potassium iodide
potassium salt of hydriodic acid
 
Notes:
an inorganic compound that is used as a source of iodine in thyrotoxic crisis and in the preparation of thyrotoxic patients for thyroidectomy. (from dorland, 27th ed) Nutrient supplement; added to food as a source of iodine [DFC] Potassium iodide is an inorganic compound with the chemical formula KI. The major uses of KI include use as a nutritional supplement in animal feeds and also the human diet. For the latter, it is the most common additive used to "iodize" table salt (a public health measure to prevent iodine deficiency in populations which get little seafood). Kelp is a natural KI source. The iodide content can range from 89 ug/g to 8165 ug/g in Asian varieties, making prepared foods content difficult to estimate. Eating 3-5 grams of most dried, unrinsed seaweeds will provide the 100-150 micrograms iodide recommended daily allowance for nutritional purposes. [Wikipedia]
  • Charkit Chemical
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    • ECSA Chemicals
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      ECSA Group offers its customers in these business segments a complete 'one-stop shopping' solution.
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  • Lansdowne Chemicals
    • Lansdowne Chemicals
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    • Penta International Corporation
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potassium iodide (Click)
CAS Number: 7681-11-0Picture of molecule
ECHA EINECS - REACH Pre-Reg: 231-659-4
FDA UNII: 1C4QK22F9J
Nikkaji Web: J43.931B
MDL: MFCD00011405
Molecular Weight: 166.00277000
Formula: I K
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: nutrient supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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 FDA/DG SANTE Petitions, Reviews, Notices:
184.1634 Potassium iodide View-review
DG SANTE Food Contact Materials: potassium iodide
FDA Mainterm: POTASSIUM IODIDE
FDA Regulation:
FDA PART 100 -- GENERAL
Subpart G--Specific Administrative Rulings and Decisions
Sec. 100.155 Salt and iodized salt.


FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart D--Special Dietary and Nutritional Additives
Sec. 172.375 Potassium iodide.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart B--Substances Utilized To Control the Growth of Microorganisms
Sec. 178.1010 Sanitizing solutions.


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1634 Potassium iodide.


FDA PART 582 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart A--General Provisions
Sec. 582.80 Trace minerals added to animal feeds.
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Physical Properties:
Food Chemicals Codex Listed: No
Soluble in:
 water, 5.894e+004 mg/L @ 25 °C (est)
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antimicrobial agents
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Suppliers:
Allan Chemical
Potassium Iodide Neutral
Allan Chemical
Potassium Iodide
American Elements
Potassium Iodide 99%
Odor: characteristic
Use: Potassium Iodide is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered.
American International Chemical
Potassium Iodide
Charkit Chemical
POTASSIUM IODIDE 45% TECH
Charkit Chemical
POTASSIUM IODIDE USP
Charkit Chemical
POTASSIUM IODIDE, ACS
ECSA Chemicals
Potassium Iodide
Company Profile
Lansdowne Chemicals
Potassium Iodide 68%
Lansdowne Chemicals
Potassium Iodide
Penta International
POTASSIUM IODIDE GRANULAR
Sigma-Aldrich
For experimental / research use only.
Potassium Iodide BioXtra, ≥99.0%
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LDLo  1117 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 120, Pg. 171, 1957.

oral-mouse LDLo  1862 mg/kg
BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Pharmacology and Experimental Therapeutics. Vol. 120, Pg. 171, 1957.

oral-rabbit LDLo  916 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 30, Pg. 407, 1927.

intravenous-rat LDLo  167 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 96, Pg. 292, 1923.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: nutrient supplements
Recommendation for potassium iodide usage levels up to:
 not for fragrance use.
 
Recommendation for potassium iodide flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Scientific Opinion on the safety and efficacy of iodine compounds (E2) as feed additives for all species: calcium iodate anhydrous and potassium iodide, based on a dossier submitted by HELM AG
View page or View pdf
Conclusion on the peer review of the pesticide risk assessment of the active substance potassium iodide
View page or View pdf
Pesticide active substances that do not require a review of the existing maximum residue levels under Article 12 of Regulation (EC) No 396/2005
View page or View pdf
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
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Toxicology Citations: Search
Carcinogenic Potency Database: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 7681-11-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 4875
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 potassium iodide
Chemidplus: 0007681110
EPA/NOAA CAMEO: hazardous materials
RTECS: TT2975000 for cas# 7681-11-0
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References:
 potassium iodide
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 7681-11-0
Pubchem (cid): 4875
Pubchem (sid): 134988352
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
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KEGG (GenomeNet): C08219
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FooDB: FDB015438
Export Tariff Code: 2827.60.2000
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Formulations/Preparations:
•oral: solution: 249 mg (of iodide) per 5 ml pima syrup, (fleming), 1 gml sski, (upsher-smith) tablets: 65 mg thyro-safe (scored), (recip us); 130 mg iosat, (anbec). thyro-block (scored), (medpointe). •available in 99.9995% purity, ultradry grades; 45% solution
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 antimicrobial agents 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 dipotassium diiodide
 potassium diiodide
 potassium iodide (KI)
 potassium iodide ACS
 potassium iodide granular
 potassium iodide USP granular
 potassium monoiodide
 potassium salt of hydriodic acid
 tripotassium triiodide
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Articles:
PubMed: Effect of Excessive Potassium Iodide on Rat Aorta Endothelial Cells.
PubMed: Modelling and optimising of physicochemical features of walnut-oil beverage emulsions by implementation of response surface methodology: effect of preparation conditions on emulsion stability.
PubMed: Risks and management of radiation exposure.
PubMed: Comparison of different preenrichment broths, egg:preenrichment broth ratios, and surface disinfection for the detection of Salmonella enterica ssp. enterica serovar Enteritidis in shell eggs.
PubMed: Effect of cultivar, location and year on total starch, amylose, phosphorus content and starch grain size of high starch potato cultivars for food and industrial processing.
PubMed: Structural variability between starch granules in wild type and in ae high-amylose mutant maize kernels.
PubMed: Determination of iron(III) based on the fluorescence quenching of rhodamine B derivative.
PubMed: Validation of a user-friendly and rapid method for quantifying iodine content of salt.
PubMed: Functional and anionic cellulose-interacting polymers by selective chemo-enzymatic carboxylation of galactose-containing polysaccharides.
PubMed: RESPONSE OF THE U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES IN PROTECTING CIVILIAN AMERICANS IN JAPAN DURING THE FUKUSHIMA NUCLEAR CRISIS.
PubMed: WHO's public health agenda in response to the Fukushima Daiichi nuclear accident.
PubMed: Minimizing the creation of spent pickling liquors in a pickling process with high-concentration hydrochloric acid solutions: mechanism and evaluation method.
PubMed: Arsenic speciation in environmental samples by hydride generation and electrothermal atomic absorption spectrometry.
PubMed: Zinc ion enhances GABA tea-mediated oxidative DNA damage.
PubMed: Influence of incubation conditions on hydrolysis efficiency and iodine enrichment in baker's yeast.
PubMed: Determination of benzoyl peroxide, as benzoic acid, in wheat flour by capillary electrophoresis compared with HPLC.
PubMed: Nutrition in emergencies: Issues involved in ensuring proper nutrition in post-chemical, biological, radiological, and nuclear disaster.
PubMed: The Japanese tsunami and resulting nuclear emergency at the Fukushima Daiichi power facility: technical, radiologic, and response perspectives.
PubMed: Spectroscopic studies of the interaction between pirimicarb and calf thymus DNA.
PubMed: Consuming iodine enriched eggs to solve the iodine deficiency endemic for remote areas in Thailand.
PubMed: A new method for quantifying iodine in a starch-iodine matrix.
PubMed: Biofortification of lettuce (Lactuca sativa L.) with iodine: the effect of iodine form and concentration in the nutrient solution on growth, development and iodine uptake of lettuce grown in water culture.
PubMed: Fractionation of alkali-solubilized hemicelluloses from delignified Populus gansuensis: structure and properties.
PubMed: Hydrolysis of amylopectin by amylolytic enzymes: level of inner chain attack as an important analytical differentiation criterion.
PubMed: Influence of various iodine supplementation levels and two different iodine species on the iodine content of the milk of cows fed rapeseed meal or distillers dried grains with solubles as the protein source.
PubMed: Evaluation of potassium iodide (KI) and ammonium perchlorate (NH4ClO4) to ameliorate 131I- exposure in the rat.
PubMed: History and development of radiation-protective agents.
PubMed: Chlorine dioxide gas from an aqueous solution: reduction of Salmonella in wounds on tomato fruit and movement to sinks in a treatment chamber.
PubMed: Saccharomyces cerevisiae: the effect of different forms and concentrations of iodine on uptake and yeast growth.
PubMed: [Overdose of iodine on expression of CCK gene in rat brains].
PubMed: Determination of iodoacetic acid using liquid chromatography/electrospray tandem mass spectrometry.
PubMed: Comparative sulfur analysis using thermal combustion or inductively coupled plasma methodology and mineral composition of common livestock feedstuffs.
PubMed: Relative stability of selenites and selenates in feed premixes as a function of water activity.
PubMed: A gamma camera re-evaluation of potassium iodide blocking efficiency in mice.
PubMed: Parasiticidal activity of bovine lactoperoxidase against Toxoplasma gondii.
PubMed: Formation of iodoacetic acids during cooking: interaction of iodized table salt with chlorinated drinking water.
PubMed: From the molecular characterization of iodide transporters to the prevention of radioactive iodide exposure.
PubMed: The indirect detection of bleach (sodium hypochlorite) in beverages as evidence of product tampering.
PubMed: Estimation of iodine in salt fortified with iodine & iron.
PubMed: Mechanisms of Bacillus subtilis spore killing by and resistance to an acidic Fe-EDTA-iodide-ethanol formulation.
PubMed: Toxicity and biodistribution of an iodine-131-radiolabelled tumour necrosis-targeting antibody in non-tumour-bearing domestic felines.
PubMed: Stability, dose uniformity, and palatability of three counterterrorism drugs-human subject and electronic tongue studies.
PubMed: [Blocking of the thyroid against I-131 following a nuclear disaster].
PubMed: Stability of salt double-fortified with ferrous fumarate and potassium iodate or iodide under storage and distribution conditions in Kenya.
PubMed: Lack of genotoxicity of potassium iodate in the alkaline comet assay and in the cytokinesis-block micronucleus test. Comparison to potassium bromate.
PubMed: Urinary iodine kinetics after oral loading of potassium iodine.
PubMed: Combating iodine and iron deficiencies through the double fortification of fish sauce, mixed fish sauce, and salt brine.
PubMed: Radiation disasters and children.
PubMed: Determination of peroxyl radical scavenging activity of flavonoids and plant extracts using an automatic potentiometric titrator.
PubMed: Experts advise on potassium iodide use: no protection against "dirty bombs".
PubMed: Dual fortification of salt with iodine and microencapsulated iron: a randomized, double-blind, controlled trial in Moroccan schoolchildren.
PubMed: Iodine stability in salt double-fortified with iron and iodine.
PubMed: [Experimental and clinical study to remove lead and to prevent lead damage of kidney with salt of high dose KI].
PubMed: Community-based salt iodization program administered by hand sprayers: a trial in Mongolia since 1999.
PubMed: FDA offers guidance on prophylaxis for exposure to radioiodines.
PubMed: Optimization and validation of arsenic determination in foods by hydride generation flame atomic absorption spectrometry.
PubMed: Commercial diet induced hypothyroidism due to high iodine. A histological and radiological analysis.
PubMed: Inhibition of lignin peroxidase-mediated oxidation activity by ethylenediamine tetraacetic acid and N-N-N'-N'-tetramethylenediamine.
PubMed: Total plasma malondialdehyde levels in 16 Taiwanese college students determined by various thiobarbituric acid tests and an improved high-performance liquid chromatography-based method.
PubMed: Purification and partial characterization of peroxidase from human term placenta of non-smokers: metabolism of benzo(a)pyrene-7, 8-dihydrodiol.
PubMed: Studies on the carcinogenicity of potassium iodide in F344 rats.
PubMed: Influence of halogen salts on the production of the ochratoxins by Aspergillus ochraceus Wilh.
PubMed: Miscellaneous treatments: thalidomide, potassium iodide, levamisole, clofazimine, colchicine, and D-penicillamine.
PubMed: Evaluation of potential disinfectants for preslaughter broiler crop decontamination.
PubMed: Iron is well absorbed by healthy adults after ingestion of double-fortified (iron and dextran-coated iodine) table salt and urinary iodine excretion is unaffected.
PubMed: Cutaneous small-vessel vasculitis.
PubMed: [On additional measures for prophylaxis of iodine deficiency].
PubMed: Effect of sodium metabisulfite on hydrogen peroxide production in light-exposed pediatric parenteral amino acid solutions.
PubMed: Evaluation and monitoring of iodine deficiency disorders in school children in north-east Thailand.
PubMed: Evaluation of a new enrichment broth for the isolation of Salmonella spp. from poultry products.
PubMed: Successful struggle against iodine deficiency disorders (I.D.D.) in Croatia.
PubMed: The detection of kinetic intermediates during the unfolding of lipoxygenase-1 by urea or guanidine hydrochloride.
PubMed: Determination of shell content in palm kernel cake.
PubMed: The instability of dietary iodine supply over time in an affluent society.
PubMed: Role of disulfide linkages in structure and activity of proteinase inhibitor from horsegram (Dolichos biflorus).
PubMed: [Incidence of endemic goiter--environmental factors and iodine prophylaxis in Southern Poland].
PubMed: Rapid and sensitive determination of nitrite in foods and biological materials by flow injection or high-performance liquid chromatography with chemiluminescence detection.
PubMed: Spectrofluorometric method for determination of the total mercury content in natural waters.
PubMed: An improved method for the measurement of malondialdehyde in biological samples.
PubMed: Hydrogen peroxide generation in a model paediatric parenteral amino acid solution.
PubMed: Iodide prophylaxis in Poland after the Chernobyl reactor accident: benefits and risks.
PubMed: Development of thyroid gland volume during the first 3 months of life in breast-fed versus iodine-supplemented and iodine-free formula-fed infants.
PubMed: Continuous flow vapor generation for inductively coupled argon plasma spectrometric analysis. Part 2. Arsenic.
PubMed: Determination of antimony in drinking waters by an inexpensive, reproducible hydride generator for atomic spectroscopy.
PubMed: Distribution of elastic fibres in the developing rabbit craniomandibular joint.
PubMed: [Study on consequences of radioactive iodine pollution and iodine prophylaxis after the Czernobyl accident in the Krakow region].
PubMed: [Evaluation of equivalent body burden in the thyroid for the people of Poland on results of 131I absorption after the disaster in Czernobyl. Determination of thyroid blockade with potassium iodide].
PubMed: Determination of N-nitroso compounds by high-performance liquid chromatography with postcolumn reaction and a thermal energy analyzer.
PubMed: Iodine in milk and meat of dairy cows fed different amounts of potassium iodide or ethylenediamine dihydroiodide.
PubMed: Potassium iodide as a thyroid blocker--Three Mile Island to today.
PubMed: Screening method for determination of high levels of cadmium, lead, and copper in foods by polarized Zeeman atomic absorption spectrometry using discrete nebulization technique.
PubMed: Triiodothyronine improves the primary antibody response to sheep red blood cells in severely undernourished weanling mice.
PubMed: Microscopic detection of potato adulteration of prepared horseradish.
PubMed: The reactor accident at Chernobyl: a nuclear medicine practitioner's perspective.
PubMed: Reduction of 85Sr, 137Cs, 131I and 141Ce retention in rats by simultaneous oral administration of calcium alginate, ferrihexacyanoferrate(II), KI and Zn-DTPA.
PubMed: Developmental toxicity and psychotoxicity of potassium iodide in rats: a case for the inclusion of behaviour in toxicological assessment.
PubMed: Need for standards for health food products.
PubMed: [Dietary iodine deficiency in East Germany].
PubMed: Recommendations on the use of potassium iodide as a thyroid-blocking agent in radiation accidents: an FDA update.
PubMed: [Harmful elements in various types of Polish kitchen salt].
PubMed: Final recommendations issued on potassium iodide.
PubMed: Potassium iodide policy.
PubMed: Determination of ascorbic acid with o-iodosobenzoate: analysis of mixtures of ascorbic acid with methionine and cysteine or glutathione.
PubMed: Fast action.
PubMed: Mobilizing for Three Mile Island--the disaster that wasn't.
PubMed: The effect of iodine supplementation on the reproductive rates of goats and sheep.
PubMed: Selenium in foods: evaluation of atomic absorption spectrometric techniques involving hydrogen selenide generation and carbon furnace atomization.
PubMed: Current regulatory status of foods for special dietary uses.
PubMed: The aetiology and prophylaxis of endemic goitre and cretinism. The New Zealnd experience.
PubMed: Letter: Iodized salt.
PubMed: The Kangra valley experiment: prevention of Himalayan endemic goitre with iodinated salt.
PubMed: Results of longterm iodine prophylaxis of endemic goiter in Yugoslavia.
PubMed: Prevention of endemic goitre with iodized salt.
PubMed: Iodide-induced thyrotoxicosis.
PubMed: Spot test for lipoxygenase activity.
PubMed: Goitre studies in Tasmania. 16 Years' prophylaxis with iodide.
PubMed: [Dependence of alkaline salt evaporation on the glowing temperature].
PubMed: [Lead poisoning].
PubMed: Iodine-131 retention in calves.
PubMed: History of the prevention of endemic goitre.
PubMed: [Early clinical findings on the use of P.A.S. associated with potassium iodide in cases of tuberculosis in children].
PubMed: New Zealand Views on Goitre.
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