative culture medium for the selective enumeration of Lactobacillus casei in fermented milk.
PubMed:Effect of preservatives on Shiga toxigenic phages and Shiga toxin of Escherichia coli O157:H7.
PubMed:Effect of antifungal hydroxypropyl methylcellulose-lipid edible composite coatings on Penicillium decay development and postharvest quality of cold-stored "Ortanique" mandarins.
PubMed:Immediate reduction of Salmonella enterica serotype typhimurium viability via membrane destabilization following exposure to multiple-hurdle treatments with heated, acidified organic acid salt solutions.
PubMed:Synergistic reduction of Salmonella in a model raw chicken media using a combined thermal and acidified organic acid salt intervention treatment.
PubMed:Conservation characteristics of wilted perennial ryegrass silage made using biological or chemical additives.
PubMed:Curative and preventive activity of hydroxypropyl methylcellulose-lipid edible composite coatings containing antifungal food additives to control citrus postharvest green and blue molds.
PubMed:Optimization of a reconstituted skim milk based medium for enhanced CLA production by bifidobacteria.
PubMed:Resistance of nutrient-deprived Listeria monocytogenes 10403S and a DeltasigB mutant to chemical stresses in the presence or absence of oxygen.
PubMed:Evaluation of genotoxic effects of sodium propionate, calcium propionate and potassium propionate on the root meristem cells of Allium cepa.
PubMed:Controlling Listeria monocytogenes on sliced ham and turkey products using benzoate, propionate, and sorbate.
PubMed:Biosynthesis of tetrapetalones.
PubMed:Rapid determination of cyclamate in foods by solid-phase extraction and capillary electrophoresis.
PubMed:Inhibition of Listeria monocytogenes in turkey and pork-beef bologna by combinations of sorbate, benzoate, and propionate.
PubMed:[A positive effect of Propionibacterium freudenreichii on the growth of Saccharomyces cerevisiae during their cocultivation].
PubMed:Potential of antimicrobial agents to inhibit fungi to aid isolation of Campylobacter.
PubMed:Effect of immersion solutions containing enterocin AS-48 on Listeria monocytogenes in vegetable foods.
PubMed:Milk whey culture with Propionibacterium freudenreichii ET-3 is effective on the colitis induced by 2,4,6-trinitrobenzene sulfonic acid in rats.
PubMed:Autoinducer-2-like activity associated with foods and its interaction with food additives.
PubMed:The effects of fiber enrichment of pasta and fat content on gastric emptying, GLP-1, glucose, and insulin responses to a meal.
PubMed:Control of Listeria monocytogenes on turkey frankfurters by generally-recognized-as-safe preservatives.
PubMed:Effect of selected generally recognized as safe preservative sprays on growth of Listeria monocytogenes on chicken luncheon meat.
PubMed:Evaluation of food additives and low-toxicity compounds as alternative chemicals for the control of Penicillium digitatum and Penicillium italicum on citrus fruit.
PubMed:Media for the isolation and enumeration of bifidobacteria in dairy products.
PubMed:Measurements of the gastric emptying rate by use of ultrasonography: studies in humans using bread with added sodium propionate.
PubMed:Experimental approach to optimize the use of alpha-Amylases in breadmaking.
PubMed:Effects of food preservatives on Alternaria alternata growth and tenuazonic acid production.
PubMed:Prediction of Listeria spp. growth as affected by various levels of chemicals, pH, temperature and storage time in a model broth.
PubMed:Administration of fatty acids and gonadotrophin secretion in the mature ram.
PubMed:Preference for flavored wheat straw by lambs conditioned with intraruminal infusions of acetate and propionate.
PubMed:Cytotoxicity of food preservatives in cultured rat hepatocytes loaded with linolenic acid.
PubMed:Integration of regulatory signals controlling forage intake in ruminants.
PubMed:Delayed gastric emptying rate as a potential mechanism for lowered glycemia after eating sourdough bread: studies in humans and rats using test products with added organic acids or an organic salt.
PubMed:Preference for flavored wheat straw by lambs conditioned with intraruminal administrations of sodium propionate.
PubMed:Influence of orally and rectally administered propionate on cholesterol and glucose metabolism in obese rats.
PubMed:Metabolic activities of Listeria monocytogenes in the presence of sodium propionate, acetate, lactate and citrate.
PubMed:[Preservation and stability of corn tortillas at room temperature].
PubMed:Administration of propionate to day-old turkeys.
PubMed:Satiety signals in sheep: involvement of CCK, propionate, and vagal CCK binding sites.
PubMed:The voluntary intake of hay and silage by lactating cows in response to ruminal infusion of acetate or propionate, or both, with or without distension of the rumen by a balloon.
PubMed:Lithium chloride-sodium propionate agar for the enumeration of bifidobacteria in fermented dairy products.
PubMed:Sites of action by propionate on Listeria monocytogenes.
PubMed:Propionate lowers blood glucose and alters lipid metabolism in healthy subjects.
PubMed:Behavior of Listeria monocytogenes in the presence of sodium propionate.
PubMed:The roles of hepatic nerves in the reduction of food intake as a consequence of intraportal sodium propionate administration in sheep.
PubMed:Hypocholesterolaemic effects of dietary propionate: studies in whole animals and perfused rat liver.
PubMed:Inhibition by antimicrobial food additives of ochratoxin A production by Aspergillus sulphureus and Penicillium viridicatum.
PubMed:Propionate loading test for liver function during experimental liver necrosis in sheep.
PubMed:Survival in foods of Staphylococcus aureus grown under optimal and stressed conditions and the effect of some food preservatives.
PubMed:Vitamin B12 content in the complex stomach of small ruminants receiving propionic acid and sodium propionate in the food.
 
Notes:
Antimicrobial agent used in cheese and other foods
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