EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

sodium laevo-lactate
propanoic acid, 2-hydroxy-, sodium salt, (2S)- (1:1)

Sponsors

Name:sodium (2S)-2-hydroxypropanoate
CAS Number: 867-56-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:212-762-3
FDA UNII:P2Y1C6M9PS
Nikkaji Web:J1.170C
Beilstein Number:4567087
MDL:MFCD00066576
Molecular Weight:112.06021928
Formula:C3 H5 Na O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:cosmetic and flavor agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
EU SANCO Sodium lactate View-review
 
Physical Properties:
Appearance:colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 227.60 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.015000 mm/Hg @ 25.00 °C. (est)
Flash Point: 230.00 °F. TCC ( 109.90 °C. ) (est)
logP (o/w): -0.698 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
humectants
keratolytics
 
Suppliers:
BOC Sciences
For experimental / research use only.
Sodium (S)-lactate 95%
Carbosynth
For experimental / research use only.
Sodium L-lactate - 40% aq solution
ECSA Chemicals
L-Sodium Lactate 50% Pharma
Company Profile
Jungbunzlauer Suisse
Sodium L(+)-Lactate Blends
Flavor: characteristic
Sodium L(+)-lactate is the sodium salt of L(+)-lactic acid, obtained by neutralisation of the acid of natural origin with a high purity sodium source. Lactate is produced naturally by living organisms as a by-product of the glycolysis. Jungbunzlauer sodium L(+)-lactate is a safe preservative with a high water holding capacity and buffering properties for food and personal care uses.
Jungbunzlauer Suisse
Sodium L(+)-lactate
Santa Cruz Biotechnology
For experimental / research use only.
Sodium L-lactate
Sigma-Aldrich: Sigma
For experimental / research use only.
Sodium L-lactate ∼98%
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: cosmetic and flavor agents
Recommendation for sodium laevo-lactate usage levels up to:
 not for fragrance use.
 
 
Safety References:
EPI System: View
EPA Substance Registry Services (TSCA):867-56-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :23666456
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
sodium (2S)-2-hydroxypropanoate
Chemidplus:0000867561
 
References:
 sodium (2S)-2-hydroxypropanoate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):23666456
Pubchem (sid):134972475
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):D02183
HMDB (The Human Metabolome Database):Search
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
(S)-2-hydroxypropionic acid sodium salt
L-lactic acid sodium salt
 propanoic acid, 2-hydroxy-, monosodium salt, (2S)-
 propanoic acid, 2-hydroxy-, sodium salt, (2S)- (1:1)
 sarcolactic acid sodium salt
 sodium (2S)-2-hydroxypropanoate
 sodium (S)-lactate
 sodium L-lactate
 sodium L(+)-lactate
 

Articles:

PubMed:Mechanistic modeling of monocarboxylate transporter-mediated toxicokinetic/toxicodynamic interactions between ╬│-hydroxybutyrate and L-lactate.
PubMed:Spontaneous supersaturation of calcium D-gluconate during isothermal dissolution of calcium L-lactate in aqueous sodium D-gluconate.
PubMed:Aqueous solubility of calcium L-lactate, calcium D-gluconate, and calcium D-lactobionate: importance of complex formation for solubility increase by hydroxycarboxylate mixtures.
PubMed:Neuroprotective effects of lactate in brain ischemia: dependence on anesthetic drugs.
PubMed:Sodium L-lactate differently affects brain-derived neurothrophic factor, inducible nitric oxide synthase, and heat shock protein 70 kDa production in human astrocytes and SH-SY5Y cultures.
PubMed:Exogenous L-lactate clearance in adult horses.
PubMed:Prevention of acute/severe hypoglycemia-induced neuron death by lactate administration.
PubMed:A method for lactate and pyruvate determination in filter-paper dried blood spots.
PubMed:Effectiveness of combined preservation methods to extend the shelf life of Morcilla de Burgos.
PubMed:Histidine inhibits the degradation of cells suspended in Ringer's lactate.
PubMed:Field-scale demonstration of induced biogeochemical reductive dechlorination at Dover Air Force Base, Dover, Delaware.
PubMed:Optimization of L-lactic acid feeding for the production of poly-D-3-hydroxybutyric acid by Alcaligenes eutrophus in fed-batch culture.
PubMed:Evidence for swelling-induced adenosine and adenine nucleotide release in rat cerebral cortex exposed to monocarboxylate-containing or hypotonic artificial cerebrospinal fluids.
PubMed:Glycolysis prevents anoxia-induced synaptic transmission damage in rat hippocampal slices.
PubMed:Effect of continuous venovenous hemofiltration with dialysis on lactate clearance in critically ill patients.
PubMed:Neurocardiac toxicity of racemic D,L-lactate fluids.
PubMed:Effects of sodium L-lactate and sodium racemic lactate on intraoperative acid-base status.
PubMed:Plasma growth hormone and prolactin responses to graded levels of acute exercise and to a lactate infusion.
PubMed:Stoichiometry of the renal sodium-L-lactate cotransporter.
PubMed:Clinical evaluation of sodium bicarbonate, sodium L-lactate, and sodium acetate for the treatment of acidosis in diarrheic calves.
PubMed:Lactate reverses insulin-induced hypoglycemic stupor in suckling-weanling mice: biochemical correlates in blood, liver, and brain.
PubMed:Comparison of the kinetics and utilisation of D(-)-and L(+)-sodium lactate in normal man.
PubMed:Utilization of L(+) lactate in patients with liver disease.
PubMed:A model of L(+)-lactate metabolism in normal man.
PubMed:Disturbances of lactate metabolism in patients with liver damage due to paracetamol overdose.
PubMed:Facilitated diffusion of lactic acid in the guinea-pig placenta.
PubMed:Preferential uptake of lactate by the normal myocardium in dogs.
PubMed:Is lactate involved in phenformin-induced insulin secretion?
PubMed:Evidence for a role of exogenous or endogenous hyperlactatemia in insulin secretion in the dog.
PubMed:Liver function and lactate metabolism in the ill surgical patient.
PubMed:Nutritional requirements of anaerobic coryneforms.
PubMed:Use of endogenous triglycerides to support gluconeogenesis in the perfused isolated rat liver.
PubMed:Growth hormone secretion in acid-base alterations at rest and during exercise.
PubMed:Influence of lactate infusion on glucose and FFA metabolism in man.
PubMed:Glucagon and insulin control of gluconeogenesis in the perfused isolated rat liver. Effects on cellular metabolite distribution.
PubMed:The effect of exercise on lactate metabolism.
PubMed:Pharmacologic differences between sodium D-lactate and sodium L-lactate in sheep.
PubMed:Metabolic effects of infused sodium L (+) lactate in man before and after triiodothyronine treatment.
PubMed:Relationship between excess respiratory metabolism and utilization of intravenously infused sodium racemic lactate and sodium L(-) lactate.
 
Notes:
None found
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